Publications by authors named "John Crutchley"

13Publications

Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking.

Mol Biol Cell 2020 07 13;31(14):1498-1511. Epub 2020 May 13.

Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

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http://dx.doi.org/10.1091/mbc.E20-03-0210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359570PMC
July 2020

An amphipathic helix enables septins to sense micrometer-scale membrane curvature.

J Cell Biol 2019 04 18;218(4):1128-1137. Epub 2019 Jan 18.

Department of Biology, University of North Carolina at Chapel Hill, NC

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http://dx.doi.org/10.1083/jcb.201807211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446858PMC
April 2019

Identification of a DNA Damage-Induced Alternative Splicing Pathway That Regulates p53 and Cellular Senescence Markers.

Cancer Discov 2017 07 13;7(7):766-781. Epub 2017 Mar 13.

Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501752PMC
July 2017

CLIC4 is a tumor suppressor for cutaneous squamous cell cancer.

Carcinogenesis 2012 May 1;33(5):986-95. Epub 2012 Mar 1.

Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/carcin/bgs115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334517PMC
May 2012

Molecular dissection of the checkpoint kinase Hsl1p.

Mol Biol Cell 2009 Apr 11;20(7):1926-36. Epub 2009 Feb 11.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1091/mbc.e08-08-0848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663927PMC
April 2009

The checkpoint kinase Hsl1p is activated by Elm1p-dependent phosphorylation.

Mol Biol Cell 2008 Nov 3;19(11):4675-86. Epub 2008 Sep 3.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://www.molbiolcell.org/content/early/2008/09/03/mbc.E08-
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http://www.molbiolcell.org/cgi/doi/10.1091/mbc.E08-06-0663
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http://dx.doi.org/10.1091/mbc.e08-06-0663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575171PMC
November 2008

CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiation.

J Cell Sci 2007 Aug 17;120(Pt 15):2631-40. Epub 2007 Jul 17.

Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1242/jcs.002741DOI Listing
August 2007

Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers.

Clin Cancer Res 2007 Jan;13(1):121-31

Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1562DOI Listing
January 2007

The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis.

J Biol Chem 2004 Feb 10;279(6):4632-41. Epub 2003 Nov 10.

Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, NCI, National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M311632200DOI Listing
February 2004

Genomic structure and promoter analysis of PKC-delta.

Genomics 2003 Jul;82(1):57-67

Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/s0888-7543(03)00072-7DOI Listing
July 2003