Johannes M F G Aerts

Johannes M F G Aerts

UNVERIFIED PROFILE

Are you Johannes M F G Aerts?   Register this Author

Register author
Johannes M F G Aerts

Johannes M F G Aerts

Publications by authors named "Johannes M F G Aerts"

Are you Johannes M F G Aerts?   Register this Author

100Publications

2956Reads

33Profile Views

Unravelling effects of relative humidity on lipid barrier formation in human skin equivalents.

Arch Dermatol Res 2019 Nov 18;311(9):679-689. Epub 2019 Jul 18.

Department of Dermatology, Leiden University Medical Center, Albinusdreef 2, Room C3-76, 2333 ZA, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-019-01948-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787114PMC
November 2019

Adipocytes harbor a glucosylceramide biosynthesis pathway involved in iNKT cell activation.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 Aug 30;1864(8):1157-1167. Epub 2019 Apr 30.

Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2019.04.016DOI Listing
August 2019

Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease.

Neurobiol Dis 2019 07 12;127:242-252. Epub 2019 Mar 12.

School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2019.03.005DOI Listing
July 2019

Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses.

J Lipid Res 2018 12 2;59(12):2262-2276. Epub 2018 Oct 2.

Medical Biochemistry, Leiden Institute of Chemistry, Leiden, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.R086629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277158PMC
December 2018

Glycoprotein Non-Metastatic Protein B: An Emerging Biomarker for Lysosomal Dysfunction in Macrophages.

Int J Mol Sci 2018 Dec 24;20(1). Epub 2018 Dec 24.

Leiden Institute of Chemistry, Leiden University, 2333 CC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20010066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337583PMC
December 2018

Gluco-1 H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor.

J Am Chem Soc 2018 04 4;140(15):5045-5048. Epub 2018 Apr 4.

Department of Chemistry, York Structural Biology Laboratory , University of York , Heslington, York YO10 5DD , United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.8b02399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942873PMC
April 2018

In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling.

J Lipid Res 2017 12 12;58(12):2299-2309. Epub 2017 Oct 12.

Division of Drug Delivery Technology, Cluster Biotherapeutics, Leiden Academic Centre for Drug Research Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

View Article

Download full-text PDF

Source
http://www.jlr.org/lookup/doi/10.1194/jlr.M079376
Publisher Site
http://dx.doi.org/10.1194/jlr.M079376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711493PMC
December 2017

Ethnic differences in metabolite signatures and type 2 diabetes: a nested case-control analysis among people of South Asian, African and European origin.

Nutr Diabetes 2017 Dec 19;7(12):300. Epub 2017 Dec 19.

Laboratory Genetic Metabolic Diseases, Academic Medical Centre, I. van Valkengoed, Meibergdreef 9, J2-209, 1105 AZ, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41387-017-0003-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865542PMC
December 2017

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.

ACS Cent Sci 2017 Jul 13;3(7):784-793. Epub 2017 Jul 13.

Department of Bio-organic Synthesis and Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acscentsci.7b00214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532717PMC
July 2017

Is it Fabry disease?

Genet Med 2016 12 19;18(12):1181-1185. Epub 2016 May 19.

Department of Medical Biochemistry, Leiden University, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2016.55DOI Listing
December 2016

Endo-β-Glucosidase Tag Allows Dual Detection of Fusion Proteins by Fluorescent Mechanism-Based Probes and Activity Measurement.

Chembiochem 2016 09 4;17(18):1698-704. Epub 2016 Aug 4.

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden, NL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbic.201600312DOI Listing
September 2016

Investigation of original multivalent iminosugars as pharmacological chaperones for the treatment of Gaucher disease.

Carbohydr Res 2016 Jun 16;429:98-104. Epub 2016 Mar 16.

Laboratoire de Synthèse Organique et Molécules Bioactives (SYBIO), Université de Strasbourg/CNRS (UMR 7509), Ecole Européenne de Chimie, Polymères et Matériaux, 25 rue Becquerel, 67087 Strasbourg, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carres.2016.03.007DOI Listing
June 2016

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.

PLoS One 2015 14;10(8):e0135889. Epub 2015 Aug 14.

Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands; Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135889PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537125PMC
May 2016

Mechanism-based inhibitors of glycosidases: design and applications.

Adv Carbohydr Chem Biochem 2014 ;71:297-338

Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-800128-8.00004-2DOI Listing
July 2015

Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy.

J Org Chem 2015 Jul 25;80(14):7258-65. Epub 2015 Jun 25.

Gorleaus Laboratories, Leiden Institute of Chemistry, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.joc.5b00823DOI Listing
July 2015

Comparing Cyclophellitol N-Alkyl and N-Acyl Cyclophellitol Aziridines as Activity-Based Glycosidase Probes.

Chemistry 2015 Jul 12;21(30):10861-9. Epub 2015 Jun 12.

Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden (The Netherlands).

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/chem.201501313
Publisher Site
http://dx.doi.org/10.1002/chem.201501313DOI Listing
July 2015

Label-free LC-MSe in tissue and serum reveals protein networks underlying differences between benign and malignant serous ovarian tumors.

PLoS One 2014 29;9(9):e108046. Epub 2014 Sep 29.

Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108046PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180266PMC
June 2015

Development of an acid ceramidase activity-based probe.

Chem Commun (Camb) 2015 Apr;51(28):6161-3

Leiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5cc00356cDOI Listing
April 2015

Mass spectrometric quantification of glucosylsphingosine in plasma and urine of type 1 Gaucher patients using an isotope standard.

Blood Cells Mol Dis 2015 Apr 17;54(4):307-14. Epub 2015 Jan 17.

Department of Medical Biochemistry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands; Department of Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcmd.2015.01.006DOI Listing
April 2015

A sensitive gel-based method combining distinct cyclophellitol-based probes for the identification of acid/base residues in human retaining β-glucosidases.

J Biol Chem 2014 Dec 24;289(51):35351-62. Epub 2014 Oct 24.

From the Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M114.593376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271221PMC
December 2014

Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates.

Carbohydr Res 2014 Nov 18;399:26-37. Epub 2014 Jul 18.

Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2300 RA Leiden, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carres.2014.07.007DOI Listing
November 2014

Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors.

Org Biomol Chem 2014 Oct 26;12(39):7786-91. Epub 2014 Aug 26.

Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c4ob01611dDOI Listing
October 2014

Selective chaperone effect of aminocyclitol derivatives on G202R and other mutant glucocerebrosidases causing Gaucher disease.

Int J Biochem Cell Biol 2014 09 30;54:245-54. Epub 2014 Jul 30.

Research Unit on BioActive Molecules (RUBAM), Departament de Química Biomèdica, Institut de Química Avançada de Catalunya (IQAC-CSIC), Jordi Girona 18, 08034 Barcelona, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biocel.2014.07.017DOI Listing
September 2014

Glucocerebrosidase enhancers for selected Gaucher disease genotypes by modification of α-1-C-substituted imino-D-xylitols (DIXs) by click chemistry.

ChemMedChem 2014 Aug 27;9(8):1744-54. Epub 2014 Jun 27.

Departament de Genètica, Universitat de Barcelona (UB), IBUB; CIBER de Enfermedades Raras (CIBERER), Av. Diagonal 643, 08028, Barcelona (Spain).

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cmdc.201402023
Publisher Site
http://dx.doi.org/10.1002/cmdc.201402023DOI Listing
August 2014

From covalent glycosidase inhibitors to activity-based glycosidase probes.

Chemistry 2014 Aug 5;20(35):10864-72. Epub 2014 Aug 5.

Leiden Institute of Chemistry and the Netherlands Proteomics Centre, Leiden University, P.O. Box 9502, 2300 RA Leiden (The Netherlands).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201404014DOI Listing
August 2014

Potent and selective activity-based probes for GH27 human retaining α-galactosidases.

J Am Chem Soc 2014 Aug 11;136(33):11622-5. Epub 2014 Aug 11.

Leiden Institute of Chemistry and The Netherlands Proteomics Centre, Leiden University , P.O. Box 9502, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja507040nDOI Listing
August 2014

ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.

Chem Biol 2014 Aug;21(8):967-76

Departments of Chemistry and Molecular and Experimental Medicine and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chembiol.2014.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136546PMC
August 2014

Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease.

Kidney Int 2014 Jul 8;86(1):58-66. Epub 2014 Jan 8.

Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ki.2013.520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077934PMC
July 2014

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis.

J Lipid Res 2014 Jan 8;55(1):138-45. Epub 2013 Nov 8.

Lysosome and Peroxisome Biology Unit (UniLiPe), Institute of Molecular and Cell Biology (IBMC), University of Oporto, Oporto, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M043802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927471PMC
January 2014

Vascular aspects of Fabry disease in relation to clinical manifestations and elevations in plasma globotriaosylsphingosine.

Hypertension 2012 Oct 6;60(4):998-1005. Epub 2012 Aug 6.

Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.195685DOI Listing
October 2012

Tuning the leaving group in 2-deoxy-2-fluoroglucoside results in improved activity-based retaining β-glucosidase probes.

Chem Commun (Camb) 2012 Oct 29;48(84):10386-8. Epub 2012 Aug 29.

Leiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://xlink.rsc.org/?DOI=c2cc35653h
Publisher Site
http://dx.doi.org/10.1039/c2cc35653hDOI Listing
October 2012

Small fiber neuropathy in Fabry disease.

Mol Genet Metab 2012 Jun 24;106(2):135-41. Epub 2012 Mar 24.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymgme.2012.03.010DOI Listing
June 2012

Consequences of a global enzyme shortage of agalsidase beta in adult Dutch Fabry patients.

Orphanet J Rare Dis 2011 Oct 31;6:69. Epub 2011 Oct 31.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Academic Medical Centre, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1750-1172-6-69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219561PMC
October 2011

A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates.

Carbohydr Res 2011 Sep 6;346(12):1467-78. Epub 2011 Apr 6.

Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carres.2011.03.042DOI Listing
September 2011

Irreversible inhibitors and activity-based probes as research tools in chemical glycobiology.

Org Biomol Chem 2011 Sep 18;9(17):5908-26. Epub 2011 Jul 18.

Whitehead Institute For Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c1ob05531cDOI Listing
September 2011

Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies.

J Inherit Metab Dis 2011 Jun 29;34(3):605-19. Epub 2011 Mar 29.

Sphinx-Amsterdam Lysosome Center, Departments of Medical Biochemistry and Internal Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10545-011-9308-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109260PMC
June 2011

Limitations of drug registries to evaluate orphan medicinal products for the treatment of lysosomal storage disorders.

Orphanet J Rare Dis 2011 Apr 16;6:16. Epub 2011 Apr 16.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://ojrd.biomedcentral.com/articles/10.1186/1750-1172-6-1
Publisher Site
http://dx.doi.org/10.1186/1750-1172-6-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102605PMC
April 2011

The cytosolic β-glucosidase GBA3 does not influence type 1 Gaucher disease manifestation.

Blood Cells Mol Dis 2011 Jan 21;46(1):19-26. Epub 2010 Aug 21.

Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10799796100018
Publisher Site
http://dx.doi.org/10.1016/j.bcmd.2010.07.009DOI Listing
January 2011

Velaglucerase alfa.

Nat Rev Drug Discov 2010 Nov 29;9(11):837-8. Epub 2010 Oct 29.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrd3311DOI Listing
November 2010

Curdlan-mediated regulation of human phagocyte-specific chitotriosidase.

FEBS Lett 2010 Jul 10;584(14):3165-9. Epub 2010 Jun 10.

Department of Medical Biochemistry, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2010.06.001DOI Listing
July 2010

Differential expression of the EGF-TM7 family members CD97 and EMR2 in lipid-laden macrophages in atherosclerosis, multiple sclerosis and Gaucher disease.

Immunol Lett 2010 Apr 16;129(2):64-71. Epub 2010 Feb 16.

Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imlet.2010.02.004DOI Listing
April 2010

Spontaneous regression of disease manifestations can occur in type 1 Gaucher disease; results of a retrospective cohort study.

Blood Cells Mol Dis 2010 Mar 13;44(3):181-7. Epub 2010 Jan 13.

Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcmd.2009.12.006DOI Listing
March 2010

Abnormal nonstoring capillary endothelium: a novel feature of Gaucher disease. Ultrastructural study of dermal capillaries.

J Inherit Metab Dis 2010 Feb 5;33(1):69-78. Epub 2010 Jan 5.

Faculty of Medicine and General Teaching Hospital, Institute of Inherited Metabolic Disorders, Charles University in Prague, Praha, Czech Republic.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10545-009-9018-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828558PMC
February 2010

Glycosphingolipids--nature, function, and pharmacological modulation.

Angew Chem Int Ed Engl 2009 ;48(47):8848-69

Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, P.O. Box 9502, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.200902620DOI Listing
January 2010

Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase.

Bioorg Med Chem 2010 Jan 31;18(1):267-73. Epub 2009 Oct 31.

Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2009.10.060DOI Listing
January 2010

Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors.

Bioorg Med Chem Lett 2009 Dec 8;19(23):6600-3. Epub 2009 Oct 8.

Leiden Institute of Chemistry, Leiden University, Gorlaeus Laboratories, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2009.10.022DOI Listing
December 2009

Enzyme therapy for the treatment of type 1 Gaucher disease: clinical outcomes and dose - response relationships.

Expert Opin Pharmacother 2009 Nov;10(16):2641-52

Academic Medical Center, Division of Endocrinology and Metabolism, Department of Internal Medicine, F5-170, PO Box 22660, 1100 DD Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/full/10.1517/1465656090327052
Publisher Site
http://dx.doi.org/10.1517/14656560903270520DOI Listing
November 2009

Plasma markers of coagulation and endothelial activation in Fabry disease: impact of renal impairment.

Nephrol Dial Transplant 2009 Oct 10;24(10):3074-81. Epub 2009 Jun 10.

Department of Internal Medicine/Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ndt/gfp263DOI Listing
October 2009

Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates.

FEBS J 2009 Oct 2;276(19):5678-88. Epub 2009 Sep 2.

Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1742-4658.2009.07259.xDOI Listing
October 2009

Gaucher disease: a model disorder for biomarker discovery.

Expert Rev Proteomics 2009 Aug;6(4):411-9

Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/epr.09.54DOI Listing
August 2009

Increased chitotriosidase activity in serum of leprosy patients: association with bacillary leprosy.

Clin Immunol 2009 Jun;131(3):501-9

Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clim.2009.02.003DOI Listing
June 2009