John J Reynolds

John J Reynolds

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John J Reynolds

John J Reynolds

Publications by authors named "John J Reynolds"

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17Publications

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Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ.

Neurol Genet 2019 Apr 25;5(2):e320. Epub 2019 Mar 25.

Department of Genome Dynamics (I.K., H.H., K.W.C.), Institute of Molecular Genetics of the Czech Academy of Sciences, Czech Republic; Genome Damage and Stability Centre (H.H., K.W.C.), School of Life Sciences, University of Sussex, Falmer, Brighton, UK; Institute of Human Genetics (Y.L., B.W., G.Y.), University Medical Center Göttingen, Germany; Cologne Center for Genomics (J.A.), University of Cologne, Germany; Institute of Cancer and Genomic Sciences (J.J.R., G.S.S.), College of Medical and Dental Sciences, University of Birmingham, UK; and Division of Genetics (N.G.), Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1212/NXG.0000000000000320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454307PMC
April 2019

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.

Mol Cell 2018 07 21;71(1):25-41.e6. Epub 2018 Jun 21.

Genome Stability and Human Disease Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039718PMC
July 2018

PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.

Mol Cell 2017 Mar 23;65(5):900-916.e7. Epub 2017 Feb 23.

Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344794PMC
March 2017

Expanding the ataxia with oculomotor apraxia type 4 phenotype.

Neurol Genet 2016 Feb 21;2(1):e49. Epub 2016 Jan 21.

Department of Neurology (M.P., P.S., R.P.) and Department of Genetics (H.M., A.N.), Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience (M.P., P.S., R.P.) and Department of Molecular Medicine and Surgery (H.M., A.N.), Karolinska Institutet, Stockholm, Sweden; and Institute of Cancer and Genomic Sciences (M.T., J.J.R.), University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1212/NXG.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817910PMC
February 2016

Another look at roles and functions: has hospital case management lost its way?

Authors:
John J Reynolds

Prof Case Manag 2013 Sep-Oct;18(5):246-54; quiz 255-6

Care Management & Patient Access, Saint Vincent’s Medical Center, 47 Long Lots Rd., Westport, CT 06880, USA.

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http://dx.doi.org/10.1097/NCM.0b013e31829c8aa8DOI Listing
July 2014

Reply: A single strand that links multiple neuropathologies in human disease.

Brain 2014 Apr 5;137(Pt 4):e267. Epub 2013 Aug 5.

School of Cancer Sciences, University of Birmingham, Birmingham, West Midlands, B15 2TT, UK.

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http://dx.doi.org/10.1093/brain/awt198DOI Listing
April 2014

A nervous predisposition to unrepaired DNA double strand breaks.

DNA Repair (Amst) 2013 Aug 17;12(8):588-99. Epub 2013 May 17.

School of Cancer Sciences, College of Medicine and Dentistry, University of Birmingham, IBR West Extension, First Floor, Vincent Drive, Edgbaston, Birmingham B15 2TT, United Kingdom.

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http://dx.doi.org/10.1016/j.dnarep.2013.04.011DOI Listing
August 2013

A single strand that links multiple neuropathologies in human disease.

Brain 2013 Jan;136(Pt 1):14-27

School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1093/brain/aws310DOI Listing
January 2013

Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair.

Nucleic Acids Res 2012 Aug 15;40(14):6608-19. Epub 2012 Apr 15.

Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton, BN1 9RQ, UK.

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http://dx.doi.org/10.1093/nar/gks318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413127PMC
August 2012

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair.

Nat Genet 2010 Mar 31;42(3):245-9. Epub 2010 Jan 31.

[1] Howard Hughes Medical Institute, Department of Neurology, Beth Israel Deaconess Medical Center and Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, USA. [2] These authors contributed equally to the work.

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http://dx.doi.org/10.1038/ng.526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835984PMC
March 2010

Short-patch single-strand break repair in ataxia oculomotor apraxia-1.

Biochem Soc Trans 2009 Jun;37(Pt 3):577-81

Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, UK.

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http://dx.doi.org/10.1042/BST0370577DOI Listing
June 2009

Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1.

Mol Cell Biol 2009 Mar 22;29(5):1354-62. Epub 2008 Dec 22.

Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, United Kingdom.

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http://dx.doi.org/10.1128/MCB.01471-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643831PMC
March 2009