Publications by authors named "John F Valliant"

89 Publications

Imidazole fused phenanthroline (PIP) ligands for the preparation of multimodal Re(I) and Tc(I) probes.

Dalton Trans 2020 Nov;49(42):14826-14836

Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4 M1, Canada.

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November 2020

Evaluation of a Ga-Labeled DOTA-Tetrazine as a PET Alternative to In-SPECT Pretargeted Imaging.

Molecules 2020 Jan 22;25(3). Epub 2020 Jan 22.

Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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January 2020

Improved radiosynthesis and preliminary in vivo evaluation of the C-labeled tetrazine [C]AE-1 for pretargeted PET imaging.

Bioorg Med Chem Lett 2019 04 13;29(8):986-990. Epub 2019 Feb 13.

Department for Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark; Department of Clinical Physiology, Nuclear Medicine and PET, University Hospital Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. Electronic address:

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April 2019

In vivo Biodistribution of Radiolabeled Acoustic Protein Nanostructures.

Mol Imaging Biol 2018 04;20(2):230-239

Sunnybrook Research Institute, 2075 Bayview Avenue, Room S640, Toronto, ON, M4N 3M5, Canada.

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April 2018

F-Labeled perfluorocarbon droplets for positron emission tomography imaging.

Nucl Med Biol 2017 Nov 12;54:27-33. Epub 2017 Jul 12.

Department of Medical Imaging, University of Toronto, Toronto, ON, Canada; Department of Materials Science and Engineering, University of Toronto, Toronto, ON, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada. Electronic address:

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November 2017

[F]-DCFPyL Positron Emission Tomography/Magnetic Resonance Imaging for Localization of Dominant Intraprostatic Foci: First Experience.

Eur Urol Focus 2018 09 26;4(5):702-706. Epub 2016 Oct 26.

Department of Oncology, Western University and Lawson Health Research Institute, London, Canada; Department of Medical Biophysics, Western University and Lawson Health Research Institute, London, Canada.

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September 2018

Targeting Prostate-Specific Membrane Antigen (PSMA) with F-18-Labeled Compounds: the Influence of Prosthetic Groups on Tumor Uptake and Clearance Profile.

Mol Imaging Biol 2017 12;19(6):923-932

Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, AB, T6G 2X4, Canada.

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December 2017

Ga-labeled deferoxamine derivatives for imaging bacterial infection: Preparation and screening of functionalized siderophore complexes.

Nucl Med Biol 2017 Sep 1;52:32-41. Epub 2017 Jun 1.

Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada; Department of Biochemistry & Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada. Electronic address:

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September 2017

Technetium(I) Complexes of Bathophenanthrolinedisulfonic Acid.

Inorg Chem 2017 Mar 15;56(5):2958-2965. Epub 2017 Feb 15.

Department of Chemistry and Chemical Biology and ‡Centre for Probe Development and Commercialization, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada.

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March 2017

Preparation of an F-Labeled Hydrocyanine Dye as a Multimodal Probe for Reactive Oxygen Species.

Chemistry 2017 01 29;23(2):254-258. Epub 2016 Nov 29.

Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4M1, Canada.

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January 2017

A Bridge Not Too Far: Linking Disciplines Through Molecular Imaging Probes.

Authors:
John F Valliant

J Nucl Med Technol 2016 Sep;44(3):173-83

Departments of Chemistry and Medical Physics and Centre for Probe Development and Commercialization, McMaster University, Hamilton, Ontario, Canada

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September 2016

Synthesis of Polyester Dendritic Scaffolds for Biomedical Applications.

Macromol Biosci 2016 10 4;16(10):1475-1484. Epub 2016 Jul 4.

Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, L8S 4M1, Canada.

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October 2016

Automated synthesis of [(18)F]DCFPyL via direct radiofluorination and validation in preclinical prostate cancer models.

EJNMMI Res 2016 Dec 4;6(1):40. Epub 2016 May 4.

Department of Oncology, University of Alberta, 11560 University Avenue, Edmonton, AB, T6G 1Z2, Canada.

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December 2016

Imaging Biomarkers in Immunotherapy.

Biomark Cancer 2016 25;8(Suppl 2):1-13. Epub 2016 Feb 25.

Department of Radiology, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.

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March 2016

Design and synthesis of [(125)I]Pyricoxib: A novel (125)I-labeled cyclooxygenase-2 (COX-2) inhibitors.

Bioorg Med Chem Lett 2016 Mar 11;26(6):1516-1520. Epub 2016 Feb 11.

Department of Oncology, University of Alberta, Canada; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Canada. Electronic address:

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March 2016

Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That Target Prostate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy.

J Med Chem 2016 Mar 3;59(6):2660-73. Epub 2016 Mar 3.

Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada.

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March 2016

(125)I-Tetrazines and Inverse-Electron-Demand Diels-Alder Chemistry: A Convenient Radioiodination Strategy for Biomolecule Labeling, Screening, and Biodistribution Studies.

Bioconjug Chem 2016 Jan 5;27(1):207-16. Epub 2016 Jan 5.

Department of Chemistry and Chemical Biology and ‡Centre for Probe Development and Commercialization, McMaster University , 1280 Main Street West, Hamilton, Ontario, Canada L8S 4M1.

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January 2016

Synthesis, Radiolabeling, and In Vivo Imaging of PEGylated High-Generation Polyester Dendrimers.

Biomacromolecules 2015 Sep 31;16(9):3033-41. Epub 2015 Aug 31.

Department of Chemistry and Chemical Biology, McMaster University , Hamilton, Ontario L8S 4M1, Canada.

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September 2015

Imidazole-based [2 + 1] Re(I)/99mTc(I) complexes as isostructural nuclear and optical probes.

Inorg Chem 2015 Feb 29;54(4):1728-36. Epub 2015 Jan 29.

Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada.

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February 2015

(125)I-Labelled 2-Iodoestrone-3-sulfate: synthesis, characterization and OATP mediated transport studies in hormone dependent and independent breast cancer cells.

Nucl Med Biol 2015 Mar 8;42(3):274-82. Epub 2014 Nov 8.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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March 2015

Synthesis and evaluation of radioiodinated acyloxymethyl ketones as activity-based probes for cathepsin B.

J Med Chem 2014 Nov 14;57(22):9564-77. Epub 2014 Nov 14.

Department of Chemistry & Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada.

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November 2014