John D Gordan

John D Gordan

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John D Gordan

John D Gordan

Publications by authors named "John D Gordan"

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Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation.

Authors:
Nicole Michael Frazier Toni Brand John D Gordan Jennifer Grandis Natalia Jura

Oncogene 2019 03 2;38(11):1936-1950. Epub 2018 Nov 2.

Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.

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http://www.nature.com/articles/s41388-018-0537-0
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http://dx.doi.org/10.1038/s41388-018-0537-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417953PMC
March 2019

Translation control of the immune checkpoint in cancer and its therapeutic targeting.

Authors:
Yichen Xu Mauro Poggio Hyun Yong Jin Zhen Shi Craig M Forester Ying Wang Craig R Stumpf Lingru Xue Emily Devericks Lomon So Hao G Nguyen Alice Griselin John D Gordan Sarah E Umetsu Siegfried H Reich Stephen T Worland Saurabh Asthana Maria Barna Kevin R Webster John T Cunningham Davide Ruggero

Nat Med 2019 02 14;25(2):301-311. Epub 2019 Jan 14.

Department of Urology, University of California, San Francisco, San Francisco, CA, USA.

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http://www.nature.com/articles/s41591-018-0321-2
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http://dx.doi.org/10.1038/s41591-018-0321-2DOI Listing
February 2019

Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma.

Authors:
Xinhua Song Xianqiong Liu Haichuan Wang Jingxiao Wang Yu Qiao Antonio Cigliano Kirsten Utpatel Silvia Ribback Maria G Pilo Marina Serra John D Gordan Li Che Shanshan Zhang Antonio Cossu Alberto Porcu Rosa M Pascale Frank Dombrowski Hongbo Hu Diego F Calvisi Matthias Evert Xin Chen

Clin Cancer Res 2019 Jan 3;25(1):403-413. Epub 2018 Jul 3.

Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423983PMC
January 2019

Road map for fibrolamellar carcinoma: progress and goals of a diversified approach.

Authors:
Edward R Kastenhuber John Craig Jon Ramsey Kevin M Sullivan Julien Sage Sofia de Oliveira Kimberly J Riehle John D Scott John D Gordan Nabeel Bardeesy Ghassan K Abou-Alfa

J Hepatocell Carcinoma 2019 31;6:41-48. Epub 2019 Jan 31.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA,

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http://dx.doi.org/10.2147/JHC.S194764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362920PMC
January 2019

Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in Mutant Cholangiocarcinoma Harboring a Novel Fusion.

Authors:
Huat C Lim Meagan Montesion Thomas Botton Eric A Collisson Sarah E Umetsu Spencer C Behr John D Gordan Phil J Stephens Robin K Kelley

Oncologist 2018 Sep 5;23(9):998-1003. Epub 2018 Apr 5.

Department of Medicine, University of California, San Francisco, San Francisco, California, USA

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http://dx.doi.org/10.1634/theoncologist.2017-0645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192605PMC
September 2018

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer.

Authors:
Hayley J Donnella James T Webber Rebecca S Levin Roman Camarda Olga Momcilovic Nora Bayani Khyati N Shah James E Korkola Kevan M Shokat Andrei Goga John D Gordan Sourav Bandyopadhyay

Nat Chem Biol 2018 08 25;14(8):768-777. Epub 2018 Jun 25.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/s41589-018-0081-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051919PMC
August 2018

Sampling strategies to capture single-cell heterogeneity.

Authors:
Satwik Rajaram Louise E Heinrich John D Gordan Jayant Avva Kathy M Bonness Agnieszka K Witkiewicz James S Malter Chloe E Atreya Robert S Warren Lani F Wu Steven J Altschuler

Nat Methods 2017 Oct 4;14(10):967-970. Epub 2017 Sep 4.

Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA.

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http://www.nature.com/doifinder/10.1038/nmeth.4427
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http://dx.doi.org/10.1038/nmeth.4427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658002PMC
October 2017

An Optimized Chromatographic Strategy for Multiplexing In Parallel Reaction Monitoring Mass Spectrometry: Insights from Quantitation of Activated Kinases.

Authors:
Anatoly Urisman Rebecca S Levin John D Gordan James T Webber Hilda Hernandez Yasushi Ishihama Kevan M Shokat Alma L Burlingame

Mol Cell Proteomics 2017 02 11;16(2):265-277. Epub 2016 Dec 11.

§Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1074/mcp.M116.058172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294213PMC
February 2017

Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma.

Authors:
Supriya K Saha John D Gordan Benjamin P Kleinstiver Phuong Vu Mortada S Najem Jia-Chi Yeo Lei Shi Yasutaka Kato Rebecca S Levin James T Webber Leah J Damon Regina K Egan Patricia Greninger Ultan McDermott Mathew J Garnett Roger L Jenkins Kimberly M Rieger-Christ Travis B Sullivan Aram F Hezel Andrew S Liss Yusuke Mizukami Lipika Goyal Cristina R Ferrone Andrew X Zhu J Keith Joung Kevan M Shokat Cyril H Benes Nabeel Bardeesy

Cancer Discov 2016 07 26;6(7):727-39. Epub 2016 May 26.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-15-1442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458737PMC
July 2016

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib.

Authors:
Rowan E Miller Rachel Brough Ilirjana Bajrami Chris T Williamson Simon McDade James Campbell Asha Kigozi Rumana Rafiq Helen Pemberton Rachel Natrajan Josephine Joel Holly Astley Claire Mahoney Jonathan D Moore Chris Torrance John D Gordan James T Webber Rebecca S Levin Kevan M Shokat Sourav Bandyopadhyay Christopher J Lord Alan Ashworth

Mol Cancer Ther 2016 07 30;15(7):1472-84. Epub 2016 Jun 30.

The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, United Kingdom. Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0554DOI Listing
July 2016

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.

Authors:
Kimberley J Evason Macrina T Francisco Vladislava Juric Sanjeev Balakrishnan Maria Del Pilar Lopez Pazmino John D Gordan Sanjay Kakar Jan Spitsbergen Andrei Goga Didier Y R Stainier

PLoS Genet 2015 Jul 2;11(7):e1005305. Epub 2015 Jul 2.

Department of Biochemistry and Biophysics, Programs in Developmental and Stem Cell Biology, Genetics and Human Genetics, Diabetes Center, Institute for Regeneration Medicine and the Liver Center, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489858PMC
July 2015

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Authors:
Maria M Martins Alicia Y Zhou Alexandra Corella Dai Horiuchi Christina Yau Taha Rakshandehroo John D Gordan Rebecca S Levin Jeff Johnson John Jascur Mike Shales Antonio Sorrentino Jaime Cheah Paul A Clemons Alykhan F Shamji Stuart L Schreiber Nevan J Krogan Kevan M Shokat Frank McCormick Andrei Goga Sourav Bandyopadhyay

Cancer Discov 2015 Feb 12;5(2):154-67. Epub 2014 Dec 12.

University of California, San Francisco, San Francisco, California.

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http://cancerdiscovery.aacrjournals.org/content/5/2/154.full
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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-14-0552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407699PMC
February 2015

Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.

Authors:
Martin L Sos Rebecca S Levin John D Gordan Juan A Oses-Prieto James T Webber Megan Salt Byron Hann Alma L Burlingame Frank McCormick Sourav Bandyopadhyay Kevan M Shokat

Cell Rep 2014 Aug 7;8(4):1037-48. Epub 2014 Aug 7.

Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294625PMC
August 2014

Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets.

Authors:
Vijay R Dondeti Bradley Wubbenhorst Priti Lal John D Gordan Kurt D'Andrea Edward F Attiyeh M Celeste Simon Katherine L Nathanson

Cancer Res 2012 Jan 17;72(1):112-21. Epub 2011 Nov 17.

Department of Medicine, Abramson Family Cancer Research Institute, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251639PMC
January 2012

"And what other medications are you taking?".

Authors:
John D Gordan Wen-Yee Chay R Kate Kelley Andrew H Ko Su-Pin Choo Alan P Venook

J Clin Oncol 2011 Apr 18;29(11):e288-91. Epub 2011 Jan 18.

Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1200/JCO.2010.32.8054DOI Listing
April 2011

HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses.

Authors:
Jessica A Bertout Amar J Majmundar John D Gordan Jennifer C Lam Dara Ditsworth Brian Keith Eric J Brown Katherine L Nathanson M Celeste Simon

Proc Natl Acad Sci U S A 2009 Aug 12;106(34):14391-6. Epub 2009 Aug 12.

Abramson Family Cancer Research Institute, Abramson Cancer Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0907357106
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http://dx.doi.org/10.1073/pnas.0907357106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726037PMC
August 2009

HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma.

Authors:
John D Gordan Priti Lal Vijay R Dondeti Richard Letrero Krishna N Parekh C Elisa Oquendo Roger A Greenberg Keith T Flaherty W Kimryn Rathmell Brian Keith M Celeste Simon Katherine L Nathanson

Cancer Cell 2008 Dec;14(6):435-46

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ccr.2008.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621440PMC
December 2008

Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism.

Authors:
Regina M Young Shang-Jui Wang John D Gordan Xinjun Ji Stephen A Liebhaber M Celeste Simon

J Biol Chem 2008 Jun 22;283(24):16309-19. Epub 2008 Apr 22.

Abramson Family Cancer Research Institute, Departments of Genetics and Medicine, University of Pennsylvania School of Medicine, and Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia Pennsylvania 19104, USA.

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http://dx.doi.org/10.1074/jbc.M710079200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423241PMC
June 2008

HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation.

Authors:
John D Gordan Craig B Thompson M Celeste Simon

Cancer Cell 2007 Aug;12(2):108-13

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ccr.2007.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215289PMC
August 2007

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.

Authors:
Julian J Lum Thi Bui Michaela Gruber John D Gordan Ralph J DeBerardinis Kelly L Covello M Celeste Simon Craig B Thompson

Genes Dev 2007 May 16;21(9):1037-49. Epub 2007 Apr 16.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gad.1529107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855230PMC
May 2007

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

Authors:
John D Gordan Jessica A Bertout Cheng-Jun Hu J Alan Diehl M Celeste Simon

Cancer Cell 2007 Apr;11(4):335-47

Abramson Family Cancer Research Institute, School of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ccr.2007.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145406PMC
April 2007

Hypoxia-inducible factors: central regulators of the tumor phenotype.

Authors:
John D Gordan M Celeste Simon

Curr Opin Genet Dev 2007 Feb 8;17(1):71-7. Epub 2007 Jan 8.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, PA, USA.

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http://dx.doi.org/10.1016/j.gde.2006.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215290PMC
February 2007

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest.

Authors:
Fang Zhang Robert B Hamanaka Ekaterina Bobrovnikova-Marjon John D Gordan Mu-Shui Dai Hua Lu M Celeste Simon J Alan Diehl

J Biol Chem 2006 Oct 7;281(40):30036-45. Epub 2006 Aug 7.

Leonard and Madlyn Abramson Family Cancer Research Institute and Howard Hughes Medical Institute, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1074/jbc.M604674200DOI Listing
October 2006

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Authors:
Kelly L Covello James Kehler Hongwei Yu John D Gordan Andrew M Arsham Cheng-Jun Hu Patricia A Labosky M Celeste Simon Brian Keith

Genes Dev 2006 Mar;20(5):557-70

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gad.1399906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410808PMC
March 2006

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.

Authors:
Sara B Cullinan John D Gordan Jianping Jin J Wade Harper J Alan Diehl

Mol Cell Biol 2004 Oct;24(19):8477-86

The Leonard and Madlyn Abramson Family Cancer Research Institute and Cancer Center, Department of Cancer Biology, University of Pennsylvania Cancer Center, 454 BRB II/III, 421 Curie Blvd., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1128/MCB.24.19.8477-8486.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516753PMC
October 2004

ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.

Authors:
Hongyan Wang Fiona E McCann John D Gordan Xiang Wu Monika Raab Talat H Malik Daniel M Davis Christopher E Rudd

J Exp Med 2004 Oct 11;200(8):1063-74. Epub 2004 Oct 11.

Molecular Immunology Section, Department of Immunology, Imperial College London, Hammersmith Campus, London W12 ONN, England, UK.

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http://dx.doi.org/10.1084/jem.20040780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211848PMC
October 2004