John M Abrams

John M Abrams

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John M Abrams

John M Abrams

Publications by authors named "John M Abrams"

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p53 directs nonapoptotic programs in postmitotic tissue.

Mol Biol Cell 2019 05 20;30(11):1339-1351. Epub 2019 Mar 20.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.

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http://dx.doi.org/10.1091/mbc.E18-12-0791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724604PMC
May 2019

Transposons, p53 and Genome Security.

Trends Genet 2018 11 5;34(11):846-855. Epub 2018 Sep 5.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2018.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260979PMC
November 2018

Meeting report: mobile genetic elements and genome plasticity 2018.

Mob DNA 2018 22;9:21. Epub 2018 Jun 22.

9Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 USA.

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http://dx.doi.org/10.1186/s13100-018-0126-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015446PMC
June 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance.

Curr Biol 2017 Oct 28;27(19):3010-3016.e3. Epub 2017 Sep 28.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.08.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639916PMC
October 2017

p53 in the game of transposons.

Bioessays 2016 11 19;38(11):1111-1116. Epub 2016 Sep 19.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1002/bies.201600115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142446PMC
November 2016

Genome-wide association analysis of radiation resistance in Drosophila melanogaster.

PLoS One 2014 14;9(8):e104858. Epub 2014 Aug 14.

Department of Cell Biology, UT Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104858PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133248PMC
March 2016

p53 genes function to restrain mobile elements.

Genes Dev 2016 Jan 23;30(1):64-77. Epub 2015 Dec 23.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA;

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http://dx.doi.org/10.1101/gad.266098.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701979PMC
January 2016

Hid arbitrates collective cell death in the Drosophila wing.

Mech Dev 2015 Nov 29;138 Pt 3:349-55. Epub 2015 Jul 29.

Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75390-9039, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mod.2015.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679717PMC
November 2015

Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.

Cell Rep 2015 Feb 19;10(7):1096-109. Epub 2015 Feb 19.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365998PMC
February 2015

DNA loops specify p53 network responses.

Cell Cycle 2014 8;13(11):1659. Epub 2014 May 8.

Department of Cell Biology; UT Southwestern Medical Center; Dallas, TX USA.

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http://dx.doi.org/10.4161/cc.29149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111709PMC
January 2015

p53 activity is selectively licensed in the Drosophila stem cell compartment.

Elife 2014 Mar 11;3:e01530. Epub 2014 Mar 11.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949305PMC
http://dx.doi.org/10.7554/eLife.01530DOI Listing
March 2014

A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans.

Genes Dev 2013 Nov;27(22):2433-8

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1101/gad.225565.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841732PMC
November 2013

Tango7 directs cellular remodeling by the Drosophila apoptosome.

Genes Dev 2013 Aug;27(15):1650-5

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA

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http://dx.doi.org/10.1101/gad.219287.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744723PMC
August 2013

A cell-based screening platform identifies novel mosquitocidal toxins.

J Biomol Screen 2013 Jul 13;18(6):688-94. Epub 2013 Feb 13.

University of Texas Southwestern Medical Center, Department of Cell Biology, Dallas, TX, USA.

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http://dx.doi.org/10.1177/1087057113476952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687004PMC
July 2013

Meiotic recombination provokes functional activation of the p53 regulatory network.

Science 2010 Jun;328(5983):1278-81

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1126/science.1185640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917750PMC
June 2010

p53 ancestry: gazing through an evolutionary lens.

Nat Rev Cancer 2009 10;9(10):758-62

Wan-Jin Lu and John M. Abrams are at the Department of Cell Biology, University of Texas, Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nrc2732DOI Listing
October 2009

Genome-wide silencing in Drosophila captures conserved apoptotic effectors.

Nature 2009 Jul 31;460(7251):123-7. Epub 2009 May 31.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nature08087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777527PMC
July 2009

The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death.

Development 2009 Jan 15;136(2):275-83. Epub 2008 Dec 15.

Department of Cell Biology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9039, USA.

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http://dx.doi.org/10.1242/dev.019042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685970PMC
January 2009

The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death.

Development 2009 Jan 15;136(2):275-83. Epub 2008 Dec 15.

Department of Cell Biology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9039, USA.

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http://dx.doi.org/10.1242/dev.019042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685970PMC
January 2009

Noncanonical cell death pathways act during Drosophila oogenesis.

Genesis 2007 Jun;45(6):396-404

Department of Biology, Boston University, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1002/dvg.20306DOI Listing
June 2007

Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death.

Development 2006 Apr 15;133(8):1457-65. Epub 2006 Mar 15.

Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.02332
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http://dx.doi.org/10.1242/dev.02332DOI Listing
April 2006

Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span.

Curr Biol 2005 Nov;15(22):2063-8

University of Connecticut Health Center, Department of Genetics and Developmental Biology, 263 Farmington Avenue, Farmington, Connecticut 06073, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096098220501304
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http://dx.doi.org/10.1016/j.cub.2005.10.051DOI Listing
November 2005

Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.

Hum Mol Genet 2005 Feb 8;14(3):357-72. Epub 2004 Dec 8.

Neurogenetics Program, Department of Neurology, Neuropsychiatric Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://academic.oup.com/hmg/article/14/3/357/746521/Inactiva
Publisher Site
http://dx.doi.org/10.1093/hmg/ddi032DOI Listing
February 2005

Coordination of cell death and the cell cycle: linking proliferation to death through private and communal couplers.

Curr Opin Cell Biol 2004 Dec;16(6):634-8

Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9039, USA.

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http://dx.doi.org/10.1016/j.ceb.2004.09.010DOI Listing
December 2004

Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies.

Oncogene 2004 Apr;23(16):2774-84

Program in Apoptosis and Cell Death Research, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92122, USA.

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http://dx.doi.org/10.1038/sj.onc.1207522DOI Listing
April 2004

Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila.

Oncogene 2003 Jul;22(31):4860-7

Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75390-8593, USA.

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http://dx.doi.org/10.1038/sj.onc.1206715DOI Listing
July 2003

Drosophila p53 preserves genomic stability by regulating cell death.

Proc Natl Acad Sci U S A 2003 Apr 2;100(8):4696-701. Epub 2003 Apr 2.

Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9039, USA.

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http://dx.doi.org/10.1073/pnas.0736384100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153618PMC
April 2003

Competition and compensation: coupled to death in development and cancer.

Authors:
John M Abrams

Cell 2002 Aug;110(4):403-6

Department of Cell Biology, University of Texas Southwestern Medical Center, 75390, USA.

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http://dx.doi.org/10.1016/s0092-8674(02)00904-2DOI Listing
August 2002

Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark.

EMBO J 2002 May;21(9):2189-97

Department of Cell Biology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9039, USA.

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http://dx.doi.org/10.1093/emboj/21.9.2189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125994PMC
May 2002

The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

Curr Biol 2002 Jan;12(2):137-40

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9039, USA.

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http://dx.doi.org/10.1016/s0960-9822(01)00658-3DOI Listing
January 2002