John J Albers

John J Albers

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John J Albers

John J Albers

Publications by authors named "John J Albers"

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Structural basis of the lipid transfer mechanism of phospholipid transfer protein (PLTP).

Biochim Biophys Acta Mol Cell Biol Lipids 2018 09 5;1863(9):1082-1094. Epub 2018 Jun 5.

The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13881981183012
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http://dx.doi.org/10.1016/j.bbalip.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114099PMC
September 2018

Relationship of baseline HDL subclasses, small dense LDL and LDL triglyceride to cardiovascular events in the AIM-HIGH clinical trial.

Atherosclerosis 2016 08 11;251:454-459. Epub 2016 Jun 11.

University of Washington, Northwest Lipid Metabolism and Diabetes Research Laboratories, 401 Queen Anne Ave N, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983241PMC
August 2016

Lipoprotein (a) measurements for clinical application.

J Lipid Res 2016 Apr 4;57(4):526-37. Epub 2015 Dec 4.

Northwest Lipid Metabolism and Diabetes Research Laboratories, Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1194/jlr.R061648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808779PMC
April 2016

PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity.

J Lipid Res 2015 Jul 25;56(7):1351-62. Epub 2015 May 25.

Division of Medical Genetics, Department of Medicine, University of Washington School of Medicine, Seattle, WA Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA.

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http://dx.doi.org/10.1194/jlr.P058032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479339PMC
July 2015

Inhibition of thrombin generation in human plasma by phospholipid transfer protein.

Thromb J 2015 16;13:24. Epub 2015 Jul 16.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, MEM180, 10550 North Torrey Pines Rd., La Jolla, CA 92037 USA.

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http://dx.doi.org/10.1186/s12959-015-0054-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504036PMC
July 2015

Cerebrospinal fluid apolipoprotein E and phospholipid transfer protein activity are reduced in multiple sclerosis; relationships with the brain MRI and CSF lipid variables.

Mult Scler Relat Disord 2014 Jul;3(4):533-541

Neurological Laboratory, Department of Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.msard.2014.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061752PMC
July 2014

HDL-3 is a superior predictor of carotid artery disease in a case-control cohort of 1725 participants.

J Am Heart Assoc 2014 Jun 25;3(3):e000902. Epub 2014 Jun 25.

Division of Medical Genetics, Department of Medicine, University of Washington School of Medicine, Seattle, WA (D.S.K., A.A.B., E.A.R., J.E.R., C.E.F., G.P.J.) Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA (D.S.K., C.E.F., G.P.J.).

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https://www.ahajournals.org/doi/10.1161/JAHA.114.000902
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http://dx.doi.org/10.1161/JAHA.114.000902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309059PMC
June 2014

Lipoprotein lipase (LPL) is associated with neurite pathology and its levels are markedly reduced in the dentate gyrus of Alzheimer's disease brains.

J Histochem Cytochem 2013 Dec 4;61(12):857-68. Epub 2013 Sep 4.

Northwest Lipid Metabolism and Diabetes Research Laboratories, Department of Medicine, School of Medicine, University of Washington, Seattle, WA (HG, WD, SMM, JJA, SV).

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http://dx.doi.org/10.1369/0022155413505601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840745PMC
December 2013

Role of plasma phospholipid transfer protein in lipid and lipoprotein metabolism.

Biochim Biophys Acta 2012 Mar 28;1821(3):345-57. Epub 2011 Jun 28.

Northwest Lipid Metabolism and Diabetes Research Laboratories, Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, 401 Queen Anne Ave N, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/j.bbalip.2011.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192936PMC
March 2012

Impact of site-specific N-glycosylation on cellular secretion, activity and specific activity of the plasma phospholipid transfer protein.

Biochim Biophys Acta 2011 Jul 16;1814(7):908-11. Epub 2011 Apr 16.

Northwest Lipid Metrobolism and Diabetes Research Laboratories, Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, Washington 98109-4517, USA.

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http://dx.doi.org/10.1016/j.bbapap.2011.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112057PMC
July 2011

Lipoprotein(a) levels, apo(a) isoform size, and coronary heart disease risk in the Framingham Offspring Study.

J Lipid Res 2011 Jun 7;52(6):1181-7. Epub 2011 Apr 7.

Lipid Metabolism Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M012526
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http://dx.doi.org/10.1194/jlr.M012526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090239PMC
June 2011

Different phospholipid transfer protein complexes contribute to the variation in plasma PLTP specific activity.

Biochim Biophys Acta 2011 May 16;1811(5):343-7. Epub 2011 Feb 16.

Division of Metabolism, Endocrinology and Nutrition, Northwest Lipid Metabolism and Diabetes Research Laboratories, Department of Medicine, University of Washington, Seattle, WA 98109-4517, USA.

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http://dx.doi.org/10.1016/j.bbalip.2011.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075333PMC
May 2011

Evaluation of a new homogenous method for detection of small dense LDL cholesterol: comparison with the LDL cholesterol profile obtained by density gradient ultracentrifugation.

Clin Chim Acta 2011 Mar 11;412(7-8):556-61. Epub 2010 Dec 11.

Northwest Lipid Metabolism and Diabetes Research Laboratories, Department of Medicine, University of Washington, Seattle, WA 98109-4517, USA.

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http://dx.doi.org/10.1016/j.cca.2010.12.003DOI Listing
March 2011

Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation.

Biochemistry 2010 Aug;49(34):7314-22

Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, School of Medicine, University of Washington, Seattle, Washington 98109, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi100359f
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http://dx.doi.org/10.1021/bi100359fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930196PMC
August 2010

Phospholipid transfer protein reduces phosphorylation of tau in human neuronal cells.

J Neurosci Res 2009 Nov;87(14):3176-85

Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington School of Medicine, Seattle, Washington 98109, USA.

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http://doi.wiley.com/10.1002/jnr.22137
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http://dx.doi.org/10.1002/jnr.22137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755571PMC
November 2009

Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells.

J Lipid Res 2009 Oct 21;50(10):2095-102. Epub 2009 May 21.

Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, Department of Medicine, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1194/jlr.M900236-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739764PMC
October 2009

PLTP is present in the nucleus, and its nuclear export is CRM1-dependent.

Biochim Biophys Acta 2009 Mar 24;1793(3):584-91. Epub 2009 Jan 24.

Department of Medicine, Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, 401 Queen Anne Ave N, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2009.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692677PMC
March 2009

Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluid.

J Alzheimers Dis 2008 Nov;15(3):409-17

Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington School of Medicine, Seattle, WA 98109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667787PMC
November 2008

An amphipathic helical region of the N-terminal barrel of phospholipid transfer protein is critical for ABCA1-dependent cholesterol efflux.

J Biol Chem 2008 Apr 19;283(17):11541-9. Epub 2008 Feb 19.

Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, Box 356426, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1074/jbc.M800117200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431062PMC
April 2008

Prevalence and determinants of elevated apolipoprotein B and dense low-density lipoprotein in youths with type 1 and type 2 diabetes.

J Clin Endocrinol Metab 2008 Mar 18;93(3):735-42. Epub 2007 Dec 18.

Department of Medicine, Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, 401 Queen Anne Avenue North, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1210/jc.2007-2176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266957PMC
March 2008

Statins of different brain penetrability differentially affect CSF PLTP activity.

Dement Geriatr Cogn Disord 2006 7;22(5-6):392-8. Epub 2006 Sep 7.

Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.

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https://www.karger.com/Article/FullText/95679
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http://dx.doi.org/10.1159/000095679DOI Listing
February 2007

Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.

J Alzheimers Dis 2006 Dec;10(4):399-406

Department of Medicine, Division of Geriatric Medicine, University of Washington School of Medicine, and VA Puget Sound Health Care System, Seattle, WA 98108, USA.

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December 2006

Active plasma phospholipid transfer protein is associated with apoA-I- but not apoE-containing lipoproteins.

J Lipid Res 2006 Jun 6;47(6):1315-21. Epub 2006 Mar 6.

Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1194/jlr.M600042-JLR200DOI Listing
June 2006

Phospholipid transfer protein activity is associated with inflammatory markers in patients with cardiovascular disease.

Biochim Biophys Acta 2006 Jan 21;1762(1):131-7. Epub 2005 Sep 21.

Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA 98109-4517, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09254439050013
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http://dx.doi.org/10.1016/j.bbadis.2005.09.002DOI Listing
January 2006

Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro.

J Neurosci Res 2005 May;80(3):406-13

Department of Medicine, Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, Seattle, Washington 98109-4517, USA.

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http://dx.doi.org/10.1002/jnr.20458DOI Listing
May 2005

Low-density lipoprotein inhibits secretion of phospholipid transfer protein in human trophoblastic BeWo cells.

Exp Biol Med (Maywood) 2004 Nov;229(10):1046-52

Department of Medicine, Northwest Lipid Research Laboratories, Northwest Lipid Research Clinic, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, 2121 N 35th Street, Seattle, WA 98103, USA.

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http://dx.doi.org/10.1177/153537020422901009DOI Listing
November 2004

Emerging roles for phospholipid transfer protein in lipid and lipoprotein metabolism.

Curr Opin Lipidol 2004 Jun;15(3):255-60

Department of Medicine and Northwest Lipid Research Laboratories, University of Washington, 2121 North 35th Street, Seattle, WA 98103, USA.

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June 2004

Quantitative trait locus mapping of genes that regulate phospholipid transfer activity in SM/J and NZB/BlNJ inbred mice.

Arterioscler Thromb Vasc Biol 2004 Jan 30;24(1):155-60. Epub 2003 Oct 30.

The Jackson Laboratory, Bar Harbor, ME, USA.

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http://dx.doi.org/10.1161/01.ATV.0000104241.44819.10DOI Listing
January 2004

Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells.

J Biol Chem 2003 Dec 14;278(52):52379-85. Epub 2003 Oct 14.

Department of Medicine, University of Washington, Seattle, Washington 98195-6426, USA.

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http://dx.doi.org/10.1074/jbc.M310695200DOI Listing
December 2003

Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein(a) and Cardiovascular Disease: recent advances and future directions.

Clin Chem 2003 Nov;49(11):1785-96

Department of Medicine, University of Washington, Northwest Lipid Research Laboratories, 2121 N. 35th St., Seattle, WA 98103, USA.

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http://www.clinchem.org/content/49/11/1785.full.pdf
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November 2003

PLTP activity decreases with weight loss: changes in PLTP are associated with changes in subcutaneous fat and FFA but not IAF or insulin sensitivity.

J Lipid Res 2003 Sep 1;44(9):1705-12. Epub 2003 Jul 1.

Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, WA 98195, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M300073-JLR200
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http://dx.doi.org/10.1194/jlr.M300073-JLR200DOI Listing
September 2003

Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis.

Circulation 2003 Jul 30;108(3):270-4. Epub 2003 Jun 30.

Division of Cardiology, Department of Medicine, University of Washington, Seattle, Wash, USA.

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http://dx.doi.org/10.1161/01.CIR.0000079163.97653.CDDOI Listing
July 2003

Widespread distribution of PLTP in human CNS: evidence for PLTP synthesis by glia and neurons, and increased levels in Alzheimer's disease.

J Lipid Res 2003 Jun 1;44(6):1113-23. Epub 2003 Apr 1.

Department of Medicine, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1194/jlr.M300046-JLR200DOI Listing
June 2003

Selective and independent associations of phospholipid transfer protein and hepatic lipase with the LDL subfraction distribution.

J Lipid Res 2002 Aug;43(8):1256-63

Division of Metabolism, Endocrinology and Nutrition, University of Washington, Seattle, WA.

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http://www.jlr.org/content/43/8/1256.full.pdf
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August 2002

Association of plasma phospholipid transfer protein activity with IDL and buoyant LDL: impact of gender and adiposity.

Biochim Biophys Acta 2002 May;1587(1):53-9

Division of Metabolism, Endocrinology, and Nutrition, Northwest Lipid Research Laboratories, Seattle, WA 98103, USA.

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http://dx.doi.org/10.1016/s0925-4439(02)00054-6DOI Listing
May 2002

Differences in reactivity of antibodies to active versus inactive PLTP significantly impacts PLTP measurement.

J Lipid Res 2002 Feb;43(2):281-9

Northwest Lipid Research Laboratories, Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA 98103, USA.

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February 2002