Publications by authors named "John A Foekens"

100Publications

An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer.

Sci Rep 2019 09 16;9(1):13308. Epub 2019 Sep 16.

Division of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, PO box 9502, 2300, RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-49809-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746778PMC
September 2019

Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer.

Breast Cancer Res Treat 2019 Nov 6;178(2):263-274. Epub 2019 Aug 6.

Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10549-019-05380-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797661PMC
November 2019

A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy.

Breast Cancer Res 2019 07 1;21(1):77. Epub 2019 Jul 1.

Department of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s13058-019-1161-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604188PMC
July 2019

MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines.

PLoS One 2019 7;14(5):e0216400. Epub 2019 May 7.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216400PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504094PMC
January 2020

Co-regulated gene expression of splicing factors as drivers of cancer progression.

Sci Rep 2019 04 2;9(1):5484. Epub 2019 Apr 2.

Division of Drug Discovery and Safety, LACDR, Leiden University, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-40759-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445126PMC
April 2019

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2019 02;566(7742):E1

Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.

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http://www.nature.com/articles/s41586-019-0883-2
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http://dx.doi.org/10.1038/s41586-019-0883-2DOI Listing
February 2019

Mitochondrial RNA Expression and Single Nucleotide Variants in Association with Clinical Parameters in Primary Breast Cancers.

Cancers (Basel) 2018 Dec 9;10(12). Epub 2018 Dec 9.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/cancers10120500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318759PMC
December 2018

An Optimized Workflow to Evaluate Estrogen Receptor Gene Mutations in Small Amounts of Cell-Free DNA.

J Mol Diagn 2019 01 6;21(1):123-137. Epub 2018 Oct 6.

Department of Medical Oncology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands; Cancer Genomics Netherlands, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.jmoldx.2018.08.010DOI Listing
January 2019

The Predictive Value of DNA Methylation for High-Risk Breast Cancer Therapy: Current Guidelines, Medical Needs, and Challenges.

Dis Markers 2017 12;2017:4934608. Epub 2017 Sep 12.

Department of Obstetrics and Gynecology, Clinical Research Unit, Klinikum rechts der Isar, Technische Universität München, Ismaningerstr. 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1155/2017/4934608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613359PMC
June 2018

Low Tumor Mitochondrial DNA Content Is Associated with Better Outcome in Breast Cancer Patients Receiving Anthracycline-Based Chemotherapy.

Clin Cancer Res 2017 Aug 18;23(16):4735-4743. Epub 2017 Apr 18.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0032DOI Listing
August 2017

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor.

Neoplasia 2016 Nov 17;18(11):647-653. Epub 2016 Oct 17.

Erasmus MC Cancer Institute, Erasmus University Medical Center, Department of Medical Oncology and Cancer Genomics Netherlands, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.neo.2016.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071539PMC
November 2016

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.

Sci Adv 2016 Oct 7;2(10):e1601737. Epub 2016 Oct 7.

Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1126/sciadv.1601737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055383PMC
October 2016

Endocrine therapy resistance in estrogen receptor (ER)-positive breast cancer.

Drug Discov Today 2016 07 24;21(7):1181-8. Epub 2016 May 24.

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.drudis.2016.05.012DOI Listing
July 2016

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2016 06 2;534(7605):47-54. Epub 2016 May 2.

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature17676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910866PMC
June 2016

Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis.

Oncotarget 2016 May;7(20):29166-76

Department of Medical Oncology and Cancer Genomics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.8688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045386PMC
May 2016

The advantage of laser-capture microdissection over whole tissue analysis in proteomic profiling studies.

Proteomics 2016 05 28;16(10):1474-85. Epub 2016 Apr 28.

Department of Medical Oncology, Erasmus University Medical Center - Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pmic.201600004DOI Listing
May 2016

Targeted MS Assay Predicting Tamoxifen Resistance in Estrogen-Receptor-Positive Breast Cancer Tissues and Sera.

J Proteome Res 2016 Apr 18;15(4):1230-42. Epub 2016 Mar 18.

Erasmus University Medical Center Rotterdam , Erasmus MC Cancer Institute, Department of Medical Oncology, 3015 CN Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.5b01119DOI Listing
April 2016

Global proteomic characterization of microdissected estrogen receptor positive breast tumors.

Data Brief 2015 Dec 8;5:399-402. Epub 2015 Oct 8.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dib.2015.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773412PMC
December 2015

Understanding drugs in breast cancer through drug sensitivity screening.

Springerplus 2015 15;4:611. Epub 2015 Oct 15.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Postbus 2040, 's-Gravendijkwal 230, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s40064-015-1406-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628005PMC
November 2015

4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer.

Mol Oncol 2016 Jan 7;10(1):24-39. Epub 2015 Aug 7.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Wytemaweg 80, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528925PMC
January 2016

Carcinoma in situ to invasive breast cancer.

Oncoscience 2015 17;2(6):570-1. Epub 2015 Jun 17.

Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506358PMC
http://dx.doi.org/10.18632/oncoscience.170DOI Listing
August 2015

DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells.

Breast Cancer Res Treat 2015 Feb 8;149(3):693-703. Epub 2015 Feb 8.

Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1007/s10549-015-3281-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326655PMC
February 2015

mRNA expression profiles in circulating tumor cells of metastatic colorectal cancer patients.

Mol Oncol 2015 Apr 21;9(4):920-32. Epub 2015 Jan 21.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528769PMC
April 2015

Integrative analysis of genomics and proteomics data on clinical breast cancer tissue specimens extracted with acid guanidinium thiocyanate-phenol-chloroform.

J Proteome Res 2015 Mar 2;14(3):1627-36. Epub 2015 Feb 2.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam , Be401, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.5b00046DOI Listing
March 2015

Are immune signatures a worthwhile tool for decision making in early-stage human epidermal growth factor receptor 2-positive breast cancer?

J Clin Oncol 2015 Mar 20;33(7):673-5. Epub 2015 Jan 20.

Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands

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http://dx.doi.org/10.1200/JCO.2014.59.5058DOI Listing
March 2015

Growth and metastatic behavior of molecularly well-characterized human breast cancer cell lines in mice.

Breast Cancer Res Treat 2014 Nov 30;148(1):19-31. Epub 2014 Sep 30.

Department of Medical Oncology and Cancer Genomics Centre, Erasmus University Medical Center - Daniel den Hoed Cancer Center, 3000 CA, Rotterdam, The Netherlands,

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http://dx.doi.org/10.1007/s10549-014-3142-0DOI Listing
November 2014

Response.

J Natl Cancer Inst 2014 Sep 29;106(9). Epub 2014 Sep 29.

: Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CE Rotterdam, the Netherlands. *Current affiliation: Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, 6525 GA, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1093/jnci/dju254DOI Listing
September 2014

Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers.

Horm Cancer 2014 Dec 15;5(6):405-13. Epub 2014 Aug 15.

Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Dr. Molewaterplein 50, 3015 GE, Rotterdam, Netherlands.

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http://dx.doi.org/10.1007/s12672-014-0196-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228172PMC
December 2014

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Science 2014 Aug;345(6196):1251343

Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.

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http://dx.doi.org/10.1126/science.1251343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380235PMC
August 2014

Integrating meta-analysis of microarray data and targeted proteomics for biomarker identification: application in breast cancer.

J Proteome Res 2014 Jun 14;13(6):2897-909. Epub 2014 May 14.

Department of Laboratory Medicine and Pathobiology, University of Toronto , 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1021/pr500352eDOI Listing
June 2014

LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy.

Endocr Relat Cancer 2014 Feb 16;21(1):101-12. Epub 2014 Jan 16.

Departments of Radiation Oncology, Laboratory Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands Department of Medical Oncology, Erasmus MC Cancer Institute and Cancer Genomics Netherlands, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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https://erc.bioscientifica.com/downloadpdf/journals/erc/21/1
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http://www.jbc.org/content/274/18/12692
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https://erc.bioscientifica.com/view/journals/erc/21/1/101.xm
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http://dx.doi.org/10.1530/ERC-13-0183DOI Listing
February 2014

Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast cancer.

J Natl Cancer Inst 2014 Feb 7;106(2):djt376. Epub 2014 Jan 7.

Affiliations of authors: Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands (NQL, MPL, MS, RBHB, TDM, AMS, JWMM, JAF, AU); Department of Neurology (CS, TML) and Postgraduate School of Molecular Medicine (NQL, RBHB, TDM, AMS, JWMM, JAF, AU), Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Radiation Oncology (PNS) and Department of Laboratory Medicine (FCGJS), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden (BKL); Department of Oncology/Pathology, Karolinska Institute, Stockholm, Sweden (BKL); Clinical Experimental Oncology Laboratory, National Cancer Centre Giovanni Paolo II, Bari, Italy (AM, AP); Translational Cancer Research Unit, Oncology Center, GZA Hospitals St-Augustinus, Antwerp, Belgium (LYD, SJVL); Netherlands Proteomics Centre, Utrecht, The Netherlands (NQL, AU); Cancer Genomics Centre, Utrecht, The Netherlands (MS, AMS, JWMM, JAF, AU); Center for Translational Molecular Medicine, Eindhoven, The Netherlands (RBHB, JAF, AU).

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http://jnci.oxfordjournals.org/content/early/2014/01/06/jnci
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djt376
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http://dx.doi.org/10.1093/jnci/djt376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952199PMC
February 2014

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

Cancer Res 2013 Nov;73(22):6632-41

Authors' Affiliations: Department of Medical Oncology, Erasmus University Medical Center, Cancer Institute, Rotterdam; Departments of Molecular Carcinogenesis and Molecular Pathology, Central Genomic Facility, the Netherlands Cancer Institute; Agendia NV, Amsterdam, the Netherlands; and Translational Cancer Research Unit, Laboratory of Pathology, Antwerp University/Oncology Centre, GZA Hospitals St-Augustinus, Antwerp, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0704DOI Listing
November 2013

Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma.

Cell 2013 Aug;154(5):1060-1073

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.07.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974915PMC
August 2013

Quantitative proteomic analysis of microdissected breast cancer tissues: comparison of label-free and SILAC-based quantification with shotgun, directed, and targeted MS approaches.

J Proteome Res 2013 Oct 13;12(10):4627-41. Epub 2013 Sep 13.

Department of Medical Oncology, Erasmus MC Cancer Institute and ‡Department of Neurology, Erasmus University Medical Center , Dr. Molewaterplein 50, Be-401, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/pr4005794DOI Listing
October 2013

Signatures of mutational processes in human cancer.

Nature 2013 Aug 14;500(7463):415-21. Epub 2013 Aug 14.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776390PMC
August 2013

Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen.

Breast Cancer Res Treat 2013 May 17;139(1):39-49. Epub 2013 Apr 17.

Department of Medical Oncology, Erasmus MC Cancer Institute, Room Be424, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2529-7DOI Listing
May 2013

Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer.

Breast Cancer Res Treat 2013 Feb 22;138(1):47-57. Epub 2013 Jan 22.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2415-3DOI Listing
February 2013

Allele-specific, non-extendable primer blocker PCR (AS-NEPB-PCR) for DNA mutation detection in cancer.

J Mol Diagn 2013 Jan 14;15(1):62-9. Epub 2012 Nov 14.

Veridex/Ortho-Clinical Diagnostics, Johnson & Johnson, Raritan, New Jersey, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2012.08.007DOI Listing
January 2013

Proteomics pipeline for biomarker discovery of laser capture microdissected breast cancer tissue.

J Mammary Gland Biol Neoplasia 2012 Jun 30;17(2):155-64. Epub 2012 May 30.

Department of Medical Oncology and Daniel Den Hoed Cancer Center, Erasmus University Medical Center, Dr. Molewaterplein 50, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1007/s10911-012-9252-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428526PMC
June 2012

Clinical value of circulating endothelial cell detection in oncology.

Drug Discov Today 2012 Jul 24;17(13-14):710-7. Epub 2012 Jan 24.

Department of Medical Oncology, Erasmus Medical Center - Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.drudis.2012.01.011DOI Listing
July 2012

CD49f-based selection of circulating tumor cells (CTCs) improves detection across breast cancer subtypes.

Cancer Lett 2012 Jun 24;319(1):49-55. Epub 2011 Dec 24.

Erasmus MC, Department of Medical Oncology, Daniel den Hoed Cancer Center and Laboratory of Translational Tumor Immunology, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.canlet.2011.12.031DOI Listing
June 2012

Medical oncology: clinical value of circulating tumor cells in breast cancer.

Nat Rev Clin Oncol 2011 Nov 1;8(12):696-8. Epub 2011 Nov 1.

Department of Medical Oncology, Daniel den Hoed Cancer Center/Josephine Nefkens Institute and Cancer Genomics Center, Erasmus University Medical Center, 's Gravendijkwal 230, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/nrclinonc.2011.167DOI Listing
November 2011

Hormone replacement therapy dependent changes in breast cancer-related gene expression in breast tissue of healthy postmenopausal women.

Mol Oncol 2011 Dec 16;5(6):504-16. Epub 2011 Sep 16.

Department of Medical Oncology, Josephine Nefkens Institute, Cancer Genomics Centre, Erasmus Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/j.molonc.2011.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528323PMC
December 2011

Laser capture microdissection applications in breast cancer proteomics.

Methods Mol Biol 2011 ;755:143-54

Department of Medical Oncology, Center for Translational Molecular Medicine, and Cancer Genomics Centre, Erasmus MC Rotterdam, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/978-1-61779-163-5_11
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http://dx.doi.org/10.1007/978-1-61779-163-5_11DOI Listing
November 2011

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.

Breast Cancer Res Treat 2012 Jun 12;133(3):843-51. Epub 2011 Jul 12.

Department of Medical Oncology, Josephine Nefkens Institute and Daniel den Hoed Cancer Center, Erasmus MC, Building BE, Room 400, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-011-1663-3DOI Listing
June 2012

Gene expression profiling assigns CHEK2 1100delC breast cancers to the luminal intrinsic subtypes.

Breast Cancer Res Treat 2012 Apr 26;132(2):439-48. Epub 2011 May 26.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus University Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-011-1588-xDOI Listing
April 2012

Prognostic value of acquired uniparental disomy (aUPD) in primary breast cancer.

Breast Cancer Res Treat 2012 Feb 21;132(1):189-96. Epub 2011 May 21.

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Unit 1340, 1515 Holcombe Blvd, Houston, TX 77030-4009, USA.

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http://link.springer.com/content/pdf/10.1007/s10549-011-1579
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http://link.springer.com/10.1007/s10549-011-1579-y
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http://dx.doi.org/10.1007/s10549-011-1579-yDOI Listing
February 2012

Young age, increased tumor proliferation and FOXM1 expression predict early metastatic relapse only for endocrine-dependent breast cancers.

Breast Cancer Res Treat 2011 Apr 12;126(3):803-10. Epub 2011 Jan 12.

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945, USA.

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http://link.springer.com/10.1007/s10549-011-1345-1
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http://dx.doi.org/10.1007/s10549-011-1345-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337964PMC
April 2011

Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study.

Breast Cancer Res 2010 1;12(6):R103. Epub 2010 Dec 1.

Department of Medical Oncology, Josephine Nefkens Institute and Cancer Genomics Centre, Erasmus Medical Center, Rotterdam, GE, The Netherlands.

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http://dx.doi.org/10.1186/bcr2786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046448PMC
September 2011

Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes.

Breast Cancer Res Treat 2011 Jul 15;128(1):23-30. Epub 2010 Jul 15.

Department of Medical Oncology, Josephine Nefkens Institute, Erasmus MC, DR, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s10549-010-1026-5
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http://dx.doi.org/10.1007/s10549-010-1026-5DOI Listing
July 2011

MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer.

Breast Cancer Res Treat 2011 May 19;127(1):43-51. Epub 2010 May 19.

Department of Medical Oncology, Erasmus Medical Center Rotterdam, Josephine Nefkens Institute and Cancer Genomics Centre, Dr. Molewaterplein 50, Be 4.02 (lab)/4.35b (office), PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-010-0940-xDOI Listing
May 2011