John F Keaney

John F Keaney

UNVERIFIED PROFILE

Are you John F Keaney?   Register this Author

Register author
John F Keaney

John F Keaney

Publications by authors named "John F Keaney"

Are you John F Keaney?   Register this Author

100Publications

1876Reads

35Profile Views

Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis.

Nat Commun 2019 09 17;10(1):4223. Epub 2019 Sep 17.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01655, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-11982-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748991PMC
September 2019

JNK and cardiometabolic dysfunction.

Biosci Rep 2019 Jul 18;39(7). Epub 2019 Jul 18.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BSR20190267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639461PMC
July 2019

Short-term exposure to ambient air pollution and circulating biomarkers of endothelial cell activation: The Framingham Heart Study.

Environ Res 2019 04 28;171:36-43. Epub 2018 Oct 28.

Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA 02115, United States; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00139351183056
Publisher Site
http://dx.doi.org/10.1016/j.envres.2018.10.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478022PMC
April 2019

Mitral Valve Repair Versus Replacement in Elderly With Degenerative Disease: Analysis of the STS Adult Cardiac Surgery Database.

Ann Thorac Surg 2019 03 26;107(3):747-753. Epub 2018 Oct 26.

Division of Cardiac Surgery, Department of Surgery, University of Massachusetts Medical School, Worcester, Massachusetts; Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2018.09.018DOI Listing
March 2019

VITAL Signs for Dietary Supplementation to Prevent Cancer and Heart Disease.

N Engl J Med 2019 01 10;380(1):91-93. Epub 2018 Nov 10.

From the University of Massachusetts Medical School, Worcester (J.F.K.); and the Maine Medical Center Research Institute, Scarborough (C.J.R.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe1814933DOI Listing
January 2019

Hdac3 regulates lymphovenous and lymphatic valve formation.

J Clin Invest 2017 Nov 16;127(11):4193-4206. Epub 2017 Oct 16.

Division of Cardiovascular Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI92852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663362PMC
November 2017

Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study.

Arterioscler Thromb Vasc Biol 2017 09 27;37(9):1793-1800. Epub 2017 Jul 27.

From the Departments of Epidemiology (W.L., K.S.D., E.H.W., J.D.S., M.A.M.), Environmental Health (J.D.S., P.K., D.R.G.), and Biostatistics (B.A.C.), Harvard T.H. Chan School of Public Health, Boston, MA; Cardiovascular Epidemiology Research Unit, Division of Cardiology (W.L., K.S.D., E.H.W., P.L.L., M.A.M.) and Division of Pulmonary, Critical Care and Sleep Medicine (M.B.R.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (P.L.L.); Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (D.R.G.); Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester (J.F.K.); National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, MA (R.S.V., E.J.B.); Preventive Medicine and Cardiology Sections, Department of Medicine, Boston University School of Medicine, MA (R.S.V., E.J.B.); and Department of Epidemiology, Boston University School of Public Health, MA (R.S.V., E.J.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.117.309799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570664PMC
September 2017

CHIP-ping Away at Atherosclerosis.

Authors:
John F Keaney

N Engl J Med 2017 07 21;377(2):184-185. Epub 2017 Jun 21.

From the University of Massachusetts Medical School, Worcester.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe1706173DOI Listing
July 2017

Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression.

Sci Rep 2017 05 17;7(1):2013. Epub 2017 May 17.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-01879-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435730PMC
May 2017

PGC-1α dictates endothelial function through regulation of eNOS expression.

Sci Rep 2016 12 2;6:38210. Epub 2016 Dec 2.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep38210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133545PMC
December 2016

Common Statistical Pitfalls in Basic Science Research.

J Am Heart Assoc 2016 09 29;5(10). Epub 2016 Sep 29.

Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.116.004142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121512PMC
September 2016

Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development.

Elife 2016 08 9;5. Epub 2016 Aug 9.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.18414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999312PMC
August 2016

Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling.

Nitric Oxide 2016 05 14;55-56:45-53. Epub 2016 Mar 14.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.niox.2016.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860108PMC
May 2016

Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation.

J Am Heart Assoc 2016 05 4;5(5). Epub 2016 May 4.

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA Division of Endocrinology, Brigham and Women's Hospital, Boston, MA.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/JAHA.115.002936
Publisher Site
http://dx.doi.org/10.1161/JAHA.115.002936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889173PMC
May 2016

The molecular basis of the genesis of basal tone in internal anal sphincter.

Nat Commun 2016 Apr 22;7:11358. Epub 2016 Apr 22.

State Key Laboratory of Pharmaceutical Biotechnology and Model Animal Research Center and MOE Key Laboratory of Model Animal for Disease Study, Nanjing University, Nanjing 210061, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms11358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844698PMC
April 2016

Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study.

J Am Heart Assoc 2016 04 28;5(5). Epub 2016 Apr 28.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA Cardiovascular Epidemiology Research Unit, Department of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.115.002742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889166PMC
April 2016

Reactive oxygen species in endothelial function - from disease to adaptation - .

Circ J 2015 18;79(6):1145-55. Epub 2015 May 18.

University of Massachusetts Medical School.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1253/circj.CJ-15-0464DOI Listing
March 2016

Postmenopausal Hormone Therapy and Atherosclerosis--Time Is of the Essence.

N Engl J Med 2016 Mar;374(13):1279-80

From the University of Massachusetts Medical School, Worcester (J.F.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe1602846DOI Listing
March 2016

Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study.

J Am Heart Assoc 2016 Feb 29;5(3):e002545. Epub 2016 Feb 29.

National Heart, Lung, and Blood Institute's Division of Intramural Research, The Framingham Heart Study, and the Population Studies Branch, Framingham, MA Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.115.002545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943240PMC
February 2016

Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions.

Free Radic Biol Med 2015 Dec 10;89:1-7. Epub 2015 Jul 10.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08915849150032
Publisher Site
http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783146PMC
December 2015

Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications.

Eur Heart J 2015 Oct 4;36(38):2555-64. Epub 2015 Jul 4.

2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Langenbeckstrasse 1, Mainz 55131, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/eurheartj/ehv305DOI Listing
October 2015

Creating and Maintaining a Successful Service Line in an Academic Medical Center at the Dawn of Value-Based Care: Lessons Learned From the Heart and Vascular Service Line at UMass Memorial Health Care.

Acad Med 2015 Oct;90(10):1340-6

R.A. Phillips is executive vice president and chief medical officer, Houston Methodist, Houston, Texas, and president and chief executive officer, Houston Methodist Specialty Physician Group, Houston, Texas. At the time this article was written, he was physician executive director, Heart and Vascular Center of Excellence, UMass Memorial Medical Center, professor of medicine, University of Massachusetts Medical School, and faculty member, Clinical and Population Health Research PhD Program, UMass Graduate School of Biological Sciences, Worcester, Massachusetts.J. Cyr is senior vice president, Heart and Vascular Center of Excellence, UMass Memorial Medical Center and University of Massachusetts Medical School, Worcester, Massachusetts.J.F. Keaney Jr is chief of cardiovascular medicine and medical director, Heart and Vascular Center of Excellence, UMass Memorial Medical Center, and professor of medicine, University of Massachusetts Medical School, Worcester, Massachusetts.L.M. Messina is chief of vascular and endovascular surgery, UMass Memorial Medical Center, and professor of surgery, University of Massachusetts Medical School, Worcester, Massachusetts.T.E. Meyer is director, Advanced Heart Failure Program, UMass Memorial Medical Center, clinical chief of cardiovascular medicine, and professor of medicine, University of Massachusetts Medical School, Worcester, Massachusetts.S.K.C. Tam is executive director, Cardiovascular Services, Steward Health Care System, Boston, Massachusetts. At the time this article was written, he was chief of cardiothoracic surgery, UMass Memorial Medical Center, and associate professor of surgery, University of Massachusetts Medical School, Worcester, Massachusetts.K. Korenda is senior director, Heart and Vascular Center of Excellence, UMass Memorial Medical Center, Worcester, Massachusetts.M. Darrigo is executive director for heart and vascular services, Saint Vincent Hospital, Worcester, Massachusetts, and MetroWest Medical Center, Framin

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ACM.0000000000000839DOI Listing
October 2015

Proof That Lower Is Better--LDL Cholesterol and IMPROVE-IT.

N Engl J Med 2015 Jun 3;372(25):2448-50. Epub 2015 Jun 3.

From the University of Massachusetts Medical School, Worcester, MA (J.F.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe1507041DOI Listing
June 2015

Balancing the risks and benefits of dual platelet inhibition.

Authors:
John F Keaney

N Engl J Med 2015 May 14;372(19):1854-6. Epub 2015 Mar 14.

From the Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe1502137DOI Listing
May 2015

Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study).

Heart Rhythm 2015 Jan 9;12(1):3-10. Epub 2014 Oct 9.

Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2014.09.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277933PMC
January 2015

Joseph A. Vita, MD, 1956-2014.

Circulation 2015 Jan;131(4):432-3

From the UMass Medical School and UMass Memorial Medical Center, Worcester, MA (J.F.K.); and Harvard Medical School and Brigham and Women's Hospital, Boston, MA (J.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.114.014964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323562PMC
January 2015

Joseph A. Vita, MD, 1956-2014.

J Am Heart Assoc 2015 Jan 26;4(1):e001778. Epub 2015 Jan 26.

Harvard Medical School and Brigham and Women's Hospital, Boston, MA (J.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.115.001778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330084PMC
January 2015

Association of exhaled carbon monoxide with subclinical cardiovascular disease and their conjoint impact on the incidence of cardiovascular outcomes.

Eur Heart J 2014 Nov 25;35(42):2980-7. Epub 2014 Feb 25.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA Sections of Preventive Medicine, Boston University School of Medicine, Boston, MA, USA Department of Cardiology, Boston University School of Medicine, Boston, MA, USA Department of Epidemiology, Boston University School of Medicine, Boston, MA, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/eurheartj/article-lookup/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/eurheartj/ehu052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271053PMC
November 2014

The new cholesterol treatment guidelines.

N Engl J Med 2014 05;370(20):1957

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1403438DOI Listing
May 2014

A pragmatic view of the new cholesterol treatment guidelines.

N Engl J Med 2014 Jan 27;370(3):275-8. Epub 2013 Nov 27.

From the University of Massachusetts Medical School, Worcester (J.F.K.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMms1314569DOI Listing
January 2014

Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk.

Arterioscler Thromb Vasc Biol 2013 Nov 22;33(11):2666-73. Epub 2013 Aug 22.

From the National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA (D.D.M., K.T., M.G.L., J.E.F.); Cardiology Division, Department of Medicine (D.D.M, L.M.B., K.T., J.F.K., J.E.F.) and Epidemiology Division, Department of Quantitative Health Sciences (D.D.M, E.M.), University of Massachusetts Medical School, Worcester, MA; Section of Cardiovascular Medicine, Department of Medicine (E.J.B.) and Department of Mathematics and Statistics (M.G.L.), Boston University, Boston, MA; Preventive Medicine Section, Department of Medicine, Boston University School of Medicine, Boston, MA (E.J.B.); and Department of Epidemiology (E.J.B.) and Department of Biostatistics (M.G.L.), Boston University School of Public Health, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.112.301112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289138PMC
November 2013

Circulating Cell and Plasma microRNA Profiles Differ between Non-ST-Segment and ST-Segment-Elevation Myocardial Infarction.

Fam Med Med Sci Res 2013 Oct;2(2):108

Cardiac Electrophysiology Section, Cardiovascular Medicine Division, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA ; Department of Quantitative Health Sciences, University of Massachusetts, Medical School, Worcester, MA, USA ; Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4172/2327-4972.1000108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890357PMC
October 2013

P2Y12 inhibition in patients with NSTEMI--can later be better?

Authors:
John F Keaney

N Engl J Med 2013 Sep 1;369(11):1056-7. Epub 2013 Sep 1.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMe1308820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872834PMC
September 2013

Evolving concepts of oxidative stress and reactive oxygen species in cardiovascular disease.

Curr Atheroscler Rep 2012 Oct;14(5):476-83

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue N., S3-851, Worcester, MA 01655, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11883-012-0266-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872835PMC
October 2012

Nicotine: linking smoking to abdominal aneurysms.

Nat Med 2012 Jun 6;18(6):856-8. Epub 2012 Jun 6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.2714DOI Listing
June 2012

Immune modulation of atherosclerosis.

Authors:
John F Keaney

Circulation 2011 Nov;124(22):e559-60

Division of Cardiovascular Medicine, UMass Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.111.074096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233261PMC
November 2011

Reactive oxygen species in cardiovascular disease.

Free Radic Biol Med 2011 Sep 15;51(5):978-92. Epub 2011 May 15.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2011.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156326PMC
September 2011

NADPH oxidase 4 promotes endothelial angiogenesis through endothelial nitric oxide synthase activation.

Circulation 2011 Aug 25;124(6):731-40. Epub 2011 Jul 25.

University of Massachusetts Medical School, Department of Medicine/Division of Cardiovascular Medicine, Worcester, MA 01605, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.111.030775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589548PMC
August 2011

Epigenetic control of angiogenesis via DNA methylation.

Circulation 2011 Jun 13;123(25):2916-8. Epub 2011 Jun 13.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.111.033092DOI Listing
June 2011

Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction.

Clin Exp Pharmacol Physiol 2011 May;38(5):328-33

Cardiovascular Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1681.2011.05509.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086994PMC
May 2011

Inflammation, kidney function and albuminuria in the Framingham Offspring cohort.

Nephrol Dial Transplant 2011 Mar 3;26(3):920-6. Epub 2010 Aug 3.

Division of Nephrology, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ndt/gfq471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108344PMC
March 2011

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

Authors:
Abbas Dehghan Josée Dupuis Maja Barbalic Joshua C Bis Gudny Eiriksdottir Chen Lu Niina Pellikka Henri Wallaschofski Johannes Kettunen Peter Henneman Jens Baumert David P Strachan Christian Fuchsberger Veronique Vitart James F Wilson Guillaume Paré Silvia Naitza Megan E Rudock Ida Surakka Eco J C de Geus Behrooz Z Alizadeh Jack Guralnik Alan Shuldiner Toshiko Tanaka Robert Y L Zee Renate B Schnabel Vijay Nambi Maryam Kavousi Samuli Ripatti Matthias Nauck Nicholas L Smith Albert V Smith Jouko Sundvall Paul Scheet Yongmei Liu Aimo Ruokonen Lynda M Rose Martin G Larson Ron C Hoogeveen Nelson B Freimer Alexander Teumer Russell P Tracy Lenore J Launer Julie E Buring Jennifer F Yamamoto Aaron R Folsom Eric J G Sijbrands James Pankow Paul Elliott John F Keaney Wei Sun Antti-Pekka Sarin João D Fontes Sunita Badola Brad C Astor Albert Hofman Anneli Pouta Karl Werdan Karin H Greiser Oliver Kuss Henriette E Meyer zu Schwabedissen Joachim Thiery Yalda Jamshidi Ilja M Nolte Nicole Soranzo Timothy D Spector Henry Völzke Alexander N Parker Thor Aspelund David Bates Lauren Young Kim Tsui David S Siscovick Xiuqing Guo Jerome I Rotter Manuela Uda David Schlessinger Igor Rudan Andrew A Hicks Brenda W Penninx Barbara Thorand Christian Gieger Joe Coresh Gonneke Willemsen Tamara B Harris Andre G Uitterlinden Marjo-Riitta Järvelin Kenneth Rice Dörte Radke Veikko Salomaa Ko Willems van Dijk Eric Boerwinkle Ramachandran S Vasan Luigi Ferrucci Quince D Gibson Stefania Bandinelli Harold Snieder Dorret I Boomsma Xiangjun Xiao Harry Campbell Caroline Hayward Peter P Pramstaller Cornelia M van Duijn Leena Peltonen Bruce M Psaty Vilmundur Gudnason Paul M Ridker Georg Homuth Wolfgang Koenig Christie M Ballantyne Jacqueline C M Witteman Emelia J Benjamin Markus Perola Daniel I Chasman

Circulation 2011 Feb 7;123(7):731-8. Epub 2011 Feb 7.

Erasmus Medical Center, Dr Molewaterplein 50, Rotterdam, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.110.948570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147232PMC
February 2011

Effects of Concord grape juice on ambulatory blood pressure in prehypertension and stage 1 hypertension.

Am J Clin Nutr 2010 Nov 15;92(5):1052-9. Epub 2010 Sep 15.

Evans Department of Medicine and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA 02118, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3945/ajcn.2010.29905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954442PMC
November 2010

Exhaled carbon monoxide and risk of metabolic syndrome and cardiovascular disease in the community.

Circulation 2010 Oct 27;122(15):1470-7. Epub 2010 Sep 27.

The Framingham Heart Study, 73 Mount Wayte Ave, Ste 2, Framingham, MA 01702-5803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.110.941013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975571PMC
October 2010

AMP-activated protein kinase: a stress-responsive kinase with implications for cardiovascular disease.

Curr Opin Pharmacol 2010 Apr 8;10(2):111-5. Epub 2010 Jan 8.

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue N, S3-855, Worcester, MA 01655, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coph.2009.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843779PMC
April 2010

Predicting ischemic heart disease in women: the value of endothelial function.

J Am Coll Cardiol 2010 Apr;55(16):1697-9

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2009.10.074DOI Listing
April 2010

Kynurenine is an endothelium-derived relaxing factor produced during inflammation.

Nat Med 2010 Mar 28;16(3):279-85. Epub 2010 Feb 28.

Centre for Vascular Research, School of Medical Sciences (Pathology) and Bosch Institute, Faculty of Medicine, University of Sydney, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.2092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556275PMC
March 2010

Downstream targets and intracellular compartmentalization in Nox signaling.

Antioxid Redox Signal 2009 Oct;11(10):2467-80

Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School Worcester, Massachusetts 01605, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ars.2009.2594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861540PMC
October 2009

Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study.

Atherosclerosis 2009 Apr 9;203(2):509-14. Epub 2008 Jul 9.

National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702-5827, United States.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690511PMC
http://dx.doi.org/10.1016/j.atherosclerosis.2008.06.031DOI Listing
April 2009

Vascular rhythms and adaptation: do your arteries know what time it is?

Circulation 2009 Mar 9;119(11):1463-6. Epub 2009 Mar 9.

Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.108.847798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707835PMC
March 2009

Polyploidy and dysregulated ROS signaling: the school of hard Nox?

Cell Cycle 2009 Mar 15;8(6):797. Epub 2009 Mar 15.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.8.6.8336DOI Listing
March 2009

Relation of smoking status to a panel of inflammatory markers: the framingham offspring.

Atherosclerosis 2008 Nov 4;201(1):217-24. Epub 2008 Mar 4.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA 01702-5827, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2007.12.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783981PMC
November 2008

Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction.

Circulation 2008 Sep;118(13):1347-57

Department of Cardiology, 2nd Medical Clinic of the University Hospital Mainz, Johannes Gutenberg University, Mainz, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.108.784298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756193PMC
September 2008

Circulating ghrelin, leptin, and soluble leptin receptor concentrations and cardiometabolic risk factors in a community-based sample.

J Clin Endocrinol Metab 2008 Aug 20;93(8):3149-57. Epub 2008 May 20.

The Framingham Study, Boston University School of Medicine, Framingham, Massachusetts 01702-5803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2008-0207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515078PMC
August 2008

Regulation of ROS signal transduction by NADPH oxidase 4 localization.

J Cell Biol 2008 Jun 23;181(7):1129-39. Epub 2008 Jun 23.

Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200709049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442210PMC
June 2008

Systemic inflammation and COPD: the Framingham Heart Study.

Chest 2008 Jan 1;133(1):19-25. Epub 2007 Oct 1.

Section of Pulmonary, Allergy, and Critical Care Medicine, Boston University School of Medicine, Boston, MA 02118, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.07-0058DOI Listing
January 2008

Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers.

Arterioscler Thromb Vasc Biol 2007 Dec 11;27(12):2650-6. Epub 2007 Oct 11.

Section of Cardiology, Boston Medical Center, 88 East Newton Street, Boston, MA 02118, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.107.153288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596308PMC
December 2007

Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study.

Diabetes Care 2007 Oct 22;30(10):2529-35. Epub 2007 Jun 22.

General Medicine Division and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/dc07-0817DOI Listing
October 2007

Clinical correlates of circulating visfatin levels in a community-based sample.

Diabetes Care 2007 May 29;30(5):1278-80. Epub 2007 Jan 29.

Framingham Study, Boston University School of Medicine, Framingham, Massachusetts, Framingham, MA 01702-5803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/dc06-2353DOI Listing
May 2007

Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease.

J Am Coll Nutr 2007 Apr;26(2):95-102

Evans Department of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773609PMC
http://dx.doi.org/10.1080/07315724.2007.10719590DOI Listing
April 2007