Publications by authors named "Johannes Haybaeck"

100Publications

Therapeutic Potential of PI3K/AKT/mTOR Pathway in Gastrointestinal Stromal Tumors: Rationale and Progress.

Cancers (Basel) 2020 Oct 14;12(10). Epub 2020 Oct 14.

Department of Pathology, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.

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http://dx.doi.org/10.3390/cancers12102972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602170PMC
October 2020

Commentary: Discriminating α-synuclein strains in parkinson's disease and multiple system atrophy.

Front Neurosci 2020 25;14:802. Epub 2020 Aug 25.

Department of Pathology, Neuropathology and Molecular Pathology, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.3389/fnins.2020.00802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477319PMC
August 2020

Bidirectional role of NLRP3 during acute and chronic cholestatic liver injury.

Hepatology 2020 Aug 4. Epub 2020 Aug 4.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/hep.31494DOI Listing
August 2020

The Interplay of Tumor Stroma and Translational Factors in Endometrial Cancer.

Cancers (Basel) 2020 Jul 27;12(8). Epub 2020 Jul 27.

Area 2 Cancer, Center for Biomarker Research in Medicine, 8010 Graz, Austria.

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http://dx.doi.org/10.3390/cancers12082074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463731PMC
July 2020

Impact of Eukaryotic Translation Initiation Factors on Breast Cancer: Still Much to Investigate.

Cancers (Basel) 2020 Jul 21;12(7). Epub 2020 Jul 21.

Department of Pathology, Medical Faculty, Otto-von-Guericke-University Magdeburg, 39104 Magdeburg, Germany.

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http://dx.doi.org/10.3390/cancers12071984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409344PMC
July 2020

The diagnosis of primary thyroid lymphoma by fine-needle aspiration, cell block, and immunohistochemistry technique.

Diagn Cytopathol 2020 Jul 1. Epub 2020 Jul 1.

Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

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http://dx.doi.org/10.1002/dc.24526DOI Listing
July 2020

The influence of iron oxidation state on quantitative MRI parameters in post mortem human brain.

Neuroimage 2020 10 23;220:117080. Epub 2020 Jun 23.

UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada; Department of Physics & Astronomy, University of British Columbia, Vancouver, BC, Canada; Department of Pediatrics (Division of Neurology), University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2020.117080DOI Listing
October 2020

New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.

Anticancer Res 2020 Jun;40(6):3109-3118

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria

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http://dx.doi.org/10.21873/anticanres.14292DOI Listing
June 2020

Single-Measurement Multiplexed Quantification of MicroRNAs from Human Tissue Using Catalytic Hairpin Assembly and Förster Resonance Energy Transfer.

ACS Sens 2020 Jun 9;5(6):1768-1776. Epub 2020 Jun 9.

Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CNRS, CEA, 91405 Orsay Cedex, France.

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http://dx.doi.org/10.1021/acssensors.0c00432DOI Listing
June 2020

Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers.

Gastroenterology 2020 Aug 4;159(2):534-548.e11. Epub 2020 May 4.

Medical Clinic III, Gastroenterology, Metabolic diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany; Coordinating Center for alpha-1 antitrypsin deficiency-related liver disease of the European Reference Network (ERN) "Rare Liver" and the European Association for the Study of the Liver (EASL) registry group "Alpha-1 Liver," University Hospital Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.04.058DOI Listing
August 2020

Immune Checkpoint Inhibitor-induced Fatal Myositis in a Patient With Squamous Cell Carcinoma and a History of Thymoma.

Clin Lung Cancer 2020 07 28;21(4):e246-e249. Epub 2020 Jan 28.

Department of Pneumology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.cllc.2020.01.008DOI Listing
July 2020

Correction: Hepatic gene expression explains primary drug toxicity in bipolar disorder.

Transl Psychiatry 2020 Feb 17;10(1):67. Epub 2020 Feb 17.

Diagnostic & Research Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/s41398-020-0749-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026104PMC
February 2020

[Cartilage tumors: morphology, genetics, and current aspects of target therapy].

Pathologe 2020 Mar;41(2):143-152

Institut für Pathologie, Medizinische Fakultät, Otto-von-Guericke-Universität Magdeburg, Leipziger Straße 44, 39120, Magdeburg, Deutschland.

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http://dx.doi.org/10.1007/s00292-020-00752-5DOI Listing
March 2020

[Malignant round cell tumors : The Ewing sarcoma and beyond].

Pathologe 2020 Mar;41(2):116-122

Institut für Pathologie, Univ.-Klinikum Magdeburg A.ö.R., Medizinische Fakultät, Otto-von-Guericke-Universität Magdeburg, Leipziger Straße 44, 39120, Magdeburg, Deutschland.

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http://dx.doi.org/10.1007/s00292-020-00759-yDOI Listing
March 2020

promoter hypermethylation in uterine carcinosarcoma rarely coexists with mutation.

Contemp Oncol (Pozn) 2019 7;23(4):202-207. Epub 2019 Nov 7.

Department of Pathomorphology, Medical University of Gdansk, Poland.

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http://dx.doi.org/10.5114/wo.2019.89635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978758PMC
November 2019

The Communication Between the PI3K/AKT/mTOR Pathway and Y-box Binding Protein-1 in Gynecological Cancer.

Cancers (Basel) 2020 Jan 14;12(1). Epub 2020 Jan 14.

Department of Pathology, Medical Faculty Otto-von-Guericke University Magdeburg, 39120 Magdeburg, Germany.

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http://dx.doi.org/10.3390/cancers12010205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017275PMC
January 2020

Hepatic gene expression explains primary drug toxicity in bipolar disorder.

Transl Psychiatry 2019 12 9;9(1):331. Epub 2019 Dec 9.

Diagnostic & Research Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/s41398-019-0666-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901567PMC
December 2019

Jak-Stat Signaling Induced by Interleukin-6 Family Cytokines in Hepatocellular Carcinoma.

Cancers (Basel) 2019 Nov 1;11(11). Epub 2019 Nov 1.

Department of Pathology, Medical Faculty, Otto-von-Guericke-University Magdeburg, 39120 Magdeburg, Germany.

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http://dx.doi.org/10.3390/cancers11111704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896168PMC
November 2019

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells.

Biomolecules 2019 09 18;9(9). Epub 2019 Sep 18.

Department of Pathology, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, D-39120 Magdeburg, Germany.

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http://dx.doi.org/10.3390/biom9090503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769846PMC
September 2019

Optimization of ultrastructural preservation of human brain for transmission electron microscopy after long post-mortem intervals.

Acta Neuropathol Commun 2019 09 3;7(1):144. Epub 2019 Sep 3.

Research Unit Electron Microscopic Techniques, Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftigtalstrasse 6, 8010, Graz, Austria.

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http://dx.doi.org/10.1186/s40478-019-0794-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724377PMC
September 2019

Blue Light Imaging and Linked Color Imaging for the Characterization of Mucosal Changes in Chronic Gastritis: A Clinicians View and Brief Technical Report.

Dig Dis 2020 23;38(1):9-14. Epub 2019 Jul 23.

Department of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg, Germany.

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http://dx.doi.org/10.1159/000501265DOI Listing
March 2020

The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2BP2 is Overexpressed and Correlates with Poor Survival in Pancreatic Cancer.

Int J Mol Sci 2019 Jun 29;20(13). Epub 2019 Jun 29.

Department of Pharmacy, Pharmaceutical Biology, Saarland University, 66123 Saarbrücken, Germany.

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http://dx.doi.org/10.3390/ijms20133204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651604PMC
June 2019

Clinical Impact of RANK Signalling in Ovarian Cancer.

Cancers (Basel) 2019 Jun 8;11(6). Epub 2019 Jun 8.

Department of Obstetrics and Gynaecology, Medical University of Innsbruck, 6020 Innsbruck, Austria.

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https://www.mdpi.com/2072-6694/11/6/791
Publisher Site
http://dx.doi.org/10.3390/cancers11060791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627676PMC
June 2019

The influence of brain iron on myelin water imaging.

Neuroimage 2019 10 17;199:545-552. Epub 2019 May 17.

UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada; Department of Physics & Astronomy, University of British Columbia, Vancouver, BC, Canada; Department of Pediatrics (Division of Neurology), University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2019.05.042DOI Listing
October 2019

Spinal melanotic ependymoma: A case report and review of literature.

Pathol Res Pract 2019 Jul 4;215(7):152380. Epub 2019 Mar 4.

Department of Neuropathology, Diagnostic & Research Center for Molecular BioMedicine, Institute of Pathology, Medical University of Graz, Austria; Department of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, Germany; Department of Pathology, Neuropathology, and Molecular Pathology, Medical University of Innsbruck, Austria; Center for Biomarker Research in Medicine, Graz, Austria; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2019.03.009DOI Listing
July 2019

Current Coverage of the mTOR Pathway by Next-Generation Sequencing Oncology Panels.

Int J Mol Sci 2019 Feb 5;20(3). Epub 2019 Feb 5.

Department of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany.

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http://dx.doi.org/10.3390/ijms20030690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387057PMC
February 2019

Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation.

J Hepatol 2019 04 24;70(4):813-815. Epub 2019 Jan 24.

Department of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.11.018DOI Listing
April 2019

Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage.

Cytokine 2019 02 14;114:1-5. Epub 2018 Dec 14.

Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2018.11.023DOI Listing
February 2019

Advanced microRNA-based cancer diagnostics using amplified time-gated FRET.

Chem Sci 2018 Nov 11;9(42):8046-8055. Epub 2018 Sep 11.

NanoBioPhotonics , Institute for Integrative Biology of the Cell (I2BC) , Université Paris-Saclay , Université Paris-Sud , CNRS , CEA , Orsay , France . Email: ; https://www.nanofret.com.

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http://dx.doi.org/10.1039/c8sc03121eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249629PMC
November 2018

Treprostinil reduces endothelial damage in murine sinusoidal obstruction syndrome.

J Mol Med (Berl) 2019 02 7;97(2):201-213. Epub 2018 Dec 7.

Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Centre of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00109-018-1726-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348071PMC
February 2019

G-protein-coupled estrogen receptor GPER-1 expression in hormone receptor-positive breast cancer is associated with poor benefit of tamoxifen.

Breast Cancer Res Treat 2019 Feb 26;174(1):121-127. Epub 2018 Nov 26.

Department of Gynecology and Obstetrics, University Medical Center, Regensburg, Landshuter Str. 65, 93053, Regensburg, Germany.

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http://link.springer.com/10.1007/s10549-018-5064-8
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http://dx.doi.org/10.1007/s10549-018-5064-8DOI Listing
February 2019

Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.

Biochim Biophys Acta Mol Basis Dis 2019 02 9;1865(2):308-321. Epub 2018 Nov 9.

Diagnostic & Research Center for Molecular BioMedicine, Institute of Pathology, Medical University of Graz, Austria; Center for Biomarker Research in Medicine, Graz, Austria; Department of Pathology, Medical Faculty, Otto von Guericke University Magdeburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183045
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http://dx.doi.org/10.1016/j.bbadis.2018.11.006DOI Listing
February 2019

Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.

Cytokine 2019 12 30;124:154569. Epub 2018 Oct 30.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria; Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2018.10.010DOI Listing
December 2019

STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.

Cytokine 2019 12 28;124:154573. Epub 2018 Oct 28.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria; Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2018.10.014DOI Listing
December 2019

Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.

Eur J Cancer 2018 09 1;101:165-180. Epub 2018 Aug 1.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Neue Stiftingtalstrasse 6, 8010 Graz, Austria; Center for Biomarker Research in Medicine, Stiftingtalstrasse 5, 8010 Graz, Austria; Department of Pathology, Medical Faculty, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183095
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http://dx.doi.org/10.1016/j.ejca.2018.07.001DOI Listing
September 2018

Liver - master and servant of serum proteome.

J Hepatol 2018 08 28;69(2):512-524. Epub 2018 Apr 28.

Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany; The Interdisciplinary Center for Clinical Research (IZKF), University Hospital Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.04.018DOI Listing
August 2018

Therapeutic targeting of tumor-associated macrophages in pancreatic neuroendocrine tumors.

Int J Cancer 2018 10;143(7):1806-1816

Department of Internal Medicine I, Martin Luther University Halle-Wittenberg, Halle, Saale, Germany.

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http://dx.doi.org/10.1002/ijc.31562DOI Listing
October 2018

Downgrading of a G3 Neuroendocrine Tumor to a G2 Tumor: Can First-Line Cytotoxic Chemotherapy Change the Tumor Biology?

Case Rep Oncol 2017 Sep-Dec;10(3):1121-1126. Epub 2017 Dec 20.

Clinical Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1159/000484473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803685PMC
December 2017

Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling.

J Hepatol 2018 05 11;68(5):996-1005. Epub 2018 Jan 11.

Department of Internal Medicine III, RWTH University Hospital Aachen, Germany; Interdisciplinary Center for Clinical Research (IZKF), RWTH University Hospital Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.01.003DOI Listing
May 2018

Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in mutant mesenchymal-like NSCLC cells.

Sci Signal 2017 Sep 12;10(496). Epub 2017 Sep 12.

Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1126/scisignal.aam6291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657393PMC
September 2017

Homer1a protein expression in schizophrenia, bipolar disorder, and major depression.

J Neural Transm (Vienna) 2017 10 16;124(10):1261-1273. Epub 2017 Aug 16.

Laboratory of Brain Research and Neuropathology, The Stanley Medical Research Institute, Bethesda, USA.

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http://dx.doi.org/10.1007/s00702-017-1776-xDOI Listing
October 2017

Adult morphea en coup de sabre with accompanying regional polymyositis: A separate entity?

Australas J Dermatol 2018 May 21;59(2):e145-e146. Epub 2017 Jul 21.

Department of Dermatology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1111/ajd.12612DOI Listing
May 2018

New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.

Eur J Cancer 2017 09 14;83:56-70. Epub 2017 Jul 14.

Department of Pathology, Medical University of Graz, Austria; Center for Biomarker Research in Medicine, Graz, Austria; Department of Pathology, Otto-von-Guericke-University Magdeburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.06.003DOI Listing
September 2017

Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.

Clin Chem 2017 Sep 30;63(9):1497-1505. Epub 2017 Jun 30.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden;

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http://dx.doi.org/10.1373/clinchem.2017.271833DOI Listing
September 2017

High neuronatin (NNAT) expression is associated with poor outcome in breast cancer.

Virchows Arch 2017 Jul 24;471(1):23-30. Epub 2017 May 24.

Department of Pathology, Otto von Guericke University Magdeburg, Leipziger Str. 44, D-39120, Magdeburg, Germany.

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http://dx.doi.org/10.1007/s00428-017-2154-7DOI Listing
July 2017

New Diagnostic and Therapeutic Aspects of Pancreatic Ductal Adenocarcinoma.

Curr Med Chem 2017 ;24(28):3012-3024

Department of Pathology, Otto-von- Guericke University of Magdeburg, Magdeburg. Germany.

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http://dx.doi.org/10.2174/0929867324666170510150124DOI Listing
December 2017

Native Oligodendrocytes in Astrocytomas Might Inhibit Tumor Proliferation by WIF1 Expression.

J Neuropathol Exp Neurol 2017 01;76(1):16-26

Department of Neuropathology, Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1093/jnen/nlw098DOI Listing
January 2017

Histological parameters and alcohol abstinence determine long-term prognosis in patients with alcoholic liver disease.

J Hepatol 2017 03 25;66(3):610-618. Epub 2016 Nov 25.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1016/j.jhep.2016.11.011DOI Listing
March 2017

Pancreatic resection for intraductal papillary mucinous neoplasm- a thirteen-year single center experience.

BMC Cancer 2016 11 4;16(1):844. Epub 2016 Nov 4.

Department of General Surgery, Medical University of Graz, Auenbruggerplatz 29, A-8036, Graz, Austria.

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http://dx.doi.org/10.1186/s12885-016-2887-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096332PMC
November 2016

Expression of SOX11, PAX5, TTF-1 and ISL-1 in medulloblastoma.

Pathol Res Pract 2016 Nov 11;212(11):965-971. Epub 2016 Aug 11.

Department of Pathomorphology, Medical University of Gdansk, Poland.

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http://dx.doi.org/10.1016/j.prp.2016.08.006DOI Listing
November 2016

Insulin-Like Growth Factor 2 - The Oncogene and its Accomplices.

Curr Pharm Des 2016 ;22(39):5948-5961

Department of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbrücken 66123, Germany.

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http://dx.doi.org/10.2174/1381612822666160713100235DOI Listing
December 2017