John C Reed

John C Reed

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Bcl-2 on the brink of breakthroughs in cancer treatment.

Authors:
John C Reed

Cell Death Differ 2018 01;25(1):3-6

Roche, Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.

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http://dx.doi.org/10.1038/cdd.2017.188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729542PMC
January 2018

Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy.

Cancer Cell 2017 Dec;32(6):748-760.e6

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730338PMC
December 2017

Therapeutics targeting Bcl-2 in hematological malignancies.

Biochem J 2017 10 23;474(21):3643-3657. Epub 2017 Oct 23.

Roche, Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel 4070, Switzerland.

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http://dx.doi.org/10.1042/BCJ20170080DOI Listing
October 2017

Peter C. Nowell (1928-2016).

Proc Natl Acad Sci U S A 2017 05 17;114(18):4569-4570. Epub 2017 Apr 17.

Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239;

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http://dx.doi.org/10.1073/pnas.1705526114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422792PMC
May 2017

Finally, An Apoptosis-Targeting Therapeutic for Cancer.

Cancer Res 2016 10 30;76(20):5914-5920. Epub 2016 Sep 30.

Roche Pharmaceutical Research and Early Development, Basel, Switzerland. Department of Biology, ETH Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117672PMC
October 2016

Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity.

Sci Rep 2016 10 31;6:35983. Epub 2016 Oct 31.

Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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http://www.nature.com/articles/srep35983
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http://dx.doi.org/10.1038/srep35983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086849PMC
October 2016

Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress.

PLoS One 2015 18;10(6):e0130635. Epub 2015 Jun 18.

Cell Death and Survival Networks Program, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America; Pharma Research and Early Development (pRED), Roche, Basel, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130635PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472728PMC
May 2016

PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines.

PLoS One 2015 19;10(3):e0119404. Epub 2015 Mar 19.

Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119404PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366397PMC
December 2015

Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.

J Biomol Screen 2015 Dec 11;20(10):1232-45. Epub 2015 Aug 11.

Cell Death and Survival Networks Program, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA, USA Conrad Prebys Center for Chemical Genomics, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1177/1087057115600414DOI Listing
December 2015

ATG4B (Autophagin-1) phosphorylation modulates autophagy.

J Biol Chem 2015 Oct 16;290(44):26549-61. Epub 2015 Sep 16.

From the Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, California 92037, Roche, Pharmaceutical Research & Early Development, Roche Innovation Center-Basel, Basel, Switzerland CH4014

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http://www.jbc.org/content/early/2015/09/16/jbc.M115.658088.
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http://www.jbc.org/content/290/44/26549.full.pdf
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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.658088
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http://dx.doi.org/10.1074/jbc.M115.658088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646313PMC
October 2015

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2.

Retrovirology 2015 Aug 22;12:74. Epub 2015 Aug 22.

Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, USA.

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http://dx.doi.org/10.1186/s12977-015-0200-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546280PMC
August 2015

Therapeutic targeting of Bcl-2 family for treatment of B-cell malignancies.

Expert Rev Hematol 2015 Jun 25;8(3):283-97. Epub 2015 Apr 25.

Early Discovery Biochemistry Department, Genentech, South San Francisco, CA, USA.

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http://dx.doi.org/10.1586/17474086.2015.1026321DOI Listing
June 2015

Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines.

ACS Chem Neurosci 2015 Mar 17;6(3):464-75. Epub 2015 Jan 17.

†Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, and ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/cn500297vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368043PMC
March 2015

PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma.

Oncoscience 2014 5;1(10):624-33. Epub 2014 Oct 5.

Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278280PMC
http://dx.doi.org/10.18632/oncoscience.86DOI Listing
January 2015

NLRs: Sentinels of innate immunity or cancer culprits?

Oncoscience 2014 26;1(5):308-9. Epub 2014 May 26.

Sanford-Burnham Medical Research Institute, La Jolla, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278305PMC
http://dx.doi.org/10.18632/oncoscience.44DOI Listing
January 2015

PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.

Cancer Res 2014 Oct 9;74(20):5795-807. Epub 2014 Sep 9.

Sanford-Burnham Medical Research Institute, La Jolla, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199897PMC
October 2014

Dissecting the leukemogenic potency of BCLxl.

J Leuk (Los Angel) 2014;2(5):158. Epub 2014 Sep 24.

James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202 ; Department of Medicine, Division of Hematology and Oncology, University of Louisville School of Medicine, Louisville, KY 40202 ; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202.

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http://dx.doi.org/10.4172/2329-6917.1000158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666309PMC
September 2014

The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.

Nat Immunol 2014 Apr 16;15(4):343-53. Epub 2014 Feb 16.

1] Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. [2] Robert H. Lurie Comprehensive Cancer Center, Interdepartmental Immunobiology Center and Skin Disease Research Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ni.2829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123781PMC
April 2014

Reconstituting the NLRP1 inflammasome in vitro.

Methods Mol Biol 2013 ;1040:137-52

Sandford-Burnham Institute for Medical Research, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/978-1-62703-523-1_11DOI Listing
February 2014

Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs.

Mol Cancer Ther 2014 Jan 5;13(1):5-15. Epub 2013 Nov 5.

Corresponding Author: Kristiina Vuori, Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947130PMC
January 2014

ER stress-induced cell death mechanisms.

Biochim Biophys Acta 2013 Dec 10;1833(12):3460-3470. Epub 2013 Jul 10.

Sanford-Burnham Medical Research Institute, La Jolla, CA, 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2013.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834229PMC
December 2013

Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.

Bioorg Med Chem Lett 2013 Jul 14;23(14):4253-7. Epub 2013 May 14.

Program in Apoptosis and Cell Death, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.04.096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772719PMC
July 2013

Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway.

Beilstein J Org Chem 2013 8;9:900-7. Epub 2013 May 8.

Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Research Institute at Lake Nona, 6400 Sanger Road Orlando, FL 32827, USA.

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http://dx.doi.org/10.3762/bjoc.9.103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678512PMC
June 2013

Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein.

J Biol Chem 2013 May 21;288(18):12777-90. Epub 2013 Mar 21.

Sanford-Burnham Medical Research Institute, Program on Apoptosis and Cell Death Research, La Jolla, California 92037, USA.

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http://www.jbc.org/content/288/18/12777.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M112.431320
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http://dx.doi.org/10.1074/jbc.M112.431320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642323PMC
May 2013

Expedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAP.

ACS Chem Biol 2013 Apr 5;8(4):725-32. Epub 2013 Feb 5.

Program in Apoptosis and Cell Death and NCI Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1021/cb3005512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953502PMC
April 2013

Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary.

J Cancer Res Clin Oncol 2013 Feb 23;139(2):347-55. Epub 2012 Oct 23.

Department of Gynecology and Obstetrics, University Medical Center RWTH, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://link.springer.com/10.1007/s00432-012-1334-8
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http://dx.doi.org/10.1007/s00432-012-1334-8DOI Listing
February 2013

The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Biochem J 2013 Feb;449(3):613-21

Programs in Cell Death and Inflammation Research, Sanford-Burnham Medical Research Institute, 10901 N. Torrey Pines Rd, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1042/BJ20121198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966062PMC
February 2013

Targeting the Bcl-2 family for cancer therapy.

Expert Opin Ther Targets 2013 Jan 22;17(1):61-75. Epub 2012 Nov 22.

Virginia Commonwealth University, Department of Human and Molecular Genetics, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1517/14728222.2013.733001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955095PMC
January 2013

Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases.

Biosci Rep 2012 Dec;32(6):597-608

Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, U.S.A.

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http://dx.doi.org/10.1042/BSR20120055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497720PMC
December 2012

Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.

J Neurosci 2012 Oct;32(44):15565-76

Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research and Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361005, China.

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http://dx.doi.org/10.1523/JNEUROSCI.3668-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509748PMC
October 2012

Cyclosporine A and bromocriptine attenuate cell death mediated by intracellular calcium mobilization.

BMB Rep 2012 Aug;45(8):482-7

Asan Institute for Life Science, Asan Medical Center, Seoul, Korea.

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http://dx.doi.org/10.5483/BMBRep.2012.45.8.024DOI Listing
August 2012

Proteomic profiling of differentially expressed proteins from Bax inhibitor-1 knockout and wild type mice.

Mol Cells 2012 Jul 25;34(1):15-23. Epub 2012 Jun 25.

Department of Pharmacology and Cardiovascular Research Center, Chonbuk National University, Jeonju 561-182, Korea.

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http://dx.doi.org/10.1007/s10059-012-0001-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887783PMC
July 2012

CARD8 and NLRP1 undergo autoproteolytic processing through a ZU5-like domain.

PLoS One 2011 8;6(11):e27396. Epub 2011 Nov 8.

Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027396PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210808PMC
May 2012

Ironing out cell death mechanisms.

Cell 2012 May;149(5):963-5

Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674120058
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http://dx.doi.org/10.1016/j.cell.2012.05.009DOI Listing
May 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra 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Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko 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Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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January 2012

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Authors:
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