John G Gums

John G Gums

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John G Gums

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Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response.

Sci Rep 2019 Nov 21;9(1):17323. Epub 2019 Nov 21.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1038/s41598-019-53345-5DOI Listing
November 2019

Erenumab: A First-in-Class Monoclonal Antibody for Migraine Prevention.

Ann Pharmacother 2019 Sep 27;53(9):933-939. Epub 2019 Feb 27.

2 University of Florida College of Pharmacy, Gainesville, FL, USA.

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http://dx.doi.org/10.1177/1060028019835166DOI Listing
September 2019

Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta-Blockers in European Americans.

Clin Transl Sci 2019 Sep 4;12(5):497-504. Epub 2019 Jun 4.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1111/cts.12643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742943PMC
September 2019

Incident-to Billing for Pharmacists.

J Manag Care Spec Pharm 2018 Dec;24(12):1273-1276

1 University of Florida College of Pharmacy, Gainesville.

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https://www.jmcp.org/doi/10.18553/jmcp.2018.24.12.1273
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http://dx.doi.org/10.18553/jmcp.2018.24.12.1273DOI Listing
December 2018

Evaluation of SAMe-TTR Score on Predicting Success With Extended-Interval Warfarin Monitoring.

Ann Pharmacother 2018 11 1;52(11):1085-1090. Epub 2018 Jun 1.

3 College of Pharmacy, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1177/1060028018779774DOI Listing
November 2018

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.

BMC Med Genomics 2018 Jun 20;11(1):55. Epub 2018 Jun 20.

Center for Pharmacogenomics, Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, P.O.Box 100484, Gainesville, FL, 32610-0486, USA.

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http://dx.doi.org/10.1186/s12920-018-0370-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011347PMC
June 2018

Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses).

Circ Genom Precis Med 2018 04;11(4):e001854

Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics (C.W.M., O.M., A.C.C.S., N.M.E.R., M.K.-S., M.S., J.G.G., R.M.C.-D., Y.G., J.A.J.), Department of Pharmaceutical Outcomes and Policy (C.D.), Department of Pharmaceutics, College of Pharmacy (A.N.D., R.S.P.S.), Genetics & Genomics Graduate Program, Genetics Institute (A.C.C.S., Y.S.), Department of Biology, College of Liberal Arts and Sciences (W.M.), Department of Community Health and Family Medicine, College of Medicine (J.G.G.), and Division of Cardiovascular Medicine, Department of Medicine (R.M.C.-D., J.A.J.), University of Florida, Gainesville; School of Pharmacy, College of Health Professions, Pacific University, Hillsboro, OR (M.K.-S.); Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt (M.S.); Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.B.) and Division of Nephrology and Hypertension, Department of Medicine (S.T.T.), Mayo Clinic, Rochester, MN; Human Genetics Center, Institute of Molecular Medicine, University of Texas Health Science Center, Houston (E.B.); Section of Nephrology, Department of Medicine, University of Chicago, IL (A.B.C.); Department of Biomedical Informatics, Center for Pharmacogenomics (A.W.) and Department of Cancer Biology and Genetics, College of Medicine (W.S.), Ohio State University, Columbus; and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX (S.E.S.).

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http://dx.doi.org/10.1161/CIRCGEN.117.001854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901893PMC
April 2018

Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers.

J Am Heart Assoc 2018 02 24;7(5). Epub 2018 Feb 24.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL

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http://dx.doi.org/10.1161/JAHA.117.006463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866313PMC
February 2018

Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension.

J Clin Hypertens (Greenwich) 2017 Dec 21;19(12):1301-1308. Epub 2017 Sep 21.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1111/jch.13094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722670PMC
December 2017

The benefits of physician-pharmacist collaboration.

J Fam Pract 2017 Dec;66(12):E1-E8

Department of Pharmacotherapy and Translational Research, College of Pharmacy, and Department of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL, USA. Email:

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December 2017

Laboratory and Clinical Monitoring of Direct Acting Oral Anticoagulants: What Clinicians Need to Know.

Pharmacotherapy 2017 02 3;37(2):236-248. Epub 2017 Feb 3.

Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.

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http://dx.doi.org/10.1002/phar.1884DOI Listing
February 2017

The emergence and evolution of antimicrobial resistance: Impact on a global scale.

Bioorg Med Chem 2016 12 13;24(24):6440-6445. Epub 2016 Apr 13.

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, P.O. Box 100486, Gainesville, FL 32610, USA; Department of Community Health and Family Medicine, College of Medicine, University of Florida, 1707 North Main Street, Gainesville, FL 32609, USA.

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http://dx.doi.org/10.1016/j.bmc.2016.04.027DOI Listing
December 2016

Patient satisfaction with extended-interval warfarin monitoring.

J Thromb Thrombolysis 2016 Nov;42(4):486-93

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, P.O Box 100486, Gainesville, FL, 32610, USA.

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http://dx.doi.org/10.1007/s11239-016-1385-9DOI Listing
November 2016

A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.

Hypertension 2016 09 5;68(3):621-9. Epub 2016 Jul 5.

From the Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (M.H.S., Y.G., C.W.M., J.G.G., R.F.F., R.M.C.-D., J.A.J.) and Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine (T.J.G.), University of Florida, Gainesville; Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh (D.M.R., A.M.-R.); Department of Medicine, University of Maryland, Baltimore (A.L.B.); Department of Medicine, Emory University, Atlanta, GA (A.B.C.); Division of Nephrology and Hypertension, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN (S.T.T.); Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, (E.B.); Department of Molecular and Cellular Biology and Genome Center, University of California, Davis (O.F.); and Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC (R.K.-D.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982802PMC
September 2016

Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.

Metabolomics 2016 08 13;12(8). Epub 2016 Jul 13.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, PO Box 100486, Gainesville, FL 32610-0486, USA.

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http://dx.doi.org/10.1007/s11306-016-1076-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310671PMC
August 2016

Physician-pharmacist collaboration versus usual care for treatment-resistant hypertension.

J Am Soc Hypertens 2016 Apr 18;10(4):307-17. Epub 2016 Jan 18.

Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Iowa City, IA, USA; Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1016/j.jash.2016.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829453PMC
April 2016

Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers in Hypertensive African Americans.

Hypertension 2016 Mar 4;67(3):556-63. Epub 2016 Jan 4.

From the Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (Y.G., C.W.M., T.Y.L., J.G.G., R.M.C.-D., J.A.J.), Department of Community Health and Family Medicine, College of Medicine (K.H., S.O.F.S., R.W.C., J.G.G.), and Division of Cardiovascular Medicine, College of Medicine (R.M.C.-D., J.A.J.), University of Florida, Gainesville; Department of Epidemiology, Human Genetics & Environmental Sciences, Center for Human Genetics, University of Texas Health Science Center at Houston (Z.W., E.B.); Department of Medicine and Program in Personalized & Genomic Medicine, University of Maryland, Baltimore (A.L.B.); Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.B.) and Division of Nephrology and Hypertension (S.T.T.), Mayo Clinic, Rochester, MN; and Department of Medicine, University of Chicago, IL. (A.B.C.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752391PMC
March 2016

A novel simple method for determining CYP2D6 gene copy number and identifying allele(s) with duplication/multiplication.

PLoS One 2015 27;10(1):e0113808. Epub 2015 Jan 27.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113808PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308104PMC
January 2016

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.

J Hypertens 2015 Nov;33(11):2278-85

aDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, Florida USA bDepartment of Medicine and Program in Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA cDepartment of Medicine, University of Helsinki, and University Central Hospital of Helsinki, Helsinki, Finland dBHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK eDepartment of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA fInstitute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. gCollege of Medicine, Mayo Clinic Rochester, Rochester, Minnesota USA hCenter for Human Genetics, University of Texas at Houston, Houston, Texas, USA iRIKEN Center for Integrative Medical Sciences, Yokohama, Japan jSchool of Medicine, Emory University, Atlanta, Georgia, USA kDivision of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.

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http://pdfs.journals.lww.com/jhypertension/2015/11000/PTPRD_
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/HJH.0000000000000714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788379PMC
November 2015

Association of branched and aromatic amino acids levels with metabolic syndrome and impaired fasting glucose in hypertensive patients.

Metab Syndr Relat Disord 2015 Jun 9;13(5):195-202. Epub 2015 Feb 9.

1 Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida , College of Pharmacy, Gainesville, Florida.

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http://dx.doi.org/10.1089/met.2014.0132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519105PMC
June 2015

Feasibility of Extended-interval Follow-up for Patients Receiving Warfarin.

Cardiovasc Ther 2015 Jun;33(3):98-103

Department of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1111/1755-5922.12115DOI Listing
June 2015

Combining a GLP-1 receptor agonist and basal insulin: study evidence and practical considerations.

Drugs 2014 Dec;74(18):2141-52

Department of Pharmacotherapy and Translational Research, Department of Community Health and Family Medicine, Colleges of Pharmacy and Medicine, University of Florida, 1707 North Main Street, Gainesville, FL, 32609, USA,

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http://dx.doi.org/10.1007/s40265-014-0325-2DOI Listing
December 2014

Large-scale gene-centric analysis identifies polymorphisms for resistant hypertension.

J Am Heart Assoc 2014 Nov 10;3(6):e001398. Epub 2014 Nov 10.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL (C.W.M.D., Y.G., N.M.E.R., A.C.C., J.G.G., J.A.J., R.M.C.D.H.) Division of Cardiovascular Medicine, Department of Medicine, University of Florida, Gainesville, FL (C.J.P., J.A.J., R.M.C.D.H.).

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http://dx.doi.org/10.1161/JAHA.114.001398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338734PMC
November 2014

Alteration in fasting glucose after prolonged treatment with a thiazide diuretic.

Diabetes Res Clin Pract 2014 Jun 13;104(3):363-9. Epub 2014 Apr 13.

University of Florida College of Pharmacy, Gainesville, FL, United States; University of Florida College of Medicine, Gainesville, FL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2014.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074403PMC
June 2014

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

Authors:
Vinicius Tragante Michael R Barnes Santhi K Ganesh Matthew B Lanktree Wei Guo Nora Franceschini Erin N Smith Toby Johnson Michael V Holmes Sandosh Padmanabhan Konrad J Karczewski Berta Almoguera John Barnard Jens Baumert Yen-Pei Christy Chang Clara C Elbers Martin Farrall Mary E Fischer Tom R Gaunt Johannes M I H Gho Christian Gieger Anuj Goel Yan Gong Aaron Isaacs Marcus E Kleber Irene Mateo Leach Caitrin W McDonough Matthijs F L Meijs Olle Melander Christopher P Nelson Ilja M Nolte Nathan Pankratz Tom S Price Jonathan Shaffer Sonia Shah Maciej Tomaszewski Peter J van der Most Erik P A Van Iperen Judith M Vonk Kate Witkowska Caroline O L Wong Li Zhang Amber L Beitelshees Gerald S Berenson Deepak L Bhatt Morris Brown Amber Burt Rhonda M Cooper-DeHoff John M Connell Karen J Cruickshanks Sean P Curtis George Davey-Smith Christian Delles Ron T Gansevoort Xiuqing Guo Shen Haiqing Claire E Hastie Marten H Hofker G Kees Hovingh Daniel S Kim Susan A Kirkland Barbara E Klein Ronald Klein Yun R Li Steffi Maiwald Christopher Newton-Cheh Eoin T O'Brien N Charlotte Onland-Moret Walter Palmas Afshin Parsa Brenda W Penninx Mary Pettinger Ramachandran S Vasan Jane E Ranchalis Paul M Ridker Lynda M Rose Peter Sever Daichi Shimbo Laura Steele Ronald P Stolk Barbara Thorand Mieke D Trip Cornelia M van Duijn W Monique Verschuren Cisca Wijmenga Sharon Wyatt J Hunter Young Aeilko H Zwinderman Connie R Bezzina Eric Boerwinkle Juan P Casas Mark J Caulfield Aravinda Chakravarti Daniel I Chasman Karina W Davidson Pieter A Doevendans Anna F Dominiczak Garret A FitzGerald John G Gums Myriam Fornage Hakon Hakonarson Indrani Halder Hans L Hillege Thomas Illig Gail P Jarvik Julie A Johnson John J P Kastelein Wolfgang Koenig Meena Kumari Winfried März Sarah S Murray Jeffery R O'Connell Albertine J Oldehinkel James S Pankow Daniel J Rader Susan Redline Muredach P Reilly Eric E Schadt Kandice Kottke-Marchant Harold Snieder Michael Snyder Alice V Stanton Martin D Tobin André G Uitterlinden Pim van der Harst Yvonne T van der Schouw Nilesh J Samani Hugh Watkins Andrew D Johnson Alex P Reiner Xiaofeng Zhu Paul I W de Bakker Daniel Levy Folkert W Asselbergs Patricia B Munroe Brendan J Keating

Am J Hum Genet 2014 Mar 20;94(3):349-60. Epub 2014 Feb 20.

Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2013.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951943PMC
March 2014

Baseline predictors of central aortic blood pressure: a PEAR substudy.

J Am Soc Hypertens 2014 Mar 3;8(3):152-8. Epub 2014 Jan 3.

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA; Division of Medicine, Department of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1016/j.jash.2013.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959656PMC
March 2014

PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment.

Pharmacotherapy 2014 Feb 9;34(2):123-30. Epub 2013 Oct 9.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, Florida.

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http://dx.doi.org/10.1002/phar.1355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945213PMC
February 2014

Urate transporter gene SLC22A12 polymorphisms associated with obesity and metabolic syndrome in Caucasians with hypertension.

Kidney Blood Press Res 2012 8;35(6):477-82. Epub 2012 Jun 8.

College of Pharmacy and Center for Pharmacogenomics, University of Florida, Gainesville, Fla., USA. mshafiu @ rapadocs.com

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http://dx.doi.org/10.1159/000337370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480975PMC
October 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Authors:
Santhi K Ganesh Vinicius Tragante Wei Guo Yiran Guo Matthew B Lanktree Erin N Smith Toby Johnson Berta Almoguera Castillo John Barnard Jens Baumert Yen-Pei Christy Chang Clara C Elbers Martin Farrall Mary E Fischer Nora Franceschini Tom R Gaunt Johannes M I H Gho Christian Gieger Yan Gong Aaron Isaacs Marcus E Kleber Irene Mateo Leach Caitrin W McDonough Matthijs F L Meijs Olle Mellander Cliona M Molony Ilja M Nolte Sandosh Padmanabhan Tom S Price Ramakrishnan Rajagopalan Jonathan Shaffer Sonia Shah Haiqing Shen Nicole Soranzo Peter J van der Most Erik P A Van Iperen Jessica Van Setten Jessic A Van Setten Judith M Vonk Li Zhang Amber L Beitelshees Gerald S Berenson Deepak L Bhatt Jolanda M A Boer Eric Boerwinkle Ben Burkley Amber Burt Aravinda Chakravarti Wei Chen Rhonda M Cooper-Dehoff Sean P Curtis Albert Dreisbach David Duggan Georg B Ehret Richard R Fabsitz Myriam Fornage Ervin Fox Clement E Furlong Ron T Gansevoort Marten H Hofker G Kees Hovingh Susan A Kirkland Kandice Kottke-Marchant Abdullah Kutlar Andrea Z Lacroix Taimour Y Langaee Yun R Li Honghuang Lin Kiang Liu Steffi Maiwald Rainer Malik Gurunathan Murugesan Christopher Newton-Cheh Jeffery R O'Connell N Charlotte Onland-Moret Willem H Ouwehand Walter Palmas Brenda W Penninx Carl J Pepine Mary Pettinger Joseph F Polak Vasan S Ramachandran Jane Ranchalis Susan Redline Paul M Ridker Lynda M Rose Hubert Scharnag Nicholas J Schork Daichi Shimbo Alan R Shuldiner Sathanur R Srinivasan Ronald P Stolk Herman A Taylor Barbara Thorand Mieke D Trip Cornelia M van Duijn W Monique Verschuren Cisca Wijmenga Bernhard R Winkelmann Sharon Wyatt J Hunter Young Bernhard O Boehm Mark J Caulfield Daniel I Chasman Karina W Davidson Pieter A Doevendans Garret A Fitzgerald John G Gums Hakon Hakonarson Hans L Hillege Thomas Illig Gail P Jarvik Julie A Johnson John J P Kastelein Wolfgang Koenig Winfried März Braxton D Mitchell Sarah S Murray Albertine J Oldehinkel Daniel J Rader Muredach P Reilly Alex P Reiner Eric E Schadt Roy L Silverstein Harold Snieder Alice V Stanton André G Uitterlinden Pim van der Harst Yvonne T van der Schouw Nilesh J Samani Andrew D Johnson Patricia B Munroe Paul I W de Bakker Xiaofeng Zhu Daniel Levy Brendan J Keating Folkert W Asselbergs

Hum Mol Genet 2013 Apr 8;22(8):1663-78. Epub 2013 Jan 8.

Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, MI, USA.

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http://hmg.oxfordjournals.org/content/22/8/1663.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds555
Publisher Site
http://dx.doi.org/10.1093/hmg/dds555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657476PMC
April 2013

Changing the direction of clinical pharmacy outside the United States: time to step up.

Authors:
John G Gums

Pharmacotherapy 2013 Feb;33(2):122-5

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http://dx.doi.org/10.1002/phar.1247DOI Listing
February 2013

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Authors:
Folkert W Asselbergs Yiran Guo Erik P A van Iperen Suthesh Sivapalaratnam Vinicius Tragante Matthew B Lanktree Leslie A Lange Berta Almoguera Yolande E Appelman John Barnard Jens Baumert Amber L Beitelshees Tushar R Bhangale Yii-Der Ida Chen Tom R Gaunt Yan Gong Jemma C Hopewell Toby Johnson Marcus E Kleber Taimour Y Langaee Mingyao Li Yun R Li Kiang Liu Caitrin W McDonough Matthijs F L Meijs Rita P S Middelberg Kiran Musunuru Christopher P Nelson Jeffery R O'Connell Sandosh Padmanabhan James S Pankow Nathan Pankratz Suzanne Rafelt Ramakrishnan Rajagopalan Simon P R Romaine Nicholas J Schork Jonathan Shaffer Haiqing Shen Erin N Smith Sam E Tischfield Peter J van der Most Jana V van Vliet-Ostaptchouk Niek Verweij Kelly A Volcik Li Zhang Kent R Bailey Kristian M Bailey Florianne Bauer Jolanda M A Boer Peter S Braund Amber Burt Paul R Burton Sarah G Buxbaum Wei Chen Rhonda M Cooper-Dehoff L Adrienne Cupples Jonas S deJong Christian Delles David Duggan Myriam Fornage Clement E Furlong Nicole Glazer John G Gums Claire Hastie Michael V Holmes Thomas Illig Susan A Kirkland Mika Kivimaki Ronald Klein Barbara E Klein Charles Kooperberg Kandice Kottke-Marchant Meena Kumari Andrea Z LaCroix Laya Mallela Gurunathan Murugesan Jose Ordovas Willem H Ouwehand Wendy S Post Richa Saxena Hubert Scharnagl Pamela J Schreiner Tina Shah Denis C Shields Daichi Shimbo Sathanur R Srinivasan Ronald P Stolk Daniel I Swerdlow Herman A Taylor Eric J Topol Elina Toskala Joost L van Pelt Jessica van Setten Salim Yusuf John C Whittaker A H Zwinderman Sonia S Anand Anthony J Balmforth Gerald S Berenson Connie R Bezzina Bernhard O Boehm Eric Boerwinkle Juan P Casas Mark J Caulfield Robert Clarke John M Connell Karen J Cruickshanks Karina W Davidson Ian N M Day Paul I W de Bakker Pieter A Doevendans Anna F Dominiczak Alistair S Hall Catharina A Hartman Christian Hengstenberg Hans L Hillege Marten H Hofker Steve E Humphries Gail P Jarvik Julie A Johnson Bernhard M Kaess Sekar Kathiresan Wolfgang Koenig Debbie A Lawlor Winfried März Olle Melander Braxton D Mitchell Grant W Montgomery Patricia B Munroe Sarah S Murray Stephen J Newhouse N Charlotte Onland-Moret Neil Poulter Bruce Psaty Susan Redline Stephen S Rich Jerome I Rotter Heribert Schunkert Peter Sever Alan R Shuldiner Roy L Silverstein Alice Stanton Barbara Thorand Mieke D Trip Michael Y Tsai Pim van der Harst Ellen van der Schoot Yvonne T van der Schouw W M Monique Verschuren Hugh Watkins Arthur A M Wilde Bruce H R Wolffenbuttel John B Whitfield G Kees Hovingh Christie M Ballantyne Cisca Wijmenga Muredach P Reilly Nicholas G Martin James G Wilson Daniel J Rader Nilesh J Samani Alex P Reiner Robert A Hegele John J P Kastelein Aroon D Hingorani Philippa J Talmud Hakon Hakonarson Clara C Elbers Brendan J Keating Fotios Drenos

Am J Hum Genet 2012 Nov 11;91(5):823-38. Epub 2012 Oct 11.

Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2012.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487124PMC
November 2012

G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension.

Hypertension 2012 Oct 4;60(4):957-64. Epub 2012 Sep 4.

Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, 1600 SW Archer Rd, Room PG-22, Box 100486, Gainesville, FL 32610-0486, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.198721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462355PMC
October 2012

Intranasal fentanyl spray: a novel dosage form for the treatment of breakthrough cancer pain.

Ann Pharmacother 2012 Oct 25;46(10):1382-91. Epub 2012 Sep 25.

Department of Pharmacotherapy and Translational Research, Colleges of Pharmacy and Medicine, University of Florida, Gainesville, USA.

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http://dx.doi.org/10.1345/aph.1R069DOI Listing
October 2012

Dabigatran etexilate: a novel oral thrombin inhibitor for thromboembolic disease.

Ann Pharmacother 2011 May 3;45(5):603-14. Epub 2011 May 3.

University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1345/aph.1P644DOI Listing
May 2011

Place of dabigatran in contemporary pharmacotherapy.

Authors:
John G Gums

Pharmacotherapy 2011 Apr;31(4):335-7

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http://dx.doi.org/10.1592/phco.31.4.335DOI Listing
April 2011

Antivirals for influenza: strategies for use in pediatrics.

Paediatr Drugs 2010 Oct;12(5):285-99

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.2165/11532530-000000000-00000DOI Listing
October 2010

Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide.

Pharmacogenet Genomics 2010 Aug;20(8):516-9

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida 32610, USA.

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https://insights.ovid.com/crossref?an=01213011-201008000-000
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http://dx.doi.org/10.1097/FPC.0b013e32833b5958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922977PMC
August 2010

Combination antihypertensive treatment: is initiation order important?

J Clin Hypertens (Greenwich) 2010 Aug;12(8):565-7

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http://dx.doi.org/10.1111/j.1751-7176.2010.00319.xDOI Listing
August 2010

You don't know what you've got till it's gone.

Authors:
John G Gums

Pharmacotherapy 2010 Mar;30(3):221-3

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http://dx.doi.org/10.1592/phco.30.3.221DOI Listing
March 2010

Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications.

Hypertension 2010 Jan 16;55(1):61-8. Epub 2009 Nov 16.

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1600 SW Archer Rd, Box 100486, Gainesville, FL 32610-0486, USA.

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.109.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.139592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811061PMC
January 2010

Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.

Expert Opin Drug Metab Toxicol 2009 Jul;5(7):813-22

University of Florida, Colleges of Pharmacy and Medicine, Departments of Pharmacotherapy & Translational Research and Community Health & Family Medicine, Gainesville, FL 32610-0486, USA.

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http://dx.doi.org/10.1517/17425250903044967DOI Listing
July 2009

Ceftobiprole: an extended-spectrum anti-methicillin-resistant Staphylococcus aureus cephalosporin.

Ann Pharmacother 2008 Jun 13;42(6):806-16. Epub 2008 May 13.

Departments of Pharmacy Practice and Family Medicine, University of Florida, Gainesville, FL 32601, USA.

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http://dx.doi.org/10.1345/aph.1L016DOI Listing
June 2008

Oseltamivir and influenza-related complications, hospitalization and healthcare expenditure in healthy adults and children.

Expert Opin Pharmacother 2008 Feb;9(2):151-61

Department of Pharmacy Practice, University of Florida, Gainesville, Florida 32601, USA.

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http://dx.doi.org/10.1517/14656566.9.2.151DOI Listing
February 2008

Differences between ceftriaxone and cefotaxime: microbiological inconsistencies.

Ann Pharmacother 2008 Jan 19;42(1):71-9. Epub 2007 Dec 19.

Department of Pharmacy Practice, University of Florida, Gainesville, FL 32601, USA.

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http://journals.sagepub.com/doi/10.1345/aph.1H620
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http://dx.doi.org/10.1345/aph.1H620DOI Listing
January 2008

Formation of a primary care pharmacist practice-based research network.

Am J Health Syst Pharm 2007 Oct;64(19):2044-9

Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29406, USA.

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http://www.ajhp.org/cgi/doi/10.2146/ajhp060650
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http://dx.doi.org/10.2146/ajhp060650DOI Listing
October 2007

Antimicrobial resistance in 11 hospitals in Puerto Rico: results of an antimicrobial resistance management (ARM) program.

P R Health Sci J 2007 Sep;26(3):181-9

University of Florida, Gainesville, Florida 32601, USA.

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September 2007

Newer agents for the management of overactive bladder.

Am Fam Physician 2006 Dec;74(12):2061-8

University of Florida, Gainesville, Florida, USA.

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December 2006

Optimal pharmacological therapy for community-acquired pneumonia: the role of dual antibacterial therapy.

Drugs 2005 ;65(14):1949-71

Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, Florida 32601, USA.

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http://dx.doi.org/10.2165/00003495-200565140-00004DOI Listing
January 2006

Can the renin-angiotensin system protect against stroke? A focus on angiotensin II receptor blockers.

Pharmacotherapy 2005 Apr;25(4):531-9

Department of Pharmacy Practice, College of Pharmacy, College of Medicine, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1592/phco.25.4.531.61022DOI Listing
April 2005

Angiotensin receptor blockers versus ACE inhibitors: prevention of death and myocardial infarction in high-risk populations.

Ann Pharmacother 2005 Mar 8;39(3):470-80. Epub 2005 Feb 8.

Department of Pharmacy Practice, College of Pharmacy, University of Florida, 625 SW 4th Avenue, Gainesville, FL 32601-6430, USA.

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http://dx.doi.org/10.1345/aph.1E478DOI Listing
March 2005

The changing face of antibiotic prescribing: the mutant selection window.

Ann Pharmacother 2004 Oct 31;38(10):1675-82. Epub 2004 Aug 31.

Internal Medicine Resident, North Florida/South Georgia Veterans Affairs Health-System, Gainesville, FL, USA.

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http://dx.doi.org/10.1345/aph.1E041DOI Listing
October 2004

Magnesium in cardiovascular and other disorders.

Authors:
John G Gums

Am J Health Syst Pharm 2004 Aug;61(15):1569-76

Department of Pharmacy Practice and Community Health and Family Medicine, University of Florida, Gainesville, FL 32601, USA.

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http://dx.doi.org/10.1093/ajhp/61.15.1569DOI Listing
August 2004

Redefining appropriate use of antibiotics.

Authors:
John G Gums

Am Fam Physician 2004 Jan;69(1):35, 39-40

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January 2004

Monitoring pulmonary function in asthma and COPD: point-of-care testing.

Ann Pharmacother 2004 Jan;38(1):126-33

Department of Pharmacy Practice, University of Florida, Gainesville, FL 32601, USA.

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http://journals.sagepub.com/doi/10.1345/aph.1D230
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http://dx.doi.org/10.1345/aph.1D230DOI Listing
January 2004

Tezosentan in the treatment of acute heart failure.

Ann Pharmacother 2003 Dec;37(12):1877-83

Departments of Pharmacy Practice and Family Medicine, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1345/aph.1D080DOI Listing
December 2003

NCCLS perspectives in changing susceptibility breakpoints for antimicrobial drugs.

Authors:
John G Gums

Int J Antimicrob Agents 2003 Oct;22 Suppl 1:S3-13; discussion S25-6

College of Pharmacy and Medicine, Departments of Pharmacy Practice and Community Health and Family Medicine, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1016/j.ijantimicag.2003.08.005DOI Listing
October 2003

Assessing the impact of antimicrobial resistance.

Authors:
John G Gums

Am J Health Syst Pharm 2002 Apr;59(8 Suppl 3):S4-6

Departments of Pharmacy Practice and Family Medicine, University of Florida, 625 Southwest Fourth Avenue, Gainesville, FL 32601, USA.

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http://dx.doi.org/10.1093/ajhp/59.suppl_3.S4DOI Listing
April 2002

Infectious vaginitis.

Postgrad Med 1994 Dec;96(6):85-98

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http://dx.doi.org/10.1080/00325481.1994.11945924DOI Listing
December 1994

The Elderly Diabetic Patient With Hypertension: Guidelines for Prescribing Antihypertensive Therapy.

Am J Geriatr Cardiol 1994 Oct;3(5):37-46

Albany College of Pharmacy, Albany, NY.

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October 1994