John L Hays

John L Hays

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John L Hays

John L Hays

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24Publications

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Functional Loss Defines a Targetable Subset in Leiomyosarcoma.

Oncologist 2019 Jul 12;24(7):973-979. Epub 2018 Dec 12.

Division of Bioinformatics, Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio, USA

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http://theoncologist.alphamedpress.org/lookup/doi/10.1634/th
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http://dx.doi.org/10.1634/theoncologist.2018-0448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656468PMC
July 2019

Loss of TXNIP enhances peritoneal metastasis and can be abrogated by dual TORC1/2 inhibition.

Oncotarget 2018 Nov 2;9(86):35676-35686. Epub 2018 Nov 2.

Department of Biomedical Informatics, Division of Bioinformatics, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.18632/oncotarget.26281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235015PMC
November 2018

The Omics Revolution Continues: The Maturation of High-Throughput Biological Data Sources.

Yearb Med Inform 2018 Aug 29;27(1):211-222. Epub 2018 Aug 29.

Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1055/s-0038-1667085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115204PMC
August 2018

Use of Targeted Therapeutics in Epithelial Ovarian Cancer: A Review of Current Literature and Future Directions.

Clin Ther 2018 03 23;40(3):361-371. Epub 2018 Feb 23.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1016/j.clinthera.2018.01.012DOI Listing
March 2018

Temozolomide post pazopanib treatment failure in patients with advanced sarcoma: A case series.

PLoS One 2017 15;12(11):e0188116. Epub 2017 Nov 15.

Department of Internal Medicine, Division of Medical Oncology, Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188116PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687737PMC
December 2017

Addition of Everolimus Post VEGFR Inhibition Treatment Failure in Advanced Sarcoma Patients Who Previously Benefited from VEGFR Inhibition: A Case Series.

PLoS One 2016 13;11(6):e0156985. Epub 2016 Jun 13.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156985PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905654PMC
July 2017

Outpatient desensitization in selected patients with platinum hypersensitivity reactions.

Gynecol Oncol 2017 06 11;145(3):603-610. Epub 2017 Apr 11.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.ygyno.2017.03.015DOI Listing
June 2017

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

Authors:
Yosr Hamdi Penny Soucy Karoline B Kuchenbaeker Tomi Pastinen Arnaud Droit Audrey Lemaçon Julian Adlard Kristiina Aittomäki Irene L Andrulis Adalgeir Arason Norbert Arnold Banu K Arun Jacopo Azzollini Anita Bane Laure Barjhoux Daniel Barrowdale Javier Benitez Pascaline Berthet Marinus J Blok Kristie Bobolis Valérie Bonadona Bernardo Bonanni Angela R Bradbury Carole Brewer Bruno Buecher Saundra S Buys Maria A Caligo Jocelyne Chiquette Wendy K Chung Kathleen B M Claes Mary B Daly Francesca Damiola Rosemarie Davidson Miguel De la Hoya Kim De Leeneer Orland Diez Yuan Chun Ding Riccardo Dolcetti Susan M Domchek Cecilia M Dorfling Diana Eccles Ros Eeles Zakaria Einbeigi Bent Ejlertsen Christoph Engel D Gareth Evans Lidia Feliubadalo Lenka Foretova Florentia Fostira William D Foulkes George Fountzilas Eitan Friedman Debra Frost Pamela Ganschow Patricia A Ganz Judy Garber Simon A Gayther Anne-Marie Gerdes Gord Glendon Andrew K Godwin David E Goldgar Mark H Greene Jacek Gronwald Eric Hahnen Ute Hamann Thomas V O Hansen Steven Hart John L Hays Frans B L Hogervorst Peter J Hulick Evgeny N Imyanitov Claudine Isaacs Louise Izatt Anna Jakubowska Paul James Ramunas Janavicius Uffe Birk Jensen Esther M John Vijai Joseph Walter Just Katarzyna Kaczmarek Beth Y Karlan Carolien M Kets Judy Kirk Mieke Kriege Yael Laitman Maïté Laurent Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Annelie Liljegren Niklas Loman Jennifer T Loud Siranoush Manoukian Milena Mariani Sylvie Mazoyer Lesley McGuffog Hanne E J Meijers-Heijboer Alfons Meindl Austin Miller Marco Montagna Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Robert L Nussbaum Edith Olah Olufunmilayo I Olopade Kai-Ren Ong Jan C Oosterwijk Ana Osorio Laura Papi Sue Kyung Park Inge Sokilde Pedersen Bernard Peissel Pedro Perez Segura Paolo Peterlongo Catherine M Phelan Paolo Radice Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Andrea Richardson Mark Robson Gustavo C Rodriguez Matti A Rookus Rita Katharina Schmutzler Nicolas Sevenet Payal D Shah Christian F Singer Thomas P Slavin Katie Snape Johanna Sokolowska Ida Marie Heeholm Sønderstrup Melissa Southey Amanda B Spurdle Zsofia Stadler Dominique Stoppa-Lyonnet Grzegorz Sukiennicki Christian Sutter Yen Tan Muy-Kheng Tea Manuel R Teixeira Alex Teulé Soo-Hwang Teo Mary Beth Terry Mads Thomassen Laima Tihomirova Marc Tischkowitz Silvia Tognazzo Amanda Ewart Toland Nadine Tung Ans M W van den Ouweland Rob B van der Luijt Klaartje van Engelen Elizabeth J van Rensburg Raymonda Varon-Mateeva Barbara Wappenschmidt Juul T Wijnen Timothy Rebbeck Georgia Chenevix-Trench Kenneth Offit Fergus J Couch Silje Nord Douglas F Easton Antonis C Antoniou Jacques Simard

Breast Cancer Res Treat 2017 01 28;161(1):117-134. Epub 2016 Oct 28.

Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, 2705 Laurier Boulevard, Quebec, QC, G1V 4G2, Canada.

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http://dx.doi.org/10.1007/s10549-016-4018-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222911PMC
January 2017

Autophagy Induction Results in Enhanced Anoikis Resistance in Models of Peritoneal Disease.

Mol Cancer Res 2017 01 2;15(1):26-34. Epub 2016 Nov 2.

Department of Internal Medicine, Division of Medical Oncology, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0200-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909689PMC
January 2017

Olaparib in the management of ovarian cancer.

Pharmgenomics Pers Med 2015 7;8:127-35. Epub 2015 Aug 7.

Department of Hematology Oncology, Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.2147/PGPM.S62809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538690PMC
August 2015

Phase I/Ib study of olaparib and carboplatin in BRCA1 or BRCA2 mutation-associated breast or ovarian cancer with biomarker analyses.

J Natl Cancer Inst 2014 Jun 19;106(6):dju089. Epub 2014 May 19.

Affiliations of authors: Medical Oncology Branch, Center for Cancer Research (J-ML, JLH, CMA, AMN, LM, JAZ, MY, NG, TMS, WDF, NA, ECK), National Clinical Target Validation Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research (JJ), Center for Interventional Oncology, Radiology, and Imaging Sciences, Clinical Center and National Cancer Institute (BJW), and Division of Cancer Treatment and Diagnosis, National Cancer Institute (JD), National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1093/jnci/dju089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049120PMC
June 2014

The Role of PARP Inhibitors in the Treatment of Gynecologic Malignancies.

Front Oncol 2013 Oct 1;3:237. Epub 2013 Oct 1.

Division of Medical Oncology, Department of Internal Medicine, The James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center , Columbus, OH , USA.

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http://dx.doi.org/10.3389/fonc.2013.00237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787651PMC
October 2013

Proteomics and ovarian cancer: integrating proteomics information into clinical care.

J Proteomics 2010 Sep 1;73(10):1864-72. Epub 2010 Jun 1.

Molecular Signaling Section, Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1906, USA.

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http://dx.doi.org/10.1016/j.jprot.2010.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939206PMC
September 2010

Biochemical basis for the functional switch that regulates hepatocyte growth factor receptor tyrosine kinase activation.

Biochemistry 2008 Apr 7;47(13):4028-38. Epub 2008 Mar 7.

Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-0645, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi701892f
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http://dx.doi.org/10.1021/bi701892fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729649PMC
April 2008

Distinct functions of retinoic acid receptor beta isoforms: implications for targeted therapy.

Endocr Metab Immune Disord Drug Targets 2008 Mar;8(1):47-50

Department of Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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March 2008

Oligomerization-dependent changes in the thermodynamic properties of the TPR-MET receptor tyrosine kinase.

Biochemistry 2004 Aug;43(32):10570-8

Department of Human Biological Chemistry and Genetics and Sealy Center for Structural Biology, University of Texas Medical Branch, Galveston, Texas 77555-0645, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi0363275
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http://dx.doi.org/10.1021/bi0363275DOI Listing
August 2004

Oligomerization-induced modulation of TPR-MET tyrosine kinase activity.

J Biol Chem 2003 Jul 23;278(30):27456-63. Epub 2003 Apr 23.

Department of Human Biological Chemistry and Genetics and the Sealy Center for Structural Biology, University of Texas Medical Branch, Galveston, Texas 77555-0645, USA.

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http://dx.doi.org/10.1074/jbc.M210648200DOI Listing
July 2003