Professor John K Field, PhD, BDS, FRCPath - University of Liverpool - Professor

Professor John K Field

PhD, BDS, FRCPath

University of Liverpool

Professor

United Kingdom

ORCID logohttps://orcid.org/0000-0003-3951-6365

Professor John K Field, PhD, BDS, FRCPath - University of Liverpool - Professor

Professor John K Field

PhD, BDS, FRCPath

Introduction

Profile
Professor John Field, PhD, FRCPath has a Personal Clinical Chair in Molecular Oncology at the University of Liverpool. He is a Visiting Professor at University College London, holds the post of Director of Research of the Roy Castle Lung Cancer Research Programme. He is the Chief Investigator for the UK Lung Cancer Screening Trial (UKLS). Previous Chair of the IASLC Screening Prevention & Early Detection Committee and he formed IASLC Strategic Screening Advisory Group. Member of the ILCCO Steering Committee. He was presented with the IASLC Joseph Cullen Award at the WCLC 2011, in recognition of lifetime scientific achievements in lung cancer prevention research. He is Co-Chair of the IASLC Strategic Screening Advisory Committee and Co-lead on the IASLC Early Lung Cancer Imaging Confederation (ELIC) project.

He is the principle investigator of the Liverpool Lung Project, a molecular- epidemiological study into the early detection of lung cancer (~13,000 recruited), funded by the Roy Castle Lung Cancer Foundation. The UKLS and the LLP form part of the NCRI Lung Cancer portfolio. A Partner in the FP7 CURELUNG and LCAOS projects and co-applicant on the recently funded NIH U19 programme grant; also contributed to the lung cancer genetic susceptibility ‘Lung Oncoarray’ project. He is also heavily involved in the identification of molecular diagnostic markers in lung and head & neck cancers. His research funding has been provided mainly by the RCF, NWCRF, MRC, CRUK, EU, NIH and the HTA.

Professor Field is the author of over 300 international (peer reviewed) papers in his area of expertise and has given more than 350 presentations at medical and scientific conferences around the world.


http://www.liverpoollungproject.co.uk
http://www.ukls.org/
https://www.mendeley.com/profiles/john-field3/

Primary Affiliation: University of Liverpool - United Kingdom

Experience

Jan 1998
Professor John K Field
Clinical Professor of Molecular Oncology
Department of Molecular and Clinical Cancer Medicine

Publications

520Publications

6423Reads

15Profile Views

3256PubMed Central Citations

Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response.

Lung Cancer 2019 Aug 5;134:79-84. Epub 2019 Jun 5.

Department of Cellular Pathology, Royal Liverpool University Hospital, Duncan Building, Daulby Street, Liverpool, L7 8XP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658831PMC
August 2019
5 Reads
3.958 Impact Factor

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 515.33 TERT-CLPTM1Ll Region.

J Thorac Oncol 2019 Aug 19;14(8):1360-1369. Epub 2019 Apr 19.

Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833942PMC
August 2019
45 Reads
5.282 Impact Factor

Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers.

Int J Epidemiol 2019 06;48(3):751-766

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/ije/dyy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659464PMC
June 2019
50 Reads
9.180 Impact Factor

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.

Cancer Epidemiol Biomarkers Prev 2019 May 30;28(5):935-942. Epub 2019 Jan 30.

Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0356DOI Listing
May 2019
38 Reads
4.125 Impact Factor

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Oncotarget 2019 Mar 5;10(19):1760-1774. Epub 2019 Mar 5.

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.18632/oncotarget.26678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442994PMC
March 2019
17 Reads
6.359 Impact Factor

Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges.

J Thorac Oncol 2019 03 4;14(3):343-357. Epub 2018 Dec 4.

Solid Tumors Program, Centro de Investigación Médica Aplicada, Pamplona, Spain; Navarra Institute for Health Research, Pamplona, Spain; CIBERONC, Centro de Investigación Biomédica en Red de Cáncer, Madrid, Spain; Department of Pathology, Anatomy and Physiology, School of Medicine, University of Navarra, Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494979PMC
March 2019
24 Reads
5.282 Impact Factor

Lung cancer CT screening: are we ready to consider screening biennially in a subgroup of low-risk individuals?

Thorax 2018 11 28;73(11):1006-1007. Epub 2018 Jun 28.

Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2018-211814DOI Listing
November 2018
16 Reads
8.290 Impact Factor

EUPS-argues that lung cancer screening should be implemented in 18 months.

Br J Radiol 2018 Oct 24;91(1090):20180243. Epub 2018 May 24.

4 University Medical Center Groningen, Center for Medical Imaging, University of Groningen , Groningen , The Netherlands.

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http://dx.doi.org/10.1259/bjr.20180243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350482PMC
October 2018
6 Reads
1.533 Impact Factor

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity.

Nat Commun 2018 09 25;9(1):3927. Epub 2018 Sep 25.

International Agency for Research on Cancer, World Health Organization, Lyon, 69372 cedex 08, France.

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http://dx.doi.org/10.1038/s41467-018-05890-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156406PMC
September 2018
35 Reads
10.742 Impact Factor

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.

Authors:
Xuemei Ji Yohan Bossé Maria Teresa Landi Jiang Gui Xiangjun Xiao David Qian Philippe Joubert Maxime Lamontagne Yafang Li Ivan Gorlov Mariella de Biasi Younghun Han Olga Gorlova Rayjean J Hung Xifeng Wu James McKay Xuchen Zong Robert Carreras-Torres David C Christiani Neil Caporaso Mattias Johansson Geoffrey Liu Stig E Bojesen Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert Chu Chen M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier A Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher Haiman Lynne Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Erik H F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer Doherty Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske Judith Manz Thomas Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard Houlston John McLaughlin Victoria Stevens David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song María Soler Artigas Martin D Tobin Louise V Wain Fangyi Gu Jinyoung Byun Ahsan Kamal Dakai Zhu Rachel F Tyndale Wei-Qi Wei Stephen Chanock Paul Brennan Christopher I Amos

Nat Commun 2018 08 13;9(1):3221. Epub 2018 Aug 13.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, 03750, NH, USA.

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http://dx.doi.org/10.1038/s41467-018-05074-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089967PMC
August 2018
90 Reads
10.742 Impact Factor

Utilizing Lung Cancer Risk Prediction Models to Promote Smoking Cessation: Two Randomized Controlled Trials.

Am J Health Promot 2018 06 25;32(5):1196-1205. Epub 2016 Oct 25.

2 Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1177/0890117116673820DOI Listing
June 2018
21 Reads
2 Citations

Patient selection for future lung cancer computed tomography screening programmes: lessons learnt post National Lung Cancer Screening Trial.

Transl Lung Cancer Res 2018 Apr;7(Suppl 2):S114-S116

Respiratory Medicine Unit, David Evans Research Centre, Nottingham University Hospitals, Nottingham, UK.

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http://dx.doi.org/10.21037/tlcr.2018.03.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943231PMC
April 2018
5 Reads

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Carcinogenesis 2018 03;39(3):336-346

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1093/carcin/bgx113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248554PMC
March 2018
112 Reads
1 Citation
5.334 Impact Factor

Low-dose CT for lung cancer screening - Authors' reply.

Lancet Oncol 2018 03;19(3):e135-e136

University of Groningen, University Medical Center Groningen, Center for Medical Imaging, Groningen, Netherlands.

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http://dx.doi.org/10.1016/S1470-2045(18)30122-0DOI Listing
March 2018
26 Reads
24.690 Impact Factor

European position statement on lung cancer screening.

Lancet Oncol 2017 12;18(12):e754-e766

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30861-6DOI Listing
December 2017
177 Reads
10 Citations
24.690 Impact Factor

Age at menopause and hormone replacement therapy as risk factors for head and neck and oesophageal cancer (Review).

Oncol Rep 2017 Oct 1;38(4):1915-1922. Epub 2017 Aug 1.

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool Institute of Translational Medicine, Liverpool L7 8TX, UK.

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https://www.spandidos-publications.com/10.3892/or.2017.5867
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http://dx.doi.org/10.3892/or.2017.5867DOI Listing
October 2017
17 Reads
2.191 Impact Factor

Scientific Advances in Thoracic Oncology 2016.

Authors:

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

http://europepmc.org/abstract/med/28579481

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August 2017
3 Reads

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

Authors:

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

http://europepmc.org/abstract/med/27697780

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January 2017

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

Authors:
Christopher I Amos Joe Dennis Zhaoming Wang Jinyoung Byun Fredrick R Schumacher Simon A Gayther Graham Casey David J Hunter Thomas A Sellers Stephen B Gruber Alison M Dunning Kyriaki Michailidou Laura Fachal Kimberly Doheny Amanda B Spurdle Yafang Li Xiangjun Xiao Jane Romm Elizabeth Pugh Gerhard A Coetzee Dennis J Hazelett Stig E Bojesen Charlisse Caga-Anan Christopher A Haiman Ahsan Kamal Craig Luccarini Daniel Tessier Daniel Vincent François Bacot David J Van Den Berg Stefanie Nelson Stephen Demetriades David E Goldgar Fergus J Couch Judith L Forman Graham G Giles David V Conti Heike Bickeböller Angela Risch Melanie Waldenberger Irene Brüske-Hohlfeld Belynda D Hicks Hua Ling Lesley McGuffog Andrew Lee Karoline Kuchenbaecker Penny Soucy Judith Manz Julie M Cunningham Katja Butterbach Zsofia Kote-Jarai Peter Kraft Liesel FitzGerald Sara Lindström Marcia Adams James D McKay Catherine M Phelan Sara Benlloch Linda E Kelemen Paul Brennan Marjorie Riggan Tracy A O'Mara Hongbing Shen Yongyong Shi Deborah J Thompson Marc T Goodman Sune F Nielsen Andrew Berchuck Sylvie Laboissiere Stephanie L Schmit Tameka Shelford Christopher K Edlund Jack A Taylor John K Field Sue K Park Kenneth Offit Mads Thomassen Rita Schmutzler Laura Ottini Rayjean J Hung Jonathan Marchini Ali Amin Al Olama Ulrike Peters Rosalind A Eeles Michael F Seldin Elizabeth Gillanders Daniela Seminara Antonis C Antoniou Paul D P Pharoah Georgia Chenevix-Trench Stephen J Chanock Jacques Simard Douglas F Easton

Cancer Epidemiol Biomarkers Prev 2017 01 3;26(1):126-135. Epub 2016 Oct 3.

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224974PMC
January 2017
86 Reads
33 Citations
4.125 Impact Factor

Lung Cancer Among Firefighters: Smoking-Adjusted Risk Estimates in a Pooled Analysis of Case-Control Studies.

J Occup Environ Med 2016 11;58(11):1137-1143

The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (Drs Bigert, Gustavsson); International Agency for Research on Cancer, Lyon, France (Drs Straif, Schüz, Olsson); Institute for Prevention and Occupational Medicine of the German Social Accident Insurance - Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany (Drs Taeger, Pesch, Kendzia, Brüning); Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Environmental Epidemiology of Cancer Team (Drs Stücker, Guida); Université Paris-Sud, UMRS 1018, F-94807, Villejuif, France (Drs Stücker, Guida); Institut für Epidemiologie I, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg (Dr Brüske); Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians University (Dr Wichmann); Helmholtz Center Munich, Institute of Epidemiology I (Dr Wichmann); Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, Germany (Dr Wichmann); Department of Clinical Sciences and Community Health, Università degli Studi di Milano and IRCCS Ca' Granda Foundation, Milan, Italy (Dr Pesatori); National Cancer Institute, Bethesda, Maryland (Drs Landi, Caporaso); Division of Occupational and Environmental Health, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China (Drs Tse, Yu); Research Centre of University of Montréal Hospital Centre, University of Montréal, Montréal, Quebec, Canada (Drs Siemiatycki, Lavoué); Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy (Drs Richiardi, Mirabelli); Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy (Dr Simonato); Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany (Dr Jöckel); Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany (Drs Ahrens, Pohlabeln); CIBERESP, University of Oviedo, Oviedo, Spain (Dr Tardón); Russian Cancer Research Centre, Moscow, Russia (Dr Zaridze); Roy Castle Lung Cancer Research Programme, Cancer Research Centre, University of Liverpool, Liverpool, UK (Dr Field); Centre for Public Health Research, Massey University, Wellington, New Zealand (Drs 't Mannetje, Pearce); Public Health Ontario, Toronto (Dr McLaughlin); Occupational Cancer Research Centre, Cancer Care Ontario, Ontario, Toronto, Canada (Dr Demers); The Nofer Institute of Occupational Medicine, Lodz (Dr Szeszenia-Dabrowska); The M Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland (Dr Lissowska); National Public Health Center, Budapest, Hungary (Dr Rudnai); Regional Authority of Public Health, Banska Bystrica, Slovakia (Dr Fabianova); Institute of Public Health, Bucharest, Romania (Dr Stanescu Dumitru); Institute of Hygiene and Epidemiology, 1st Faculty of Medicine, Charles University, Prague (Dr Bencko); Masaryk Memorial Cancer Institute, Brno, Czech Republic (Dr Foretova); Palacky University, Faculty of Medicine, Olomouc (Dr Janout); Faculty of Medicine, Ostrava University, Ostrava, Czech Republic (Dr Janout); The Tisch Cancer Institute and Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, New York (Dr Boffetta); Institute for Risk Assessment Sciences, Utrecht, the Netherlands (Drs Peters, Vermeulen, Kromhout); and Occupational Respiratory Epidemiology, School of Population Health, University of Western Australia, Perth, Western Australia, Australia (Dr Peters).

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http://dx.doi.org/10.1097/JOM.0000000000000878DOI Listing
November 2016
226 Reads
1 Citation
1.800 Impact Factor

P1.04: Defining the Genetic Architecture of Lung Cancer Etiology: Track: Prevention, Early Detection, Epidemiology and Tobacco Control.

Authors:

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

http://europepmc.org/abstract/med/27676490

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October 2016

Circulating tumour DNA and resistance mechanisms during EGFR inhibitor therapy in lung cancer.

J Thorac Dis 2016 Sep;8(9):2357-2359

Roy Castle Lung Cancer Research Programme, Institute of Translational Medicine, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool, L7 8TX, Liverpool, UK.

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http://dx.doi.org/10.21037/jtd.2016.07.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059349PMC
September 2016
20 Reads
2 Citations

Implementation planning for lung cancer screening: five major challenges.

Lancet Respir Med 2016 09;4(9):685-687

Nottingham University Hospitals and Respiratory Medicine Unit, David Evans Centre, Nottingham City Hospital Campus, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1016/S2213-2600(16)30233-8DOI Listing
September 2016
25 Reads
4 Citations

Incorporating epistasis interaction of genetic susceptibility single nucleotide polymorphisms in a lung cancer risk prediction model.

Int J Oncol 2016 Jul 25;49(1):361-70. Epub 2016 Apr 25.

Roy Castle Lung Cancer Research Programme, The University of Liverpool, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, Liverpool L7 8TX, UK.

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http://dx.doi.org/10.3892/ijo.2016.3499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902078PMC
July 2016
20 Reads
2 Citations
3.025 Impact Factor

Electronic cigarettes: a survey of perceived patient use and attitudes among members of the British thoracic oncology group.

Respir Res 2016 05 17;17(1):55. Epub 2016 May 17.

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, The Apex Building, 6 West Derby Street, Liverpool, L7 8TX, UK.

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http://dx.doi.org/10.1186/s12931-016-0367-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869376PMC
May 2016
21 Reads
4 Citations

Perceptions towards electronic cigarettes for smoking cessation among Stop Smoking Service users.

Br J Health Psychol 2016 May 16;21(2):421-33. Epub 2015 Dec 16.

Department of Sociology, Social Policy and Criminology, University of Liverpool, UK.

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http://dx.doi.org/10.1111/bjhp.12177DOI Listing
May 2016
17 Reads
3 Citations

Lung cancer CT screening: is annual screening necessary?

Lancet Oncol 2016 05 18;17(5):543-4. Epub 2016 Mar 18.

Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/S1470-2045(16)00079-6DOI Listing
May 2016
14 Reads
3 Citations
24.690 Impact Factor

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

J Natl Cancer Inst 2015 Nov 29;107(11). Epub 2015 Aug 29.

: Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada (RJH, YB, JGP); National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany (CMU, AR); Mayo Clinic, Rochester, MN (ELG, DNR); The University of Warwick, Coventry, UK (KM); Massachusetts General Hospital, Boston, MA (ATC); University of Hawaii Cancer Center, Honolulu, HI (LLM); Duke University, Durham, NC (JS); University of California at San Francisco, San Francisco, CA (JSW); Institute of Cancer Research, London, UK (RE, RH, ZKJ); Mount Sinai School of Medicine, New York, NY (PBo); Baylor College of Medicine, Houston, TX (MRS); Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS (BLF); Moffitt Cancer Center, Tampa, FL (ZC, CP, TAS); University of South California, Los Angeles, CA (CH, FS, GC, SBG, BH); Cambridge University, Cambridge, UK (DFE, AAAO, HS); National Cancer Institute, Bethesda, MD (MTL, SC, SIB, NW); International Agency for Research on Cancer, Lyon, France (PBr); Harvard School of Public Health, Boston, MA (DCC, PK, SL, DJH); University of Liverpool, Liverpool, UK (JKF); University of Göttingen, Medical School, Göttingen, Germany (HB); Karolinska Institutet, Stockholm, Sweden (FW, HG); Fred Hutchinson Cancer Research Center, Seattle, WA (UP); University of Utah Health Sciences Center and Huntsman Cancer Institute, Salt Lake City, UT (CMU, MLS); Geisel School of Medicine, Dartmouth College, Lebanon, NH (CIA).

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http://jnci.oxfordjournals.org/content/107/11/djv246.full.pd
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv24
Publisher Site
http://dx.doi.org/10.1093/jnci/djv246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675100PMC
November 2015
117 Reads
19 Citations
12.583 Impact Factor

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020.

Int J Oncol 2015 Aug 15;47(2):739-46. Epub 2015 Jun 15.

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool L3 9TA, UK.

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http://dx.doi.org/10.3892/ijo.2015.3049DOI Listing
August 2015
28 Reads
1 Citation
3.025 Impact Factor

Comprehensive genomic profiles of small cell lung cancer.

Nature 2015 Aug 13;524(7563):47-53. Epub 2015 Jul 13.

1] Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany. [2] Department of Pathology, University Hospital Cologne, 50937 Cologne, Germany.

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http://dx.doi.org/10.1038/nature14664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861069PMC
August 2015
169 Reads
190 Citations
42.351 Impact Factor

Trends and regional variation in the incidence of head and neck cancers in England: 2002 to 2011.

Int J Oncol 2015 Jul 7;47(1):204-10. Epub 2015 May 7.

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool L3 9TA, UK.

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http://dx.doi.org/10.3892/ijo.2015.2990DOI Listing
July 2015
13 Reads
4 Citations
3.025 Impact Factor

LLPi: Liverpool Lung Project Risk Prediction Model for Lung Cancer Incidence.

Cancer Prev Res (Phila) 2015 Jun 14;8(6):570-5. Epub 2015 Apr 14.

Roy Castle Lung Cancer Research Programme, the University of Liverpool Cancer Research Centre, Institute of Translational Medicine, the University of Liverpool. Liverpool L3 9TA, UK.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0438DOI Listing
June 2015
10 Reads
7 Citations

Lung cancer screening: identifying the high risk cohort.

J Thorac Dis 2015 Apr;7(Suppl 2):S156-62

Roy Castle Lung Cancer Research Programme, the University of Liverpool Cancer Research Centre, Institute of Translational Medicine, the University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2015.04.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419032PMC
April 2015
10 Reads
6 Citations

Impact of comorbidity on lung cancer mortality - a report from the Liverpool Lung Project.

Oncol Lett 2015 Apr 28;9(4):1902-1906. Epub 2015 Jan 28.

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, Liverpool Cancer Research UK Centre, Institute of Translational Medicine, The University of Liverpool, Liverpool L3 9TA, UK.

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http://dx.doi.org/10.3892/ol.2015.2916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356386PMC
April 2015
18 Reads
3 Citations
0.990 Impact Factor

E-cigarettes and cancer patients

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

http://www.scopus.com/inward/record.url?eid=2-s2.0-84903702684&partnerID=MN8TOARS

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2014
1 Read

Education and lung cancer among never smokers.

Epidemiology 2014 Nov;25(6):934-5

INSERM, UMR_S 1136, Pierre Louis Institute of Epidemiology and Public Health, Paris, France Inserm U1018, Center for Epidemiology and Population Health, Villejuif, France Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany The University of Liverpool Cancer Research Centre, Institute of Translational Medicine, Liverpool, United Kingdom Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada Department of Pharmaceutical Sciences, Washington State University College of Pharmacy, Spokane, WA Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain Karmanos Cancer Institute, Wayne State University, Detroit, MI Saw Swee Hock School of Public Health, National University of Singapore, Singapore Dan L. Duncan Cancer Center, Houston, TX Departamento de Medicina, University of Oviedo, Campus del Cristo s/n, Oviedo, Asturias, Spain Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA Inserm U1085, Irset, 97110 Pointe-à-Pitre, Guadeloupe, French West Indies,

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November 2014
37 Reads
1 Citation
6.200 Impact Factor

Factors associated with dropout in a lung cancer high‑risk cohort--the Liverpool lung project.

Int J Oncol 2014 Jun 7;44(6):2146-52. Epub 2014 Apr 7.

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Institute of Translational Medicine, The University of Liverpool, Liverpool L3 9TA, UK.

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http://dx.doi.org/10.3892/ijo.2014.2371DOI Listing
June 2014
10 Reads
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E-cigarettes and cancer patients.

J Thorac Oncol 2014 Apr;9(4):438-41

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1097/JTO.0000000000000129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040965PMC
April 2014
48 Reads
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5.282 Impact Factor

Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia.

J Natl Cancer Inst 2014 Apr 28;106(4):dju061. Epub 2014 Mar 28.

Affiliations of authors: Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (SLP, FRS, CAH); Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (MDF, JMK, AY, YL, UP, CC, CK); Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council Human Genetics Unit, Edinburgh, UK (MT); Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI (CPC, LRW, LL); Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH (YH, CIA); Department of Epidemiology (S-AL, AB, KEN, GH) and Carolina Center for Genome Sciences (KEN), University of North Carolina, Chapel Hill, NC; Molecular Physiology and Biophysics (LD, DCC), Center for Human Genetics Research (LD, RG, HD, DCC, WSB), Vanderbilt Epidemiology Center (JHF), and Biomedical Informatics (WSB), Vanderbilt University, Nashville, TN; Division of Genomic Medicine, National Human Genome Research Institute (LH), and Division of Cancer Epidemiology and Genetics, National Cancer Institute (DA, NC, MTL), National Institutes of Health, Bethesda, MD; Department of Statistics and Biostatistics, Rutgers University, Piscataway, NJ (SB); Information Sciences Institute, University of Southern California, Marina del Rey, CA (ED); Department of Oncology, School of Medicine, Wayne State University, Detroit, Michigan (MLC); M.D. Anderson Cancer Center, Houston, TX (WC, MP); Harvard University School of Public Health, Boston, MA (DCC); Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool Cancer Research Centre, Institute of Translational Medicine, The University of Liverpool, Liverpool, UK (JKF); Department of Genetic Epidemiology, University Medical Centre Göttingen, Göttingen, Germany (HB); DKFZ-German Cancer Research Center and Translatio

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April 2014
49 Reads
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12.583 Impact Factor

The UK Lung Screen (UKLS): demographic profile of first 88,897 approaches provides recommendations for population screening.

Cancer Prev Res (Phila) 2014 Mar 17;7(3):362-71. Epub 2014 Jan 17.

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, The University of Liverpool, Roy Castle Building, 200 London Road, Liverpool L3 9TA, United Kingdom.

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March 2014
27 Reads
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Lung cancer screening with low dose computed tomography.

BMJ 2014 Mar 7;348:g1970. Epub 2014 Mar 7.

Respiratory Medicine Unit, David Evans Research Centre, Nottingham University Hospitals, Nottingham NG5 1PB, UK.

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March 2014
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The International Association Study Lung Cancer (IASLC) Strategic Screening Advisory Committee (SSAC) response to the USPSTF recommendations.

J Thorac Oncol 2014 Feb;9(2):141-3

*Department of Molecular and Clinical Cancer Medicine, Institute of Translational medicine, The University of Liverpool Cancer Research Centre, Liverpool, United Kingdom; †Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, California; ‡Division of Thoracic Surgery, New York Presbyterian-Weill, Cornell, New York, New York; §Respiratory Medicine Unit, Nottingham University Hospitals, Nottingham, United Kingdom; ‖Rockville, Maryland;¶Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom; #National Heart and Lung Institute, Imperial College, London, United Kingdom; **University of Colorado, Cancer Center, Denver, Colorado; ††Department of Cardiothoracic Surgery, University of Copenhagen, Copenhagen, Denmark; ‡‡Department of Public Health, Erasmus MC, Rotterdam, The Netherlands; §§Rush University, Chicago, Illinois; ‖‖Department of Radiology, Duke University, Medical Center, Durham, North Carolina; ¶¶Princess Margaret Cancer Centre and University of Toronto, Toronto, Canada; and ##Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

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February 2014
38 Reads
4 Citations
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Epigenetic biomarkers in lung cancer.

Cancer Lett 2014 Jan 27;342(2):200-12. Epub 2012 Apr 27.

University of Liverpool, Institute of Translational Medicine, Department of Molecular & Clinical Cancer Medicine, Liverpool, United Kingdom. Electronic address:

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January 2014
50 Reads
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5.621 Impact Factor

CT screening for lung cancer: countdown to implementation.

Lancet Oncol 2013 Dec;14(13):e591-600

Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, Liverpool, UK. Electronic address:

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December 2013
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A prognostic DNA methylation signature for stage I non-small-cell lung cancer.

Authors:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

http://europepmc.org/abstract/med/24081945

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December 2013

A prognostic DNA methylation signature for stage I non-small-cell lung cancer.

J Clin Oncol 2013 Nov 30;31(32):4140-7. Epub 2013 Sep 30.

Juan Sandoval, Jesus Mendez-Gonzalez, F. Javier Carmona, Sergi Sayols, Sebastian Moran, Holger Heyn, Miguel Vizoso, Antonio Gomez, Montse Sanchez-Cespedes, and Manel Esteller, Bellvitge Biomedical Research Institute; Josefina Mora, Hospital de la Santa Creu i Sant Pau; Manel Esteller, University of Barcelona and Institucio Catalana de Recerca i Estudis Avançats, Barcelona; Miquel Taron and Rafael Rosell, Catalan Institute of Oncology, Badalona, Catalonia; Marina Pollan, Instituto de Salud Carlos III, Madrid; Maria J. Pajares and Luis M. Montuenga, University of Navarra; Wenceslao Torre, Clínica University de Navarra, Pamplona, Spain; Ernest Nadal, Guoan Chen, and David G. Beer, University of Michigan Medical School, Ann Arbor, MI; Yassen Assenov and Fabian Müller, Max Planck Institute, Saarbrücken, Germany; Christoph Bock, Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Lucia A. Muscarella, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Triantafillos Liloglou, Michael Davies, and John K. Field, The University of Liverpool Cancer Research Centre, Liverpool, United Kingdom; Elisabeth Brambilla, Centre Hospitalier Universitaire A Michallon, Grenoble, France; Luca Roz, IRCCS Foundation National Cancer Institute, Milan; Marco Lo Iacono and Giorgio V. Scagliotti, University of Torino, Orbassano (Torino), Italy.

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November 2013
59 Reads
57 Citations
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European randomized lung cancer screening trials: Post NLST.

J Surg Oncol 2013 Oct 25;108(5):280-6. Epub 2013 Jul 25.

The University of Liverpool Cancer Research Centre, Liverpool, UK.

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http://dx.doi.org/10.1002/jso.23383DOI Listing
October 2013
22 Reads
11 Citations
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The contribution of risk prediction models to early detection of lung cancer.

J Surg Oncol 2013 Oct 29;108(5):304-11. Epub 2013 Aug 29.

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool Cancer Research Centre, Liverpool, UK.

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October 2013
45 Reads
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Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines.

Hum Mol Genet 2013 Aug 15;22(16):3207-17. Epub 2013 Apr 15.

Department of Molecular and Clinical Cancer Medicine, Roy Castle Lung Cancer Research Programme, University of Liverpool, 200 London Rd, Liverpool L3 9TA,UK.

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http://dx.doi.org/10.1093/hmg/ddt174DOI Listing
August 2013
62 Reads
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Prospects for population screening and diagnosis of lung cancer.

Lancet 2013 Aug;382(9893):732-41

Roy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, The University of Liverpool Cancer Research Centre, Liverpool, UK.

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August 2013
14 Reads
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The role of DNA methylation as biomarkers in the clinical management of lung cancer.

Expert Rev Respir Med 2013 Aug;7(4):363-83

Molecular Biology Laboratory, Schwerpunkt Pneumologie, Universitätsklinik und Poliklinik für Innere Medizin I, Universitätsklinikum Halle (Saale), Ernst-Grube-Str. 40, 06120 Halle/Saale, Germany.

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August 2013
18 Reads
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TPL2 kinase is a suppressor of lung carcinogenesis.

Proc Natl Acad Sci U S A 2013 Apr 26;110(16):E1470-9. Epub 2013 Mar 26.

Molecular and Cellular Biology Laboratory, Division of Basic Sciences and Department of Pathology, University of Crete Medical School, 710 03 Heraklion, Greece.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631618PMC
April 2013
75 Reads
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In response. Predictive accuracy of the Liverpool Lung Project risk model.

Ann Intern Med 2013 Apr;158(7):568-9

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April 2013
31 Reads
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DNA methylation epigenotypes in breast cancer molecular subtypes.

Breast Cancer Res 2010 29;12(5):R77. Epub 2010 Sep 29.

BIOMICs Research Group, Centro de Investigacion y Estudios Avanzados ‘Lucio Lascaray’, University of the Basque Country UPV/EHU, Vitoria-Gazteiz, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096970PMC
February 2013
59 Reads
54 Citations

DNA methylation biomarkers offer improved diagnostic efficiency in lung cancer.

Cancer Res 2012 Nov 7;72(22):5692-701. Epub 2012 Sep 7.

Department of Molecular & Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500566PMC
November 2012
35 Reads
31 Citations
9.330 Impact Factor

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.

Hum Mol Genet 2012 Nov 16;21(22):4980-95. Epub 2012 Aug 16.

International Agency for Research on Cancer, Lyon, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607485PMC
November 2012
122 Reads
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6.393 Impact Factor

Predictive accuracy of the Liverpool Lung Project risk model for stratifying patients for computed tomography screening for lung cancer: a case-control and cohort validation study.

Ann Intern Med 2012 Aug;157(4):242-50

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Institute of Translational Medicine, The University of Liverpool, Liverpool L3 9TA, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723683PMC
August 2012
17 Reads
31 Citations
17.810 Impact Factor

Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort.

Eur Respir J 2012 Jul 20;40(1):177-84. Epub 2012 Jan 20.

International Prevention Research Institute, Lyon, France.

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July 2012
13 Reads
23 Citations
7.640 Impact Factor

Progressive lung cancer determined by expression profiling and transcriptional regulation.

Int J Oncol 2012 Jul 28;41(1):242-52. Epub 2012 Mar 28.

School of Computer Science, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.3892/ijo.2012.1421DOI Listing
July 2012
37 Reads
4 Citations
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Measurement methods and algorithms for the management of solid nodules.

J Thorac Imaging 2012 Jul;27(4):230-9

Department of Radiology, Royal Brompton Hospital, Sydney Street, London, UK.

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July 2012
19 Reads
1 Citation
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DNA methylation of the homeobox genes PITX2 and SHOX2 predicts outcome in non-small-cell lung cancer patients.

Diagn Mol Pathol 2012 Jun;21(2):93-104

Institute of Pathology, University Hospital Bonn, Bonn, Germany.

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June 2012
12 Reads
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2.275 Impact Factor

RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome.

Am J Hum Genet 2012 Feb 19;90(2):340-6. Epub 2012 Jan 19.

Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2011.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276661PMC
February 2012
25 Reads
35 Citations
10.931 Impact Factor

International Association for the Study of Lung Cancer Computed Tomography Screening Workshop 2011 report.

J Thorac Oncol 2012 Jan;7(1):10-9

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, The University of Liverpool, Liverpool, UK.

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January 2012
22 Reads
34 Citations
5.282 Impact Factor

Cytoglobin: biochemical, functional and clinical perspective of the newest member of the globin family.

Cell Mol Life Sci 2011 Dec 9;68(23):3869-83. Epub 2011 Jul 9.

Cancer Research Centre, Roy Castle Lung Cancer Research Programme, University of Liverpool, UK.

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December 2011
13 Reads
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Neuroglobin and myoglobin in non-small cell lung cancer: expression, regulation and prognosis.

Lung Cancer 2011 Dec 2;74(3):411-8. Epub 2011 Jun 2.

University of Liverpool Cancer Research Centre, Roy Castle Lung Cancer Research Programme, Liverpool L3 9TA, UK.

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December 2011
20 Reads
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Lung cancer risk prediction to select smokers for screening CT--a model based on the Italian COSMOS trial.

Cancer Prev Res (Phila) 2011 Nov 2;4(11):1778-89. Epub 2011 Aug 2.

Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0026DOI Listing
November 2011
22 Reads
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SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma.

J Thorac Oncol 2011 Oct;6(10):1632-8

Theracode GmbH, Mainz, Germany.

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October 2011
22 Reads
40 Citations
5.282 Impact Factor

UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.

Cancer 2011 Mar 8;117(5):1027-37. Epub 2010 Nov 8.

Roy Castle Lung Cancer Research Programme, University of Liverpool, Department of Clinical and Molecular Cancer Medicine, Liverpool, United Kingdom.

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March 2011
13 Reads
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4.890 Impact Factor

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.

Authors:
James D McKay Therese Truong Valerie Gaborieau Amelie Chabrier Shu-Chun Chuang Graham Byrnes David Zaridze Oxana Shangina Neonila Szeszenia-Dabrowska Jolanta Lissowska Peter Rudnai Eleonora Fabianova Alexandru Bucur Vladimir Bencko Ivana Holcatova Vladimir Janout Lenka Foretova Pagona Lagiou Dimitrios Trichopoulos Simone Benhamou Christine Bouchardy Wolfgang Ahrens Franco Merletti Lorenzo Richiardi Renato Talamini Luigi Barzan Kristina Kjaerheim Gary J Macfarlane Tatiana V Macfarlane Lorenzo Simonato Cristina Canova Antonio Agudo Xavier Castellsagué Ray Lowry David I Conway Patricia A McKinney Claire M Healy Mary E Toner Ariana Znaor Maria Paula Curado Sergio Koifman Ana Menezes Victor Wünsch-Filho José Eluf Neto Leticia Fernández Garrote Stefania Boccia Gabriella Cadoni Dario Arzani Andrew F Olshan Mark C Weissler William K Funkhouser Jingchun Luo Jan Lubiński Joanna Trubicka Marcin Lener Dorota Oszutowska Stephen M Schwartz Chu Chen Sherianne Fish David R Doody Joshua E Muscat Philip Lazarus Carla J Gallagher Shen-Chih Chang Zuo-Feng Zhang Qingyi Wei Erich M Sturgis Li-E Wang Silvia Franceschi Rolando Herrero Karl T Kelsey Michael D McClean Carmen J Marsit Heather H Nelson Marjorie Romkes Shama Buch Tomoko Nukui Shilong Zhong Martin Lacko Johannes J Manni Wilbert H M Peters Rayjean J Hung John McLaughlin Lars Vatten Inger Njølstad Gary E Goodman John K Field Triantafillos Liloglou Paolo Vineis Francoise Clavel-Chapelon Domenico Palli Rosario Tumino Vittorio Krogh Salvatore Panico Carlos A González J Ramón Quirós Carmen Martínez Carmen Navarro Eva Ardanaz Nerea Larrañaga Kay-Tee Khaw Timothy Key H Bas Bueno-de-Mesquita Petra H M Peeters Antonia Trichopoulou Jakob Linseisen Heiner Boeing Göran Hallmans Kim Overvad Anne Tjønneland Merethe Kumle Elio Riboli Kristjan Välk Tõnu Vooder Tõnu Voodern Andres Metspalu Diana Zelenika Anne Boland Marc Delepine Mario Foglio Doris Lechner Hélène Blanché Ivo G Gut Pilar Galan Simon Heath Mia Hashibe Richard B Hayes Paolo Boffetta Mark Lathrop Paul Brennan

PLoS Genet 2011 Mar 17;7(3):e1001333. Epub 2011 Mar 17.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060072PMC
March 2011
205 Reads
65 Citations

Global DNA hypomethylation-induced ΔNp73 transcriptional activation in non-small cell lung cancer.

Cancer Lett 2011 Jan;300(1):79-86

Roy Castle Lung Cancer Research Programme, The University of Liverpool, Department of Clinical and Molecular Cancer Medicine, 200 London Road, Liverpool L3 9TA, United Kingdom.

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http://dx.doi.org/10.1016/j.canlet.2010.09.009DOI Listing
January 2011
31 Reads
12 Citations
5.621 Impact Factor

Detection of DNA methylation changes in body fluids.

Adv Genet 2010 ;71:177-207

University of Liverpool Cancer Research Centre, Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/B978-0-12-380864-6.00006-7DOI Listing
November 2010
10 Reads
2 Citations
6.760 Impact Factor

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

Hum Immunol 2010 Oct 30;71(10):976-81. Epub 2010 Jun 30.

Division of Immunology, School of Infection and Host Defence, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/j.humimm.2010.06.019DOI Listing
October 2010
32 Reads
13 Citations
2.140 Impact Factor

Prognostic value of hTERT mRNA expression in surgical samples of lung cancer patients: the European Early Lung Cancer Project.

Int J Oncol 2010 Aug;37(2):455-61

Department of Pulmonary Diseases, VU University Medical Center, 1081 HV Amsterdam, The Netherlands.

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August 2010
42 Reads
3 Citations
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Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73gamma in lung cancer.

FEBS J 2010 Jul 7;277(14):3014-27. Epub 2010 Jun 7.

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07710.xDOI Listing
July 2010
27 Reads
5 Citations
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Incorporation of a genetic factor into an epidemiologic model for prediction of individual risk of lung cancer: the Liverpool Lung Project.

Cancer Prev Res (Phila) 2010 May 27;3(5):664-9. Epub 2010 Apr 27.

School of Cancer Studies, Liverpool Cancer Research Centre, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1158/1940-6207.CAPR-09-0141DOI Listing
May 2010
52 Reads
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The potential for using risk models in future lung cancer screening trials.

F1000 Med Rep 2010 May 24;2. Epub 2010 May 24.

Roy Castle Lung Cancer Research Programme, School of Cancer Studies, University of Liverpool Cancer Research Centre 200 London Road, Liverpool, L3 9TA UK.

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http://dx.doi.org/10.3410/M2-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950056PMC
May 2010
10 Reads
3 Citations

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.

Am J Hum Genet 2009 Nov 15;85(5):679-91. Epub 2009 Oct 15.

Division of Cancer Epidemiology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ajhg.2009.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775843PMC
November 2009
76 Reads
234 Citations
10.930 Impact Factor

Cancer diagnosis in first-degree relatives and non-small cell lung cancer risk: results from a multi-centre case-control study in Europe.

Eur J Cancer 2009 Nov 29;45(17):3047-53. Epub 2009 May 29.

Roy Castle Lung Cancer Research Programme, Cancer Research Centre, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/j.ejca.2009.05.006DOI Listing
November 2009
29 Reads
6 Citations
5.420 Impact Factor

Use of lung cancer risk models in planning research and service programs in CT screening for lung cancer.

Expert Rev Anticancer Ther 2009 Oct;9(10):1467-72

Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1586/era.09.87DOI Listing
October 2009
12 Reads
2 Citations
2.250 Impact Factor

A novel type of p53 pathway dysfunction in chronic lymphocytic leukemia resulting from two interacting single nucleotide polymorphisms within the p21 gene.

Cancer Res 2009 Jun 2;69(12):5210-7. Epub 2009 Jun 2.

Division of Haematology, University of Liverpool School of Cancer Studies, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0627DOI Listing
June 2009
19 Reads
13 Citations
9.330 Impact Factor

Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project.

Am J Respir Crit Care Med 2009 Mar 18;179(5):396-401. Epub 2008 Dec 18.

Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

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http://dx.doi.org/10.1164/rccm.200807-1153OCDOI Listing
March 2009
31 Reads
13 Citations
13.000 Impact Factor

Sample size determination in clinical proteomic profiling experiments using mass spectrometry for class comparison.

Proteomics 2009 Jan;9(1):74-86

Clinical and Biomedical Proteomics Group, Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1002/pmic.200800417DOI Listing
January 2009
23 Reads
9 Citations
3.810 Impact Factor

Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer.

Int J Cancer 2009 Jan;124(1):81-7

Roy Castle Lung Cancer Research Programme, The University of Liverpool, School of Cancer Studies, Liverpool, United Kingdom.

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http://dx.doi.org/10.1002/ijc.23849DOI Listing
January 2009
27 Reads
70 Citations
5.080 Impact Factor

A global approach to cancer-screening trials.

Lancet Oncol 2008 Oct 19;9(10):908-9. Epub 2008 Sep 19.

Cancer Screening, American Cancer Society, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/S1470-2045(08)70211-0DOI Listing
October 2008
25 Reads
2 Citations
24.690 Impact Factor

Lung cancer risk models come of age.

Authors:
John K Field

Cancer Prev Res (Phila) 2008 Sep;1(4):226-8

Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, 200 London Road, Liverpool L3 9TA, United Kingdom.

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http://dx.doi.org/10.1158/1940-6207.CAPR-08-0144DOI Listing
September 2008
11 Reads
3 Citations

Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene.

Cancer Res 2008 Sep;68(18):7448-56

Hamon Center for Therapeutic Oncology Research, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849650PMC
September 2008
37 Reads
35 Citations
9.330 Impact Factor

p16 Promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia.

Cancer Epidemiol Biomarkers Prev 2008 Aug;17(8):2174-9

Molecular Genetics and Oncology Group, Department of Clinical Dental Sciences, University of Liverpool, Liverpool L69 3GN, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-2867DOI Listing
August 2008
19 Reads
27 Citations
4.120 Impact Factor

Generation of a non-small cell lung cancer transcriptome microarray.

BMC Med Genomics 2008 May 30;1:20. Epub 2008 May 30.

Almac Diagnostics Ltd, 19 Seagoe Industrial Estate, Craigavon, BT63 5QD, UK.

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http://dx.doi.org/10.1186/1755-8794-1-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426710PMC
May 2008
25 Reads
13 Citations
2.870 Impact Factor

The role of pyrosequencing in head and neck cancer epigenetics: correlation of quantitative methylation data with gene expression.

Arch Otolaryngol Head Neck Surg 2008 Mar;134(3):251-6

Molecular Genetics & Oncology Group, School of Dental Sciences, University of Liverpool, Liverpool, England.

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http://dx.doi.org/10.1001/archoto.2007.50DOI Listing
March 2008
26 Reads
16 Citations
1.750 Impact Factor

Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma.

Br J Oral Maxillofac Surg 2007 Dec 7;45(8):617-22. Epub 2007 Jun 7.

Molecular Genetics & Oncology Group, School of Dental Sciences, University of Liverpool, Liverpool L69 3GN, UK.

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http://dx.doi.org/10.1016/j.bjoms.2007.04.015DOI Listing
December 2007
24 Reads
9 Citations
1.130 Impact Factor

CpG island methylation phenotype (CIMP) in oral cancer: associated with a marked inflammatory response and less aggressive tumour biology.

Oral Oncol 2007 Oct 25;43(9):878-86. Epub 2007 Jan 25.

Molecular Genetics and Oncology Group, School of Dental Sciences, University of Liverpool, Liverpool L69 3GN, UK.

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http://dx.doi.org/10.1016/j.oraloncology.2006.10.006DOI Listing
October 2007
17 Reads
18 Citations
3.610 Impact Factor

Seizure 6-like (SEZ6L) gene and risk for lung cancer.

Cancer Res 2007 Sep;67(17):8406-11

Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4784DOI Listing
September 2007
50 Reads
8 Citations
9.330 Impact Factor

Occupational exposure to crystalline silica and risk of lung cancer: a multicenter case-control study in Europe.

Epidemiology 2007 Jan;18(1):36-43

Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, University of Liverpool, United Kingdom.

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http://dx.doi.org/10.1097/01.ede.0000248515.28903.3cDOI Listing
January 2007
8 Reads
18 Citations
6.200 Impact Factor

Lung cancer risk prediction: a tool for early detection.

Int J Cancer 2007 Jan;120(1):1-6

Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, Liverpool, United Kingdom.

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http://dx.doi.org/10.1002/ijc.22331DOI Listing
January 2007
56 Reads
27 Citations
5.080 Impact Factor

Downregulation of the KIP family members p27(KIP1) and p57(KIP2) by SKP2 and the role of methylation in p57(KIP2) inactivation in nonsmall cell lung cancer.

Int J Cancer 2006 Dec;119(11):2546-56

Molecular Carcinogenesis Group, Laboratory of Histology-Embryology, Medical School, University of Athens, Athens, Greece.

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http://dx.doi.org/10.1002/ijc.22214DOI Listing
December 2006
19 Reads
22 Citations
5.080 Impact Factor

Cytosine methylation profiles as a molecular marker in non-small cell lung cancer.

Cancer Res 2006 Nov;66(22):10911-8

SEQUENOM, Inc., San Diego, California, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0400DOI Listing
November 2006
13 Reads
25 Citations
9.330 Impact Factor

Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer.

Hum Mol Genet 2006 Jul 12;15(13):2038-44. Epub 2006 May 12.

University of Liverpool Cancer Research Center, Roy Castle Lung Cancer Research Programme, Liverpool, UK.

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http://dx.doi.org/10.1093/hmg/ddl128DOI Listing
July 2006
62 Reads
19 Citations
6.390 Impact Factor

The Liverpool Statement 2005: priorities for the European Union/United States spiral computed tomography collaborative group.

J Thorac Oncol 2006 Jun;1(5):497-8

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, The University of Liverpool, Liverpool, UK.

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June 2006
1 Read
5.282 Impact Factor

Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing.

Nucleic Acids Res 2006 Jun 28;34(11):e78. Epub 2006 Jun 28.

Molecular Genetics and Oncology Group, School of Dental Sciences, University of Liverpool, Liverpool L69 3GN, UK.

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http://dx.doi.org/10.1093/nar/gkl424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904102PMC
June 2006
19 Reads
23 Citations
9.110 Impact Factor

Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancer.

Int J Oncol 2006 May;28(5):1295-301

Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, University of Liverpool, Liverpool L3 9TA, UK.

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May 2006
13 Reads
7 Citations
3.020 Impact Factor

Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression.

Hum Mol Genet 2006 Apr 1;15(8):1271-7. Epub 2006 Mar 1.

Molecular Genetics and Oncology Group, School of Dental Sciences, University of Liverpool, Edwards Building, Daulby Street, Liverpool L69 3GN, UK.

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http://dx.doi.org/10.1093/hmg/ddl042DOI Listing
April 2006
16 Reads
13 Citations
6.390 Impact Factor

The Liverpool Lung Project research protocol.

Int J Oncol 2005 Dec;27(6):1633-45

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, The University of Liverpool, Liverpool L3 9TA, UK.

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December 2005
9 Reads
3.025 Impact Factor

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry.

Proc Natl Acad Sci U S A 2005 Nov 21;102(44):15785-90. Epub 2005 Oct 21.

SEQUENOM, Inc., 3595 John Hopkins Court, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.0507816102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276092PMC
November 2005
47 Reads
296 Citations
9.810 Impact Factor

Methylation discriminators in NSCLC identified by a microarray based approach.

Int J Oncol 2005 Jul;27(1):105-11

Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, UK.

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http://dx.doi.org/10.3892/ijo.27.1.105DOI Listing
July 2005
2 Reads
3.025 Impact Factor