John Carpten

John Carpten

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John Carpten

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Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.

Sci Rep 2019 Feb 6;9(1):1482. Epub 2019 Feb 6.

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, United States.

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http://www.nature.com/articles/s41598-018-37574-8
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http://dx.doi.org/10.1038/s41598-018-37574-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365517PMC
February 2019

Mitochondrial biology and prostate cancer ethnic disparity.

Carcinogenesis 2018 12;39(11):1311-1319

Department of Medicinal Chemistry, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL, USA.

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https://academic.oup.com/carcin/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/carcin/bgy133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292412PMC
December 2018

Profiling targetable immune checkpoints in osteosarcoma.

Oncoimmunology 2018 11;7(12):e1475873. Epub 2018 Sep 11.

Department of Translational Genomics.

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http://dx.doi.org/10.1080/2162402X.2018.1475873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279416PMC
September 2018

Integrating the Genetics of Race and Ethnicity Into Cancer Research: Trailing Jane and John Q. Public.

JAMA Surg 2018 Apr;153(4):299-300

Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles.

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http://dx.doi.org/10.1001/jamasurg.2017.5080DOI Listing
April 2018

The era of precision oncogenomics.

Cold Spring Harb Mol Case Stud 2018 04 2;4(2). Epub 2018 Apr 2.

Institute for Genomic Medicine at Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University, Columbus, Ohio 43215, USA.

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http://dx.doi.org/10.1101/mcs.a002915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880272PMC
April 2018

Robotic salvage retroperitoneal and pelvic lymph node dissection for 'node-only' recurrent prostate cancer: technique and initial series.

BJU Int 2017 09 14;120(3):401-408. Epub 2017 Jan 14.

University of Southern California (USC) Institute of Urology, Catherine & Joseph Aresty Department of Urology, Keck School of Medicine, USC, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/bju.13741DOI Listing
September 2017

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

J Natl Cancer Inst 2017 08;109(8)

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1093/jnci/djx084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448553PMC
August 2017

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

Authors:
Maggie C Y Ng Mariaelisa Graff Yingchang Lu Anne E Justice Poorva Mudgal Ching-Ti Liu Kristin Young Lisa R Yanek Mary F Feitosa Mary K Wojczynski Kristin Rand Jennifer A Brody Brian E Cade Latchezar Dimitrov Qing Duan Xiuqing Guo Leslie A Lange Michael A Nalls Hayrettin Okut Salman M Tajuddin Bamidele O Tayo Sailaja Vedantam Jonathan P Bradfield Guanjie Chen Wei-Min Chen Alessandra Chesi Marguerite R Irvin Badri Padhukasahasram Jennifer A Smith Wei Zheng Matthew A Allison Christine B Ambrosone Elisa V Bandera Traci M Bartz Sonja I Berndt Leslie Bernstein William J Blot Erwin P Bottinger John Carpten Stephen J Chanock Yii-Der Ida Chen David V Conti Richard S Cooper Myriam Fornage Barry I Freedman Melissa Garcia Phyllis J Goodman Yu-Han H Hsu Jennifer Hu Chad D Huff Sue A Ingles Esther M John Rick Kittles Eric Klein Jin Li Barbara McKnight Uma Nayak Barbara Nemesure Adesola Ogunniyi Andrew Olshan Michael F Press Rebecca Rohde Benjamin A Rybicki Babatunde Salako Maureen Sanderson Yaming Shao David S Siscovick Janet L Stanford Victoria L Stevens Alex Stram Sara S Strom Dhananjay Vaidya John S Witte Jie Yao Xiaofeng Zhu Regina G Ziegler Alan B Zonderman Adebowale Adeyemo Stefan Ambs Mary Cushman Jessica D Faul Hakon Hakonarson Albert M Levin Katherine L Nathanson Erin B Ware David R Weir Wei Zhao Degui Zhi Donna K Arnett Struan F A Grant Sharon L R Kardia Olufunmilayo I Oloapde D C Rao Charles N Rotimi Michele M Sale L Keoki Williams Babette S Zemel Diane M Becker Ingrid B Borecki Michele K Evans Tamara B Harris Joel N Hirschhorn Yun Li Sanjay R Patel Bruce M Psaty Jerome I Rotter James G Wilson Donald W Bowden L Adrienne Cupples Christopher A Haiman Ruth J F Loos Kari E North

PLoS Genet 2017 Apr 21;13(4):e1006719. Epub 2017 Apr 21.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419579PMC
April 2017

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.

Authors:
Kristin A Rand Chi Song Eric Dean Daniel J Serie Karen Curtin Xin Sheng Donglei Hu Carol Ann Huff Leon Bernal-Mizrachi Michael H Tomasson Sikander Ailawadhi Seema Singhal Karen Pawlish Edward S Peters Cathryn H Bock Alex Stram David J Van Den Berg Christopher K Edlund David V Conti Todd Zimmerman Amie E Hwang Scott Huntsman John Graff Ajay Nooka Yinfei Kong Silvana L Pregja Sonja I Berndt William J Blot John Carpten Graham Casey Lisa Chu W Ryan Diver Victoria L Stevens Michael R Lieber Phyllis J Goodman Anselm J M Hennis Ann W Hsing Jayesh Mehta Rick A Kittles Suzanne Kolb Eric A Klein Cristina Leske Adam B Murphy Barbara Nemesure Christine Neslund-Dudas Sara S Strom Ravi Vij Benjamin A Rybicki Janet L Stanford Lisa B Signorello John S Witte Christine B Ambrosone Parveen Bhatti Esther M John Leslie Bernstein Wei Zheng Andrew F Olshan Jennifer J Hu Regina G Ziegler Sarah J Nyante Elisa V Bandera Brenda M Birmann Sue A Ingles Michael F Press Djordje Atanackovic Martha J Glenn Lisa A Cannon-Albright Brandt Jones Guido Tricot Thomas G Martin Shaji K Kumar Jeffrey L Wolf Sandra L Deming Halverson Nathaniel Rothman Angela R Brooks-Wilson S Vincent Rajkumar Laurence N Kolonel Stephen J Chanock Susan L Slager Richard K Severson Nalini Janakiraman Howard R Terebelo Elizabeth E Brown Anneclaire J De Roos Ann F Mohrbacher Graham A Colditz Graham G Giles John J Spinelli Brian C Chiu Nikhil C Munshi Kenneth C Anderson Joan Levy Jeffrey A Zonder Robert Z Orlowski Sagar Lonial Nicola J Camp Celine M Vachon Elad Ziv Daniel O Stram Dennis J Hazelett Christopher A Haiman Wendy Cozen

Cancer Epidemiol Biomarkers Prev 2016 12 1;25(12):1609-1618. Epub 2016 Sep 1.

Keck School of Medicine of USC and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-1193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524541PMC
December 2016

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.

J Natl Cancer Inst 2016 Jul 27;108(7). Epub 2016 Jan 27.

Affiliations of authors: Department of Preventive Medicine (YH, KAR, DJH, SAI, FRS, GC, LCP, XS, GAC, DOS, DVC, BEH, CAH) and Department of Urology (GAC), Keck School of Medicine, and Norris Comprehensive Cancer Center (SAI, FRS, GC, GAC, DOS, DVC, BEH, CAH), University of Southern California , Los Angeles, CA ; University of Arizona College of Medicine and University of Arizona Cancer Center , Tucson, AZ (RAK); Department of Epidemiology (SSS) and Department of Urology (CAP), University of Texas M. D. Anderson Cancer Center , Houston, TX ; Department of Public Health Sciences (BAR) and Department of Public Health Sciences (CND), Henry Ford Hospital , Detroit, MI ; Department of Preventive Medicine, Stony Brook University , Stony Brook, NY (BN, MCL, SYW, AJMH); James Buchanan Brady Urological Institute, Johns Hopkins Hospital and Medical Institution , Baltimore, MD (WBI); Division of Public Health Sciences (JLS, SK) and SWOG Statistical Center (PJG), Fred Hutchinson Cancer Research Center , Seattle, WA ; Department of Epidemiology, School of Public Health, University of Washington , Seattle, WA (JLS); Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine , Nashville, TN (WZ, WJB); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , Bethesda, MD (SIB, ZW, MBC, SJC); Cancer Genomics Research Laboratory, NCI-DCEG, SAIC-Frederick Inc. , Frederick, MD (ZW); Program for Personalized Cancer Care and Department of Surgery, NorthShore University HealthSystem , Evanston, IL (JX); Department of Genetics (NR, DR, AT, AA, DQ, SM) and Howard Hughes Medical Institute (DR, SM), Harvard Medical School, Harvard University , Boston, MA ; Broad Institute of MIT and Harvard , Cambridge, MA (NR, DR, AT, AA, DQ, SM); Department of Pathology and Laboratory Medicine and Department of Human Genetics, David Geffen School of Medicine, University of California , Los Angeles, Los Angeles, CA (BP); Howard Hughes Medical Institute, Department of Medicine, School of Medicine, University of California , San Diego, San Diego, CA (DN, MGR, RSJ); Epidemiology Research Program, American Cancer Society , Atlanta, GA (SMG, VLS); Korle Bu Teaching Hospital , Accra , Ghana (EDY, YT, RBB, AAA, ET); University of Ghana Medical School , Accra , Ghana (EDY, YT, RBB, AAA, ET); Westat , Rockville, MD (AT, SN); School of Public Health, University of California , Berkeley, Berkeley, CA (APC); Cancer Prevention Institute of California , Fremont, CA (EMJ, AWH, LC); Stanford University School of Medicine and Stanford Cancer Institute , Palo Alto, CA (EMJ, AWH, LC); Department of Urology, Northwestern University , Chicago, IL (ABM); Department of Epidemiology, Harvard School of Public Health , Boston, MA (LBS, WJB); The Translational Genomics Research Institute , Phoenix, AZ (JC); Chronic Disease Research Centre and Faculty of Medical Sciences, University of the West Indies , Bridgetown, Barbados (AJMH); Glickman Urological & Kidney Institute, Cleveland Clinic , Cleveland, OH (EAK); Center for Cancer Genomics, Wake Forest School of Medicine , Winston-Salem, NC (SLZ); Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California , San Francisco, San Francisco, CA (JSW); School of Public Health, Makerere University College of Health Sciences , Kampala, Uganda (AL, SW); Uro Care , Kampala , Uganda (SW).

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http://dx.doi.org/10.1093/jnci/djv431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948565PMC
July 2016

Translating RNA sequencing into clinical diagnostics: opportunities and challenges.

Nat Rev Genet 2016 May 21;17(5):257-71. Epub 2016 Mar 21.

Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

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http://dx.doi.org/10.1038/nrg.2016.10DOI Listing
May 2016

Successful Treatment of Genetically Profiled Pediatric Extranodal NK/T-Cell Lymphoma Targeting Oncogenic STAT3 Mutation.

Pediatr Blood Cancer 2016 Apr 5;63(4):727-30. Epub 2016 Jan 5.

Hyundai Cancer Genomics Center, Children's Hospital of Orange County, Orange, California.

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http://dx.doi.org/10.1002/pbc.25854DOI Listing
April 2016

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.

Authors:
Alexander Gusev Huwenbo Shi Gleb Kichaev Mark Pomerantz Fugen Li Henry W Long Sue A Ingles Rick A Kittles Sara S Strom Benjamin A Rybicki Barbara Nemesure William B Isaacs Wei Zheng Curtis A Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Esther M John Adam B Murphy Lisa B Signorello John Carpten M Cristina Leske Suh-Yuh Wu Anslem J M Hennis Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein John S Witte Graham Casey Sam Kaggwa Michael B Cook Daniel O Stram William J Blot Rosalind A Eeles Douglas Easton Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Kenneth Muir Graham G Giles Melissa C Southey Liesel M Fitzgerald Henrik Gronberg Fredrik Wiklund Markus Aly Brian E Henderson Johanna Schleutker Tiina Wahlfors Teuvo L J Tammela Børge G Nordestgaard Tim J Key Ruth C Travis David E Neal Jenny L Donovan Freddie C Hamdy Paul Pharoah Nora Pashayan Kay-Tee Khaw Janet L Stanford Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Christiane Maier Walther Vogel Manuel Luedeke Kathleen Herkommer Adam S Kibel Cezary Cybulski Dominika Wokolorczyk Wojciech Kluzniak Lisa Cannon-Albright Craig Teerlink Hermann Brenner Aida K Dieffenbach Volker Arndt Jong Y Park Thomas A Sellers Hui-Yi Lin Chavdar Slavov Radka Kaneva Vanio Mitev Jyotsna Batra Amanda Spurdle Judith A Clements Manuel R Teixeira Hardev Pandha Agnieszka Michael Paula Paulo Sofia Maia Andrzej Kierzek David V Conti Demetrius Albanes Christine Berg Sonja I Berndt Daniele Campa E David Crawford W Ryan Diver Susan M Gapstur J Michael Gaziano Edward Giovannucci Robert Hoover David J Hunter Mattias Johansson Peter Kraft Loic Le Marchand Sara Lindström Carmen Navarro Kim Overvad Elio Riboli Afshan Siddiq Victoria L Stevens Dimitrios Trichopoulos Paolo Vineis Meredith Yeager Gosia Trynka Soumya Raychaudhuri Frederick R Schumacher Alkes L Price Matthew L Freedman Christopher A Haiman Bogdan Pasaniuc

Nat Commun 2016 Apr 7;7:10979. Epub 2016 Apr 7.

Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms10979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829663PMC
April 2016

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.

Hum Mol Genet 2015 Oct 10;24(19):5603-18. Epub 2015 Jul 10.

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center,

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http://dx.doi.org/10.1093/hmg/ddv269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572069PMC
October 2015

Toward precision medicine in glioblastoma: the promise and the challenges.

Neuro Oncol 2015 Aug 1;17(8):1051-63. Epub 2015 May 1.

University of California San Francisco, San Francisco, California (M.D.P, J.J.P., A.M.M., S.M.C.); Translational Genomics Research Institute, Phoenix, Arizona (S.A.B., N.L.T., W.D.T., J.A.K., M.E.B., D.W.C., J.D.C., J.M.T.); Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (K.L.L., P.Y.W.); University of Texas Health Science Center, San Antonio, Texas (J.G.K.); Memorial Sloan-Kettering Cancer Center, New York, New York (I.K.M.); The University of Texas M.D. Anderson Cancer Center, Houston, Texas (J.F.d.G.); University of Utah Huntsman Cancer Institute, Salt Lake City, Utah (H.C.); University of California Los Angeles, Los Angeles, California (T.F.C.); Iowa Spine and Brain Institute, Waterloo, Iowa (T.C.R.).

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http://dx.doi.org/10.1093/neuonc/nov031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490873PMC
August 2015

8q24 risk alleles and prostate cancer in African-Barbadian men.

Prostate 2014 Dec 22;74(16):1579-88. Epub 2014 Sep 22.

Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.22871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322001PMC
December 2014

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Sonja I Berndt David V Conti Fredrick Schumacher Ying Han Sara Benlloch Dennis J Hazelett Zhaoming Wang Ed Saunders Daniel Leongamornlert Sara Lindstrom Sara Jugurnauth-Little Tokhir Dadaev Malgorzata Tymrakiewicz Daniel O Stram Kristin Rand Peggy Wan Alex Stram Xin Sheng Loreall C Pooler Karen Park Lucy Xia Jonathan Tyrer Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Merideth Yeager Laurie Burdette Charles C Chung Amy Hutchinson Kai Yu Chee Goh Mahbubl Ahmed Koveela Govindasami Michelle Guy Teuvo L J Tammela Anssi Auvinen Tiina Wahlfors Johanna Schleutker Tapio Visakorpi Katri A Leinonen Jianfeng Xu Markus Aly Jenny Donovan Ruth C Travis Tim J Key Afshan Siddiq Federico Canzian Kay-Tee Khaw Atsushi Takahashi Michiaki Kubo Paul Pharoah Nora Pashayan Maren Weischer Borge G Nordestgaard Sune F Nielsen Peter Klarskov Martin Andreas Røder Peter Iversen Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Janet L Stanford Suzanne Kolb Sarah Holt Beatrice Knudsen Antonio Hurtado Coll Susan M Gapstur W Ryan Diver Victoria L Stevens Christiane Maier Manuel Luedeke Kathleen Herkommer Antje E Rinckleb Sara S Strom Curtis Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Lisa Cannon-Albright Cezary Cybulski Dominika Wokołorczyk Wojciech Kluźniak Jong Park Thomas Sellers Hui-Yi Lin William B Isaacs Alan W Partin Hermann Brenner Aida Karina Dieffenbach Christa Stegmaier Constance Chen Edward L Giovannucci Jing Ma Meir Stampfer Kathryn L Penney Lorelei Mucci Esther M John Sue A Ingles Rick A Kittles Adam B Murphy Hardev Pandha Agnieszka Michael Andrzej M Kierzek William Blot Lisa B Signorello Wei Zheng Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Barbara Nemesure John Carpten Cristina Leske Suh-Yuh Wu Anselm Hennis Adam S Kibel Benjamin A Rybicki Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein S Lilly Zheng Jyotsna Batra Judith Clements Amanda Spurdle Manuel R Teixeira Paula Paulo Sofia Maia Chavdar Slavov Radka Kaneva Vanio Mitev John S Witte Graham Casey Elizabeth M Gillanders Daniella Seminara Elio Riboli Freddie C Hamdy Gerhard A Coetzee Qiyuan Li Matthew L Freedman David J Hunter Kenneth Muir Henrik Gronberg David E Neal Melissa Southey Graham G Giles Gianluca Severi Michael B Cook Hidewaki Nakagawa Fredrik Wiklund Peter Kraft Stephen J Chanock Brian E Henderson Douglas F Easton Rosalind A Eeles Christopher A Haiman

Nat Genet 2014 Oct 14;46(10):1103-9. Epub 2014 Sep 14.

1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [2] Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. [3].

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http://dx.doi.org/10.1038/ng.3094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383163PMC
October 2014

Detection of an atypical teratoid rhabdoid brain tumor gene deletion in circulating blood using next-generation sequencing.

J Child Neurol 2014 Sep 17;29(9):NP81-5. Epub 2013 Oct 17.

Phoenix Children's Hospital, Phoenix, Arizona, USA TGen (Translational Genomics Institute), Phoenix, Arizona, USA

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http://dx.doi.org/10.1177/0883073813503904DOI Listing
September 2014

Open-access synthetic spike-in mRNA-seq data for cancer gene fusions.

BMC Genomics 2014 Sep 30;15:824. Epub 2014 Sep 30.

Translational Genomics Research Institute (TGen), 445 N 5th Street, SUITE 600, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1186/1471-2164-15-824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190330PMC
September 2014

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

PLoS One 2013 30;8(10):e76438. Epub 2013 Oct 30.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare (VGPCC), Scottsdale, Arizona, United States of America ; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076438PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813699PMC
August 2014

Whole-genome sequencing of an aggressive BRAF wild-type papillary thyroid cancer identified EML4-ALK translocation as a therapeutic target.

World J Surg 2014 Jun;38(6):1296-305

Translational Genomics Research Institute, 445 N. Fifth St, Phoenix, AZ, 85004, USA,

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http://dx.doi.org/10.1007/s00268-014-2485-3DOI Listing
June 2014

Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing.

Int J Gynecol Cancer 2014 Feb;24(2):329-38

*Translational Genomics Research Institute; †Comprehensive Cancer Care, St Joseph's Hospital and Medical Center, Phoenix; ‡Mayo Clinic, Scottsdale; §Department of Obstetrics and Gynecology, St Joseph's Hospital and Medical Center, and ∥Division of Gynecologic Oncology, Creighton University School of Medicine, St Joseph's Hospital and Medical Center, University of Arizona Cancer Center, Phoenix, AZ.

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http://dx.doi.org/10.1097/IGC.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921261PMC
February 2014

Long insert whole genome sequencing for copy number variant and translocation detection.

Nucleic Acids Res 2014 Jan 25;42(2):e8. Epub 2013 Sep 25.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA, Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA and Cancer Treatment Centers of America, Medical Oncology, Goodyear, AZ, 85338, USA.

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http://dx.doi.org/10.1093/nar/gkt865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902897PMC
January 2014

DNA methylation in multiple myeloma is weakly associated with gene transcription.

PLoS One 2012 20;7(12):e52626. Epub 2012 Dec 20.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, Arizona, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052626PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527579PMC
June 2013

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

Authors:
Keri L Monda Gary K Chen Kira C Taylor Cameron Palmer Todd L Edwards Leslie A Lange Maggie C Y Ng Adebowale A Adeyemo Matthew A Allison Lawrence F Bielak Guanjie Chen Mariaelisa Graff Marguerite R Irvin Suhn K Rhie Guo Li Yongmei Liu Youfang Liu Yingchang Lu Michael A Nalls Yan V Sun Mary K Wojczynski Lisa R Yanek Melinda C Aldrich Adeyinka Ademola Christopher I Amos Elisa V Bandera Cathryn H Bock Angela Britton Ulrich Broeckel Quiyin Cai Neil E Caporaso Chris S Carlson John Carpten Graham Casey Wei-Min Chen Fang Chen Yii-Der I Chen Charleston W K Chiang Gerhard A Coetzee Ellen Demerath Sandra L Deming-Halverson Ryan W Driver Patricia Dubbert Mary F Feitosa Ye Feng Barry I Freedman Elizabeth M Gillanders Omri Gottesman Xiuqing Guo Talin Haritunians Tamara Harris Curtis C Harris Anselm J M Hennis Dena G Hernandez Lorna H McNeill Timothy D Howard Barbara V Howard Virginia J Howard Karen C Johnson Sun J Kang Brendan J Keating Suzanne Kolb Lewis H Kuller Abdullah Kutlar Carl D Langefeld Guillaume Lettre Kurt Lohman Vaneet Lotay Helen Lyon Joann E Manson William Maixner Yan A Meng Kristine R Monroe Imran Morhason-Bello Adam B Murphy Josyf C Mychaleckyj Rajiv Nadukuru Katherine L Nathanson Uma Nayak Amidou N'diaye Barbara Nemesure Suh-Yuh Wu M Cristina Leske Christine Neslund-Dudas Marian Neuhouser Sarah Nyante Heather Ochs-Balcom Adesola Ogunniyi Temidayo O Ogundiran Oladosu Ojengbede Olufunmilayo I Olopade Julie R Palmer Edward A Ruiz-Narvaez Nicholette D Palmer Michael F Press Evandine Rampersaud Laura J Rasmussen-Torvik Jorge L Rodriguez-Gil Babatunde Salako Eric E Schadt Ann G Schwartz Daniel A Shriner David Siscovick Shad B Smith Sylvia Wassertheil-Smoller Elizabeth K Speliotes Margaret R Spitz Lara Sucheston Herman Taylor Bamidele O Tayo Margaret A Tucker David J Van Den Berg Digna R Velez Edwards Zhaoming Wang John K Wiencke Thomas W Winkler John S Witte Margaret Wrensch Xifeng Wu James J Yang Albert M Levin Taylor R Young Neil A Zakai Mary Cushman Krista A Zanetti Jing Hua Zhao Wei Zhao Yonglan Zheng Jie Zhou Regina G Ziegler Joseph M Zmuda Jyotika K Fernandes Gary S Gilkeson Diane L Kamen Kelly J Hunt Ida J Spruill Christine B Ambrosone Stefan Ambs Donna K Arnett Larry Atwood Diane M Becker Sonja I Berndt Leslie Bernstein William J Blot Ingrid B Borecki Erwin P Bottinger Donald W Bowden Gregory Burke Stephen J Chanock Richard S Cooper Jingzhong Ding David Duggan Michele K Evans Caroline Fox W Timothy Garvey Jonathan P Bradfield Hakon Hakonarson Struan F A Grant Ann Hsing Lisa Chu Jennifer J Hu Dezheng Huo Sue A Ingles Esther M John Joanne M Jordan Edmond K Kabagambe Sharon L R Kardia Rick A Kittles Phyllis J Goodman Eric A Klein Laurence N Kolonel Loic Le Marchand Simin Liu Barbara McKnight Robert C Millikan Thomas H Mosley Badri Padhukasahasram L Keoki Williams Sanjay R Patel Ulrike Peters Curtis A Pettaway Patricia A Peyser Bruce M Psaty Susan Redline Charles N Rotimi Benjamin A Rybicki Michèle M Sale Pamela J Schreiner Lisa B Signorello Andrew B Singleton Janet L Stanford Sara S Strom Michael J Thun Mara Vitolins Wei Zheng Jason H Moore Scott M Williams Shamika Ketkar Xiaofeng Zhu Alan B Zonderman Charles Kooperberg George J Papanicolaou Brian E Henderson Alex P Reiner Joel N Hirschhorn Ruth J F Loos Kari E North Christopher A Haiman

Nat Genet 2013 Jun 14;45(6):690-6. Epub 2013 Apr 14.

The Center for Observational Research, Amgen, Inc. Thousand Oaks, California, USA.

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http://dx.doi.org/10.1038/ng.2608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694490PMC
June 2013

Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs.

BMC Genomics 2013 May 4;14:302. Epub 2013 May 4.

Translational Genomics Research Institute, Neurogenomics Division, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1186/1471-2164-14-302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751438PMC
May 2013

Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma.

Cancer Metab 2013 May 29;1(1):14. Epub 2013 May 29.

Robert H, Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, 303 E, Superior Street, Lurie Building 3-250, Chicago, IL 606011, USA.

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http://cancerandmetabolism.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/2049-3002-1-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178207PMC
May 2013

CUL3 and NRF2 mutations confer an NRF2 activation phenotype in a sporadic form of papillary renal cell carcinoma.

Cancer Res 2013 Apr 30;73(7):2044-51. Epub 2013 Jan 30.

Interdisciplinary Renal Oncology Laboratory, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3227DOI Listing
April 2013

Racial disparities in prostate cancer incidence, biochemical recurrence, and mortality.

Prostate Cancer 2011 13;2011:716178. Epub 2011 Dec 13.

Department of Oncology, Wayne State University, Detroit, MI 48201-1379, USA.

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http://dx.doi.org/10.1155/2011/716178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238408PMC
August 2012

Differential effects of AKT1(p.E17K) expression on human mammary luminal epithelial and myoepithelial cells.

Hum Mutat 2012 Aug 11;33(8):1216-27. Epub 2012 May 11.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

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http://dx.doi.org/10.1002/humu.22100DOI Listing
August 2012

EphB2 SNPs and sporadic prostate cancer risk in African American men.

PLoS One 2011 16;6(5):e19494. Epub 2011 May 16.

Division of Integrated Cancer Genomics, Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019494PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095601PMC
October 2011

Molecular subtype analysis determines the association of advanced breast cancer in Egypt with favorable biology.

BMC Womens Health 2011 Sep 30;11:44. Epub 2011 Sep 30.

Integrated Cancer Genomics Division, Translational Genomics Research Institute, 445 N Fifth Street, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1186/1472-6874-11-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204283PMC
September 2011

Contribution of HPC1 (RNASEL) and HPCX variants to prostate cancer in a founder population.

Prostate 2010 Nov;70(15):1716-27

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1002/pros.21207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404133PMC
November 2010

DNA methylation analysis determines the high frequency of genic hypomethylation and low frequency of hypermethylation events in plasma cell tumors.

Cancer Res 2010 Sep 24;70(17):6934-44. Epub 2010 Aug 24.

The Translational Genomics Research Institute, Phoenix, AZ, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0282DOI Listing
September 2010

Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans.

Prostate 2010 Feb;70(3):270-5

Department of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1002/pros.21061DOI Listing
February 2010