John Gamble

John Gamble

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John Gamble

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A Proposal for an Alternative Approach to Particle Size Method Development During Early-Stage Small Molecule Pharmaceutical Development.

J Pharm Sci 2019 Nov 21;108(11):3515-3520. Epub 2019 Aug 21.

Malvern Panalytical, Enigma Business Park, Grovewood Road, Malvern, Worcestershire WR14 1XZ, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00223549193050
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http://dx.doi.org/10.1016/j.xphs.2019.08.007DOI Listing
November 2019

Improved in vivo targeting of BCL-2 phenotypic conversion through hollow gold nanoshell delivery.

Apoptosis 2019 Jun;24(5-6):529-537

Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA.

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http://dx.doi.org/10.1007/s10495-019-01531-1DOI Listing
June 2019

Successful Ascending Aorta and Hemiarch Replacement and Aortic Valve Resuspension Via Redo Median Sternotomy Using Hypothermic Circulatory Arrest in a Practicing Jehovah's Witnesses Patient.

J Cardiothorac Vasc Anesth 2019 May 21;33(5):1447-1454. Epub 2018 Dec 21.

Society for Advanced Blood Management, Englewood, NJ; Department of Cardiovascular Surgery, Yavapai Regional Medical Center, Prescott, AZ.

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http://dx.doi.org/10.1053/j.jvca.2018.12.019DOI Listing
May 2019

Quantification of glioblastoma progression in zebrafish xenografts: Adhesion to laminin alpha 5 promotes glioblastoma microtumor formation and inhibits cell invasion.

Biochem Biophys Res Commun 2018 12 30;506(4):833-839. Epub 2018 Oct 30.

Oregon State University, Biochemistry and Biophysics Department, Corvallis, OR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.10.076DOI Listing
December 2018

Enhanced Understanding of Pharmaceutical Materials Through Advanced Characterisation and Analysis.

AAPS PharmSciTech 2018 Nov 8;19(8):3462-3480. Epub 2018 Nov 8.

Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

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http://link.springer.com/10.1208/s12249-018-1198-6
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http://dx.doi.org/10.1208/s12249-018-1198-6DOI Listing
November 2018

Determination of process variables affecting drug particle attrition withinmulti-component blends during powder feed transmission.

Pharm Dev Technol 2017 Nov 27;22(7):904-909. Epub 2016 Jun 27.

a Drug Product Science & Technology , Bristol-Myers Squibb , Moreton , Wirral , UK.

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http://dx.doi.org/10.1080/10837450.2016.1200616DOI Listing
November 2017

Airway Management in a Patient with Wolf-Hirschhorn Syndrome.

Case Rep Pediatr 2016 26;2016:7070125. Epub 2016 Sep 26.

Department of Anesthesiology, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA.

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http://dx.doi.org/10.1155/2016/7070125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056284PMC
September 2016

Letter to the editor.

J Occup Environ Hyg 2015 ;12(6):D86-7

a Division of Pulmonary and Critical Care Medicine, Stanford Medicine, Stanford , California.

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http://dx.doi.org/10.1080/15459624.2015.1006639DOI Listing
March 2016

Measuring the sticking of mefenamic acid powders on stainless steel surface.

Int J Pharm 2015 Dec 9;496(2):407-13. Epub 2015 Oct 9.

Surfaces and Particle Engineering Laboratory (SPEL), Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK(1). Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2015.09.067DOI Listing
December 2015

Investigation into process-induced de-aggregation of cohesive micronised API particles.

Int J Pharm 2015 Sep 30;493(1-2):341-6. Epub 2015 Jul 30.

Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral CH46 1QW, UK.

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http://dx.doi.org/10.1016/j.ijpharm.2015.07.073DOI Listing
September 2015

Gene expression profiling in adipose tissue from growing broiler chickens.

Adipocyte 2014 Oct-Dec;3(4):297-303. Epub 2014 Dec 10.

Poultry Processing and Swine Physiology Research; Agricultural Research Service; USDA ; Athens, GA USA.

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http://dx.doi.org/10.4161/adip.29252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550682PMC
August 2015

The secondary drying and the fate of organic solvents for spray dried dispersion drug product.

Pharm Res 2015 May 17;32(5):1804-16. Epub 2014 Dec 17.

Drug Product Science & Technology, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, New Jersey, 08903, USA,

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http://dx.doi.org/10.1007/s11095-014-1577-yDOI Listing
May 2015

Application of image-based particle size and shape characterization systems in the development of small molecule pharmaceuticals.

J Pharm Sci 2015 May 17;104(5):1563-74. Epub 2015 Feb 17.

Drug Product Science and Technology, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

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http://dx.doi.org/10.1002/jps.24382DOI Listing
May 2015

Relationship between insulin resistance and tissue blood flow in preeclampsia.

J Hypertens 2015 May;33(5):1057-63

aDepartment of Obstetrics and Gynaecology, Kingston Hospital, Kingston upon Thames, Surrey bAcademic Department of Obstetrics and Gynaecology, Faculty of Medicine, Imperial College London, Chelsea & Westminster Hospital, London cSchool of Sports and Exercise Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1097/HJH.0000000000000494DOI Listing
May 2015

Fast coherent manipulation of three-electron states in a double quantum dot.

Nat Commun 2014 ;5:3020

Department of Physics, University of Wisconsin-Madison, 1150 University Ave., Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1038/ncomms4020DOI Listing
April 2015

The characterization of Salmonella enterica serotypes isolated from the scalder tank water of a commercial poultry processing plant: Recovery of a multidrug-resistant Heidelberg strain.

Poult Sci 2015 Mar 12;94(3):467-72. Epub 2015 Feb 12.

U.S. Department of Agriculture, Agricultural Research Service, Poultry Microbiological Safety and Processing Research Unit, 950 College Station Road, Athens, GA 30605.

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http://dx.doi.org/10.3382/ps/peu060DOI Listing
March 2015

Microwave-driven coherent operation of a semiconductor quantum dot charge qubit.

Nat Nanotechnol 2015 Mar 16;10(3):243-7. Epub 2015 Feb 16.

Department of Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1038/nnano.2014.336DOI Listing
March 2015

Development of a material sparing bulk density test comparable to a standard USP method for use in early development of API's.

AAPS PharmSciTech 2015 Feb 19;16(1):165-70. Epub 2014 Sep 19.

Drug Product Science and Technology, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK,

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http://dx.doi.org/10.1208/s12249-014-0215-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309802PMC
February 2015

A hybrid DNA extraction method for the qualitative and quantitative assessment of bacterial communities from poultry production samples.

J Vis Exp 2014 Dec 10(94). Epub 2014 Dec 10.

Department of Biological Sciences, Center for Microbial Genetics and Genomics, Northern Arizona University.

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http://dx.doi.org/10.3791/52161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396950PMC
December 2014

Effect of crystal habits on the surface energy and cohesion of crystalline powders.

Int J Pharm 2014 Sep 10;472(1-2):140-7. Epub 2014 Jun 10.

Surfaces and Particle Engineering Laboratory (SPEL), Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2014.06.014DOI Listing
September 2014

Subduction of the oceanic Hikurangi Plateau and its impact on the Kermadec arc.

Nat Commun 2014 Sep 17;5:4923. Epub 2014 Sep 17.

School of Geography, Environment and Earth Sciences, Victoria University of Wellington, PO Box 600, Wellington 6140, New Zealand.

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http://dx.doi.org/10.1038/ncomms5923DOI Listing
September 2014

Monitoring process induced attrition of drug substance particles within formulated blends.

Int J Pharm 2014 Aug 1;470(1-2):77-87. Epub 2014 May 1.

Drug Product Science & Technology, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral CH46 1QW, UK.

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http://dx.doi.org/10.1016/j.ijpharm.2014.04.028DOI Listing
August 2014

Quantum control and process tomography of a semiconductor quantum dot hybrid qubit.

Nature 2014 Jul;511(7507):70-4

Department of Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1038/nature13407DOI Listing
July 2014

Imaging dehydration kinetics of a channel hydrate form of the HIV-1 attachment inhibitor prodrug BMS-663068.

J Pharm Sci 2013 Dec 15;102(12):4375-83. Epub 2013 Oct 15.

Drug Product Science and Technology, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

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http://dx.doi.org/10.1002/jps.23747DOI Listing
December 2013

Powering transplant professional collaborations with Web and mobile apps.

Comput Inform Nurs 2013 Aug;31(8):351-5

Information Technology and Systems Center, University of Alabama in Huntsville, AL, USA.

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http://dx.doi.org/10.1097/CIN.0000000000000001DOI Listing
August 2013

Initiating collaboration among organ transplant professionals through Web portals and mobile applications.

Online J Issues Nurs 2013 May 13;18(2). Epub 2013 May 13.

College of Nursing at the University of Alabama in Huntsville, AL, USA.

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May 2013

Investigating the applicability of inverse gas chromatography to binary powdered systems: an application of surface heterogeneity profiles to understanding preferential probe-surface interactions.

Int J Pharm 2013 Mar 1;445(1-2):39-46. Epub 2013 Feb 1.

Material Science - Drug Product Science & Technology, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

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http://dx.doi.org/10.1016/j.ijpharm.2013.01.061DOI Listing
March 2013

Application of external lubrication during the roller compaction of adhesive pharmaceutical formulations.

Pharm Dev Technol 2013 Feb 20;18(1):246-56. Epub 2012 Jul 20.

School of Chemical Engineering, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.3109/10837450.2012.705299DOI Listing
February 2013

Pulse-gated quantum-dot hybrid qubit.

Phys Rev Lett 2012 Dec 20;109(25):250503. Epub 2012 Dec 20.

Department of Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1103/PhysRevLett.109.250503DOI Listing
December 2012

Fast hybrid silicon double-quantum-dot qubit.

Phys Rev Lett 2012 Apr 4;108(14):140503. Epub 2012 Apr 4.

Department of Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1103/PhysRevLett.108.140503DOI Listing
April 2012

An investigation into the impact of magnesium stearate on powder feeding during roller compaction.

Drug Dev Ind Pharm 2012 Jan 3;38(1):111-22. Epub 2011 Aug 3.

Department of Chemical Engineering, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.3109/03639045.2011.594802DOI Listing
January 2012

Surface energy analysis as a tool to probe the surface energy characteristics of micronized materials--a comparison with inverse gas chromatography.

Int J Pharm 2012 Jan 10;422(1-2):238-44. Epub 2011 Nov 10.

Drug Product Science & Technology/Materials Science, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

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http://dx.doi.org/10.1016/j.ijpharm.2011.11.002DOI Listing
January 2012

Investigation into the impact of sub-populations of agglomerates on the particle size distribution and flow properties of conventional microcrystalline cellulose grades.

Pharm Dev Technol 2011 Oct 21;16(5):542-8. Epub 2010 Jun 21.

Exploratory Biopharmaceutics R&D, Bristol-Myers Squibb, Moreton, Wirral, UK.

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http://www.tandfonline.com/doi/full/10.3109/10837450.2010.49
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http://dx.doi.org/10.3109/10837450.2010.495395DOI Listing
October 2011

Functional dilator capacity is independently associated with insulin sensitivity and age in central obesity and is not improved by high dose statin treatment.

Microcirculation 2011 Jan;18(1):74-84

Institute of Developmental Sciences, School of Medicine, University of Southampton, Southampton General Hospital (MP 887), Southampton, UK.

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http://dx.doi.org/10.1111/j.1549-8719.2010.00070.xDOI Listing
January 2011

Investigation into the degree of variability in the solid-state properties of common pharmaceutical excipients-anhydrous lactose.

AAPS PharmSciTech 2010 Dec 29;11(4):1552-7. Epub 2010 Oct 29.

Exploratory Biopharmaceutics R&D, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

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http://dx.doi.org/10.1208/s12249-010-9527-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011058PMC
December 2010

Monitoring and end-point prediction of a small scale wet granulation process using acoustic emission.

Pharm Dev Technol 2009 ;14(3):299-304

Biopharmaceutics R&D, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, UK.

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http://dx.doi.org/10.1080/10837450802603618DOI Listing
October 2010

Roller compaction: Application of an in-gap ribbon porosity calculation for the optimization of downstream granule flow and compactability characteristics.

Pharm Dev Technol 2009 Jul 22. Epub 2009 Jul 22.

Biopharmaceutics R&D, Bristol-Myers Squibb, Reeds Lane, Moreton, Wirral, England.

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http://dx.doi.org/10.1080/10837450903095342DOI Listing
July 2009

Risk of gastrointestinal cancers from inhalation and ingestion of asbestos.

Authors:
John Gamble

Regul Toxicol Pharmacol 2008 Oct 26;52(1 Suppl):S124-53. Epub 2007 Oct 26.

International Environmental Research Foundation, P.O. Box 3459, Grand Central Station, New York, NY 10163-3459, USA.

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http://dx.doi.org/10.1016/j.yrtph.2007.10.009DOI Listing
October 2008

An evaluation of the risks of lung cancer and mesothelioma from exposure to amphibole cleavage fragments.

Regul Toxicol Pharmacol 2008 Oct 22;52(1 Suppl):S154-86. Epub 2007 Oct 22.

International Environmental Research Foundation, Post Office Box 3459, Grand Central Station, New York, NY 10163-3459, USA.

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http://dx.doi.org/10.1016/j.yrtph.2007.09.020DOI Listing
October 2008

Rapporteur's Report Session 4: grunerite asbestos (amosite) and tremolite-ferroactinolite asbestos: risk of environmental mesothelioma.

Authors:
John F Gamble

Regul Toxicol Pharmacol 2008 Oct 7;52(1 Suppl):S121-3. Epub 2007 Nov 7.

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http://dx.doi.org/10.1016/j.yrtph.2007.10.015DOI Listing
October 2008

Review of the toxicology of mineral spirits.

Int J Toxicol 2008 Jan-Feb;27(1):97-165

ExxonMobil Biomedical Sciences, Annandale, New Jersey, USA.

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http://dx.doi.org/10.1080/10915810701876786DOI Listing
April 2008

Physician Assistant Program in North Carolina.

Authors:
John R Gamble

N C Med J 2007 Sep-Oct;68(5):379-80

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January 2008

Electron turbulence at nanoscale junctions.

Nano Lett 2007 Jun 22;7(6):1789-92. Epub 2007 May 22.

Department of Physics, University of California, San Diego, La Jolla, California 92093-0319, USA.

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http://dx.doi.org/10.1021/nl070935eDOI Listing
June 2007

Comments on the updated Harvard Six Cities study.

Am J Respir Crit Care Med 2006 Sep;174(6):722; author reply 722-4

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http://dx.doi.org/10.1164/ajrccm.174.6.722DOI Listing
September 2006

Eliminating racial and ethnic health diparities.

Authors:
John R Gamble

N C Med J 2005 Jan-Feb;66(1):79

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April 2005

A restrospective perspective.

J Appl Physiol (1985) 2005 Feb;98(2):762; author reply 762-3

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http://dx.doi.org/10.1152/japplphysiol.00773.2004DOI Listing
February 2005

Value-chain analysis of a rural health program: toward understanding the cost benefit of telemedicine applications.

Hosp Top 2004 ;82(1):10-7

Mitchell College of Business at the University of South Alabama, Mobile, USA.

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November 2004

Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice.

J Immunol 2004 Aug;173(3):1894-901

Division of Veterinary Clinical Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.173.3.1894DOI Listing
August 2004

Can lymphatic drainage be measured non-invasively in human limbs, using plethysmography?

Clin Sci (Lond) 2004 Jun;106(6):627-33

Clinic for Anaesthesiology, Ludwig-Maximilians University Munich, 81377 Munich, Germany.

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http://dx.doi.org/10.1042/CS20030314DOI Listing
June 2004

Relationship between silicosis and lung function.

Scand J Work Environ Health 2004 Feb;30(1):5-20

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http://dx.doi.org/10.5271/sjweh.760DOI Listing
February 2004

Garlic supplementation increases peripheral blood flow: a role for interleukin-6?

J Nutr Biochem 2004 Jan;15(1):30-6

Academic Department of Obstetrics and Gynaecology, Imperial College School of Medicine, Chelsea & Westminster Hospital, 369 Fulham Road, London, SW10 9NH, UK.

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January 2004

On primary care and access to care.

Authors:
John R Gamble

N C Med J 2002 Nov-Dec;63(6):315

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October 2003

Relationship between silicosis and smoking.

Scand J Work Environ Health 2003 Oct;29(5):329-36

University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.5271/sjweh.739DOI Listing
October 2003

More consequences of wait times.

Authors:
John R Gamble

Postgrad Med 2003 Aug;114(2):2; author reply 2

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August 2003

Microvascular permeability is related to circulating levels of tumour necrosis factor-alpha in pre-eclampsia.

Cardiovasc Res 2003 Apr;58(1):162-9

Department of Maternal and Fetal Medicine, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Chelsea and Westminster Hospital, London, UK.

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http://dx.doi.org/10.1016/s0008-6363(02)00844-1DOI Listing
April 2003

Realisation of a technique for the non-invasive, clinical assessment of microvascular parameters in man; the KM factor.

Authors:
John Gamble

Eur Surg Res 2002 Jan-Apr;34(1-2):114-23

School of Sport and Exercise Sciences, University of Birmingham, UK.

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http://dx.doi.org/10.1159/000048897DOI Listing
August 2002

Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction.

J Biol Chem 2002 Jan 2;277(3):1912-8. Epub 2001 Nov 2.

Laboratory of Lymphocyte Signalling and Development, Programme of Molecular Immunology, The Babraham Institute, Cambridge, CB2 4AT, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M108386200DOI Listing
January 2002