John P Cooke

John P Cooke

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John P Cooke

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Asymmetric dimethylarginine predicts impaired epicardial coronary vasomotion in patients with angina in the absence of obstructive coronary artery disease.

Int J Cardiol 2020 Jan 19;299:7-11. Epub 2019 Jul 19.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.07.062DOI Listing
January 2020

Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase.

Metabolism 2019 Nov 30;100:153962. Epub 2019 Aug 30.

Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.153962DOI Listing
November 2019

Dietary Supplements: Facts and Fallacies.

Methodist Debakey Cardiovasc J 2019 Jul-Sep;15(3):169-170

HOUSTON METHODIST DEBAKEY HEART & VASCULAR CENTER, HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.

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http://dx.doi.org/10.14797/mdcj-15-3-169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822645PMC
November 2019

Cardiovascular Risk of Proton Pump Inhibitors.

Methodist Debakey Cardiovasc J 2019 Jul-Sep;15(3):214-219

HOUSTON METHODIST RESEARCH INSTITUTE, HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.

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http://dx.doi.org/10.14797/mdcj-15-3-214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822659PMC
November 2019

A Rare Presentation of Paraneoplastic Striatal Encephalitis Associated with Nonsmall Cell Lung Cancer.

Mov Disord Clin Pract 2019 Nov 30;6(8):711-715. Epub 2019 Oct 30.

Department of Medicine for the Elderly University Hospital Waterford Waterford Ireland.

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http://dx.doi.org/10.1002/mdc3.12848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856451PMC
November 2019

Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome.

Cell Cycle 2019 Oct 14;18(19):2495-2508. Epub 2019 Aug 14.

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute , Houston , TX , USA.

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http://dx.doi.org/10.1080/15384101.2019.1651587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738911PMC
October 2019

Nuclear -Nitrosylation Defines an Optimal Zone for Inducing Pluripotency.

Circulation 2019 Sep 15;140(13):1081-1099. Epub 2019 Aug 15.

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX (P.K.C., S.M., K.C., J.P.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.042371DOI Listing
September 2019

Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.

Aging Cell 2019 Aug 31;18(4):e12979. Epub 2019 May 31.

Department of Cell Biology, UT Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1111/acel.12979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612639PMC
August 2019

Inflammation and Its Role in Regeneration and Repair.

Authors:
John P Cooke

Circ Res 2019 Apr;124(8):1166-1168

From the Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6578588PMC
April 2019

Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage.

Circulation 2019 01;139(1):119-133

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration (L.L., J.P.C.), Houston Methodist Research Institute, TX.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311718PMC
January 2019

TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway.

Circulation 2018 08;138(9):913-928

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.033939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139092PMC
August 2018

Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes.

Mol Cancer Res 2018 08 28;16(8):1209-1214. Epub 2018 Mar 28.

Department of Radiation Oncology, the Houston Methodist Research Institute, Weil Cornell Medical College, Houston, Texas.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072560PMC
August 2018

Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B.

Stem Cells 2018 08 22;36(8):1198-1209. Epub 2018 Apr 22.

Department of Medicine, Division of Cardiology, Mandel Center for Heart and Vascular Research, and the Duke Cardiovascular Research Center, Duke University Medical Center, Durham, North California, USA.

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http://dx.doi.org/10.1002/stem.2833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105371PMC
August 2018

Novel Markers for Adverse Events in Atrial Fibrillation.

J Am Coll Cardiol 2018 08;72(7):734-737

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, Texas.

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http://dx.doi.org/10.1016/j.jacc.2018.04.091DOI Listing
August 2018

Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming.

Antioxid Redox Signal 2018 07 26;29(2):205-218. Epub 2018 Apr 26.

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute , Houston, Texas.

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http://dx.doi.org/10.1089/ars.2017.7364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003401PMC
July 2018

Inflammation-targeted vascular nanomedicine.

Nat Biomed Eng 2018 05;2(5):269-270

Kostas Center for Cardiovascular Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41551-018-0241-yDOI Listing
May 2018

Lmo2 (LIM-Domain-Only 2) Modulates Sphk1 (Sphingosine Kinase) and Promotes Endothelial Cell Migration.

Arterioscler Thromb Vasc Biol 2017 10 3;37(10):1860-1868. Epub 2017 Aug 3.

From the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX.

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http://dx.doi.org/10.1161/ATVBAHA.117.309609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637529PMC
October 2017

Transflammation: Innate immune signaling in nuclear reprogramming.

Adv Drug Deliv Rev 2017 10 13;120:133-141. Epub 2017 Sep 13.

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute (HMRI), 6670 Bertner Ave, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2017.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705345PMC
October 2017

Telomerase mRNA Reverses Senescence in Progeria Cells.

J Am Coll Cardiol 2017 08;70(6):804-805

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http://dx.doi.org/10.1016/j.jacc.2017.06.017DOI Listing
August 2017

A Missing LNC in Vascular Diseases.

Circ Res 2017 08;121(4):320-322

From the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX (J.P.C.); and Division of Vascular Surgery, Stanford University School of Medicine, CA (N.J.L.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637485PMC
August 2017

Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function.

Circ Res 2017 Jun 10;120(12):1947-1957. Epub 2017 May 10.

From the Department of Medicine, College of Medicine, University of Florida, Gainesville (M.S., E.W., J.J.S., J.Z., C.J.P., C.R.C.); Regenerative Medicine Research, Texas Heart Institute, CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston (M.R., D.A.T.); Department of Medicine, University of Louisville, KY (R.B.); Department of Cardiovascular Sciences, Methodist DeBakey Heart and Vascular Center, the Houston Methodist Research Institute, TX (J.P.C.); Interdisciplinary Stem Cell Institute, University of Miami School of Medicine, FL (J.M.H., A.K.); Department of Medicine, Cedars-Sinai Heart Institute, Los Angeles, CA (T.D.H.); Department of Cardiology, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, MN (J.H.T.); and Department of Cardiovascular Medicine, Stanford University, School of Medicine, CA (P.C.Y.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508725PMC
June 2017

The senescence accelerated mouse prone 8 (SAMP8): A novel murine model for cardiac aging.

Ageing Res Rev 2017 May 5;35:291-296. Epub 2016 Nov 5.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2016.10.006DOI Listing
May 2017

A comparison of the pro-angiogenic potential of human induced pluripotent stem cell derived endothelial cells and induced endothelial cells in a murine model of peripheral arterial disease.

Int J Cardiol 2017 May 31;234:81-89. Epub 2017 Jan 31.

Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Camperdown, NSW 2006, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.01.125DOI Listing
May 2017

Retinoic Acid Inducible Gene 1 Protein (RIG1)-Like Receptor Pathway Is Required for Efficient Nuclear Reprogramming.

Stem Cells 2017 05 27;35(5):1197-1207. Epub 2017 Mar 27.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, Texas, 77030, USA.

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http://dx.doi.org/10.1002/stem.2607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426114PMC
May 2017

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling.

Circ Res 2017 May 21;120(11):1727-1739. Epub 2017 Mar 21.

From the Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences (R.M., S.M., Q.G., R.A.-G., Q.Y., J.P.C., L.F.), Houston Methodist DeBakey Heart and Vascular Center, Department of Cardiology (R.A.-G., K.A.Y.), Department of Bioenergetics (H.J.P.), Houston Methodist Research Institute, TX; Department of Ophthalmology, Baylor College of Medicine, Houston, TX (S.K., Y.F.); and Department of Medicine, University of California, San Diego, La Jolla (F.A., Y.I.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446274PMC
May 2017

The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity.

Invest Ophthalmol Vis Sci 2017 02;58(2):1296-1303

Department of Cardiovascular Sciences, Methodist Hospital System, Houston, Texas, United States.

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http://dx.doi.org/10.1167/iovs.16-20670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020715PMC
February 2017

Dynamic measures of skeletal muscle dialysate and plasma amino acid concentration in response to exercise and nutrient ingestion in healthy adult males.

Amino Acids 2017 01 4;49(1):151-159. Epub 2016 Oct 4.

Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland.

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http://dx.doi.org/10.1007/s00726-016-2343-8DOI Listing
January 2017

The use of machine learning for the identification of peripheral artery disease and future mortality risk.

J Vasc Surg 2016 Nov 3;64(5):1515-1522.e3. Epub 2016 Jun 3.

Division of Vascular Surgery, Stanford Health Care, Stanford, Calif. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079774PMC
http://dx.doi.org/10.1016/j.jvs.2016.04.026DOI Listing
November 2016

Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation.

Circ Res 2016 Oct 13;119(9):e129-e138. Epub 2016 Sep 13.

From the Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute, TX.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065398PMC
http://dx.doi.org/10.1161/CIRCRESAHA.116.308263DOI Listing
October 2016

LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration.

J Am Heart Assoc 2016 10 6;5(10). Epub 2016 Oct 6.

Center for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX

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http://dx.doi.org/10.1161/JAHA.116.004117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121509PMC
October 2016

Mechanisms of Atherosclerosis: New Insights and Novel Therapeutic Approaches.

Authors:
John P Cooke

Methodist Debakey Cardiovasc J 2015 Jul-Sep;11(3):154-5

Houston Methodist Research Institute, Houston, Texas.

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http://dx.doi.org/10.14797/mdcj-11-3-154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666420PMC
September 2016

New Insights Into Tobacco-Induced Vascular Disease: Clinical Ramifications.

Authors:
John P Cooke

Methodist Debakey Cardiovasc J 2015 Jul-Sep;11(3):156-9

Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas.

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http://dx.doi.org/10.14797/mdcj-11-3-156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666421PMC
September 2016

Telomerase Therapy to Reverse Cardiovascular Senescence.

Methodist Debakey Cardiovasc J 2015 Jul-Sep;11(3):172-5

Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas.

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http://dx.doi.org/10.14797/mdcj-11-3-172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666424PMC
September 2016

Therapeutic Transdifferentiation: A Novel Approach for Ischemic Syndromes.

Methodist Debakey Cardiovasc J 2015 Jul-Sep;11(3):176-80

Houston Methodist Research Institute, Houston, Texas.

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http://journal.houstonmethodist.org/doi/10.14797/mdcj-11-3-1
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http://dx.doi.org/10.14797/mdcj-11-3-176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666425PMC
September 2016

Erratum: Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA.

Cell Discov 2016 30;2:16032. Epub 2016 Aug 30.

Department of Cell Biology and Stem Cell Research Center, School of Basic Medical Sciences, Center for Molecular and Translational Medicine, Peking University Health Science Center, Beijing, China; The MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China; Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.

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http://dx.doi.org/10.1038/celldisc.2016.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004231PMC
September 2016

Nanotherapeutic Solutions for Cardiovascular Disease.

Methodist Debakey Cardiovasc J 2016 Sep;12(3):132-133

Houston Methodist Research Institute, Houston, Texas.

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http://dx.doi.org/10.14797/mdcj-12-3-132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098568PMC
September 2016

Enhancing Stent Effectiveness with Nanofeatures.

Methodist Debakey Cardiovasc J 2016 Sep;12(3):163-168

Northeastern University, Boston, Massachusetts.

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http://dx.doi.org/10.14797/mdcj-12-3-163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098574PMC
September 2016

Vascular Inflammation: A Novel Access Route for Nanomedicine.

Methodist Debakey Cardiovasc J 2016 Sep;12(3):169-174

Houston Methodist Research Institute, Houston, Texas; Houston Methodist Hospital, Houston, Texas.

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http://dx.doi.org/10.14797/mdcj-12-3-169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098575PMC
September 2016

Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA.

Cell Discov 2015 8;1:15040. Epub 2015 Dec 8.

Department of Cell Biology and Stem Cell Research Center, School of Basic Medical Sciences, Center for Molecular and Translational Medicine, Peking University Health Science Center, Beijing, China; The MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China; Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.

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http://www.nature.com/articles/celldisc201540
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http://dx.doi.org/10.1038/celldisc.2015.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860832PMC
July 2016

Erratum: Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA.

Cell Discov 2016 26;2:15052. Epub 2016 Jan 26.

Department of Cell Biology and Stem Cell Research Center, School of Basic Medical Sciences, Center for Molecular and Translational Medicine, Peking University Health Science Center, Beijing, China; The MOE Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China; Shenzhen Stem Cell Engineering Laboratory, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.

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http://dx.doi.org/10.1038/celldisc.2015.52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860956PMC
July 2016

How May Proton Pump Inhibitors Impair Cardiovascular Health?

Am J Cardiovasc Drugs 2016 Jun;16(3):153-61

Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s40256-016-0160-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864131PMC
June 2016

Proton Pump Inhibitors Accelerate Endothelial Senescence.

Circ Res 2016 06 10;118(12):e36-42. Epub 2016 May 10.

From the Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute, TX (G.Y., R.S., T.Z.N-.S., J.P.C.); Department of Chemical Physiology, Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA (M.P.); and Department of Radiation Oncology, Baylor College of Medicine, One Baylor Plaza, Houston, TX (Y.T.G.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902745PMC
June 2016

Optimal ROS Signaling Is Critical for Nuclear Reprogramming.

Cell Rep 2016 05 21;15(5):919-925. Epub 2016 Apr 21.

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute (HMRI), 6670 Bertner Avenue, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856580PMC
May 2016

Therapeutic transdifferentiation of human fibroblasts into endothelial cells using forced expression of lineage-specific transcription factors.

J Tissue Eng 2016 Jan-Dec;7:2041731416628329. Epub 2016 Feb 1.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.

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http://dx.doi.org/10.1177/2041731416628329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820020PMC
April 2016

Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat.

Am J Physiol Heart Circ Physiol 2016 Mar 22;310(6):H705-15. Epub 2016 Jan 22.

Vascular Biology and Hypertension Program, Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;

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http://dx.doi.org/10.1152/ajpheart.00587.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865064PMC
March 2016

Reply.

Gastroenterology 2016 Feb 22;150(2):528. Epub 2015 Dec 22.

Divisions of Cardiovascular Medicine and Vascular Surgery, Stanford University, Stanford, California.

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http://dx.doi.org/10.1053/j.gastro.2015.12.017DOI Listing
February 2016

Response to Letter Regarding Article "Transdifferentiation of Human Fibroblasts to Endothelial Cells: Role of Innate Immunity".

Circulation 2015 Oct;132(15):e197

Division of Biomedical Informatics Cincinnati Children's Hospital Medical Center Cincinnati, OH.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016792DOI Listing
October 2015

Proton pump inhibitors and vascular function: A prospective cross-over pilot study.

Vasc Med 2015 Aug 2;20(4):309-16. Epub 2015 Apr 2.

Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA

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http://dx.doi.org/10.1177/1358863X14568444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572842PMC
August 2015

Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.

FASEB J 2015 May 22;29(5):1930-9. Epub 2015 Jan 22.

*Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Clinical Sciences Research Center, Stanford University School of Medicine, Stanford, California, USA; Falk Cardiovascular Research Center, Stanford University School of Medicine, Stanford, California, USA; SpectraCell Laboratories, Inc., Houston, Texas, USA; and Department of Mechanical Engineering, Stanford University, Stanford, California, USA

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http://dx.doi.org/10.1096/fj.14-259531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415018PMC
May 2015

A compendium on peripheral arterial disease.

Circ Res 2015 Apr;116(9):1505-8

From the Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX (J.P.C.); and Division of Cardiology, University of California San Diego (Z.C.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410267PMC
April 2015

Modulating the vascular response to limb ischemia: angiogenic and cell therapies.

Circ Res 2015 Apr;116(9):1561-78

From the Department of Cardiovascular Sciences, Houston Methodist Research Institute, TX (J.P.C.); and NeoStem Inc, New York, NY (D.W.L.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869986PMC
http://dx.doi.org/10.1161/CIRCRESAHA.115.303565DOI Listing
April 2015

Effect of physical activity assessment on prognostication for peripheral artery disease and mortality.

Mayo Clin Proc 2015 Mar 31;90(3):339-45. Epub 2015 Jan 31.

Division of Vascular Surgery, Stanford University School of Medicine, Stanford, CA; Stanford Cardiovascular Institute, Stanford, CA. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2014.12.016DOI Listing
March 2015

Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity.

Circulation 2015 Jan 30;131(3):300-9. Epub 2014 Oct 30.

From the Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX (N.S., W.T.W., F.O., S.M., J.P.C.); Division of Cardiovascular Medicine, Stanford University, Stanford, CA (J.L., A.J.); and Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (P.D., B.J.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.007394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309381PMC
January 2015

Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial.

Circ Res 2015 Jan 18;116(1):99-107. Epub 2014 Nov 18.

From the Houston Methodist DeBakey Heart and Vascular Center (R.C.S., B.H.T., J.P.C.) and Houston Methodist Research Institute (R.C.S., B.H.T., J.P.C.), TX; Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, MN (J.H.T.); Cedars-Sinai Heart Institute, Los Angeles, CA (T.D.H.); University of Florida College of Medicine, Gainesville (C.J.P., C.R.C.); Texas Heart Institute, CHI St. Luke's Health, Houston (J.T.W., E.C.P., M.R., A.O., D.A.T.); University of Minnesota School of Medicine, Minneapolis (C.Z.); Cleveland Clinic Foundation, OH (S.G.E.); Wake Forest, School of Medicine, Winston-Salem, NC (D.X.M.Z.); University of Louisville, School of Medicine, KY (A.B.); Indiana University School of Medicine, Indianapolis (B.H.J.); The University of Texas Health Science Center, School of Public Health, Houston (D.L., S.L.S., L.M.); National Heart, Lung, and Blood Institute, Bethesda, MD (R.F.E.); Stanford University, School of Medicine, CA (J.C.W.); and Kansas University Medical Center, School of Medicine, Kansas City (R.D.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282599PMC
January 2015

Regenerative medicine in cardiovascular disease: introduction.

Methodist Debakey Cardiovasc J 2013 Oct-Dec;9(4):186

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846070PMC
http://dx.doi.org/10.14797/mdcj-9-4-186DOI Listing
December 2014

Clinical trials of adult stem cell therapy for peripheral artery disease.

Methodist Debakey Cardiovasc J 2013 Oct-Dec;9(4):201-5

Stanford University, Stanford, California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846073PMC
http://dx.doi.org/10.14797/mdcj-9-4-201DOI Listing
December 2014

Induced pluripotent stem cells: how they will change the practice of cardiovascular medicine.

Methodist Debakey Cardiovasc J 2013 Oct-Dec;9(4):206-9

Houston Methodist Hospital Research Institute, Houston Methodist Hospital, Houston, Texas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846074PMC
http://dx.doi.org/10.14797/mdcj-9-4-206DOI Listing
December 2014

Therapeutic transdifferentiation: can we generate cardiac tissue rather than scar after myocardial injury?

Methodist Debakey Cardiovasc J 2013 Oct-Dec;9(4):210-2

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846075PMC
http://dx.doi.org/10.14797/mdcj-9-4-210DOI Listing
December 2014

Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden.

PLoS One 2014 18;9(2):e88972. Epub 2014 Feb 18.

Division of Vascular Surgery, Stanford University School of Medicine, Stanford, California, United States of America ; Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088972PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928325PMC
October 2014

Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.

Circ Res 2014 Oct 18;115(10):867-74. Epub 2014 Aug 18.

From the University of Florida College of Medicine, Gainesville (C.R.C., E.W., A.M.M., M.B.G., R.C.B., E.W.S., C.J.P.); University of Minnesota School of Medicine, Minneapolis (C.Z., M.C.); Minneapolis Heart Institute Foundation at Abbott, MN (J.H.T., T.D.H., R.E.O.); Texas Heart Institute, Houston (E.C.P., J.T.W., M.d.G.C.-H., D.A.T.); Cleveland Clinic Foundation, OH (S.G.E.); Wake Forest Baptist Health, Winston-Salem, NC (D.X.M.Z.); University of Louisville, School of Medicine, KY (R.B., A.B.); Houston Methodist Research Institute, TX (J.P.C.); University of Pennsylvania School of Medicine, Philadelphia (S.A.); University of Texas School of Public Health, Houston (D.L., L.M., S.L.S.); National Heart, Lung and Blood Institute, Bethesda, MD (R.F.E.); University of Miami School of Medicine, FL (I.H.S.), and Mayo Clinic College of Medicine, Rochester, MN (R.D.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.304353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358751PMC
October 2014

Innate immunity and epigenetic plasticity in cellular reprogramming.

Curr Opin Genet Dev 2014 Oct;28:89-91

Center for Cardiovascular Regeneration, Houston Methodist Research Institute, United States.

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http://dx.doi.org/10.1016/j.gde.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262715PMC
October 2014

Clinical and socioeconomic factors associated with unrecognized peripheral artery disease.

Vasc Med 2014 Aug 28;19(4):289-296. Epub 2014 May 28.

Division of Vascular Surgery, Stanford University School of Medicine, Stanford, CA, USA Stanford Cardiovascular Institute, Stanford, CA, USA

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http://dx.doi.org/10.1177/1358863X14535475DOI Listing
August 2014

Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease.

Atherosclerosis 2014 Jul 28;235(1):94-101. Epub 2014 Apr 28.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102310PMC
July 2014

β2-microglobulin, cystatin C, and creatinine and risk of symptomatic peripheral artery disease.

J Am Heart Assoc 2014 Jun 30;3(4). Epub 2014 Jun 30.

Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA (M.M.J., M.L.B., K.J.M.).

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http://dx.doi.org/10.1161/JAHA.114.000803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310365PMC
June 2014

Near-infrared II fluorescence for imaging hindlimb vessel regeneration with dynamic tissue perfusion measurement.

Circ Cardiovasc Imaging 2014 May 21;7(3):517-25. Epub 2014 Mar 21.

From the School of Medicine, Division of Cardiovascular Medicine (J.C.L., A.J., J.P.C., N.F.H.), Department of Pediatrics (T.C.D.), Department of Chemistry (G.H., S.D., J.T.R., A.L.A., H.D.), and Cardiovascular Institute (K.H.N., L.H., H.D., J.P.C., N.F.H.), Stanford University, CA; and Veteran Affairs Palo Alto Health Care System, Palo Alto, CA (K.H.N., L.H., N.F.H.).

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079035/
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http://dx.doi.org/10.1161/CIRCIMAGING.113.000305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079035PMC
May 2014

Characterization of a fluorescent probe for imaging nitric oxide.

J Vasc Res 2014 11;51(1):68-79. Epub 2013 Dec 11.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, Tex., USA.

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http://dx.doi.org/10.1159/000356445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927988PMC
March 2014

Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.

Proc Natl Acad Sci U S A 2014 Feb 4;111(7):2698-703. Epub 2014 Feb 4.

Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Korea.

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http://dx.doi.org/10.1073/pnas.1320243111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932909PMC
February 2014

A novel and potent inhibitor of dimethylarginine dimethylaminohydrolase: a modulator of cardiovascular nitric oxide.

J Pharmacol Exp Ther 2014 Jan 17;348(1):69-76. Epub 2013 Oct 17.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, Texas (Y.T.G., J.P.C.); and SPARK Translational Research Program, Stanford University, School of Medicine, Stanford, California (D.A.E.).

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http://dx.doi.org/10.1124/jpet.113.206847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868884PMC
January 2014

Concurrent generation of functional smooth muscle and endothelial cells via a vascular progenitor.

Stem Cells Transl Med 2014 Jan 5;3(1):91-7. Epub 2013 Dec 5.

Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology, Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, and Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.5966/sctm.2013-0124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902294PMC
January 2014

Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow.

Biophys J 2014 Jan;106(2):366-74

Chemical Engineering, Stanford University, Stanford, California; Stanford Cardiovascular Institute, Stanford University, Stanford, Califiornia. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2013.11.4502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907231PMC
January 2014

Pharmacovigilance using Clinical Text.

AMIA Jt Summits Transl Sci Proc 2013 18;2013:109. Epub 2013 Mar 18.

Stanford University, Stanford, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814501PMC
December 2013

Alternative ankle-brachial index method identifies additional at-risk individuals.

J Am Coll Cardiol 2013 Aug 22;62(6):553-9. Epub 2013 May 22.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.jacc.2013.04.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732795PMC
August 2013

Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.

Circulation 2013 Aug 3;128(8):845-53. Epub 2013 Jul 3.

Department of Cardiovascular Sciences, Texas Methodist Hospital Research Institute, Houston, TX 77030, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838201PMC
August 2013

Chemotaxis of human induced pluripotent stem cell-derived endothelial cells.

Am J Transl Res 2013 15;5(5):510-20. Epub 2013 Aug 15.

Division of Cardiovascular Medicine, Stanford University 300 Pasteur Drive, Stanford, CA 94305-5406, USA ; Stanford Cardiovascular Institute, Stanford University 300 Pasteur Drive, Stanford, CA 94305, USA ; Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System 3801 Miranda Avenue, Palo Alto, CA 94304, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745438PMC
August 2013