John Horan

Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD.

J Clin Oncol 2021 Jan 15:JCO2001086. Epub 2021 Jan 15.

Boston Children's Hospital, Dana-Farber Cancer Institute, Boston, MA.

January 2021

Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8 T cells drive gastrointestinal acute graft-versus-host disease.

Sci Transl Med 2021 Jan;13(576)

Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

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January 2021

Hematopoietic stem cell transplant referral patterns for children with sickle cell disease vary among pediatric hematologist/oncologists' practice focus: A Sickle Cell Transplant Advocacy and Research Alliance (STAR) study.

Authors:

Emily Riehm Meier Allistair A Abraham Alex Ngwube Isaac A Janson Gregory M T Guilcher John Horan Kimberly A Kasow

Pediatr Blood Cancer 2021 Jan 6:e28861. Epub 2021 Jan 6.

Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina.

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January 2021

Human leukocyte antigen (HLA) class I antibodies and transfusion support in paediatric HLA-matched haematopoietic cell transplant for sickle cell disease.

Authors:

Robert S Nickel John T Horan Allistair Abraham Muna Qayed Ann Haight Alexander Ngwube Hua Liang Naomi L C Luban Jeanne E Hendrickson

Br J Haematol 2020 04 1;189(1):162-170. Epub 2019 Nov 1.

Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.

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April 2020

Mixed-phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force.

Cancer 2020 02 29;126(3):593-601. Epub 2019 Oct 29.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta/Emory University, Atlanta, Georgia.

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February 2020

Donor-specific anti-HLA antibodies in unrelated hematopoietic cell transplantation for non-malignant disorders.

Authors:

Ann Woolfrey Tao Wang Stephanie J Lee Michael D Haagenson Ge Chen Katharina Fleischhauer John Horan Katharine Hsu Michael Verneris Stephen R Spellman Marcelo Fernandez-Vina

Bone Marrow Transplant 2019 03 19;54(3):494-496. Epub 2018 Sep 19.

Stanford School of Medicine, Stanford, CA, USA.

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March 2019

The genetic basis and cell of origin of mixed phenotype acute leukaemia.

Authors:

Thomas B Alexander Zhaohui Gu Ilaria Iacobucci Kirsten Dickerson John K Choi Beisi Xu Debbie Payne-Turner Hiroki Yoshihara Mignon L Loh John Horan Barbara Buldini Giuseppe Basso Sarah Elitzur Valerie de Haas C Michel Zwaan Allen Yeoh Dirk Reinhardt Daisuke Tomizawa Nobutaka Kiyokawa Tim Lammens Barbara De Moerloose Daniel Catchpoole Hiroki Hori Anthony Moorman Andrew S Moore Ondrej Hrusak Soheil Meshinchi Etan Orgel Meenakshi Devidas Michael Borowitz Brent Wood Nyla A Heerema Andrew Carrol Yung-Li Yang Malcolm A Smith Tanja M Davidsen Leandro C Hermida Patee Gesuwan Marco A Marra Yussanne Ma Andrew J Mungall Richard A Moore Steven J M Jones Marcus Valentine Laura J Janke Jeffrey E Rubnitz Ching-Hon Pui Liang Ding Yu Liu Jinghui Zhang Kim E Nichols James R Downing Xueyuan Cao Lei Shi Stanley Pounds Scott Newman Deqing Pei Jaime M Guidry Auvil Daniela S Gerhard Stephen P Hunger Hiroto Inaba Charles G Mullighan

Nature 2018 10 12;562(7727):373-379. Epub 2018 Sep 12.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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October 2018

Treatment strategies for adolescent and young adult patients with acute myeloid leukemia.

Authors:

Kristen O'Dwyer David R Freyer John T Horan

Blood 2018 07 12;132(4):362-368. Epub 2018 Jun 12.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, GA.

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July 2018

Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival.

Authors:

Sunil S Raikar Sunita I Park Traci Leong David L Jaye Frank G Keller John T Horan William G Woods

Blood 2018 02 9;131(5):573-577. Epub 2017 Dec 9.

Department of Pediatrics, Emory University, Atlanta, GA.

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February 2018

Influence of Age on Acute and Chronic GVHD in Children Undergoing HLA-Identical Sibling Bone Marrow Transplantation for Acute Leukemia: Implications for Prophylaxis.

Biol Blood Marrow Transplant 2018 03 16;24(3):521-528. Epub 2017 Nov 16.

Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, Georgia.

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March 2018

Early blood stream infection following allogeneic hematopoietic stem cell transplantation is a risk factor for acute grade III-IV GVHD in children and adolescents.

Authors:

Hirozumi Sano Joseph A Hilinski Muna Qayed Kristy Applegate Joanna G Newton Benjamin Watkins Kuang-Yueh Chiang John Horan

Pediatr Blood Cancer 2018 Feb 17;65(2). Epub 2017 Sep 17.

Aflac Cancer and Blood Disorders Center, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia.

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February 2018

CD36-positive B-lymphoblasts Predict Poor Outcome in Children With B-lymphoblastic Leukemia.

Authors:

Joanna G Newton John T Horan Scott Newman Michael R Rossi Rhett P Ketterling Sunita I Park

Pediatr Dev Pathol 2017 Jun 8;20(3):224-231. Epub 2017 Feb 8.

6 Department of Pathology, Children's Healthcare of Atlanta - Egleston, Emory University, Atlanta, Georgia, USA.

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June 2017

African American Race Is a Newly Identified Risk Factor for Postengraftment Blood Stream Infections in Pediatric Allogeneic Blood and Marrow Transplantation.

Authors:

Hirozumi Sano Joseph A Hilinski Kristy Applegate Kuang-Yueh Chiang Ann Haight Muna Qayed John Horan

Biol Blood Marrow Transplant 2017 Feb 10;23(2):357-360. Epub 2016 Nov 10.

Aflac Cancer and Blood Disorders Center, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia.

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February 2017

Leukoreduced red blood cell transfusions do not induce platelet glycoprotein antibodies in patients with sickle cell disease.

Authors:

Robert Sheppard Nickel Anne M Winkler John T Horan Jeanne E Hendrickson

Transfusion 2016 09 6;56(9):2267-73. Epub 2016 Jul 6.

Department of Pediatrics, Yale University, New Haven, Connecticut.

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September 2016

Haematopoietic stem cell transplantation for sickle cell disease - current practice and new approaches.

Authors:

Staci D Arnold Monica Bhatia John Horan Lakshmanan Krishnamurti

Br J Haematol 2016 08 2;174(4):515-25. Epub 2016 Jun 2.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University School of Medicine, Department of Pediatrics, Atlanta, GA, USA.

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August 2016