Publications by authors named "John L Rubenstein"

99Publications

A Chromatin Accessibility Atlas of the Developing Human Telencephalon.

Cell 2020 Aug 30;182(3):754-769.e18. Epub 2020 Jun 30.

Department of Psychiatry, Langley Porter Psychiatric Institute, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415678PMC
August 2020

LacZ-reporter mapping of Dlx5/6 expression and genoarchitectural analysis of the postnatal mouse prethalamus.

J Comp Neurol 2020 May 18. Epub 2020 May 18.

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, UCSF Medical School, San Francisco, California, USA.

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http://dx.doi.org/10.1002/cne.24952DOI Listing
May 2020

Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants.

Cell Rep 2020 Apr;31(2):107495

Department of Psychiatry and UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.03.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473600PMC
April 2020

deletion results in depletion of the transcription factor and a specific loss of parvalbumin cortical interneurons.

Proc Natl Acad Sci U S A 2020 03 2;117(11):6189-6195. Epub 2020 Mar 2.

Department of Pediatrics and Human Development, Michigan State University, Grand Rapids, MI 49503;

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http://dx.doi.org/10.1073/pnas.1915458117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084085PMC
March 2020

Functionally Distinct Connectivity of Developmentally Targeted Striosome Neurons.

Cell Rep 2019 11;29(6):1419-1428.e5

Neuroscience Graduate Program, UCSF, San Francisco, CA 94158, USA; Weill Institute for Neurosciences, UCSF, San Francisco, CA 94158, USA; Kavli Institute for Fundamental Neuroscience, UCSF, San Francisco, CA 94158, USA; Department of Neurology, UCSF, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.09.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866662PMC
November 2019

Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons.

Cell Rep 2019 08;28(8):2048-2063.e8

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Development and Stem Cell Biology Program, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750766PMC
August 2019

Immature excitatory neurons develop during adolescence in the human amygdala.

Nat Commun 2019 06 21;10(1):2748. Epub 2019 Jun 21.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1038/s41467-019-10765-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588589PMC
June 2019

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders.

Mol Psychiatry 2019 09 14;24(9):1248-1257. Epub 2019 May 14.

Department of Psychiatry, Weill Institute for Neurosciences, and Kavli Institute for Fundamental Neuroscience, University of California San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1038/s41380-019-0426-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742424PMC
September 2019

Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.

Cereb Cortex 2019 12;29(11):4831-4849

State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, MOE Frontier Research Center for Brain Science, Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, PR China.

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http://dx.doi.org/10.1093/cercor/bhz018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917526PMC
December 2019

Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function.

Cell Rep 2019 01;26(5):1157-1173.e5

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602795PMC
January 2019

Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity.

Neuron 2018 11 11;100(4):831-845.e7. Epub 2018 Oct 11.

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273183082
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http://dx.doi.org/10.1016/j.neuron.2018.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250594PMC
November 2018

Genomic analysis of transcriptional networks directing progression of cell states during MGE development.

Neural Dev 2018 09 14;13(1):21. Epub 2018 Sep 14.

Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1186/s13064-018-0119-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138899PMC
September 2018

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

Front Neurosci 2018 22;12:571. Epub 2018 Aug 22.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.

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http://dx.doi.org/10.3389/fnins.2018.00571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113890PMC
August 2018

SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating expression.

Development 2018 07 23;145(14). Epub 2018 Jul 23.

State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China

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http://dx.doi.org/10.1242/dev.165456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078334PMC
July 2018

Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development.

Cereb Cortex 2019 06;29(6):2653-2667

State Key Laboratory of Medical Neurobiology, Department of Neurology, Institutes of Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1093/cercor/bhy133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519701PMC
June 2019

Ultraconserved Enhancers Are Required for Normal Development.

Cell 2018 01 18;172(3):491-499.e15. Epub 2018 Jan 18.

Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA; U.S. Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA; School of Natural Sciences, University of California Merced, Merced, CA 95343, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786478PMC
January 2018

Cortical interneuron development: a tale of time and space.

Development 2017 11;144(21):3867-3878

Department of Psychiatry, University of California, San Francisco, CA 94158, USA

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http://dx.doi.org/10.1242/dev.132852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702067PMC
November 2017

Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis.

Cereb Cortex 2018 11;28(11):3797-3815

Department of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/cercor/bhx241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188538PMC
November 2018

Mouse Cntnap2 and Human CNTNAP2 ASD Alleles Cell Autonomously Regulate PV+ Cortical Interneurons.

Cereb Cortex 2018 11;28(11):3868-3879

Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/cercor/bhx248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455910PMC
November 2018

Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development.

Cereb Cortex 2018 09;28(9):3278-3294

Department of Translational Neuroscience, Shanghai Pudong Hospital, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, and Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1093/cercor/bhx199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095218PMC
September 2018

and control subtype and laminar identity of MGE-derived neocortical interneurons.

Development 2017 08 10;144(15):2837-2851. Epub 2017 Jul 10.

Department of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA 94158, USA

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http://dx.doi.org/10.1242/dev.150664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560044PMC
August 2017

Generation of pure GABAergic neurons by transcription factor programming.

Nat Methods 2017 Jun 15;14(6):621-628. Epub 2017 May 15.

Institute for Stem Cell Biology and Regenerative Medicine and Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.4291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567689PMC
June 2017

Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.

Sci Rep 2017 03 31;7:45656. Epub 2017 Mar 31.

Department of Molecular Biology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1038/srep45656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374502PMC
March 2017

Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum.

Cell Rep 2016 10;17(3):735-747

Queensland Brain Institute, The University of Queensland, St. Lucia, QLD 4072, Australia; The School of Biomedical Sciences, The University of Queensland, St. Lucia, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094913PMC
October 2016

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.

Neuron 2016 Sep;91(6):1260-1275

Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319854PMC
September 2016

The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex.

Cereb Cortex 2017 09;27(9):4303-4313

Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1093/cercor/bhw230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410508PMC
September 2017

The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons.

Cell Rep 2016 08 21;16(5):1431-1444. Epub 2016 Jul 21.

Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972643PMC
August 2016

TBR1 regulates autism risk genes in the developing neocortex.

Genome Res 2016 08 20;26(8):1013-22. Epub 2016 Jun 20.

Department of Computer Science, Stanford University, Stanford, California 94305, USA; Department of Developmental Biology, Stanford University, Stanford, California 94305, USA; Division of Medical Genetics, Department of Pediatrics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1101/gr.203612.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971772PMC
August 2016

Radial derivatives of the mouse ventral pallium traced with Dbx1-LacZ reporters.

J Chem Neuroanat 2016 09 31;75(Pt A):2-19. Epub 2015 Dec 31.

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, University of California at San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.jchemneu.2015.10.011DOI Listing
September 2016

Accelerated Evolution of Enhancer Hotspots in the Mammal Ancestor.

Mol Biol Evol 2016 Apr 29;33(4):1008-18. Epub 2015 Dec 29.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA Department of Epidemiology and Biostatistics, University of California, San Francisco, CA Institute for Human Genetics, University of California, San Francisco, CA

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http://dx.doi.org/10.1093/molbev/msv344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776709PMC
April 2016

Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis.

Dev Cell 2015 Dec;35(6):713-24

Department of Orofacial Sciences and Program in Craniofacial Biology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA; Department of Pediatrics and Institute for Human Genetics, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710359PMC
December 2015

Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.

Neuron 2015 Dec 6;88(6):1192-1207. Epub 2015 Dec 6.

Department of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.10.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688141PMC
December 2015

EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex.

Development 2015 Nov;142(21):3746-57

The University of Queensland, Queensland Brain Institute, Brisbane 4072, Australia The University of Queensland, The School of Biomedical Sciences, Brisbane 4072, Australia

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http://dx.doi.org/10.1242/dev.119909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647209PMC
November 2015

Fgf15 regulates thalamic development by controlling the expression of proneural genes.

Brain Struct Funct 2016 07 27;221(6):3095-109. Epub 2015 Aug 27.

Instituto Murciano de Investigación Biosanitaria (IMIB-Arrixaca), University of Murcia, 30120, El Palmar, Murcia, Spain.

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http://dx.doi.org/10.1007/s00429-015-1089-5DOI Listing
July 2016

Transcriptional and epigenetic mechanisms of early cortical development: An examination of how Pax6 coordinates cortical development.

J Comp Neurol 2016 Feb 25;524(3):609-29. Epub 2015 Aug 25.

Department of Psychiatry, Neuroscience Program, and the Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1002/cne.23866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706819PMC
February 2016

miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.

Cell Rep 2015 Aug 23;12(5):760-73. Epub 2015 Jul 23.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Urology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741278PMC
August 2015

OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum.

Cell Rep 2015 Jul 9;12(3):482-94. Epub 2015 Jul 9.

Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512845PMC
July 2015

Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2.

Hum Mol Genet 2015 Sep 12;24(17):5024-39. Epub 2015 Jun 12.

Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY 10010, USA,

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddv223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527495PMC
September 2015

Cux2-positive radial glial cells generate diverse subtypes of neocortical projection neurons and macroglia.

Neuron 2015 May;86(4):1100-1108

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441766PMC
May 2015

Molecular codes defining rostrocaudal domains in the embryonic mouse hypothalamus.

Front Neuroanat 2015 17;9:46. Epub 2015 Apr 17.

Department of Psychiatry, Rock Hall, University of California San Francisco, CA, USA.

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http://dx.doi.org/10.3389/fnana.2015.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400913PMC
May 2015

The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles.

Cell Rep 2015 May 30;11(6):944-956. Epub 2015 Apr 30.

Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Program, University of California, San Francisco, San Francisco, CA 94158, USA; Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431948PMC
May 2015

Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center.

Neural Dev 2015 Mar 31;10. Epub 2015 Mar 31.

Department of Psychiatry, University of California, 1550 4th Street, UCSF MC 2611, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s13064-015-0037-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416298PMC
March 2015

A new scenario of hypothalamic organization: rationale of new hypotheses introduced in the updated prosomeric model.

Front Neuroanat 2015 19;9:27. Epub 2015 Mar 19.

Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, University of California, San Francisco San Francisco, CA, USA.

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http://dx.doi.org/10.3389/fnana.2015.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365718PMC
April 2015

Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity.

Pain 2015 Jun;156(6):1084-91

Departments of aAnatomy bAnesthesia and Critical Care cDepartment of Psychiatry, The Nina Ireland Laboratory Developmental Neurobiology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1097/j.pain.0000000000000152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431911PMC
June 2015

Gamma rhythms link prefrontal interneuron dysfunction with cognitive inflexibility in Dlx5/6(+/-) mice.

Neuron 2015 Mar 5;85(6):1332-43. Epub 2015 Mar 5.

Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA; Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA 94143, USA; Sloan-Swartz Center for Theoretical Neurobiology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503262PMC
March 2015

Genomic perspectives of transcriptional regulation in forebrain development.

Neuron 2015 Jan;85(1):27-47

Department of Psychiatry, Rock Hall, University of California, San Francisco, San Francisco, CA 94158-2324, USA.

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http://dx.doi.org/10.1016/j.neuron.2014.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438709PMC
January 2015

An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females.

Cell Rep 2015 Jan 24;10(1):62-74. Epub 2014 Dec 24.

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324838PMC
January 2015

NPAS1 represses the generation of specific subtypes of cortical interneurons.

Neuron 2014 Dec 20;84(5):940-53. Epub 2014 Nov 20.

Department of Psychiatry, Neuroscience Program, and the Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco, San Francisco, CA 94158-2324, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258152PMC
December 2014

A class of GABAergic neurons in the prefrontal cortex sends long-range projections to the nucleus accumbens and elicits acute avoidance behavior.

J Neurosci 2014 Aug;34(35):11519-25

Department of Psychiatry, Center for Integrative Neuroscience, and Sloan-Swartz Center for Theoretical Neurobiology, University of California, San Francisco, San Francisco, California 94143-0444

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http://dx.doi.org/10.1523/JNEUROSCI.1157-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145166PMC
August 2014

Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex.

Neuron 2014 Jun 8;82(5):989-1003. Epub 2014 May 8.

Department of Psychiatry, Program in Neuroscience, Rock Hall, University of California at San Francisco, San Francisco, CA 94158-2324, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104757PMC
June 2014

Major progress towards elucidating brain wiring diagrams.

J Comp Neurol 2014 Jun;522(9):1987-8

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http://dx.doi.org/10.1002/cne.23586DOI Listing
June 2014

Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position.

Neuron 2014 Apr;82(2):350-64

Department of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261952PMC
April 2014

Interneurons from embryonic development to cell-based therapy.

Science 2014 Apr;344(6180):1240622

Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/science.1240622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056344PMC
April 2014

Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex.

Neural Dev 2014 Mar 12;9. Epub 2014 Mar 12.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA, USA.

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http://dx.doi.org/10.1186/1749-8104-9-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008173PMC
March 2014

Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.

Neuron 2014 Feb;81(3):574-87

Department of Pediatrics, Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2013.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979971PMC
February 2014

Pyramidal neurons in prefrontal cortex receive subtype-specific forms of excitation and inhibition.

Neuron 2014 Jan 19;81(1):61-8. Epub 2013 Dec 19.

Department of Psychiatry, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94143-0444, USA; Center for Integrative Neuroscience, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94143-0444, USA; Sloan-Swartz Center for Theoretical Neurobiology, University of California, San Francisco, 675 Nelson Rising Lane, San Francisco, CA 94143-0444, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2013.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947199PMC
January 2014

Rapid and pervasive changes in genome-wide enhancer usage during mammalian development.

Cell 2013 Dec;155(7):1521-31

Genomics Division, MS 84-171, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; U.S. Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA; School of Natural Sciences, University of California, Merced, CA 95343, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.11.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989111PMC
December 2013

Bidirectional homeostatic plasticity induced by interneuron cell death and transplantation in vivo.

Proc Natl Acad Sci U S A 2014 Jan 16;111(1):492-7. Epub 2013 Dec 16.

Epilepsy Research Laboratory, Department of Neurological Surgery and Nina Ireland Laboratory of Developmental Neurobiology, Department of Psychiatry, University of California, San Francisco, CA 94143.

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http://dx.doi.org/10.1073/pnas.1307784111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890856PMC
January 2014

Many human accelerated regions are developmental enhancers.

Philos Trans R Soc Lond B Biol Sci 2013 Dec 11;368(1632):20130025. Epub 2013 Nov 11.

Gladstone Institutes, University of California, , San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1098/rstb.2013.0025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826498PMC
December 2013

Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.

Dev Biol 2014 Jan 21;385(1):94-106. Epub 2013 Oct 21.

Program on Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2013.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882892PMC
January 2014

Soluble guanylate cyclase generation of cGMP regulates migration of MGE neurons.

J Neurosci 2013 Oct;33(43):16897-914

Department of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, California 94158-2324, Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, and Cold Spring Harbor Laboratories, Laurel Hollow, New York 11791.

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http://dx.doi.org/10.1523/JNEUROSCI.1871-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866415PMC
October 2013

Subcortical origins of human and monkey neocortical interneurons.

Nat Neurosci 2013 Nov 6;16(11):1588-97. Epub 2013 Oct 6.

1] Institutes of Brain Science, Fudan University, Shanghai, China. [2] State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. [3].

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http://dx.doi.org/10.1038/nn.3536DOI Listing
November 2013

Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences.

Nat Neurosci 2013 Nov 6;16(11):1576-87. Epub 2013 Oct 6.

1] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA. [2] Department of Neurology, University of California, San Francisco, San Francisco, California, USA. [3].

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http://dx.doi.org/10.1038/nn.3541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191718PMC
November 2013

Dapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneurons.

PLoS One 2013 24;8(6):e67679. Epub 2013 Jun 24.

Biomedical Sciences Graduate Program, University of California San Francisco, San Francisco, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691262PMC
February 2014

GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior.

Nat Neurosci 2013 Jun 5;16(6):692-7. Epub 2013 May 5.

Epilepsy Research Laboratory, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nn.3392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665733PMC
June 2013

Inverse cancer comorbidity: a serendipitous opportunity to gain insight into CNS disorders.

Nat Rev Neurosci 2013 Apr;14(4):293-304

Department of Medicine, University of Valencia, CIBERSAM, INCLIVA, Blasco-Ibez 15, Valencia 46010, Spain.

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April 2013

CoupTFI interacts with retinoic acid signaling during cortical development.

PLoS One 2013 5;8(3):e58219. Epub 2013 Mar 5.

Department of Neurology, University of California San Francisco, San Francisco, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589372PMC
December 2013

A subpopulation of individual neural progenitors in the mammalian dorsal pallium generates both projection neurons and interneurons in vitro.

Stem Cells 2013 Jun;31(6):1193-201

Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1002/stem.1363DOI Listing
June 2013

Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons.

Neuron 2013 Jan;77(1):83-98

Department of Psychiatry, Neuroscience Program, and the Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco (UCSF), San Francisco, CA 94158-2324, USA.

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http://dx.doi.org/10.1016/j.neuron.2012.11.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547499PMC
January 2013

Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants.

J Comp Neurol 2013 May;521(7):1561-84

Department of Psychiatry and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, California 94158-2324, USA.

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http://dx.doi.org/10.1002/cne.23242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615175PMC
May 2013

Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate.

Dev Dyn 2012 Nov 28;241(11):1757-69. Epub 2012 Sep 28.

Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY 10010, USA.

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http://doi.wiley.com/10.1002/dvdy.23867
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988582PMC
November 2012

Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development.

Proc Natl Acad Sci U S A 2012 Sep 4;109(38):15491-6. Epub 2012 Sep 4.

Department of Developmental Biology and Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.1212899109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458400PMC
September 2012

Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.

Nature 2012 Sep 22;489(7416):385-90. Epub 2012 Aug 22.

Graduate Program in Neurobiology & Behavior, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1038/nature11356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448848PMC
September 2012

Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons.

J Comp Neurol 2013 Feb;521(2):479-97

Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/cne.23186DOI Listing
February 2013

Chronic reduction in inhibition reduces receptive field size in mouse auditory cortex.

Proc Natl Acad Sci U S A 2012 Aug 2;109(34):13829-34. Epub 2012 Jul 2.

Coleman Memorial Laboratory, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.1205909109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427089PMC
August 2012