John Bradley

John Bradley

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John Bradley

John Bradley

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Frequency of Dosing of Cephalexin for Oral Step-Down Therapy of Pediatric Osteoarticular Infections Caused by Methicillin-Sensitive Staphylococcus Aureus.

Pediatr Infect Dis J 2020 06;39(6):523-525

From the Rady Children's Hospital, University of California, San Diego, CA.

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http://dx.doi.org/10.1097/INF.0000000000002661DOI Listing
June 2020

Use of pyriproxyfen in control of Aedes mosquitoes: A systematic review.

PLoS Negl Trop Dis 2020 06 12;14(6):e0008205. Epub 2020 Jun 12.

MRC Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0008205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314096PMC
June 2020

Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission.

Authors:
Lucy Rivett Sushmita Sridhar Dominic Sparkes Matthew Routledge Nick K Jones Sally Forrest Jamie Young Joana Pereira-Dias William L Hamilton Mark Ferris M Estee Torok Luke Meredith Ravi Gupta Paul A Lyons Mark Toshner Ben Warne Josefin Bartholdson Scott Claire Cormie Harmeet Gill Iain Kean Mailis Maes Nicola Reynolds Michelle Wantoch Sarah Caddy Laura Caller Theresa Feltwell Grant Hall Myra Hosmillo Charlotte Houldcroft Aminu Jahun Fahad Khokhar Anna Yakovleva Helen Butcher Daniela Caputo Debra Clapham-Riley Helen Dolling Anita Furlong Barbara Graves Emma Le Gresley Nathalie Kingston Sofia Papadia Hannah Stark Kathleen E Stirrups Jennifer Webster Joanna Calder Julie Harris Sarah Hewitt Jane Kennet Anne Meadows Rebecca Rastall Criona O Brien Jo Price Cherry Publico Jane Rowlands Valentina Ruffolo Hugo Tordesillas Karen Brookes Laura Canna Isabel Cruz Katie Dempsey Anne Elmer Naidine Escoffery Heather Jones Carla Ribeiro Caroline Saunders Angela Wright Rutendo Nyagumbo Anne Roberts Ashlea Bucke Simone Hargreaves Danielle Johnson Aileen Narcorda Debbie Read Christian Sparke Lucy Warboys Kirsty Lagadu Lenette Mactavous Tim Gould Tim Raine Claire Mather Nicola Ramenatte Anne-Laure Vallier Mary Kasanicki Penelope-Jane Eames Chris McNicholas Lisa Thake Neil Bartholomew Nick Brown Surendra Parmar Hongyi Zhang Ailsa Bowring Geraldine Martell Natalie Quinnell Jo Wright Helen Murphy Benjamin J Dunmore Ekaterina Legchenko Stefan Gräf Christopher Huang Josh Hodgson Kelvin Hunter Jennifer Martin Federica Mescia Ciara O'Donnell Linda Pointon Joy Shih Rachel Sutcliffe Tobias Tilly Zhen Tong Carmen Treacy Jennifer Wood Laura Bergamaschi Ariana Betancourt Georgie Bowyer Aloka De Sa Maddie Epping Andrew Hinch Oisin Huhn Isobel Jarvis Daniel Lewis Joe Marsden Simon McCallum Francescsa Nice Martin D Curran Stewart Fuller Afzal Chaudhry Ashley Shaw Richard J Samworth John R Bradley Gordon Dougan Kenneth Gc Smith Paul J Lehner Nicholas J Matheson Giles Wright Ian G Goodfellow Stephen Baker Michael P Weekes

Elife 2020 05 11;9. Epub 2020 May 11.

Department of Infectious Diseases, Cambridge University NHS Hospitals Foundation Trust, Cambridge, United Kingdom.

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http://dx.doi.org/10.7554/eLife.58728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314537PMC
May 2020

Key clinical research priorities for the pediatric community during the COVID-19 pandemic.

Pediatr Res 2020 May 15. Epub 2020 May 15.

Institute for Advanced Clinical Trials for Children, Rockville, MD, USA.

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http://dx.doi.org/10.1038/s41390-020-0962-yDOI Listing
May 2020

Signaling through tumor necrosis receptor 2 induces stem cell marker in CD133 regenerating tubular epithelial cells in acute cell-mediated rejection of human renal allografts.

Am J Transplant 2020 Mar 13. Epub 2020 Mar 13.

Department of Medicine, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/ajt.15846DOI Listing
March 2020

Combined Focused Ion Beam-Ultramicrotomy Method for TEM Specimen Preparation of Porous Fine-Grained Materials.

Microsc Microanal 2020 Feb;26(1):120-125

Advanced Electron Microscopy Center, Hawai'i Institute of Geophysics and Planetology, University of Hawai'i at Mānoa, 1680 East-West Road, Honolulu, HI96822, USA.

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http://dx.doi.org/10.1017/S1431927619015186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050410PMC
February 2020

Tumor necrosis factor receptor-2 signaling pathways promote survival of cancer stem-like CD133 cells in clear cell renal carcinoma.

FASEB Bioadv 2020 Feb 3;2(2):126-144. Epub 2020 Jan 3.

Department of Medicine NIHR Cambridge Biomedical Research Centre University of Cambridge Cambridge UK.

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http://dx.doi.org/10.1096/fba.2019-00071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003657PMC
February 2020

Augmented renal clearance of aminoglycosides using population-based pharmacokinetic modelling with Bayesian estimation in the paediatric ICU.

J Antimicrob Chemother 2020 01;75(1):162-169

University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, USA.

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http://dx.doi.org/10.1093/jac/dkz408DOI Listing
January 2020

Socioeconomic status is associated with physical activity in leisure time only.

Authors:
John Bradley

BMJ 2020 01 6;368:m4. Epub 2020 Jan 6.

Public Health Wales, 2 Capital Quarter, Cardiff CF10 4BZ, UK.

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http://dx.doi.org/10.1136/bmj.m4DOI Listing
January 2020

Opinion: An Existing Drug to Assess for Potential Adjunctive Therapy of Ebola Virus Disease and Post-Ebola Syndrome.

Front Pharmacol 2019 30;10:1691. Epub 2020 Jan 30.

Division of Infectious Diseases, Department of Pediatrics, UCSD School of Medicine, San Diego, CA, United States.

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http://dx.doi.org/10.3389/fphar.2019.01691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002323PMC
January 2020

Tuning the Electron Localization of Gold Enables the Control of Nitrogen-to-Ammonia Fixation.

Angew Chem Int Ed Engl 2019 Dec 4;58(51):18604-18609. Epub 2019 Nov 4.

State Key Laboratory of Chem/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, Hunan, China.

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http://dx.doi.org/10.1002/anie.201909477DOI Listing
December 2019

How delayed and non-adherent treatment contribute to onward transmission of malaria: a modelling study.

BMJ Glob Health 2019 10;4(6):e001856. Epub 2019 Dec 10.

MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1136/bmjgh-2019-001856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936434PMC
December 2019

Phenotypic and Functional Alterations in Tunneling Nanotubes Formed by Glaucomatous Trabecular Meshwork Cells.

Invest Ophthalmol Vis Sci 2019 11;60(14):4583-4595

Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States.

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http://dx.doi.org/10.1167/iovs.19-28084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827425PMC
November 2019

IgM, IgG, and IgA Influenza-Specific Plasma Cells Express Divergent Transcriptomes.

J Immunol 2019 10 9;203(8):2121-2129. Epub 2019 Sep 9.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322;

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http://dx.doi.org/10.4049/jimmunol.1900285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783370PMC
October 2019

Analysis of the RIMDAMAL trial.

Lancet 2019 09 16;394(10203):1005-1006. Epub 2019 Jul 16.

MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

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http://dx.doi.org/10.1016/S0140-6736(19)31663-0DOI Listing
September 2019

Invasive Pneumococcal Disease in Children's Hospitals: 2014-2017.

Pediatrics 2019 09 16;144(3). Epub 2019 Aug 16.

Department of Pediatrics, Pediatric Infectious Diseases Section, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1542/peds.2019-0567DOI Listing
September 2019

Estimated Prevalence and Incidence of Dry Eye Disease Based on Coding Analysis of a Large, All-age United States Health Care System.

Am J Ophthalmol 2019 06 2;202:47-54. Epub 2019 Feb 2.

Evidera|PPD, Waltham, Massachusetts, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Department of Ophthalmology & Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1016/j.ajo.2019.01.026DOI Listing
June 2019

Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management.

Diagn Microbiol Infect Dis 2019 Jun 2;94(2):188-191. Epub 2019 Feb 2.

University of California San Diego, Department of Pediatrics, Division of Critical Care.

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http://dx.doi.org/10.1016/j.diagmicrobio.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125591PMC
June 2019

Untangling the formation and liberation of water in the lunar regolith.

Proc Natl Acad Sci U S A 2019 06 20;116(23):11165-11170. Epub 2019 May 20.

Department of Chemistry, University of Hawai'i at Mānoa, Honolulu, HI 96822;

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http://dx.doi.org/10.1073/pnas.1819600116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561281PMC
June 2019

Pharmacokinetics, Safety, and Tolerability of Single-Dose Intravenous Moxifloxacin in Pediatric Patients: Dose Optimization in a Phase 1 Study.

J Clin Pharmacol 2019 05 25;59(5):654-667. Epub 2019 Jan 25.

University of California, San Diego School of Medicine and Rady Children's Hospital San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1002/jcph.1358DOI Listing
May 2019

Evaluation of Aircrew Low-Intensity Threat Laser Eye Protection.

Mil Med 2019 03;184(Suppl 1):593-603

The Henry M. Jackson Foundation for the Advancement of Military Medicine, INC., 6720A Rockledge Drive, Bethesda, MD.

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https://academic.oup.com/milmed/article/184/Supplement_1/593
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http://dx.doi.org/10.1093/milmed/usy335DOI Listing
March 2019

Dry eye disease ranking among common reasons for seeking eye care in a large US claims database.

Clin Ophthalmol 2019 1;13:225-232. Epub 2019 Feb 1.

Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.2147/OPTH.S188314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362914PMC
February 2019

The establishment of resident memory B cells in the lung requires local antigen encounter.

Nat Immunol 2019 01 3;20(1):97-108. Epub 2018 Dec 3.

Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://www.nature.com/articles/s41590-018-0260-6
Publisher Site
http://dx.doi.org/10.1038/s41590-018-0260-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392030PMC
January 2019

Concomitant diagnosis of immune deficiency and sepsis in a 19 month old with ecthyma gangrenosum by host whole-genome sequencing.

Cold Spring Harb Mol Case Stud 2018 12 17;4(6). Epub 2018 Dec 17.

Division of Infectious Disease, Department of Pediatrics, UCSD, San Diego, California 92093, USA.

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http://dx.doi.org/10.1101/mcs.a003244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318772PMC
December 2018

How house design affects malaria mosquito density, temperature, and relative humidity: an experimental study in rural Gambia.

Lancet Planet Health 2018 11;2(11):e498-e508

Department of Biosciences, Durham University, Durham, UK; Tropical Epidemiology Group and Infectious Diseases Department, London School of Hygiene & Tropical Medicine, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S25425196183023
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http://dx.doi.org/10.1016/S2542-5196(18)30234-1DOI Listing
November 2018

Optimizing Antibiotic Drug Therapy in Pediatrics: Current State and Future Needs.

J Clin Pharmacol 2018 10;58 Suppl 10:S108-S122

Department of Pediatrics, Division of Infectious Diseases, University of California at San Diego, La Jolla, CA, USA.

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http://doi.wiley.com/10.1002/jcph.1128
Publisher Site
http://dx.doi.org/10.1002/jcph.1128DOI Listing
October 2018

Antiviral treatment of childhood influenza: an update.

Curr Opin Pediatr 2018 06;30(3):438-447

Division of Pediatric Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000618DOI Listing
June 2018

Plasmodium falciparum gametocyte dynamics after pyronaridine-artesunate or artemether-lumefantrine treatment.

Malar J 2018 Jun 4;17(1):223. Epub 2018 Jun 4.

Department of Medical Microbiology, Laboratory for Clinical Parasitology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s12936-018-2373-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987563PMC
June 2018

Is stop and search a deterrent?

Authors:
John Bradley

BMJ 2018 05 16;361:k2122. Epub 2018 May 16.

Powys Public Health Team, Public Health Wales, Bronllys Hospital, Bronllys LD3 0LU, UK.

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http://dx.doi.org/10.1136/bmj.k2122DOI Listing
May 2018

Divergence in DNA Specificity among Paralogous Transcription Factors Contributes to Their Differential In Vivo Binding.

Cell Syst 2018 Apr 28;6(4):470-483.e8. Epub 2018 Mar 28.

Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27710, USA; Department of Computer Science, Duke University, Durham, NC 27708, USA; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008103PMC
April 2018

Correction of estimates of retention in care among a cohort of HIV-positive patients in Uganda in the period before starting ART: a sampling-based approach.

BMJ Open 2018 04 20;8(4):e017487. Epub 2018 Apr 20.

MRC Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2017-017487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914905PMC
April 2018

Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.

N Engl J Med 2018 03;378(11):1004-1017

From the Centre for Global Health, Institute for Infection and Immunity, St. George's University of London (S.F.M., A.L., N.S., N. Karunaharan, J.A., T.B., T.S.H.), University College London (R.S.H.), and the MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine (J.B.), London, and Liverpool School of Tropical Medicine, Liverpool (T.C., D.G.L., D.W., S.J.) - all in the United Kingdom; the University of North Carolina Project-Malawi, Kamuzu Central Hospital, Lilongwe (C. Kanyama, C.C., C.H., M.C.H.), Malawi-Liverpool-Wellcome Trust Clinical Research Programme (R.S.H., N. Kalata, K.G., M.P., J.E.) and the College of Medicine, University of Malawi (R.S.H., N. Kalata, K.G., M.P., J.E., J.J.O.), Blantyre, and Dignitas International, Zomba Central Hospital, Zomba (A.K.C., P.B., D.L., J.J.O.) - all in Malawi; University of Dschang, Dschang (C. Kouanfack), Hôpital Central Yaoundé/Site Agence Nationale de Recherche sur le Sida (ANRS) Cameroun, Yaoundé (C. Kouanfack, S. Lontsi, J.-G.N., V.S.), and Douala General Hospital (E.T., Y.N.M.) and University of Douala (Y.N.M.), Douala - all in Cameroon; the Institute for Medical Research and Training (D.C., N.S., N. Karunaharan, P.B.), University Teaching Hospital (D.C., S. Lakhi, N.S., N. Karunaharan, P.B.), and the Department of Internal Medicine and Directorate of Research and Postgraduate Studies, Lusaka Apex Medical University (P.M.), Lusaka, Zambia; the National Institute for Medical Research, Muhimbili Medical Research Centre, Dar Es Salaam, Tanzania (S.M., S. Lesikari); Institut Pasteur, Molecular Mycology Unit (E.T., O.L.), and Paris Descartes University, Necker Pasteur Center for Infectious Diseases and Tropical Medicine, IHU Imagine, Assistance Publique-Hôpitaux de Paris (O.L.), Paris; the Division of Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto (A.K.C.); and the University of North Carolina, Chapel Hill (C.H., M.C.H.).

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http://dx.doi.org/10.1056/NEJMoa1710922DOI Listing
March 2018

Trivalent flu vaccine may provide cross protection of circulating influenza B.

Authors:
John S Bradley

BMJ 2018 02 20;360:k725. Epub 2018 Feb 20.

Powys Public Health Team, Public Health Wales, Bronllys Hospital, Bronllys LD3 0LU, UK.

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http://dx.doi.org/10.1136/bmj.k725DOI Listing
February 2018