Publications by authors named "John D Gordan"

34Publications

Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma.

Clin Liver Dis (Hoboken) 2020 Feb 26;15(2):53-58. Epub 2020 Mar 26.

UCSF Helen Diller Family Comprehensive Cancer Center University of California San Francisco San Francisco CA.

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February 2020

Nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh class B cirrhosis: Safety and clinical outcomes in a retrospective case series.

Cancer 2019 09 2;125(18):3234-3241. Epub 2019 Jun 2.

Division of Hematology and Oncology, Department of Medicine, University of California at San Francisco Medical Center, San Francisco, California.

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September 2019

Road map for fibrolamellar carcinoma: progress and goals of a diversified approach.

J Hepatocell Carcinoma 2019 31;6:41-48. Epub 2019 Jan 31.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA,

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January 2019

Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation.

Oncogene 2019 03 2;38(11):1936-1950. Epub 2018 Nov 2.

Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.

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March 2019

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer.

Nat Chem Biol 2018 08 25;14(8):768-777. Epub 2018 Jun 25.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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August 2018

Sampling strategies to capture single-cell heterogeneity.

Nat Methods 2017 Oct 4;14(10):967-970. Epub 2017 Sep 4.

Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA.

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October 2017

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib.

Mol Cancer Ther 2016 07 30;15(7):1472-84. Epub 2016 Jun 30.

The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, United Kingdom. Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom.

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July 2016

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.

PLoS Genet 2015 Jul 2;11(7):e1005305. Epub 2015 Jul 2.

Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics and Human Genetics, Diabetes Center, Institute for Regeneration Medicine and the Liver Center, University of California, San Francisco, San Francisco, California, United States of America.

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July 2015

Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.

Cell Rep 2014 Aug 7;8(4):1037-48. Epub 2014 Aug 7.

Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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August 2014

Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets.

Cancer Res 2012 Jan 17;72(1):112-21. Epub 2011 Nov 17.

Department of Medicine, Abramson Family Cancer Research Institute, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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January 2012

"And what other medications are you taking?".

J Clin Oncol 2011 Apr 18;29(11):e288-91. Epub 2011 Jan 18.

Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA.

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April 2011

HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses.

Proc Natl Acad Sci U S A 2009 Aug 12;106(34):14391-6. Epub 2009 Aug 12.

Abramson Family Cancer Research Institute, Abramson Cancer Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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August 2009

Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism.

J Biol Chem 2008 Jun 22;283(24):16309-19. Epub 2008 Apr 22.

Abramson Family Cancer Research Institute, Departments of Genetics and Medicine, University of Pennsylvania School of Medicine, and Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia Pennsylvania 19104, USA.

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June 2008

HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation.

Cancer Cell 2007 Aug;12(2):108-13

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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August 2007

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.

Genes Dev 2007 May 16;21(9):1037-49. Epub 2007 Apr 16.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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May 2007

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

Cancer Cell 2007 Apr;11(4):335-47

Abramson Family Cancer Research Institute, School of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA.

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April 2007

Hypoxia-inducible factors: central regulators of the tumor phenotype.

Curr Opin Genet Dev 2007 Feb 8;17(1):71-7. Epub 2007 Jan 8.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, PA, USA.

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February 2007

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest.

J Biol Chem 2006 Oct 7;281(40):30036-45. Epub 2006 Aug 7.

Leonard and Madlyn Abramson Family Cancer Research Institute and Howard Hughes Medical Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania 19104, USA.

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October 2006

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Genes Dev 2006 Mar;20(5):557-70

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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March 2006

ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.

J Exp Med 2004 Oct 11;200(8):1063-74. Epub 2004 Oct 11.

Molecular Immunology Section, Department of Immunology, Imperial College London, Hammersmith Campus, London W12 ONN, England, UK.

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October 2004

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.

Mol Cell Biol 2004 Oct;24(19):8477-86

The Leonard and Madlyn Abramson Family Cancer Research Institute and Cancer Center, Department of Cancer Biology, University of Pennsylvania Cancer Center, 454 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104, USA.

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October 2004