John M Maris

John M Maris

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John M Maris

John M Maris

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Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.

Mol Cancer Ther 2019 Jul 9;18(7):1195-1204. Epub 2019 May 9.

Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606392PMC
July 2019

In Memoriam: Giulio D'Angio, MD, May 2, 1922-September 14, 2018.

Int J Radiat Oncol Biol Phys 2019 Jul;104(3):478-480

Pediatric Radiation Oncology, Dana Farber/Boston Children's Cancer and Blood Disorders Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.03.046DOI Listing
July 2019

Rare MYC-amplified Neuroblastoma With Large Cell Histology.

Pediatr Dev Pathol 2018 Sep-Oct;21(5):461-466. Epub 2018 Feb 9.

1 Department of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1177/1093526617749670DOI Listing
June 2019

Outcomes After Proton Therapy for Treatment of Pediatric High-Risk Neuroblastoma.

Int J Radiat Oncol Biol Phys 2019 Jun 7;104(2):401-408. Epub 2019 Feb 7.

Department of Pediatrics, Division of Oncology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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https://linkinghub.elsevier.com/retrieve/pii/S03603016193019
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http://dx.doi.org/10.1016/j.ijrobp.2019.01.095DOI Listing
June 2019

Dr. Giulio J. D'Angio (1922-2018).

Pediatr Res 2019 May 7;85(6):752-753. Epub 2019 Feb 7.

Giulio D'Angio Professor of Pediatric Oncology Perelman School of Medicine, Division of Oncology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.1038/s41390-019-0328-5DOI Listing
May 2019

Giulio (Dan) J. D'Angio, MD (1922-2018).

Pediatr Radiol 2019 May 19;49(6):837-838. Epub 2019 Apr 19.

Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, 3400 Civic Center Blvd., Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00247-019-04399-0DOI Listing
May 2019

The challenge of defining "ultra-high-risk" neuroblastoma.

Pediatr Blood Cancer 2019 Apr 26;66(4):e27556. Epub 2018 Nov 26.

Hospital for Sick Children and University of Toronto, Toronto, Canada.

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http://doi.wiley.com/10.1002/pbc.27556
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http://dx.doi.org/10.1002/pbc.27556DOI Listing
April 2019

Differences in Genomic Profiles and Outcomes between Thoracic and Adrenal Neuroblastoma.

J Natl Cancer Inst 2019 Feb 21. Epub 2019 Feb 21.

Department of Pediatrics, Childrens Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1093/jnci/djz027DOI Listing
February 2019

Giulio J. D'Angio, MD, 1922-2018.

Pediatr Blood Cancer 2019 Jan 23;66(1):e27508. Epub 2018 Oct 23.

University, of Padua, Padua, Italy.

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http://dx.doi.org/10.1002/pbc.27508DOI Listing
January 2019

Transverse myelitis as an unexpected complication following treatment with dinutuximab in pediatric patients with high-risk neuroblastoma: A case series.

Pediatr Blood Cancer 2018 Jan 27;65(1). Epub 2017 Jul 27.

Departments of Pediatric Heamtology and Oncology and radiology, Hospital Sant Joan de Deu, Barcelona, Spain.

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http://dx.doi.org/10.1002/pbc.26732DOI Listing
January 2018

Differential killing of CD56-expressing cells by drug-conjugated human antibodies targeting membrane-distal and membrane-proximal non-overlapping epitopes.

MAbs 2016 May-Jun;8(4):799-810. Epub 2016 Feb 24.

a Protein Interactions Section, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute , Frederick , MD , USA.

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http://dx.doi.org/10.1080/19420862.2016.1155014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966860PMC
November 2017

Comprehensive Analysis of Hypermutation in Human Cancer.

Cell 2017 Nov 19;171(5):1042-1056.e10. Epub 2017 Oct 19.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849393PMC
November 2017

Evaluation of Genetic Predisposition for MYCN-Amplified Neuroblastoma.

J Natl Cancer Inst 2017 10;109(10)

Affiliations of authors: Section of Hematology/Oncology, Department of Pediatrics (EAH, MAA, ADS, SLV, SLC), Section of Genetic Medicine, Department of Medicine (BES), and Institute for Genomics and Systems Biology, Center for Data Intensive Science (BES), University of Chicago, Chicago, IL; Division of Oncology and Center for Childhood Cancer Research and Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA (ZV, MD, LM, JMM, SJD); Department of Pediatrics and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (JMM, SJD); Department of Pediatrics, Hofstra-Northwell School of Medicine and The Feinstein Institute for Medical Research, Manhasset, NY (KO).

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http://dx.doi.org/10.1093/jnci/djx093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279278PMC
October 2017

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Cancer Cell 2017 09;32(3):295-309.e12

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600520PMC
September 2017

Revisions to the International Neuroblastoma Response Criteria: A Consensus Statement From the National Cancer Institute Clinical Trials Planning Meeting.

J Clin Oncol 2017 Aug 4;35(22):2580-2587. Epub 2017 May 4.

Julie R. Park, Seattle Children's Hospital and University of Washington School of Medicine, Seattle, WA; Rochelle Bagatell and John M. Maris, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA; Susan L. Cohn, University of Chicago, Chicago, IL; Andrew D. Pearson, Institute of Cancer Research and Royal Marsden National Health Service (NHS) Foundation Trust, Sutton, Surrey; Susan Burchill, Leeds Institute of Cancer and Pathology, St James University Hospital, Leeds; Kieran McHugh and Penelope Brock, Great Ormond Street Hospital for Children, NHS Trust, London, United Kingdom; Judith G. Villablanca, Children's Hospital Los Angeles and University of Southern California Keck School of Medicine, Los Angeles; Katherine K. Matthay, University of California San Francisco School of Medicine, San Francisco, CA; Frank Berthold, Children's Hospital and University of Cologne, Köln, Germany; Ariane Boubaker, Institute of Radiology, Clinique de La Source, Lausanne, Switzerland; Jed G. Nuchtern, Texas Children's Hospital and Baylor College of Medicine, Houston, TX; Wendy B. London, Dana-Farber/Boston Children's Cancer and Blood Disorder Center, Harvard Medical School, Boston, MA; Nita L. Seibel and O. Wolf Lindwasser, National Cancer Institute, Bethesda, MD; Gudrun Schleiermacher, Institut Curie, Paris; Dominique Valteau-Couanet, Gustave Roussy, Villejuif, France; and Ruth Ladenstein, Children's Cancer Research Institute, St Anna Children's Hospital, Vienna, Austria.

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http://dx.doi.org/10.1200/JCO.2016.72.0177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676955PMC
August 2017

11q deletion in neuroblastoma: a review of biological and clinical implications.

Mol Cancer 2017 06 29;16(1):114. Epub 2017 Jun 29.

CANSEARCH Research Laboratory, Geneva University Medical School, Avenue de la Roseraie 64, 1205, Geneva, Switzerland.

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http://dx.doi.org/10.1186/s12943-017-0686-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492892PMC
June 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

Dexmedetomidine does not interfere with meta-iodobenzylguanidine (MIBG) uptake at clinically relevant concentrations.

Pediatr Blood Cancer 2017 04 22;64(4). Epub 2016 Sep 22.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.26268DOI Listing
April 2017

Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma.

Clin Cancer Res 2017 Apr 11;23(7):1785-1796. Epub 2016 Oct 11.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1131DOI Listing
April 2017

Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.

Sci Data 2017 03 28;4:170033. Epub 2017 Mar 28.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/sdata.2017.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369315PMC
March 2017

Genetic susceptibility to neuroblastoma.

Curr Opin Genet Dev 2017 Feb 28;42:81-90. Epub 2017 Apr 28.

University of Pennsylvania, United States; Children's Hospital of Philadelphia, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2017.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604862PMC
February 2017

Neuroblastoma.

Nat Rev Dis Primers 2016 11 10;2:16078. Epub 2016 Nov 10.

Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nrdp.2016.78DOI Listing
November 2016

A family-based study of gene variants and maternal folate and choline in neuroblastoma: a report from the Children's Oncology Group.

Cancer Causes Control 2016 10 19;27(10):1209-18. Epub 2016 Aug 19.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Campus Box 7435, 2106 McGavran-Greenberg Hall, Chapel Hill, NC, 27599-7435, USA.

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http://dx.doi.org/10.1007/s10552-016-0799-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025391PMC
October 2016

Incidence and risk factors for secondary malignancy in patients with neuroblastoma after treatment with (131)I-metaiodobenzylguanidine.

Eur J Cancer 2016 10 27;66:144-52. Epub 2016 Aug 27.

Department of Pediatrics, University of California San Francisco Benioff Children's Hospital, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.07.017DOI Listing
October 2016

Imaging genomics in cancer research: limitations and promises.

Br J Radiol 2016 11;89(1061):20151030. Epub 2016 Feb 11.

4 Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1259/bjr.20151030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985482PMC
September 2016

Phase I Study of the Aurora A Kinase Inhibitor Alisertib in Combination With Irinotecan and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma: A NANT (New Approaches to Neuroblastoma Therapy) Trial.

J Clin Oncol 2016 Apr 16;34(12):1368-75. Epub 2016 Feb 16.

Steven G. DuBois, Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA; Araz Marachelian, Susan Groshen, Jemily Malvar, Hollie Lai, Fariba Goodarzian, Hiroyuki Shimada, Scarlett Czarnecki, and Denice Tsao-Wei, University of Southern California Keck School of Medicine and Children's Hospital Los Angeles, Los Angeles; Randall Hawkins, Jesse Courtier, and Katherine K. Matthay, University of California, San Francisco, School of Medicine and Benioff Children's Hospital, San Francisco, CA; Elizabeth Fox, Rochelle Bagatell, John M. Maris, and Yael P. Mosse, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Rachel A. Kudgus and Joel M. Reid, Mayo Clinic, Rochester, MN; and Lars Wagner, University of Kentucky College of Medicine, Lexington, KY.

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http://jco.ascopubs.org/content/early/2016/02/11/JCO.2015.65
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.65.4889
Publisher Site
http://dx.doi.org/10.1200/JCO.2015.65.4889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872349PMC
April 2016

Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations.

Cancer 2016 Jan 5;122(1):20-33. Epub 2015 Nov 5.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.29706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707066PMC
January 2016

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

Cell Metab 2015 Dec 17;22(6):1009-19. Epub 2015 Sep 17.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818967PMC
December 2015

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.

Cancer Discov 2015 Dec 29;5(12):1282-95. Epub 2015 Oct 29.

Division of Cancer Pathobiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Immunology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Cell & Molecular Biology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Department of Pathology & Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-15-1020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670800PMC
December 2015

Defining Why Cancer Develops in Children.

Authors:
John M Maris

N Engl J Med 2015 Dec 18;373(24):2373-5. Epub 2015 Nov 18.

From the Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and the Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania - both in Philadelphia.

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http://dx.doi.org/10.1056/NEJMe1513921DOI Listing
December 2015

Treatment of neuroblastoma in congenital central hypoventilation syndrome with a PHOX2B polyalanine repeat expansion mutation: New twist on a neurocristopathy syndrome.

Pediatr Blood Cancer 2015 Nov 22;62(11):2007-10. Epub 2015 May 22.

Division of Hematology, Oncology & Transplantation, Robert Lurie Comprehensive Cancer Center, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://doi.wiley.com/10.1002/pbc.25572
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http://dx.doi.org/10.1002/pbc.25572DOI Listing
November 2015

A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis.

Cancer Cell 2015 Nov 17;28(5):599-609. Epub 2015 Oct 17.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643330PMC
November 2015

Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma.

Pediatr Blood Cancer 2015 Oct 7;62(10):1739-46. Epub 2015 Jul 7.

Cancer Center and Departments of Cell Biology & Biochemistry, Pediatrics and Medicine, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.

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http://dx.doi.org/10.1002/pbc.25594DOI Listing
October 2015

Improving Patient Outcomes With Cancer Genomics: Unique Opportunities and Challenges in Pediatric Oncology.

JAMA 2015 Sep;314(9):881-3

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania2Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1001/jama.2015.9794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599710PMC
September 2015

G-CSF Is a Cancer Stem Cell-Specific Growth Factor-Letter.

Cancer Res 2015 Sep 3;75(18):3991. Epub 2015 Sep 3.

Department Studies and Statistics, Children's Cancer Research Institute, Vienna, Austria.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1445DOI Listing
September 2015

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus.

Cancer Res 2015 Aug 22;75(15):3155-66. Epub 2015 Jun 22.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. The Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526355PMC
August 2015

Identifying rare events in rare diseases.

Clin Cancer Res 2015 Apr 25;21(8):1782-5. Epub 2014 Nov 25.

Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2314DOI Listing
April 2015

Age-dependent prognostic effect by Mitosis-Karyorrhexis Index in neuroblastoma: a report from the Children's Oncology Group.

Pediatr Dev Pathol 2014 Nov-Dec;17(6):441-9. Epub 2014 Sep 10.

1 Department of Pathology & Laboratory Medicine, Children's Hospital Los Angeles, and University of Southern California Keck School of Medicine, 4650 Sunset Boulevard, MS #43, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.2350/14-06-1505-OA.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340697PMC
March 2015

Revisiting tissue specificity of germline cancer predisposing mutations.

Nat Rev Cancer 2015 02;15(2):65-6

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February 2015

Common genetic variants in NEFL influence gene expression and neuroblastoma risk.

Cancer Res 2014 Dec 13;74(23):6913-24. Epub 2014 Oct 13.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Genomics and Computational Biology, Biomedical Graduate Studies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253722PMC
December 2014

Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.

Cancer Chemother Pharmacol 2014 Nov 12;74(5):1047-55. Epub 2014 Sep 12.

Division of Oncology, The Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, CTRB 4020, Philadelphia, PA, 19104, USA,

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http://link.springer.com/content/pdf/10.1007/s00280-014-2575
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http://dx.doi.org/10.1007/s00280-014-2575-9DOI Listing
November 2014

The promises and pitfalls of genetic epidemiologic approaches to pediatric cancers: lessons from MDM2.

Pediatr Blood Cancer 2014 Oct 17;61(10):1717-8. Epub 2014 Jun 17.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Abramson Family Cancer Research Institute, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.25051DOI Listing
October 2014

The ASPHO 2014 distinguished career award goes to Dr. Beverly Lange.

Pediatr Blood Cancer 2014 May;61 Suppl 1:A1-2

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.25066DOI Listing
May 2014

Rare variants in TP53 and susceptibility to neuroblastoma.

J Natl Cancer Inst 2014 Apr 14;106(4):dju047. Epub 2014 Mar 14.

Affiliations of authors: Division of Oncology (SJD, MDi, DAO, KC, KRB, MRR, JMM), Center for Childhood Cancer Research (SJD, MDi, DAO, KC, KRB, MRR, JMM), Center for Applied Genomics (HH), and Division of Genetics (HH, MDe) Children's Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics (SJD, DAO, KRB, HH, MDe, JMM), Abramson Cancer Center (SJD, JMM), Genomics and Computational Biology, Biomedical Graduate Studies (SJD, DAO, JMM), and Department of Biostatistics and Epidemiology (MDe), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (SJD, HH, MDe, JMM); Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy (MC, AI); Ceinge-Biotecnologie Avanzate, Naples, Italy (MC, AI); University of Rome "La Sapienza," Department of Molecular Medicine, Rome, Italy (MDe).

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http://jnci.oxfordjournals.org/content/early/2014/03/14/jnci
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/dju047
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982892PMC
April 2014