John P Neoptolemos

John P Neoptolemos

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John P Neoptolemos

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Response to: Comment on "The Impact of Positive Resection Margins on Survival and Recurrence Following Resection and Adjuvant Chemotherapy for Pancreatic Ductal Adenocarcinoma." By Niccolo Petrucciani, MD, PhD, FACS, Laura Antolino, MD, Giovanni Moschetta, MD, Giovanni Ramacciato, MD, FACS.

Ann Surg 2019 May 9. Epub 2019 May 9.

The Department of Surgery, University of Heidelberg, Heidelberg, Germany The Department of Surgery, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK The Department of Surgery, University Hospital Halle, Martin-Luther-University Halle-Wittenberg, Germany The Department of Surgery, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK The Department of Surgery, University of Heidelberg, Heidelberg, Germany.

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http://Insights.ovid.com/crossref?an=00000658-900000000-9509
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http://dx.doi.org/10.1097/SLA.0000000000003371DOI Listing
May 2019

Adjuvant treatment for pancreatic cancer.

Transl Gastroenterol Hepatol 2019 29;4:27. Epub 2019 Apr 29.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.21037/tgh.2019.04.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509427PMC
April 2019

Chemotherapy for pancreatic cancer.

Presse Med 2019 Mar 15;48(3 Pt 2):e159-e174. Epub 2019 Mar 15.

Heidelberg University Hospital, Department of Surgery, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.lpm.2019.02.025DOI Listing
March 2019

Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer.

Ann Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000003270DOI Listing
March 2019

Neoadjuvant and adjuvant chemotherapy in pancreatic cancer.

Langenbecks Arch Surg 2018 Dec 5;403(8):917-932. Epub 2018 Nov 5.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/s00423-018-1724-8
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http://dx.doi.org/10.1007/s00423-018-1724-8DOI Listing
December 2018

S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes.

BMC Cancer 2018 Dec 17;18(1):1255. Epub 2018 Dec 17.

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, The University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1186/s12885-018-5161-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296088PMC
December 2018

Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker.

Oncotarget 2018 Aug 31;9(68):32984-32996. Epub 2018 Aug 31.

Cancer Research Program, IMIM, Hospital del Mar Medical Research Institute, Unidad Asociade CSIC, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.26034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152472PMC
August 2018

Therapeutic developments in pancreatic cancer: current and future perspectives.

Nat Rev Gastroenterol Hepatol 2018 06;15(6):333-348

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1038/s41575-018-0005-xDOI Listing
June 2018

Pancreatic Cancer and FOLFIRINOX: Should We Resect All Responders?

Ann Surg 2018 02;267(2):e35-e36

NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.

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http://dx.doi.org/10.1097/SLA.0000000000002026DOI Listing
February 2018

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Authors:
Alison P Klein Brian M Wolpin Harvey A Risch Rachael Z Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J Childs Jason W Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A Arslan Ana Babic William R Bamlet Laura Beane-Freeman Sonja I Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G Chaffee Charles C Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J Michael M Gaziano Maria Gazouli Graham G Giles Edward Giovannucci Michael Goggins Gary E Goodman Phyllis J Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Eric J Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A Klein Manolis Kogevinas Charles Kooperberg Matthew H Kulke Juozas Kupcinskas Robert J Kurtz Daniel Laheru Stefano Landi Rita T Lawlor I-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L Milne Beatrice Mohelníková-Duchoňová Rachel E Neale John P Neoptolemos Ann L Oberg Sara H Olson Irene Orlow Claudio Pasquali Alpa V Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X Real Nathaniel Rothman Ghislaine Scelo Howard D Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D Thornquist Geoffrey S Tobias Stephen K Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M Petersen Laufey T Amundadottir

Nat Commun 2018 02 8;9(1):556. Epub 2018 Feb 8.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-02942-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805680PMC
February 2018

Chronic pancreatitis.

Nat Rev Dis Primers 2017 Sep 7;3:17060. Epub 2017 Sep 7.

Department of General Surgery, University of Heidelberg, Heidelberg, Germany.

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http://www.nature.com/articles/nrdp201760
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http://dx.doi.org/10.1038/nrdp.2017.60DOI Listing
September 2017

Management and Outcome of 64 Patients with Pancreatic Serous Cystic Neoplasms.

Dig Surg 2016 27;33(3):203-12. Epub 2016 Feb 27.

National Institutes of Health Research Liverpool Pancreas Biomedical Research Unit and Clinical Directorate of General Surgery, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1159/000442094DOI Listing
June 2017

Beyond ESPAC-4: better surgery and systemic therapy.

Lancet 2017 04;389(10078):1517-1518

Department of General, Abdominal and Transplant Surgery, University of Heidelberg, Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736173094
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http://dx.doi.org/10.1016/S0140-6736(17)30947-9DOI Listing
April 2017

Evidence-based Guidelines for the Management of Exocrine Pancreatic Insufficiency After Pancreatic Surgery.

Ann Surg 2016 Dec;264(6):949-958

*Department of Surgery, Hospital Clinico, University of Valencia, Valencia, Spain †Department of Surgery, Complejo Hospitalario Universitario de Vigo, Vigo, Spain ‡Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands §Department of Gastroenterology, Consorci Sanitari de Terrassa, Terrassa, Spain ¶Department of Gastroenterology, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain ||Department of Surgery, Università Vita e Salute, Ospedale San Raffaele IRCCS, Milano, Italy **Department of Surgery, Institut de Malalties Digestives I Metabòliques, Hospital Clínic, IDIBAPS, Barcelona, Spain ††Department of Medicine, Pancreas Center, University of Verona, Verona, Italy ‡‡Department of Endocrinology and Nutrition, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain. §§Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ¶¶Department of Surgery, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain. ||||Department of Surgery, Hospital Universitario de La Princesa, Madrid, Spain ***Department of Gastroenterology, Complejo Hospitalario de Navarra, Pamplona, Spain †††Unidad de Cirugía Hepato-bilio-pancreática y Trasplante, Hospital Universitari i Politecnic. La Fe, Valencia, Spain ‡‡‡NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK §§§Department of Gastroenterology, Hospital Clinico, University of Valencia, Valencia, Spain ¶¶¶Unit of Digestive Disease, Agencia Sanitaria Costa del Sol, Marbella, Málaga ||||||Department Digestive System, Sant'Orsola-Malpighi Hospital, Bologna, Italy ****Department of Surgery, Hospital Universitario de Guadalajara, Guadalajara, Spain ††††Department of HPB Surgery and Liver Transplantation, Hospital Carlos Haya, Malaga, Spain ‡‡‡‡Exocrine Pancreas Research Unit, Hospital Universitari Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, CIBEREHD, Barcelona, Spain §§§§Department of Digestive Surgery- Division of HBP Surgery, Hospital Universitario Donostia, San Sebastián, Spain ¶¶¶¶Department of Gastroenterology, Institut de Malalties Digestives i Metabòliques, Hospital Clínic, IDIBAPS, CiberEHD, Barcelona, Spain ||||||||Department of Gastroenterology, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante, Alicante, Spain.

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http://dx.doi.org/10.1097/SLA.0000000000001732DOI Listing
December 2016

Outcomes From Minimal Access Retroperitoneal and Open Pancreatic Necrosectomy in 394 Patients With Necrotizing Pancreatitis.

Ann Surg 2016 May;263(5):992-1001

*Clinical Directorate of General Surgery, National Institutes of Health Research Liverpool Pancreas Biomedical Research Unit, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK †Liverpool Clinical Trials Unit, University of Liverpool, Liverpool, UK ‡Clinical Directorate of Radiology, National Institutes of Health Research Liverpool Pancreas Biomedical Research Unit, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK §Clinical Directorate of Gastroenterology, National Institutes of Health Research Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital NHS Trust, Liverpool, UK.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/SLA.0000000000001407DOI Listing
May 2016

Stratification of pancreatic tissue samples for molecular studies: RNA-based cellular annotation procedure.

Pancreatology 2015 Jul-Aug;15(4):423-31. Epub 2015 Jun 15.

Functional Genome Analysis, German Research Cancer Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.pan.2015.05.480DOI Listing
April 2016

Pancreatic cancer.

Nat Rev Dis Primers 2016 04 21;2:16022. Epub 2016 Apr 21.

NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Duncan Building, Daulby Street, Liverpool L69 3GA, UK.

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http://dx.doi.org/10.1038/nrdp.2016.22DOI Listing
April 2016

Xanthogranulomatous pancreatitis associated with a mucinous cystic neoplam.

Pathol Int 2016 03 12;66(3):174-176. Epub 2015 Nov 12.

National Institute for Health Research Liverpool Pancreas Biomedical Research Unit, Liverpool, UK.

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http://dx.doi.org/10.1111/pin.12356DOI Listing
March 2016

Immunobiological effects of gemcitabine and capecitabine combination chemotherapy in advanced pancreatic ductal adenocarcinoma.

Br J Cancer 2016 Mar 4;114(5):510-8. Epub 2016 Feb 4.

National Institutes of Health Research Liverpool Pancreas Biomedical Research Unit and Clinical Directorate of General Surgery, Royal Liverpool and Broadgreen University Hospitals NHS Trust and the University of Liverpool, Liverpool L69 3GA, UK.

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http://dx.doi.org/10.1038/bjc.2015.468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782200PMC
March 2016

PANasta Trial; Cattell Warren versus Blumgart techniques of panreatico-jejunostomy following pancreato-duodenectomy: Study protocol for a randomized controlled trial.

Trials 2016 Jan 15;17:30. Epub 2016 Jan 15.

National Institutes of Health Research Liverpool Pancreas Biomedical Research Unit and Clinical Directorate of General Surgery, Royal Liverpool and Broadgreen University Hospitals NHS Trust and the University of Liverpool, Liverpool, L69 3GA, UK.

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http://dx.doi.org/10.1186/s13063-015-1144-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714471PMC
January 2016

What Is the Best Way to Identify Malignant Transformation Within Pancreatic IPMN: A Systematic Review and Meta-Analyses.

Clin Transl Gastroenterol 2015 Dec 10;6:e130. Epub 2015 Dec 10.

NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1038/ctg.2015.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816095PMC
December 2015

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.

Nat Genet 2015 Aug 22;47(8):911-6. Epub 2015 Jun 22.

1] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. [2] Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ng.3341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520746PMC
August 2015

Incidence of post-ERCP pancreatitis from direct pancreatic juice collection in hereditary pancreatitis and familial pancreatic cancer before and after the introduction of prophylactic pancreatic stents and rectal diclofenac.

Pancreas 2015 Mar;44(2):260-5

From the *National Institute for Health Research Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital; †Liverpool Clinical Trials Unit; Departments of ‡Gastroenterology, and §Radiology, Royal Liverpool University Hospital, Liverpool; and ║Digestive Diseases Biomedical Research Unit, National Institute for Health Research Nottingham, Queen's Medical Centre, Nottingham, United Kingdom.

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http://dx.doi.org/10.1097/MPA.0000000000000246DOI Listing
March 2015

Pancreatic mass in a young CFTR carrier with a heterozygous p.R117H CFTR gene mutation and homozygous 7T.

Pancreas 2015 Mar;44(2):343-5

National Institute for Health Research Liverpool Pancreas Biomedical Research Unit Royal Liverpool University Hospital Liverpool, UK Department of Cellular Pathology Royal Liverpool University Hospital Liverpool, UK National Institute for Health Research Liverpool Pancreas Biomedical Research Unit Royal Liverpool University Hospital Liverpool, UK National Institute for Health Research Liverpool Pancreas Biomedical Research Unit Royal Liverpool University Hospital Liverpool, UK

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http://dx.doi.org/10.1097/MPA.0000000000000244DOI Listing
March 2015

Serum cytokine biomarker panels for discriminating pancreatic cancer from benign pancreatic disease.

Mol Cancer 2014 May 20;13:114. Epub 2014 May 20.

NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool and Broadgreen University Hospital NHS Trust, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool L69 3GA, UK.

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http://dx.doi.org/10.1186/1476-4598-13-114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032456PMC
May 2014

Prognostic markers in acute pancreatitis.

Expert Rev Mol Diagn 2014 Apr;14(3):333-46

NIHR Pancreas Biomedical Research Unit, the Royal Liverpool University and Broadgreen Hospitals NHS Trust and the University of Liverpool, Liverpool L69 3GA, UK.

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http://dx.doi.org/10.1586/14737159.2014.897608DOI Listing
April 2014

Optimal duration and timing of adjuvant chemotherapy after definitive surgery for ductal adenocarcinoma of the pancreas: ongoing lessons from the ESPAC-3 study.

J Clin Oncol 2014 Feb 13;32(6):504-12. Epub 2014 Jan 13.

Juan W. Valle, Derek O'Reilly, Manchester Academic Health Sciences Centre, Christie Hospital NHS Foundation Trust and University of Manchester, Manchester; Richard Jackson, Trevor Cox, John P. Neoptolemos, Paula Ghaneh, Charlotte L. Rawcliffe, Liverpool Cancer Research UK Centre and the National Institute for Health Research Pancreas Biomedical Research Unit, University of Liverpool, Liverpool; Daniel Palmer, the Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust; Deborah D. Stocken, the Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham; David Cunningham, Royal Marsden Hospital Foundation Trust, Sutton; Mark R. Middleton, Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford; Alan Anthoney, The Leeds Teaching Hospital Trust, Leeds; Kate Sumpter, Freeman Hospital, Newcastle upon Tyne; Ross Carter, Glasgow Royal Infirmary, Glasgow, United Kingdom; Claudio Bassi, Giovanni Butturini, University of Verona, Verona, Italy; David Goldstein, Bridget A. Robinson, Christos Karapetis, the Australasian Gastro-Intestinal Trials Group, Camperdown, Australia; Andrew Scarfe, University of Alberta, Edmonton, Canada; Francois Lacaine, Hôpital TENON, Assistance Publique Hôpitaux de Paris, Universite Pierre Et Marie Curie, Paris, France; Juhani Sand, Tampere University Hospital, Tampere, Finland; Jakob R. Izbicki, University of Hamburg, Hamburg; Julia Mayerle, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald; Markus W. Büchler, University of Heidelberg, Heidelberg, Germany; Christos Dervenis, the Agia Olga Hospital, Athens, Greece; Attila Oláh, the Petz Aladar Hospital, Gyor, Hungary; Pehr A. Lind, Karolinska-Stockholm Söder Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1200/JCO.2013.50.7657DOI Listing
February 2014

Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial.

J Natl Cancer Inst 2014 Jan 3;106(1):djt347. Epub 2013 Dec 3.

Affiliations of authors: Liverpool Cancer Research UK Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK (WG, JPN, EG, TFC, PG, EC, CMH, CLR, FC, RJ); the Princess Margaret Hospital, Toronto, Canada (MJM); Manchester Academic Health Sciences Centre, Christie NHS Foundation Trust, School of Cancer and Enabling Sciences, University of Manchester, UK (JWV); Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK (DHP); Beatson West of Scotland Cancer Centre, Glasgow, UK (ACM); Glasgow Royal Infirmary, Glasgow, UK (RC); Hôpital Tenon, Université, Pierre et Marie Curie, Paris, France (FL); Austin Health, Melbourne, Australia (NCT); Prince of Wales Hospital and Clinical School University of New South Wales, New South Wales, Australia (DG); Nepean Cancer Centre and University of Sydney, Sydney, Australia (JS); Agia Olga Hospital, Athens, Greece (CD); Medical Oncology, Clatterbridge Centre for Oncology, Bebington, Merseyside, UK (DS); Department of Oncology, Akademiska Sjukhuset, Uppsala University, Uppsala, Sweden (BG); University Hospital, North Staffordshire, UK (MD); Freeman Hospital, Newcastle upon Tyne, UK (RMC); Service de Chirurgie Digestive et Viscérale, Hôpital Tenon, Paris, France (FL); Cross Cancer Institute and University of Alberta, Alberta, Canada (JRM, AGS); Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, UK (MRM); St James's University Hospital, Leeds, UK (AA); Department of Medicine A, University Medicine Greifswald, Greifswald, Germany (JM); Petz Aladar Hospital, Gyor, Hungary (AO); Departments of Surgery and Pathology and ARC-NET Research Center, University of Verona, Italy (AS, CB); Department of Surgery, University of Heidelberg, Heidelberg, Germany (MWB).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djt347DOI Listing
January 2014

Bayesian analysis unravels pancreas-cancer adjuvant therapy.

Lancet Oncol 2013 Oct 12;14(11):1034-1035. Epub 2013 Sep 12.

Cancer Research UK Liverpool Cancer Trials Unit, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, UK; NIHR Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Liverpool, L69 3GA, UK.

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http://dx.doi.org/10.1016/S1470-2045(13)70403-0DOI Listing
October 2013

Adjuvant therapy for pancreatic cancer.

Recent Results Cancer Res 2012 ;196:65-88

Department of Molecular and Clinical Cancer Medicine Centre, University of Liverpool, Liverpool, L69 3GA, UK.

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http://dx.doi.org/10.1007/978-3-642-31629-6_5DOI Listing
April 2013

New biomarkers and targets in pancreatic cancer and their application to treatment.

Nat Rev Gastroenterol Hepatol 2012 Aug 26;9(8):435-44. Epub 2012 Jun 26.

National Institute for Health Research Pancreas Biomedical Research Unit and Liverpool Cancer Research UK Centre, Department of Molecular, University of Liverpool, Liverpool, L69 3GA, UK.

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http://dx.doi.org/10.1038/nrgastro.2012.119DOI Listing
August 2012

Partial pancreatic resection for pancreatic malignancy is associated with sustained pancreatic exocrine failure and reduced quality of life: a prospective study.

Pancreatology 2011 15;11(6):535-45. Epub 2011 Nov 15.

Department of Molecular and Clinical Cancer Medicine, University of Liverpool, and National Institute for Pancreas Biomedical Research Unit, Liverpool, UK.

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http://dx.doi.org/10.1159/000333308DOI Listing
July 2012

Nanotechnology advances in upper gastrointestinal, liver and pancreatic cancer.

Expert Rev Gastroenterol Hepatol 2012 Jun;6(3):343-56

Liverpool Cancer Research UK Centre, Department of Molecular and Clinical Cancer Studies, University of Liverpool, Daulby Street, Liverpool, L69 3GA, UK.

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http://dx.doi.org/10.1586/egh.12.13DOI Listing
June 2012

Understanding metastasis in pancreatic cancer: a call for new clinical approaches.

Cell 2012 Jan;148(1-2):21-3

Li Ka Shing Centre, Cancer Research UK Cambridge Research Institute, Robinson Way, Cambridge CB2 0RE, UK.

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http://dx.doi.org/10.1016/j.cell.2011.12.021DOI Listing
January 2012

Circulating microRNAs as potential markers of human drug-induced liver injury.

Hepatology 2011 Nov;54(5):1767-76

MRC Center for Drug Safety Science, Department of Clinical and Molecular Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1002/hep.24538DOI Listing
November 2011

Adjuvant treatment of pancreatic cancer.

Eur J Cancer 2011 Sep;47 Suppl 3:S378-80

National Institute for Health Research Pancreas Biomédical Research Unit and the Department of Molecular and Clinical Cancer Medicine, Liverpool Cancer Research UK Centre, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/S0959-8049(11)70210-6DOI Listing
September 2011

Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells.

Gastroenterology 2011 Jun 24;140(7):2116-25. Epub 2011 Feb 24.

Physiological Laboratory, University of Liverpool, National Institute for Health Research Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Liverpool.

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http://dx.doi.org/10.1053/j.gastro.2011.02.054DOI Listing
June 2011

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.

Mol Cancer 2011 Apr 13;10:37. Epub 2011 Apr 13.

MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, UK.

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http://dx.doi.org/10.1186/1476-4598-10-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098205PMC
April 2011

Adjuvant therapy in pancreatic cancer.

Dig Dis 2010 18;28(4-5):684-92. Epub 2010 Nov 18.

Division of Surgery and Oncology, School of Cancer Studies, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1159/000320099DOI Listing
March 2011

Pancreatic cancer in 2010: new insights for early intervention and detection.

Nat Rev Gastroenterol Hepatol 2011 Feb;8(2):71-3

Liverpool CR-UK Centre, NIHR Pancreas Biomedical Research Unit, Department of Molecular and Clinical Cancer Medicine, Daulby Street, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1038/nrgastro.2010.214DOI Listing
February 2011

Analysis of serum proteins by LC-MS/MS.

Methods Mol Biol 2010 ;658:281-91

Division of Surgery and Oncology, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1007/978-1-60761-780-8_17DOI Listing
December 2010

Pancreatic cancer: proteomic approaches to a challenging disease.

Pancreatology 2009 4;9(5):567-76. Epub 2009 Aug 4.

Division of Surgery and Oncology, Royal Liverpool University Hospital, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1159/000212083DOI Listing
February 2010

A preoperative prognostic score for resected pancreatic and periampullary neuroendocrine tumours.

Pancreatology 2009 14;9(5):670-6. Epub 2009 Aug 14.

Division of Surgery and Oncology, School of Cancer Studies, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1159/000181179DOI Listing
February 2010

A technically detailed and pragmatic protocol for quantitative serum proteomics using iTRAQ.

J Proteomics 2009 Dec 3;73(2):352-6. Epub 2009 Aug 3.

Royal Liverpool University Hospital, University of Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/j.jprot.2009.07.009DOI Listing
December 2009

Classification of R1 resections for pancreatic cancer: the prognostic relevance of tumour involvement within 1 mm of a resection margin.

Histopathology 2009 Sep;55(3):277-83

Department of Pathology, School of Cancer Studies, University of Liverpool, Royal Liverpool University Hospital, , 5th Floor Duncan Building, Daulby Street, Liverpool L69 3GA, UK.

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http://dx.doi.org/10.1111/j.1365-2559.2009.03376.xDOI Listing
September 2009