John Deeken

John Deeken

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John Deeken

John Deeken

Publications by authors named "John Deeken"

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EPG5 Variants with Modest Functional Impact Result in an Ameliorated and Primarily Neurological Phenotype in a 3.5-Year-Old Patient with Vici Syndrome.

Neuropediatrics 2019 Aug 21;50(4):257-261. Epub 2019 Jun 21.

Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1055/s-0039-1692129DOI Listing
August 2019

Endosomal trafficking defects in patient cells with biallelic variants.

Genes Dis 2019 Mar 7;6(1):56-67. Epub 2019 Jan 7.

Inova Translational Medicine Institute, Inova Health System, Fairfax, VA, United States.

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http://dx.doi.org/10.1016/j.gendis.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411657PMC
March 2019

A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies.

Cancer Chemother Pharmacol 2018 03 1;81(3):587-596. Epub 2018 Feb 1.

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1007/s00280-018-3533-8DOI Listing
March 2018

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

N Engl J Med 2018 02;378(8):731-739

From Memorial Sloan Kettering Cancer Center (A. Drilon, J.F.H., R.B., M.L., D.M.H.) and Weill Cornell Medical College (A. Drilon, D.M.H.), New York; University of Texas Southwestern Medical Center-Children's Health, Dallas (T.W.L.); Stanford Cancer Center, Stanford University, Palo Alto (S.K.), Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California (L.M.), and UCLA David Geffen School of Medicine (N.F.), Los Angeles, and Loxo Oncology, South San Francisco (B.B.T., K.E., S.C., N.C.K., M.C.C.) - all in California; Dana-Farber-Boston Children's Cancer and Blood Disorders Center (S.G.D.), Dana-Farber Cancer Institute (G.D.D., M.N.), Ludwig Center at Harvard (G.D.D.), and Massachusetts General Hospital (A.F.F.) - all in Boston; the Finsen Center, Rigshospitalet, Copenhagen (U.N.L.); University of Colorado, Aurora (R.C.D.); St. Jude Children's Research Hospital, Memphis (A.S.P.), and Vanderbilt University, Nashville (J.B.) - both in Tennessee; Cincinnati Children's Hospital Medical Center, Cincinnati (B.T.); University Hospitals of Cleveland Medical Center (A. Dowlati) and Taussig Cancer Institute, Cleveland Clinic (D.P.S.S.), Cleveland; University of Pennsylvania Perelman School of Medicine, Department of Otorhinolaryngology and Head and Neck Surgery, and the Abramson Cancer Center (M.S.B.), and Fox Chase Cancer Center (W.S.E.-D.), Philadelphia; University of Washington-Seattle Cancer Care Alliance (C.B.), Seattle Children's Hospital (E.R.R.), and Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center (D.S. Hawkins), Seattle; University of Texas M.D. Anderson Cancer Center, Houston (F.M.-B., D.S. Hong); Inova Schar Cancer Institute, Falls Church, VA (J.D.); START Madrid, Centro Integral Oncológico Clara Campal, Madrid (V.B.); Nemours Children's Hospital, Orlando (R.N.), and Memorial Cancer Institute-Florida International University, Miami (L.E.R.) - both in Florida; Oregon Health and Science University, Portland (M.T.); and WVU Cancer Institute, West Virginia University, Morgantown (P.C.M.).

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http://dx.doi.org/10.1056/NEJMoa1714448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857389PMC
February 2018

Identification of novel SNPs associated with risk and prognosis in patients with castration-resistant prostate cancer.

Pharmacogenomics 2016 Dec 24;17(18):1979-1986. Epub 2016 Nov 24.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, 9000 Rockville Pike, Building 10, Room 5A01, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.2217/pgs-2016-0134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558514PMC
December 2016

Safety and efficacy of hypofractionated stereotactic body reirradiation in head and neck cancer: Long-term follow-up of a large series.

Head Neck 2015 Oct 25;37(10):1403-9. Epub 2014 Sep 25.

Departments of Radiation Oncology, Medical Oncology, and Head and Neck Surgery, Lombardi Comprehensive Cancer Center, Georgetown University Hospital, Washington, DC.

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http://dx.doi.org/10.1002/hed.23763DOI Listing
October 2015

Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib.

Cancer Chemother Pharmacol 2015 Oct 2;76(4):813-9. Epub 2015 Sep 2.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Bunting-Blaustein Cancer Research Bldg. Room 1M52, Baltimore, MD, 21231-1000, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs00280-015-28
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http://link.springer.com/10.1007/s00280-015-2856-y
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http://dx.doi.org/10.1007/s00280-015-2856-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577782PMC
October 2015

Irreversible multitargeted ErbB family inhibitors for therapy of lung and breast cancer.

Curr Cancer Drug Targets 2015 ;14(9):775-93

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

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September 2015

RAS Mutations Beyond KRAS Exon 2: A Review and Discussion of Clinical Trial Data.

Curr Treat Options Oncol 2015 Jul;16(7):33

INOVA Medical Group, 8505 Arlington Blvd. Suite 100, Fairfax, VA, 22031, USA,

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http://link.springer.com/10.1007/s11864-015-0350-8
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http://dx.doi.org/10.1007/s11864-015-0350-8DOI Listing
July 2015

A phase I study of oral ixabepilone in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2014 May 25;73(5):1071-8. Epub 2014 Mar 25.

Inova Comprehensive Cancer and Research Center, 3300 Gallows Road, Falls Church, VA, 22042, USA,

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http://dx.doi.org/10.1007/s00280-014-2443-7DOI Listing
May 2014

Combination antiretroviral therapy (cART) component ritonavir significantly alters docetaxel exposure.

Cancer Chemother Pharmacol 2014 Apr 2;73(4):729-36. Epub 2014 Feb 2.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Room 1M52, Baltimore, MD, 21231-1000, USA,

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http://dx.doi.org/10.1007/s00280-014-2399-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968228PMC
April 2014

Pharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine.

Pharmacogenet Genomics 2014 Feb;24(2):81-93

aInnovation Center for Biomedical Informatics bLombardi Comprehensive Cancer Center, Developmental Therapeutics Program cDepartment of Neurology, Georgetown University Medical Center dDepartment of Mathematics and Statistics, Georgetown University, Washington, District of Columbia eESAC Inc., Rockville fUS Food and Drug Administration, Silver Spring, Maryland, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888473PMC
February 2014

The rising challenge of non-AIDS-defining cancers in HIV-infected patients.

Clin Infect Dis 2012 Nov 9;55(9):1228-35. Epub 2012 Jul 9.

Division of Hematology/Oncology, Georgetown University Medical Center, 3800 Reservoir Rd NW, Washington, DC 20007, USA.

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http://dx.doi.org/10.1093/cid/cis613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529613PMC
November 2012

Reirradiation of recurrent salivary gland malignancies with fractionated stereotactic body radiation therapy.

J Radiat Oncol 2012 Jun 19;1(2):147-153. Epub 2012 Feb 19.

Department of Radiation Medicine, Georgetown University Hospital, 3800 Reservoir Rd., NW, Washington, DC 20007 USA.

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http://dx.doi.org/10.1007/s13566-012-0010-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573714PMC
June 2012

Fractionated stereotactic radiosurgery for reirradiation of head-and-neck cancer.

Int J Radiat Oncol Biol Phys 2010 Aug 7;77(5):1411-9. Epub 2010 Jan 7.

Department of Radiation Medicine, Georgetown University Hospital, Washington, DC 20007, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2009.06.070DOI Listing
August 2010

Cetuximab in the treatment of rheumatoid arthritis.

J Clin Rheumatol 2010 Jan;16(1):32-3

Department of Internal Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.

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http://dx.doi.org/10.1097/RHU.0b013e3181c8e176DOI Listing
January 2010

Targeted therapies to treat non-AIDS-defining cancers in patients with HIV on HAART therapy: treatment considerations and research outlook.

Curr Opin Oncol 2009 Sep;21(5):445-54

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.

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http://dx.doi.org/10.1097/CCO.0b013e32832f3e04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377583PMC
September 2009

The Affymetrix DMET platform and pharmacogenetics in drug development.

Authors:
John Deeken

Curr Opin Mol Ther 2009 Jun;11(3):260-8

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.

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June 2009

The 315-316 deletion determines the BXP-21 antibody epitope but has no effect on the function of wild type ABCG2 or the Q141K variant.

Mol Cell Biochem 2009 Feb 11;322(1-2):63-71. Epub 2008 Nov 11.

Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s11010-008-9940-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631614PMC
February 2009

Irinotecan and uridine diphosphate glucuronosyltransferase 1A1 pharmacogenetics: to test or not to test, that is the question.

Cancer 2008 Oct;113(7):1502-10

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia 20007, USA.

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http://doi.wiley.com/10.1002/cncr.23777
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http://dx.doi.org/10.1002/cncr.23777DOI Listing
October 2008

ABCG2: determining its relevance in clinical drug resistance.

Cancer Metastasis Rev 2007 Mar;26(1):39-57

Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s10555-007-9042-6DOI Listing
March 2007

The blood-brain barrier and cancer: transporters, treatment, and Trojan horses.

Clin Cancer Res 2007 Mar;13(6):1663-74

Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2854DOI Listing
March 2007

Immunologic therapies for gastrointestinal cancers.

Clin Colorectal Cancer 2005 May;5(1):37-49

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA.

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May 2005

Care for the caregivers: a review of self-report instruments developed to measure the burden, needs, and quality of life of informal caregivers.

J Pain Symptom Manage 2003 Oct;26(4):922-53

Department of Medicine, Georgetown University Medical Center, Washington, DC 20057, USA.

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http://dx.doi.org/10.1016/s0885-3924(03)00327-0DOI Listing
October 2003