John D Carpten

John D Carpten

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John D Carpten

John D Carpten

Publications by authors named "John D Carpten"

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Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.

Sci Rep 2019 Feb 6;9(1):1482. Epub 2019 Feb 6.

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, United States.

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http://www.nature.com/articles/s41598-018-37574-8
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http://dx.doi.org/10.1038/s41598-018-37574-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365517PMC
February 2019

Profiling targetable immune checkpoints in osteosarcoma.

Oncoimmunology 2018 11;7(12):e1475873. Epub 2018 Sep 11.

Department of Translational Genomics.

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http://dx.doi.org/10.1080/2162402X.2018.1475873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279416PMC
September 2018

Translating RNA sequencing into clinical diagnostics: opportunities and challenges.

Nat Rev Genet 2016 May 21;17(5):257-71. Epub 2016 Mar 21.

Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

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http://dx.doi.org/10.1038/nrg.2016.10DOI Listing
May 2016

Successful Treatment of Genetically Profiled Pediatric Extranodal NK/T-Cell Lymphoma Targeting Oncogenic STAT3 Mutation.

Pediatr Blood Cancer 2016 Apr 5;63(4):727-30. Epub 2016 Jan 5.

Hyundai Cancer Genomics Center, Children's Hospital of Orange County, Orange, California.

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http://dx.doi.org/10.1002/pbc.25854DOI Listing
April 2016

Toward precision medicine in glioblastoma: the promise and the challenges.

Neuro Oncol 2015 Aug 1;17(8):1051-63. Epub 2015 May 1.

University of California San Francisco, San Francisco, California (M.D.P, J.J.P., A.M.M., S.M.C.); Translational Genomics Research Institute, Phoenix, Arizona (S.A.B., N.L.T., W.D.T., J.A.K., M.E.B., D.W.C., J.D.C., J.M.T.); Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (K.L.L., P.Y.W.); University of Texas Health Science Center, San Antonio, Texas (J.G.K.); Memorial Sloan-Kettering Cancer Center, New York, New York (I.K.M.); The University of Texas M.D. Anderson Cancer Center, Houston, Texas (J.F.d.G.); University of Utah Huntsman Cancer Institute, Salt Lake City, Utah (H.C.); University of California Los Angeles, Los Angeles, California (T.F.C.); Iowa Spine and Brain Institute, Waterloo, Iowa (T.C.R.).

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http://dx.doi.org/10.1093/neuonc/nov031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490873PMC
August 2015

8q24 risk alleles and prostate cancer in African-Barbadian men.

Prostate 2014 Dec 22;74(16):1579-88. Epub 2014 Sep 22.

Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.22871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322001PMC
December 2014

Open-access synthetic spike-in mRNA-seq data for cancer gene fusions.

BMC Genomics 2014 Sep 30;15:824. Epub 2014 Sep 30.

Translational Genomics Research Institute (TGen), 445 N 5th Street, SUITE 600, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1186/1471-2164-15-824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190330PMC
September 2014

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

PLoS One 2013 30;8(10):e76438. Epub 2013 Oct 30.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare (VGPCC), Scottsdale, Arizona, United States of America ; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076438PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813699PMC
August 2014

Whole-genome sequencing of an aggressive BRAF wild-type papillary thyroid cancer identified EML4-ALK translocation as a therapeutic target.

World J Surg 2014 Jun;38(6):1296-305

Translational Genomics Research Institute, 445 N. Fifth St, Phoenix, AZ, 85004, USA,

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http://dx.doi.org/10.1007/s00268-014-2485-3DOI Listing
June 2014

Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing.

Int J Gynecol Cancer 2014 Feb;24(2):329-38

*Translational Genomics Research Institute; †Comprehensive Cancer Care, St Joseph's Hospital and Medical Center, Phoenix; ‡Mayo Clinic, Scottsdale; §Department of Obstetrics and Gynecology, St Joseph's Hospital and Medical Center, and ∥Division of Gynecologic Oncology, Creighton University School of Medicine, St Joseph's Hospital and Medical Center, University of Arizona Cancer Center, Phoenix, AZ.

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http://dx.doi.org/10.1097/IGC.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921261PMC
February 2014

Long insert whole genome sequencing for copy number variant and translocation detection.

Nucleic Acids Res 2014 Jan 25;42(2):e8. Epub 2013 Sep 25.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA, Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA and Cancer Treatment Centers of America, Medical Oncology, Goodyear, AZ, 85338, USA.

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http://dx.doi.org/10.1093/nar/gkt865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902897PMC
January 2014

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs.

BMC Genomics 2013 May 4;14:302. Epub 2013 May 4.

Translational Genomics Research Institute, Neurogenomics Division, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1186/1471-2164-14-302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751438PMC
May 2013

Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma.

Cancer Metab 2013 May 29;1(1):14. Epub 2013 May 29.

Robert H, Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, 303 E, Superior Street, Lurie Building 3-250, Chicago, IL 606011, USA.

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http://cancerandmetabolism.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/2049-3002-1-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178207PMC
May 2013

EphB2 SNPs and sporadic prostate cancer risk in African American men.

PLoS One 2011 16;6(5):e19494. Epub 2011 May 16.

Division of Integrated Cancer Genomics, Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019494PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095601PMC
October 2011

Contribution of HPC1 (RNASEL) and HPCX variants to prostate cancer in a founder population.

Prostate 2010 Nov;70(15):1716-27

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1002/pros.21207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404133PMC
November 2010

Family-based samples can play an important role in genetic association studies.

Cancer Epidemiol Biomarkers Prev 2008 Sep;17(9):2208-14

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665689PMC
September 2008

Chromosome 8q24 risk variants in hereditary and non-hereditary prostate cancer patients.

Prostate 2008 Apr;68(5):489-97

Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1002/pros.20695DOI Listing
April 2008

PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation.

Br J Haematol 2008 Feb 5;140(3):344-7. Epub 2007 Dec 5.

Pharmaceutical Genomics Division, The Translational Genomics Research Institute (TGen), Phoenix/Scottsdale, AZ, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06920.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385948PMC
February 2008

The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth.

J Clin Invest 2005 Mar;115(3):622-31

Department of Genetics, Center for Human Genetics, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1172/JCI22263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548698PMC
March 2005

Evidence for a general cancer susceptibility locus at 3p24 in families with hereditary prostate cancer.

Cancer Lett 2005 Mar;219(2):177-82

Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.canlet.2004.10.005DOI Listing
March 2005

Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer.

Genes Chromosomes Cancer 2004 Feb;39(2):119-25

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/gcc.10308DOI Listing
February 2004

Familial isolated hyperparathyroidism is rarely caused by germline mutation in HRPT2, the gene for the hyperparathyroidism-jaw tumor syndrome.

J Clin Endocrinol Metab 2004 Jan;89(1):96-102

Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2003-030675DOI Listing
January 2004

Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.

Cancer Res 2003 Oct;63(20):6795-801

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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October 2003

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases.

Nat Genet 2002 Dec 4;32(4):581-3. Epub 2002 Nov 4.

Department of Cancer Biology, ND50, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/ng1021DOI Listing
December 2002

Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility.

Cancer Res 2002 Mar;62(6):1784-9

Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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March 2002

Identification of six novel genes by experimental validation of GeneMachine predicted genes.

Gene 2002 Feb;284(1-2):203-13

Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/s0378-1119(01)00897-6DOI Listing
February 2002