John Koreth

John Koreth

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John Koreth

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Incidence, Predictors, and Outcomes of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Reduced-Intensity Allogeneic Hematopoietic Cell Transplantation.

Biol Blood Marrow Transplant 2019 Oct 31. Epub 2019 Oct 31.

Department of Medical Oncology, Division of Hematologic Malignancies, Dana-Farber Cancer, Institute, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.10.024DOI Listing
October 2019

A post-transplant optimized transplant-specific risk score in myelodysplastic syndromes.

Haematologica 2019 May;104(5):859-861

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.3324/haematol.2018.214452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518899PMC
May 2019

Early Clinical Predictors of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Myeloablative Stem Cell Transplantation.

Biol Blood Marrow Transplant 2019 01 3;25(1):137-144. Epub 2018 Aug 3.

Division of Hematologic Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.07.039DOI Listing
January 2019

Impact of Thrombotic Microangiopathy on Renal Outcomes and Survival after Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2018 11 11;24(11):2344-2353. Epub 2018 May 11.

Transplantation Research Center, Brigham and Women's Hospital, Boston, Massachusetts; Division of Renal Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230502PMC
November 2018

Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.

J Clin Oncol 2017 May 9;35(14):1598-1605. Epub 2017 Jan 9.

Christopher J. Gibson, R. Coleman Lindsley, Brenton G. Mar, Jiantao Shi, Ann S. Lacasce, Arnold S. Freedman, David C. Fisher, Eric Jacobsen, Philippe Armand, Edwin P. Alyea, John Koreth, Vincent Ho, Robert J. Soiffer, Joseph H. Antin, Jerome Ritz, Sarah Nikiforow, Franziska Michor, and Donna Neuberg, Dana-Farber Cancer Institute; Jiantao Shi and Franziska Michor, Harvard T.H. Chan School of Public Health; Siddhartha Jaiswal, Elizabeth A. Morgan, and Benjamin L. Ebert, Brigham and Women's Hospital, Boston; Benjamin L. Ebert, Broad Institute, Cambridge, MA; Vatche Tchekmedyian, Memorial Sloan Kettering Cancer Center, New York, NY; Alysia Bosworth, Anita Bansal, and Stephen J. Forman, City of Hope National Medical Center, Duarte, CA; and Liton Francisco, Jianbo He, Ravi Bhatia, and Smita Bhatia, University of Alabama at Birmingham, Birmingham, AL.

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http://dx.doi.org/10.1200/JCO.2016.71.6712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455707PMC
May 2017

Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect?

Haematologica 2017 05;102(5):806-808

Division of Hematologic Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

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http://dx.doi.org/10.3324/haematol.2017.165266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477598PMC
May 2017

Mechanistic approaches for the prevention and treatment of chronic GVHD.

Blood 2017 01 7;129(1):22-29. Epub 2016 Nov 7.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://www.bloodjournal.org/content/early/2016/11/07/blood-2
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http://dx.doi.org/10.1182/blood-2016-08-686659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216263PMC
January 2017

An Open-Label Phase II Randomized Trial of Topical Dexamethasone and Tacrolimus Solutions for the Treatment of Oral Chronic Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2016 11 30;22(11):2084-2091. Epub 2016 Aug 30.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.bbmt.2016.08.020DOI Listing
November 2016

A phase I study of CD25/regulatory T-cell-depleted donor lymphocyte infusion for relapse after allogeneic stem cell transplantation.

Haematologica 2016 10 27;101(10):1251-1259. Epub 2016 Jun 27.

Division of Hematologic Malignancies, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.3324/haematol.2015.141176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046655PMC
October 2016

Ipilimumab for Patients with Relapse after Allogeneic Transplantation.

N Engl J Med 2016 Jul;375(2):143-53

From the Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School (M.S.D., H.T.K., P.B., R.L., A.S., A.P.L., M.H., M.S., F.S.H., C.J.W., V.T.H., C. Cutler, J.K., E.P.A., J.H.A., P.A., J.R., R.J.S.), the Bone Marrow Transplant Program, Beth Israel Deaconess Medical Center and Harvard Medical School (D.A.), the Bone Marrow Transplant Program, Massachusetts General Hospital Cancer Center and Harvard Medical School (Y.-B.C.), the Departments of Dermatology (N.R.L.) and Pathology (S.R.G., J.L.H., S.J.R.), Dana-Farber and Brigham and Women's Cancer Center, and the Dana-Farber Cancer Institute, Center for Molecular Oncologic Pathology (M.B., C.W.Z.) - all in Boston; Broad Institute of Massachusetts Institute of Technology and Harvard (P.B., C.J.W.) and Neon Therapeutics (M.S.R.) - both in Cambridge; the Blood and Marrow Transplant Program, University of California, San Diego, Moores Cancer Center, La Jolla (C. Costello, E.D.B.); Colorado Blood Cancer Institute, Denver (P.M.); Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD (H.S.); and the Blood and Marrow Transplant Group of Georgia at Northside Hospital, Atlanta (A.B.).

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http://dx.doi.org/10.1056/NEJMoa1601202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149459PMC
July 2016

Improved Treatment-Related Mortality and Overall Survival of Patients with Grade IV Acute GVHD in the Modern Years.

Biol Blood Marrow Transplant 2016 May 31;22(5):910-8. Epub 2015 Dec 31.

Division of Hematology-Oncology, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.bbmt.2015.12.024DOI Listing
May 2016

Circulating T follicular helper cells with increased function during chronic graft-versus-host disease.

Blood 2016 05 4;127(20):2489-97. Epub 2016 Mar 4.

Division of Hematologic Malignancies and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Harvard Medical School, Boston, MA; Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA.

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http://dx.doi.org/10.1182/blood-2015-12-688895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874229PMC
May 2016

Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD.

Blood 2016 Feb 15;127(5):646-57. Epub 2015 Dec 15.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA; Harvard Medical School, Boston, MA; Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA; and.

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http://dx.doi.org/10.1182/blood-2015-10-672345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742552PMC
February 2016

Absolute lymphocyte count recovery after allogeneic hematopoietic stem cell transplantation predicts clinical outcome.

Biol Blood Marrow Transplant 2015 May 23;21(5):873-80. Epub 2015 Jan 23.

Department of Hematologic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.bbmt.2015.01.019DOI Listing
May 2015

Angiogenic cytokines are antibody targets during graft-versus-leukemia reactions.

Clin Cancer Res 2015 Mar 23;21(5):1010-8. Epub 2014 Dec 23.

Department of Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348150PMC
March 2015

Novel strategies to prevent relapse after allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia and myelodysplastic syndromes.

Curr Opin Hematol 2015 Mar;22(2):116-22

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000116DOI Listing
March 2015

Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells.

Nat Commun 2015 Jan 6;6:5906. Epub 2015 Jan 6.

Developmental Biology, Faculty of Sciences, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/ncomms6906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354291PMC
January 2015

A phase II study of bortezomib plus prednisone for initial therapy of chronic graft-versus-host disease.

Biol Blood Marrow Transplant 2014 Nov 10;20(11):1737-43. Epub 2014 Jul 10.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.06.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465759PMC
November 2014

Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation.

Haematologica 2014 Sep 23;99(9):1499-508. Epub 2014 May 23.

Division of Hematologic Malignancies and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA Harvard Medical School, Boston, MA, USA Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA, USA Harvard Stem Cell Institute, Boston, MA, USA

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http://dx.doi.org/10.3324/haematol.2014.104166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562540PMC
September 2014

Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation.

J Clin Oncol 2014 Sep 4;32(25):2691-8. Epub 2014 Aug 4.

Rafael Bejar and Bennett Caughey, University of California at San Diego, La Jolla, CA; Kristen E. Stevenson, R. Coleman Lindsley, Brenton G. Mar, David P. Steensma, Jerome Ritz, Robert Soiffer, Joseph H. Antin, Edwin Alyea, Philippe Armand, Vincent Ho, John Koreth, Donna Neuberg, and Corey S. Cutler, Dana-Farber Cancer Institute; R. Coleman Lindsley and Benjamin L. Ebert, Brigham and Women's Hospital, Harvard Medical School, Boston; Petar Stojanov, Gad Getz, and Benjamin L. Ebert, Broad Institute, Cambridge, MA.

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http://dx.doi.org/10.1200/JCO.2013.52.3381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207878PMC
September 2014

White blood cell recovery after allogeneic hematopoietic cell transplantation predicts clinical outcome.

Am J Hematol 2014 Jun 3;89(6):591-7. Epub 2014 Mar 3.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts.

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http://doi.wiley.com/10.1002/ajh.23695
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http://dx.doi.org/10.1002/ajh.23695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031274PMC
June 2014

Outcome and prognostic factors for patients who relapse after allogeneic hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2013 Dec 27;19(12):1713-8. Epub 2013 Sep 27.

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2013.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848699PMC
December 2013

Outcomes in patients age 70 or older undergoing allogeneic hematopoietic stem cell transplantation for hematologic malignancies.

Biol Blood Marrow Transplant 2013 Sep 18;19(9):1374-80. Epub 2013 Jun 18.

Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.bbmt.2013.06.008DOI Listing
September 2013

Tregs, HSCT, and acute GVHD: up close and personal.

Blood 2013 Sep;122(10):1690-1

Dana-Farber Cancer Institute, USA.

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http://dx.doi.org/10.1182/blood-2013-07-514125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765054PMC
September 2013

Paneth cells in gut GVHD: a Panglossian perspective.

Authors:
John Koreth

Blood 2013 Aug;122(8):1336-7

Dana-Farber Cancer Institute.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-06-50
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http://dx.doi.org/10.1182/blood-2013-06-509646DOI Listing
August 2013

Optimal positioning of hematopoietic stem cell transplantation for older patients with myelodysplastic syndromes.

Curr Opin Hematol 2013 Mar;20(2):150-6

Division of Hematologic Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1097/MOH.0b013e32835d8e8eDOI Listing
March 2013

Does iron overload really matter in stem cell transplantation?

Am J Hematol 2012 Jun 4;87(6):569-72. Epub 2012 Apr 4.

Departments of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1002/ajh.23188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358569PMC
June 2012

Hyperlipidemia and statin use after allogeneic hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2012 Apr 11;18(4):575-83. Epub 2011 Aug 11.

Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.bbmt.2011.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805283PMC
April 2012

Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant.

Blood 2012 Mar 30;119(9):1972-80. Epub 2011 Dec 30.

Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-11-35
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http://dx.doi.org/10.1182/blood-2011-11-354563DOI Listing
March 2012

Emerging therapies in hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2012 Jan;18(1 Suppl):S125-31

University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/j.bbmt.2011.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493856PMC
January 2012

Syngeneic donor hematopoietic stem cell transplantation is associated with high rates of engraftment syndrome.

Biol Blood Marrow Transplant 2011 Mar 24;17(3):421-8. Epub 2010 Sep 24.

Division of Hematologic Malignancies, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S108387911000393
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http://dx.doi.org/10.1016/j.bbmt.2010.09.013DOI Listing
March 2011