John B Patterson

John B Patterson

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John B Patterson

John B Patterson

Publications by authors named "John B Patterson"

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Pharmacological targeting of the unfolded protein response for disease intervention.

Nat Chem Biol 2019 Aug 18;15(8):764-775. Epub 2019 Jul 18.

Orinove Inc., Newbury Park, CA, USA.

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http://dx.doi.org/10.1038/s41589-019-0326-2DOI Listing
August 2019

Publisher Correction: Pharmacological targeting of the unfolded protein response for disease intervention.

Nat Chem Biol 2019 Aug 22. Epub 2019 Aug 22.

Orinove Inc., Newbury Park, CA, USA.

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http://dx.doi.org/10.1038/s41589-019-0363-xDOI Listing
August 2019

Deregulated expression of the HSP40 family members Auxilin-1 and -2 is indicative of proteostasis imbalance and predicts patient outcome in Ph(+) leukemia.

Exp Hematol Oncol 2015 9;5. Epub 2016 Feb 9.

Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1186/s40164-016-0034-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746784PMC
February 2016

Adaptation of the secretory pathway in cancer through IRE1 signaling.

Methods Mol Biol 2015 ;1292:177-94

Inserm, U1053, Université de Bordeaux, 146 rue Léo Saignat, 33000, Bordeaux, France.

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http://dx.doi.org/10.1007/978-1-4939-2522-3_13DOI Listing
December 2015

Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.

Nat Commun 2014 Aug 28;5:4202. Epub 2014 Aug 28.

1] Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5 [2] Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [3] Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1038/ncomms5202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486471PMC
August 2014

Modulation of intracellular calcium homeostasis blocks autophagosome formation.

Autophagy 2013 Oct 13;9(10):1475-90. Epub 2013 Aug 13.

Centre for Molecular Medicine Norway (NCMM); Nordic EMBL Partnership; University of Oslo, Norway; Department of Cancer Prevention and Department of Urology; Oslo University Hospitals; Oslo, Norway.

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http://dx.doi.org/10.4161/auto.25900DOI Listing
October 2013

Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.

Mol Cancer Res 2008 Aug;6(8):1268-75

Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089-9176, USA.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-08
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593417PMC
August 2008

Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment.

Cancer Res 2005 Jul;65(13):5785-91

Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, California 90089-9176, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-0754DOI Listing
July 2005