John J Worthington

John J Worthington

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John J Worthington

John J Worthington

Publications by authors named "John J Worthington"

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Long-term Treatment with Olanzapine Increases the Number of Sox2 and Doublecortin Expressing Cells in the Adult Subventricular Zone.

CNS Neurol Disord Drug Targets 2018 ;17(6):458-463

Department of Histology, School of Medicine in Katowice, Medical University of Silesia, ul. Medykow 18, 40-752, Katowice, Poland.

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http://dx.doi.org/10.2174/1871527317666180627113544DOI Listing
October 2019

Molecular neurochemistry of the lanthanides.

Synapse 2019 09 22;73(9):e22119. Epub 2019 Jun 22.

Faculty of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, Lancaster, UK.

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http://dx.doi.org/10.1002/syn.22119DOI Listing
September 2019

Chronic Antipsychotic Treatment Modulates Aromatase (CYP19A1) Expression in the Male Rat Brain.

J Mol Neurosci 2019 Jun 9;68(2):311-317. Epub 2019 Apr 9.

Department of Histology, School of Medicine in Katowice, Medical University of Silesia, ul. Medyków Street 18, 40-752, Katowice, Poland.

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http://dx.doi.org/10.1007/s12031-019-01307-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511348PMC
June 2019

A different ultrastructural face of ribbon synapses in the rat retina.

Anat Histol Embryol 2018 Dec 23;47(6):613-617. Epub 2018 Sep 23.

Faculty of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, Lancaster, UK.

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http://dx.doi.org/10.1111/ahe.12404DOI Listing
December 2018

Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala.

J Neural Transm (Vienna) 2018 07 27;125(7):1099-1105. Epub 2018 Feb 27.

Department of Histology, School of Medicine in Katowice, Medical University of Silesia, ul. Medyków 18, 40-752, Katowice, Poland.

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http://dx.doi.org/10.1007/s00702-018-1868-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999179PMC
July 2018

Medication disposal practices: Increasing patient and clinician education on safe methods.

J Int Med Res 2018 Mar 11;46(3):927-939. Epub 2018 Jan 11.

1 Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1177/0300060517738681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972255PMC
March 2018

The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa.

Neurochem Int 2018 02 15;113:120-136. Epub 2017 Dec 15.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, LA1 4YQ, UK.

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http://dx.doi.org/10.1016/j.neuint.2017.12.006DOI Listing
February 2018

Tuft Cells: A New Flavor in Innate Epithelial Immunity.

Trends Parasitol 2016 08 5;32(8):583-585. Epub 2016 May 5.

Faculty of Health and Medicine, University of Lancaster, Lancaster, UK. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2016.04.016DOI Listing
August 2016

Long-term treatment with haloperidol affects neuropeptide S and NPSR mRNA levels in the rat brain.

Acta Neuropsychiatr 2016 Apr 15;28(2):110-6. Epub 2015 Oct 15.

1Department of Histology,School of Medicine in Katowice,Medical University of Silesia,Katowice,Poland.

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https://www.cambridge.org/core/product/identifier/S092427081
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http://dx.doi.org/10.1017/neu.2015.56DOI Listing
April 2016

Effector Tregs: middle-men in TGFβ activation.

Oncotarget 2015 Aug;6(24):19958-9

Manchester Collaborative Centre for Inflammation Research, Faculty of Life Sciences, University of Manchester, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652975PMC
http://dx.doi.org/10.18632/oncotarget.4686DOI Listing
August 2015

The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease.

Biochem Soc Trans 2015 Aug 3;43(4):727-33. Epub 2015 Aug 3.

Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, M13 9PT, U.K.

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http://dx.doi.org/10.1042/BST20150090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613519PMC
August 2015

Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation.

Immunity 2015 May 12;42(5):903-15. Epub 2015 May 12.

Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester M13 9NT, UK; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK; Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448149PMC
May 2015

The novel neuropeptide phoenixin is highly co-expressed with nesfatin-1 in the rat hypothalamus, an immunohistochemical study.

Neurosci Lett 2015 Apr 28;592:17-21. Epub 2015 Feb 28.

Department of Histology, Medical University of Silesia, ul. Medyków 18, Katowice 40-752, Poland.

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http://dx.doi.org/10.1016/j.neulet.2015.02.060DOI Listing
April 2015

Neurolight -astonishing advances in brain imaging.

Int J Neurosci 2015 Feb 23;125(2):91-9. Epub 2014 May 23.

1Department of Histology, Medical University of Silesia , 18 Medyków Street, Katowice , Poland.

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http://www.tandfonline.com/doi/full/10.3109/00207454.2014.91
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http://dx.doi.org/10.3109/00207454.2014.914511DOI Listing
February 2015

Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity.

PLoS Pathog 2013 3;9(10):e1003675. Epub 2013 Oct 3.

Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom ; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom ; Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1003675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789784PMC
May 2014

Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion.

PLoS Pathog 2013 Jan 17;9(1):e1003122. Epub 2013 Jan 17.

Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, UK.

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https://dx.plos.org/10.1371/journal.ppat.1003122
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http://dx.doi.org/10.1371/journal.ppat.1003122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547840PMC
January 2013

Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells.

Immunobiology 2012 Dec 2;217(12):1259-65. Epub 2012 Jul 2.

Manchester Immunology Group, Faculty of Life Sciences, AV Hill Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01712985120014
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http://dx.doi.org/10.1016/j.imbio.2012.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690473PMC
December 2012

Intestinal dendritic cells specialize to activate transforming growth factor-β and induce Foxp3+ regulatory T cells via integrin αvβ8.

Gastroenterology 2011 Nov 30;141(5):1802-12. Epub 2011 Jun 30.

Manchester Immunology Group and Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1053/j.gastro.2011.06.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507624PMC
November 2011

Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: a randomized, double-blind, placebo-controlled trial.

J Clin Psychiatry 2011 Jul 22;72(7):892-7. Epub 2011 Feb 22.

Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, One Bowdoin Square, Sixth Floor, Boston, MA 02114, USA.

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http://article.psychiatrist.com/?ContentType=START&ID=10
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http://dx.doi.org/10.4088/JCP.09m05607gryDOI Listing
July 2011

TGFβ: a sleeping giant awoken by integrins.

Trends Biochem Sci 2011 Jan 1;36(1):47-54. Epub 2010 Oct 1.

Manchester Immunology Group and Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1016/j.tibs.2010.08.002DOI Listing
January 2011

Efficacy of CBT for benzodiazepine discontinuation in patients with panic disorder: Further evaluation.

Behav Res Ther 2010 Aug 28;48(8):720-7. Epub 2010 Apr 28.

Department of Psychology, Boston University, 648 Beacon Street, 5th Floor, Boston, MA 02215, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000579671000067
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http://dx.doi.org/10.1016/j.brat.2010.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962448PMC
August 2010

Next-step strategies for panic disorder refractory to initial pharmacotherapy: a 3-phase randomized clinical trial.

J Clin Psychiatry 2009 Nov 6;70(11):1563-70. Epub 2009 Oct 6.

Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Simches Research Building, 2nd Floor, 185 Cambridge St, Boston, MA 02114, USA.

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http://dx.doi.org/10.4088/JCP.08m04485bluDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995303PMC
November 2009

Open-label support for duloxetine for the treatment of panic disorder.

CNS Neurosci Ther 2009 ;15(1):19-23

Department of Psychiatry, Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1111/j.1755-5949.2008.00076.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494018PMC
April 2009

A PET study of tiagabine treatment implicates ventral medial prefrontal cortex in generalized social anxiety disorder.

Neuropsychopharmacology 2009 Jan 4;34(2):390-8. Epub 2008 Jun 4.

Department of Psychiatry, Psychiatric Neuroscience Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.

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http://dx.doi.org/10.1038/npp.2008.69DOI Listing
January 2009

Aripiprazole as augmentation treatment of refractory generalized anxiety disorder and panic disorder.

CNS Spectr 2008 Jun;13(6):522-7

Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1017/s109285290001676xDOI Listing
June 2008

Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: preliminary findings.

Psychopharmacology (Berl) 2008 May 2;197(4):675-81. Epub 2008 Feb 2.

Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00213-008-1087-xDOI Listing
May 2008

Levetiracetam as adjunctive therapy for refractory anxiety disorders.

J Clin Psychiatry 2007 Jul;68(7):1010-3

Anxiety Disorders Research Program, Cambridge Health Alliance, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.4088/jcp.v68n0705DOI Listing
July 2007

Preliminary support for gender differences in response to fluoxetine for generalized anxiety disorder.

Depress Anxiety 2006 ;23(6):373-6

Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1002/da.20184DOI Listing
January 2007

The combination of duloxetine and bupropion for treatment-resistant major depressive disorder.

Depress Anxiety 2006 ;23(3):178-81

Department of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, 02114, USA.

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http://doi.wiley.com/10.1002/da.20181
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http://dx.doi.org/10.1002/da.20181DOI Listing
November 2006

An open-label trial of risperidone augmentation for refractory anxiety disorders.

J Clin Psychiatry 2006 Mar;67(3):381-5

Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Boston, Mass, USA.

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http://dx.doi.org/10.4088/jcp.v67n0307DOI Listing
March 2006

Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: a placebo controlled study.

Biol Psychiatry 2006 Feb 1;59(3):211-5. Epub 2005 Sep 1.

Center for Anxiety and Traumatic Stress Related Disorders, Massachusetts General Hospital and Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1016/j.biopsych.2005.07.005DOI Listing
February 2006

Aripiprazole augmentation of selective serotonin reuptake inhibitors for treatment-resistant major depressive disorder.

J Clin Psychiatry 2005 Oct;66(10):1326-30

Department of Psychiatry, Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.4088/jcp.v66n1017DOI Listing
October 2005

Fluoxetine for vestibular dysfunction and anxiety: a prospective pilot study.

Psychosomatics 2005 Jul-Aug;46(4):334-9

Center for Anxiety and Traumatic Stress Related Disorders, Massachusetts General Hospital, WACC 815, Boston, MA 02114, USA.

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http://dx.doi.org/10.1176/appi.psy.46.4.334DOI Listing
September 2005

Aripiprazole as an augmentor of selective serotonin reuptake inhibitors in depression and anxiety disorder patients.

Int Clin Psychopharmacol 2005 Jan;20(1):9-11

Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/00004850-200501000-00002DOI Listing
January 2005

Bupropion sustained release for panic disorder.

Psychopharmacol Bull 2003 ;37(4):66-72

Department of Psychiatry, Harvard University, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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September 2004

An open-label study of levetiracetam for the treatment of social anxiety disorder.

J Clin Psychiatry 2004 Sep;65(9):1219-22

Center for Anxiety and Traumatic Stress Related Disorders, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.4088/jcp.v65n0909DOI Listing
September 2004

WSX-1: a key role in induction of chronic intestinal nematode infection.

J Immunol 2004 Jun;172(12):7635-41

School of Biological Sciences, 3.239 Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.172.12.7635DOI Listing
June 2004

Treatment of antidepressant-induced sexual dysfunction.

Drugs Today (Barc) 2003 Nov;39(11):887-96

Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1358/dot.2003.39.11.799466DOI Listing
November 2003

A pilot, open study of sertraline in outpatients with treatment-resistant depression (TRD) or with a history of TRD who responded but later relapsed.

Int Clin Psychopharmacol 2003 Sep;18(5):293-6

Depression Clinical and Research program, Department of Psychiatry, Massachusetts General Hospital, 156 Parkman Street, WACC #812, Boston, MA 02114, USA.

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http://dx.doi.org/10.1097/00004850-200309000-00006DOI Listing
September 2003

Combined paroxetine and clonazepam treatment strategies compared to paroxetine monotherapy for panic disorder.

J Psychopharmacol 2003 Sep;17(3):276-82

Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1177/02698811030173009DOI Listing
September 2003

A pilot, open study of sertraline in outpatients with treatment-resistant depression (TRD) or with a history of TRD who responded but later relapsed.

Int Clin Psychopharmacol 2003 Sep;18(5):293-6

Depression Clinical and Research program, Department of Psychiatry, Massachusetts General Hospital, 156 Parkman Street, WACC #812, Boston, MA 02114, USA.

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http://dx.doi.org/10.1097/00004850-200309000-00006DOI Listing
September 2003

Valproic acid for the treatment of social anxiety disorder.

Int Clin Psychopharmacol 2003 May;18(3):169-72

Massachusetts General Hospital, Boston 02114, USA.

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http://dx.doi.org/10.1097/01.yic.0000064261.66765.9fDOI Listing
May 2003

Lithium augmentation of nortriptyline for subjects resistant to multiple antidepressants.

J Clin Psychopharmacol 2003 Feb;23(1):92-5

Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1097/00004714-200302000-00013DOI Listing
February 2003

Nortriptyline for treatment-resistant depression.

J Clin Psychiatry 2003 Jan;64(1):35-9

Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA.

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http://dx.doi.org/10.4088/jcp.v64n0108DOI Listing
January 2003

A novel cognitive-behavioral approach for treatment-resistant drug dependence.

J Subst Abuse Treat 2002 Dec;23(4):335-42

Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/s0740-5472(02)00298-2DOI Listing
December 2002

Citalopram for social anxiety disorder: an open-label pilot study in refractory and nonrefractory patients.

CNS Spectr 2002 Sep;7(9):655-7

Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1017/s1092852900022148DOI Listing
September 2002

Body dysmorphic disorder in outpatients with major depression.

J Affect Disord 2002 May;69(1-3):141-8

Depression Research Program, Clinical Psychopharmacology Unit, Massachusetts General Hospital and The Consolidated Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA

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http://dx.doi.org/10.1016/s0165-0327(01)00304-4DOI Listing
May 2002

Hypothyroidism and hyperthyroidism in anxiety disorders revisited: new data and literature review.

J Affect Disord 2002 May;69(1-3):209-17

Anxiety Disorders Program, Massachusetts General Hospital and Harvard Medical School, 15 Parkman Street, WAC 815, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/s0165-0327(01)00378-0DOI Listing
May 2002