Publications by authors named "John A Tallarico"

36Publications

Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function.

Cell Chem Biol 2021 Jan 22. Epub 2021 Jan 22.

Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, Cambridge, MA 02139, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Nutritional Sciences and Toxicology, Univerity of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, Berkeley, CA 94720, USA. Electronic address:

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January 2021

Bardoxolone conjugation enables targeted protein degradation of BRD4.

Sci Rep 2020 09 23;10(1):15543. Epub 2020 Sep 23.

Department of Chemistry, University of California, Berkeley, CA, 94720, USA.

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September 2020

Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC.

Cell Chem Biol 2021 Jan 22;28(1):4-13.e17. Epub 2020 Sep 22.

Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, Berkeley, CA 94720, USA. Electronic address:

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January 2021

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.

ACS Chem Biol 2019 11 13;14(11):2430-2440. Epub 2019 May 13.

Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , California 94720 , United States.

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November 2019

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.

ACS Chem Biol 2018 04 19;13(4):1066-1081. Epub 2018 Mar 19.

Department of Systems Biology , Harvard Medical School , 200 Longwood Ave. , Boston , Massachusetts 02115 , United States.

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April 2018

DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells.

Nat Chem Biol 2014 Aug 15;10(8):623-5. Epub 2014 Jun 15.

Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.

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August 2014