John A Todd

John A Todd

UNVERIFIED PROFILE

Are you John A Todd?   Register this Author

Register author
John A Todd

John A Todd

Publications by authors named "John A Todd"

Are you John A Todd?   Register this Author

100Publications

3234Reads

23Profile Views

Publisher Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications.

Nat Immunol 2019 Mar;20(3):375

JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41590-019-0327-z
Publisher Site
http://dx.doi.org/10.1038/s41590-019-0327-zDOI Listing
March 2019

A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease.

J Autoimmun 2018 12 13;95:1-14. Epub 2018 Nov 13.

JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; JDRF/Wellcome Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, CB2 OXY, UK. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08968411183042
Publisher Site
http://dx.doi.org/10.1016/j.jaut.2018.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284106PMC
December 2018

Evidence that UBASH3 is a causal gene for type 1 diabetes.

Authors:
John A Todd

Eur J Hum Genet 2018 07 14;26(7):925-927. Epub 2018 May 14.

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41431-018-0142-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018710PMC
July 2018

Approaches and advances in the genetic causes of autoimmune disease and their implications.

Nat Immunol 2018 07 20;19(7):674-684. Epub 2018 Jun 20.

JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41590-018-0129-8DOI Listing
July 2018

The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus.

Arthritis Res Ther 2018 07 27;20(1):152. Epub 2018 Jul 27.

Department of Medical Genetics, JDRF/Wellcome Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13075-018-1649-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062988PMC
July 2018

Allele-specific methylation of type 1 diabetes susceptibility genes.

J Autoimmun 2018 05 8;89:63-74. Epub 2017 Dec 8.

Institute of Diabetes and Obesity, Helmholtz Zentrum München, Neuherberg, Germany; Center for Regenerative Therapies - Dresden, Faculty of Medicine Carl Gustav Carus, Technische Universität, Dresden, Germany; Forschergruppe Diabetes e.V., Neuherberg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2017.11.008DOI Listing
May 2018

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

Diabetologia 2018 Jan 5;61(1):147-157. Epub 2017 Oct 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, NIHR Oxford Biomedical Research Centre, Nuffield Department of Medicine, Roosevelt Drive, Oxford, OX3 7BN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00125-017-4440-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719131PMC
January 2018

Clinical utility of single molecule counting technology for quantification of KIM-1 in patients with heart failure and chronic kidney disease.

Clin Biochem 2017 Nov 12;50(16-17):889-895. Epub 2017 Jun 12.

Vanderbilt University Medical Center, Division of Cardiovascular Medicine, Nashville, TN, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiochem.2017.06.002DOI Listing
November 2017

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.

J Autoimmun 2017 Nov 23;84:75-86. Epub 2017 Jul 23.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust/MRC Building, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2017.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656572PMC
November 2017

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

Wellcome Open Res 2017 5;2:28. Epub 2017 Oct 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus,Cambridge, CB2 0XY, UK.

View Article

Download full-text PDF

Source
https://wellcomeopenresearch.org/articles/2-28/v3
Publisher Site
http://dx.doi.org/10.12688/wellcomeopenres.11300.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531165PMC
October 2017

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.

PLoS Med 2017 Aug 1;14(8):e1002362. Epub 2017 Aug 1.

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pmed.1002362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538636PMC
August 2017

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

JCI Insight 2017 Aug 17;2(16). Epub 2017 Aug 17.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/jci.insight.93739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621870PMC
August 2017

Human IL-6RTIGIT CD4CD127CD25 T cells display potent in vitro suppressive capacity and a distinct Th17 profile.

Clin Immunol 2017 06 9;179:25-39. Epub 2017 Mar 9.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clim.2017.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471606PMC
June 2017

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment.

Data Brief 2017 Jun 2;12:676-691. Epub 2017 May 2.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dib.2017.04.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435581PMC
June 2017

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

N Engl J Med 2017 04;376(17):1615-1626

From Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato (M.S., V.O., M.L.I., M. Pitzalis, M. Pala, C.S., V.F., M.F., M. Deiana, I.A., E.P., A. Mulas, M.G.P., M. Lobina, S.L., Mara Marongiu, V.S., Michele Marongiu, G.S., F.B., A. Maschio, F.D., M. Dei, F.V., S.O., A.A., M.B.W., A. Meloni, S. Sanna, E.F., M.Z., F.C.), Center for Advanced Studies, Research, and Development in Sardinia, Parco Scientifico e Tecnologico della Sardegna (I.Z., M.F., R.C., G. Cuccuru), Struttura Complessa Disciplina di Ematologia e Centro Trapianto Cellule Staminali Emopoietiche Wilma Deplano, Ospedale Oncologico di Riferimento Regionale Armando Businco (M. Pani), Dipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, Università di Cagliari (E.C., J.F., G. Coghe, L.L., G. Fenu), Azienda Ospedaliera Brotzu, S.C. Neurologia (P.F., M. Melis), Division of Rheumatology, University and University Hospital of Cagliari (M. Piga, A. Mathieu), Department of Medical Sciences M. Aresu, University of Cagliari (D.F., S.D.G., M.G.M.), Azienda Ospedaliera Brotzu, U.S. Gastroenterologia Pediatrica Ospedale Pediatrico Microcitemico A. Cao (M.C.), and Nephrology, Dialysis, and Transplantation Unit, Giuseppe Brotzu Hospital (A.P.), Cagliari, Dipartimento di Scienze Biomediche, Università degli Studi di Sassari (M.F., F.P., F.C.), Unit of Neurology, Department of Clinical and Experimental Medicine, University of Sassari (G. Farina, G.R.), and Servizio Trasfusionale (M.A.S.) and Clinica Medica (A.D.), Azienda Ospedaliero Universitaria di Sassari, Sassari, Neurology B, Department of Neurological, Biomedical, and Movement Sciences, University of Verona, Verona (G. Farina), Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases, University of Eastern Piedmont, Novara (N.B., S.D.), SC Neurologia, Dipartimento di Scienze Mediche, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo (M. Leone), Don C. Gnocchi Foundation IRCCS (F.R.G.), and Referral Center for Systemic Autoimmune Diseases Fondazione IRCCS Cá Granda Ospedale Maggiore Policlinico and University of Milan (M. Marchini), Milan, and Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche e Ospedali Riuniti, Ancona (M.G.D.) - all in Italy; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore (M.L.I., M.G., D.S.); the Department of Clinical Neurosciences (M.B., S. Sawcer) and JDRF-Wellcome Trust Diabetes and Inflammation Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research (J.A.T.), University of Cambridge, Cambridge, United Kingdom; Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital Solna (I.K., I.L.B., T.O., J.H.), Institute of Environmental Medicine (L.A.) and Institute of Environmental Medicine, Unit of Immunology and Chronic Disease (M.E.A.R.), Karolinska Institute, and Center for Occupational and Environmental Medicine, Stockholm County Council (L.A.), Stockholm; Department of Functional Biology, University of Oviedo, Oviedo (A.S.), Rheumatology Department, Hospital Universitario 12 de Octubre, Madrid (P.E.C.), Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Seville (M.J.C.-P.), Laboratorio de Investigacion 10 and Rheumatology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela (A.G.), and Centro de Genómica e Investigación Oncológica, Pfizer-Universidad de Granada-Junta de Andalucía, Granada (M.E.A.R.) - all in Spain; Department of Human Genetics, University of Chicago, Chicago (J.H.M., J.N.); Centro Hospitalar do Porto-Hospital Santo Antonio and Unit for Multidisciplinary Research in Biomedicine-Unidade Multidisciplinar de Investigação Biomédica, Porto, Portugal (B.M.S.); Departments of Pathology and Genetics, Stanford University, Stanford, CA (S.B.M.); and Center for Statistical Genetics, University of Michigan, Ann Arbor (G.R.A.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1610528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605835PMC
April 2017

A method for identifying genetic heterogeneity within phenotypically defined disease subgroups.

Nat Genet 2017 Feb 26;49(2):310-316. Epub 2016 Dec 26.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357574PMC
February 2017

Beta-Cell Fragility As a Common Underlying Risk Factor in Type 1 and Type 2 Diabetes.

Trends Mol Med 2017 02 21;23(2):181-194. Epub 2017 Jan 21.

VIB Center for Brain & Disease Research, Leuven, Belgium; KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmed.2016.12.005DOI Listing
February 2017

Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease.

Diabetes 2016 11;65(11):3233-3239

Departments of Pathology and Pediatrics, UF Diabetes Institute, University of Florida, Gainesville, FL

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db16-0687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860440PMC
November 2016

Intolerable secretion and diabetes in tolerant transgenic mice, revisited.

Authors:
John A Todd

Nat Genet 2016 04;48(5):476-7

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Addenbrookes Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3560DOI Listing
April 2016

Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study.

BMJ Open 2015 Dec 8;5(12):e009799. Epub 2015 Dec 8.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2015-009799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679899PMC
December 2015

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

Diabetes 2015 Nov 29;64(11):3891-902. Epub 2015 Jul 29.

Department of Immunobiology, Faculty of Life Sciences & Medicine, King's College London, London, U.K. National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' National Health Service Foundation Trust and King's College London, London, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db15-0516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975524PMC
November 2015

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

Eur J Immunol 2015 Nov 1;45(11):3200-3. Epub 2015 Oct 1.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201545646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832369PMC
November 2015

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.

J Immunol 2015 Nov 5;195(10):4841-52. Epub 2015 Oct 5.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1402654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635565PMC
November 2015

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk.

Nat Genet 2015 Aug 13;47(8):898-905. Epub 2015 Jul 13.

1] Department of Medicine, Brigham and Women's Hospital, Division of Rheumatology, Immunology and Allergy, Boston, Massachusetts, USA. [2] Department of Medicine, Brigham and Women's Hospital, Division of Genetics, Harvard Medical School, Boston, Massachusetts, USA. [3] Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, USA. [4] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA. [5] Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930791PMC
August 2015

Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.

Nat Genet 2015 Jul 8;47(7):839-46. Epub 2015 Jun 8.

1] JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. [2] Medical Research Council Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754941PMC
July 2015

Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases.

Hum Mol Genet 2015 Jun 5;24(12):3305-13. Epub 2015 Mar 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK, MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddv077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498151PMC
June 2015

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

PLoS Genet 2015 Jun 24;11(6):e1005272. Epub 2015 Jun 24.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481316PMC
June 2015

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

Nat Commun 2015 May 12;6:7000. Epub 2015 May 12.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms8000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432600PMC
May 2015

IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Diabetologia 2015 Apr 6;58(4):781-90. Epub 2015 Feb 6.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, WT/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00125-015-3509-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351433PMC
April 2015

Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes.

Hum Mol Genet 2015 Mar 25;24(6):1774-90. Epub 2014 Nov 25.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK,

View Article

Download full-text PDF

Source
http://hmg.oxfordjournals.org/content/early/2014/11/25/hmg.d
Web Search
http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu581
Publisher Site
http://dx.doi.org/10.1093/hmg/ddu581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381751PMC
March 2015

Effective recruitment of participants to a phase I study using the internet and publicity releases through charities and patient organisations: analysis of the adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D).

Trials 2015 Mar 11;16:86. Epub 2015 Mar 11.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-015-0583-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369347PMC
March 2015

A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.

Genet Epidemiol 2014 Dec 4;38(8):661-70. Epub 2014 Nov 4.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.21853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258092PMC
December 2014

Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles.

J Immunol 2014 Jul 13;193(2):889-900. Epub 2014 Jun 13.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom; National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1303389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082723PMC
July 2014

Rationale and study design of the Adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D): a non-randomised, open label, adaptive dose finding trial.

BMJ Open 2014 Jun 4;4(6):e005559. Epub 2014 Jun 4.

Cambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge Institute of Public Health, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2014-005559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054640PMC
June 2014

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

BMC Genomics 2014 Apr 11;15:274. Epub 2014 Apr 11.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, CB2 0XY, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-15-274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029094PMC
April 2014

Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients.

Diabetologia 2014 Feb 22;57(2):366-72. Epub 2013 Nov 22.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00125-013-3113-8
Publisher Site
http://dx.doi.org/10.1007/s00125-013-3113-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890035PMC
February 2014

Constitutive antiviral immunity at the expense of autoimmunity.

Authors:
John A Todd

Immunity 2014 Feb;40(2):167-9

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Biomedical Research Centre, Cambridge Biomedical Campus, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2014.01.009DOI Listing
February 2014

Dimensional changes of extended-pour alginate impression materials.

Am J Orthod Dentofacial Orthop 2013 Apr;143(4 Suppl):S55-63

Department of Orthodontics, School of Dental Medicine, University of Colorado, Aurora, CO 80045, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajodo.2012.06.016DOI Listing
April 2013

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.

PLoS Genet 2013 Apr 4;9(4):e1003444. Epub 2013 Apr 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1003444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617094PMC
April 2013

Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors.

J Immunol 2013 Mar 15;190(6):2554-66. Epub 2013 Feb 15.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1202914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614027PMC
March 2013

Seven newly identified loci for autoimmune thyroid disease.

Hum Mol Genet 2012 Dec 24;21(23):5202-8. Epub 2012 Aug 24.

Department of Medical Genetics, Cambridge Institute for Medical Research, Juvenile Diabetes Research Foundation/ Wellcome Trust Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/dds357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490518PMC
December 2012

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.

Diabetes 2012 Nov 13;61(11):3012-7. Epub 2012 Aug 13.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Department of Medical Genetics, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db11-1694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478521PMC
November 2012

Extra-binomial variation approach for analysis of pooled DNA sequencing data.

Bioinformatics 2012 Nov 12;28(22):2898-904. Epub 2012 Sep 12.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
https://academic.oup.com/bioinformatics/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/bts553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496343PMC
November 2012

Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding.

PLoS Genet 2012 Sep 27;8(9):e1002982. Epub 2012 Sep 27.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1002982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459973PMC
September 2012

Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes.

Hum Mol Genet 2012 Jun 8;21(12):2815-24. Epub 2012 Mar 8.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/dds098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363338PMC
June 2012

A multifaceted evaluation of imatinib-induced cardiotoxicity in the rat.

Toxicol Pathol 2011 Dec 21;39(7):1091-106. Epub 2011 Sep 21.

Food and Drug Administration, Division of Applied Pharmacology Research, Silver Spring, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623311419524DOI Listing
December 2011

FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection.

Diabetes 2011 Nov;60(11):3081-4

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db11-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198057PMC
November 2011

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes.

Diabetes Metab Res Rev 2011 Nov;27(8):838-43

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dmrr.1259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816329PMC
November 2011

Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct.

Diabetes 2011 Oct 10;60(10):2635-44. Epub 2011 Aug 10.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetesand Inflammation Laboratory, Cambridge Institute for Medical Research, Departmentof Medical Genetics, University of Cambridge, Cambridge, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db11-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178284PMC
October 2011

Genetic analysis of adult-onset autoimmune diabetes.

Diabetes 2011 Oct 26;60(10):2645-53. Epub 2011 Aug 26.

Department of Medical Genetics, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db11-0364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178303PMC
October 2011

Metagenomics and personalized medicine.

Cell 2011 Sep;147(1):44-56

Department of Pathology and Immunology, Midwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, Washington University School of Medicine, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2011.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618802PMC
September 2011

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

PLoS Genet 2011 Aug 4;7(8):e1002216. Epub 2011 Aug 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1002216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150451PMC
August 2011

Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.

J Immunol 2011 Jul 25;187(1):325-36. Epub 2011 May 25.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1003523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128927PMC
July 2011

Baseline serum cardiac troponin I concentrations in Sprague-Dawley, spontaneous hypertensive, Wistar, Wistar-Kyoto, and Fisher rats as determined with an ultrasensitive immunoassay.

Toxicol Pathol 2011 Jun 10;39(4):653-63. Epub 2011 May 10.

Division of Applied Pharmacology Research, Food and Drug Administration, Silver Spring, Maryland 20993-0002, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623311406931DOI Listing
June 2011

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.

Diabetes 2011 May 25;60(5):1624-31. Epub 2011 Mar 25.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db10-1656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292339PMC
May 2011

Evidence of association with type 1 diabetes in the SLC11A1 gene region.

BMC Med Genet 2011 Apr 27;12:59. Epub 2011 Apr 27.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2350-12-59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114708PMC
April 2011

An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes.

Diabetes 2011 Mar 26;60(3):1041-4. Epub 2011 Jan 26.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db10
Publisher Site
http://dx.doi.org/10.2337/db10-0446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046822PMC
March 2011

T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.

Nucleic Acids Res 2011 Jan 11;39(Database issue):D997-1001. Epub 2010 Oct 11.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkq912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013780PMC
January 2011

Ten years of genetics and genomics: what have we achieved and where are we heading?

Nat Rev Genet 2010 10 7;11(10):723-33. Epub 2010 Sep 7.

INSERM U/CNRS UMR, Institut Curie - Centre de Recherche, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrg2878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004366PMC
October 2010

Reduced expression of IFIH1 is protective for type 1 diabetes.

PLoS One 2010 Sep 9;5(9). Epub 2010 Sep 9.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936573PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012646PLOS
September 2010

Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

Lancet 2010 Jul 10;376(9736):180-8. Epub 2010 Jun 10.

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(10)60588-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086761PMC
July 2010

D'oh! genes and environment cause Crohn's disease.

Authors:
John A Todd

Cell 2010 Jun;141(7):1114-6

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2010.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459541PMC
June 2010

Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.

J Immunol 2010 May 2;184(9):5075-84. Epub 2010 Apr 2.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.0903734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886967PMC
May 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Etiology of type 1 diabetes.

Authors:
John A Todd

Immunity 2010 Apr;32(4):457-67

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S107476131000126
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2010.04.001DOI Listing
April 2010