John D Altman

John D Altman

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John D Altman

John D Altman

Publications by authors named "John D Altman"

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MHC-I peptide binding activity assessed by exchange after cleavage of peptide covalently linked to ╬▓2-microglobulin.

Anal Biochem 2019 Nov 13;584:113328. Epub 2019 Jun 13.

Program in Immunology and Microbiology, University of Massachusetts Medical School, Worcester, MA, 01605, United States; Department of Pathology, University of Massachusetts Medical School, Worcester, MA, 01605, United States; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2019.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760266PMC
November 2019

Empty conformers of HLA-B preferentially bind CD8 and regulate CD8 T cell function.

Elife 2018 05 9;7. Epub 2018 May 9.

Department of Microbiology and Immunology, Michigan Medicine, University of Michigan, Ann Arbor, United States.

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http://dx.doi.org/10.7554/eLife.36341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990358PMC
May 2018

Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU).

PLoS One 2018 5;13(2):e0191837. Epub 2018 Feb 5.

Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191837PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798775PMC
March 2018

MHC-Peptide Tetramers to Visualize Antigen-Specific T Cells.

Curr Protoc Immunol 2016 11 1;115:17.3.1-17.3.44. Epub 2016 Nov 1.

Stanford University School of Medicine and The Howard Hughes Medical Institute, Palo Alto, California.

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http://dx.doi.org/10.1002/cpim.14DOI Listing
November 2016

Molecular Analysis of Lipid-Reactive V╬┤1 ╬│╬┤ T Cells Identified by CD1c Tetramers.

J Immunol 2016 Feb 11;196(4):1933-42. Epub 2016 Jan 11.

Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637; Committee on Immunology, University of Chicago, Chicago, IL 60637;

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http://dx.doi.org/10.4049/jimmunol.1502202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744554PMC
February 2016

Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by ╬▒╬▓ T cells.

Proc Natl Acad Sci U S A 2014 Oct 8;111(43):E4648-57. Epub 2014 Oct 8.

Departments of Biochemistry and Molecular Biology and Committee on Immunology, University of Chicago, Chicago, IL 60637;

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http://dx.doi.org/10.1073/pnas.1408549111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217448PMC
October 2014

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens.

Nat Immunol 2014 Feb 22;15(2):177-85. Epub 2013 Dec 22.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ni.2790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932764PMC
February 2014

CD8 T cell memory recall is enhanced by novel direct interactions with CD4 T cells enabled by MHC class II transferred from APCs.

PLoS One 2013 18;8(2):e56999. Epub 2013 Feb 18.

Department of Microbiology and Immunology, Yerkes National Primate Research Center and Emory University School of Medicine, Atlanta, Georgia, United States.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056999PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575485PMC
August 2013

Platelets support a protective immune response to LCMV by preventing splenic necrosis.

Blood 2013 Feb 7;121(6):940-50. Epub 2012 May 7.

Emory Vaccine Center and Department of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-08-37
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http://dx.doi.org/10.1182/blood-2011-08-376822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567341PMC
February 2013

Use of replication restricted recombinant vesicular stomatitis virus vectors for detection of antigen-specific T cells.

J Immunol Methods 2012 Jan 8;375(1-2):118-28. Epub 2011 Oct 8.

Emory Vaccine Center at the Yerkes National Primate Center at Emory University, United States.

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http://dx.doi.org/10.1016/j.jim.2011.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253942PMC
January 2012

Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system.

Proc Natl Acad Sci U S A 2011 Nov 15;108(48):19335-40. Epub 2011 Nov 15.

Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1112969108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228429PMC
November 2011

Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis.

Nat Rev Immunol 2011 07 15;11(8):551-8. Epub 2011 Jul 15.

Department of Microbiology and Immunology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nri3020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699324PMC
July 2011

New design of MHC class II tetramers to accommodate fundamental principles of antigen presentation.

J Immunol 2009 Dec;183(12):7949-57

Department of Immunology and Microbial Sciences, Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.4049/jimmunol.0902493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795019PMC
December 2009

Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection.

Nature 2008 Aug;454(7206):894-8

Emory Vaccine Center and Department of Microbiology and Immunology, Yerkes National Primate Research Center and Emory University School of Medicine, 954 Gatewood Road, Atlanta, Georgia 30329, USA.

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http://dx.doi.org/10.1038/nature07199DOI Listing
August 2008

Actin integrity is indispensable for CD95/Fas-induced apoptosis of HIV-specific CD8+ T cells.

Apoptosis 2007 Dec;12(12):2175-86

Department of Microbiology and Immunology, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Drexel University, 2900 Queen Lane, Philadelphia, PA 19129, USA.

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http://dx.doi.org/10.1007/s10495-007-0128-yDOI Listing
December 2007

Memory CD8+ T cells require CD28 costimulation.

J Immunol 2007 Nov;179(10):6494-503

Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19129, USA.

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http://dx.doi.org/10.4049/jimmunol.179.10.6494DOI Listing
November 2007

Early establishment and antigen dependence of simian immunodeficiency virus-specific CD8+ T-cell defects.

J Virol 2007 Oct 1;81(20):10861-8. Epub 2007 Aug 1.

Department of Microbiology and Immunology, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.

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http://dx.doi.org/10.1128/JVI.00813-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045568PMC
October 2007

Increased mitochondrial mass characterizes the survival defect of HIV-specific CD8(+) T cells.

Blood 2007 Mar 9;109(6):2505-13. Epub 2006 Nov 9.

Department of Microbiology and Immunology and Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA, 19129, USA.

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http://dx.doi.org/10.1182/blood-2006-05-021626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852206PMC
March 2007

A robust method for production of MHC tetramers with small molecule fluorophores.

J Immunol Methods 2007 Jan 22;319(1-2):13-20. Epub 2006 Sep 22.

Emory University School of Medicine, Department of Microbiology and Immunology, Atlanta, Georgia 30329, USA.

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http://dx.doi.org/10.1016/j.jim.2006.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802104PMC
January 2007

Comparison of IgG reactivities to Plasmodium vivax merozoite invasion antigens in a Brazilian Amazon population.

Am J Trop Med Hyg 2005 Aug;73(2):244-55

Emory Vaccine Center & Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.

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August 2005

Flow cytometry applications of MHC tetramers.

Authors:
John D Altman

Methods Cell Biol 2004 ;75:433-52

Emory University, School of Medicine, Department of Microbiology and Immunology, The Emory Vaccine Center, Atlanta, Georgia 30329, USA.

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http://dx.doi.org/10.1016/s0091-679x(04)75017-7DOI Listing
March 2005

Complement C5a receptor is essential for the optimal generation of antiviral CD8+ T cell responses.

J Immunol 2004 Aug;173(4):2524-9

Department of Microbiology and Immunology and Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19129, USA.

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http://www.jimmunol.org/content/173/4/2524.full.pdf
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http://dx.doi.org/10.4049/jimmunol.173.4.2524DOI Listing
August 2004

HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL.

J Immunol 2004 Apr;172(7):4444-53

Departments of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19129, USA.

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http://dx.doi.org/10.4049/jimmunol.172.7.4444DOI Listing
April 2004

HIV escape: there and back again.

Nat Med 2004 Mar;10(3):229-30

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http://dx.doi.org/10.1038/nm0304-229DOI Listing
March 2004

A transgenic mouse model genetically tags all activated CD8 T cells.

J Immunol 2003 Sep;171(5):2393-401

Department of Microbiology and Immunology, Emory Vaccine Center, Emory University, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.4049/jimmunol.171.5.2393DOI Listing
September 2003

Caveats in the design of MHC class I tetramer/antigen-specific T lymphocytes dissociation assays.

J Immunol Methods 2003 Sep;280(1-2):25-35

Department of Microbiology and Immunology, Emory Vaccine Center at Yerkes, 954 Gatewood Road, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.1016/s0022-1759(03)00079-6DOI Listing
September 2003

Analysis of HLA-E peptide-binding specificity and contact residues in bound peptide required for recognition by CD94/NKG2.

J Immunol 2003 Aug;171(3):1369-75

Emory Vaccine Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.4049/jimmunol.171.3.1369DOI Listing
August 2003

MHC-peptide tetramers to visualize antigen-specific T cells.

Curr Protoc Immunol 2003 May;Chapter 17:Unit 17.3

Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1002/0471142735.im1703s53DOI Listing
May 2003

Immediate early effector functions of virus-specific CD8+CCR7+ memory cells in humans defined by HLA and CC chemokine ligand 19 tetramers.

J Immunol 2003 Mar;170(5):2461-8

Department of Microbiology and Immunology, and Emory Vaccine Research Center at Yerkes, Emory University, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.4049/jimmunol.170.5.2461DOI Listing
March 2003

IL-15 enhances survival and function of HIV-specific CD8+ T cells.

Blood 2003 Feb 19;101(3):1024-9. Epub 2002 Sep 19.

Department of Microbiology and Immunology, Drexel University College of Medicine, Drexel University, Philadelphia, PA 19129, USA.

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http://dx.doi.org/10.1182/blood-2002-07-1957DOI Listing
February 2003

Major histocompatibility complex (MHC) tetramer technology: an evaluation.

Biol Res Nurs 2002 Oct;4(2):115-27

Nell Hodgson Woodruff School of Nursing at Emory University, Atlanta, GA 30322-4207, USA.

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http://journals.sagepub.com/doi/ 10.1177/1099800402238332
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http://dx.doi.org/10.1177/1099800402238332DOI Listing
October 2002

CD94/NKG2 expression does not inhibit cytotoxic function of lymphocytic choriomeningitis virus-specific CD8+ T cells.

J Immunol 2002 Jul;169(2):693-701

Emory Vaccine Research Center and Department of Microbiology and Immunology, Emory University, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.4049/jimmunol.169.2.693DOI Listing
July 2002

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses.

Nat Immunol 2002 Jun 20;3(6):536-41. Epub 2002 May 20.

Department of Microbiology and Immunology, MCP Hahnemann University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/ni798DOI Listing
June 2002

Role of lymphotoxin alpha in T-cell responses during an acute viral infection.

J Virol 2002 Apr;76(8):3943-51

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136110PMC
http://dx.doi.org/10.1128/jvi.76.8.3943-3951.2002DOI Listing
April 2002

Analysis of Mitochondrial Function in Antigen Specific na ve, Effector and MEmory CD8 + T Cells.

ScientificWorldJournal 2001 2;1:53. Epub 2001 Nov 2.

Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30022, USA.

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http://www.hindawi.com/journals/tswj/2001/361059/abs/
Publisher Site
http://dx.doi.org/10.1100/tsw.2001.188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083953PMC
November 2001