Publications by authors named "Johannes D Veldhuis"

100Publications

Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way.

Endocr Connect 2020 Jul;9(7):637-648

Endocrine Research Unit, Mayo Clinic College of Medicine, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1530/EC-20-0211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424344PMC
July 2020

Kisspeptin and neurokinin B interactions in modulating gonadotropin secretion in women with polycystic ovary syndrome.

Hum Reprod 2020 Jun;35(6):1421-1431

MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1093/humrep/deaa104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316500PMC
June 2020

Age and time-of-day differences in the hypothalamo-pituitary-testicular, and adrenal, response to total overnight sleep deprivation.

Sleep 2020 Jul;43(7)

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1093/sleep/zsaa008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355405PMC
July 2020

Dapagliflozin restores insulin and growth hormone secretion in obese mice.

J Endocrinol 2020 04;245(1):1-12

School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia.

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http://dx.doi.org/10.1530/JOE-19-0385DOI Listing
April 2020

Dynamic Interactions Between LH and Testosterone in Healthy Community-Dwelling Men: Impact of Age and Body Composition.

J Clin Endocrinol Metab 2020 03;105(3)

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1210/clinem/dgz246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025815PMC
March 2020

Regulation and adaptation of endocrine axes at high altitude.

Am J Physiol Endocrinol Metab 2020 02 26;318(2):E297-E309. Epub 2019 Nov 26.

Women's University Hospital, Department of Gynecological endocrinology and Reproductive Medicine, Berne, Switzerland.

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http://dx.doi.org/10.1152/ajpendo.00243.2019DOI Listing
February 2020

A novel measure of glucose homeostasis (or loss thereof) comprising the joint dynamics of glucose, insulin, glucagon, and cortisol.

Am J Physiol Endocrinol Metab 2019 06 12;316(6):E998-E1011. Epub 2019 Mar 12.

Division of Endocrinology, Center of Diabetes Technology, University of Virginia School of Medicine , Charlottesville, Virginia.

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http://dx.doi.org/10.1152/ajpendo.00078.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620575PMC
June 2019

Modulating Effects of Progesterone on Spontaneous Nocturnal and Ghrelin-Induced GH Secretion in Postmenopausal Women.

J Clin Endocrinol Metab 2019 06;104(6):2385-2394

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1210/jc.2018-02639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505453PMC
June 2019

Feedback on LH in Testosterone-Clamped Men Depends on the Mode of Testosterone Administration and Body Composition.

J Endocr Soc 2019 Jan 23;3(1):235-249. Epub 2018 Nov 23.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1210/js.2018-00317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320245PMC
January 2019

Estradiol Does Not Influence Lipid Measures and Inflammatory Markers in Testosterone-Clamped Healthy Men.

J Endocr Soc 2018 Aug 29;2(8):882-892. Epub 2018 Jun 29.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1210/js.2018-00141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055532PMC
August 2018

Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men.

J Clin Endocrinol Metab 2018 12;103(12):4419-4427

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1210/jc.2018-00755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212797PMC
December 2018

Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women.

J Endocr Soc 2018 Jul 14;2(7):794-805. Epub 2018 Jun 14.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1210/js.2018-00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030831PMC
July 2018

Effects of Toremifene, a Selective Estrogen Receptor Modulator, on Spontaneous and Stimulated GH Secretion, IGF-I, and IGF-Binding Proteins in Healthy Elderly Subjects.

J Endocr Soc 2018 Feb 28;2(2):154-165. Epub 2017 Dec 28.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/js.2017-00457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789038PMC
February 2018

Neurokinin B Regulates Gonadotropin Secretion, Ovarian Follicle Growth, and the Timing of Ovulation in Healthy Women.

J Clin Endocrinol Metab 2018 01;103(1):95-104

MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1210/jc.2017-01306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761486PMC
January 2018

Neurokinin 3 receptor antagonism decreases gonadotropin and testosterone secretion in healthy men.

Clin Endocrinol (Oxf) 2017 Dec 5;87(6):748-756. Epub 2017 Sep 5.

MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/cen.13445DOI Listing
December 2017

Impact of age, sex and body mass index on cortisol secretion in 143 healthy adults.

Endocr Connect 2017 Oct 31;6(7):500-509. Epub 2017 Jul 31.

Endocrine Research UnitMayo Medical and Graduate Schools, Clinical Translational Research Center, Mayo Clinic, Rochester, Minnesota, USA

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http://dx.doi.org/10.1530/EC-17-0160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597974PMC
October 2017

Hypothalamo-pituitary-adrenal axis after a single epidural triamcinolone injection.

Endocrine 2017 Aug 3;57(2):308-313. Epub 2017 Jul 3.

Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s12020-017-1357-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554884PMC
August 2017

Enhanced Coupling Within Gonadotropic and Adrenocorticotropic Axes by Moderate Exercise in Healthy Men.

J Clin Endocrinol Metab 2017 07;102(7):2482-2490

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/jc.2017-00036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505190PMC
July 2017

Regulation of Pulsatile and Entropic ACTH Secretion Under Fixed Exogenous Secretagogue Clamps.

J Clin Endocrinol Metab 2017 07;102(7):2611-2619

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55902.

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http://dx.doi.org/10.1210/jc.2017-00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505204PMC
July 2017

Effects of transdermal testosterone gel or an aromatase inhibitor on serum concentration and pulsatility of growth hormone in older men with age-related low testosterone.

Metabolism 2017 Apr 19;69:143-147. Epub 2017 Jan 19.

Section on Men's Health, Aging and Metabolism, Brigham and Women's Hospital Harvard Medical School, Boston, MA, United States, 02115. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950718PMC
April 2017

Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice.

Reproduction 2017 03;153(3):267-276

School of Biomedical ScienceUniversity of Queensland, St Lucia, Brisbane, Queensland, Australia

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http://dx.doi.org/10.1530/REP-16-0341DOI Listing
March 2017

Pulsatile Cortisol Feedback on ACTH Secretion Is Mediated by the Glucocorticoid Receptor and Modulated by Gender.

J Clin Endocrinol Metab 2016 11 22;101(11):4094-4102. Epub 2016 Aug 22.

Department of Endocrinology and Metabolism (F.R.), Leiden University Medical Center, 2300 RC Leiden, The Netherlands; and Endocrine Research Unit (P.A., J.D.V.), Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/jc.2016-2405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095237PMC
November 2016

Endogenous Estrogen Regulates Somatostatin-Induced Rebound GH Secretion in Postmenopausal Women.

J Clin Endocrinol Metab 2016 11 26;101(11):4298-4304. Epub 2016 Jul 26.

Endocrine Research Unit (J.D.V., D.E., R.Y.), Mayo Clinic College of Medicine, Center for Translational Science Activities, Mayo Clinic, and Department of Primary Care Internal Medicine (P.T.), Mayo Clinic, Rochester, Minnesota 55905; and Tulane University Health Sciences Center (C.B.), Endocrinology and Metabolism Section, Peptide Research Section, New Orleans, Louisiana 70112.

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http://dx.doi.org/10.1210/jc.2016-2080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095244PMC
November 2016

Interactions Between Neurokinin B and Kisspeptin in Mediating Estrogen Feedback in Healthy Women.

J Clin Endocrinol Metab 2016 12 16;101(12):4628-4636. Epub 2016 Sep 16.

MRC Centre for Reproductive Health (K.S., J.T.G., R.A.A.), The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom; Endocrine Research Unit (J.D.V.), Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905; and Mammal Research Unit and Centre for Neuroendocrinology (R.P.M.), University of Pretoria, 0028 Pretoria, South Africa and MRC Receptor Biology Unit, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, 7925 Observatory, South Africa.

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http://dx.doi.org/10.1210/jc.2016-2132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155690PMC
December 2016

Mild pituitary phenotype in 3- and 12-month-old Aip-deficient male mice.

J Endocrinol 2016 10;231(1):59-69

Institut National de la Santé et de la Recherche Médicale (Inserm) U1185Le Kremlin-Bicêtre, France Université Paris-SudFaculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France Assistance Publique-Hôpitaux de ParisService d'Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, Le Kremlin Bicêtre, France

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http://dx.doi.org/10.1530/JOE-16-0190DOI Listing
October 2016

Interleukins 6 and 8 and abdominal fat depots are distinct correlates of lipid moieties in healthy pre- and postmenopausal women.

Endocrine 2016 Dec 22;54(3):671-680. Epub 2016 Jul 22.

Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s12020-016-1041-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107333PMC
December 2016

Investigating the KNDy Hypothesis in Humans by Coadministration of Kisspeptin, Neurokinin B, and Naltrexone in Men.

J Clin Endocrinol Metab 2016 09 5;101(9):3429-36. Epub 2016 Jul 5.

Section of Investigative Medicine (S.N., J.K.P., C.N.J., D.A.P., M.M., A.J.S., A.N.C., A.A., S.R.B., W.S.D.), Imperial College London, Hammersmith Hospital, London W12 ONN, United Kingdom; Statsconsultancy Ltd (P.B.), Amersham, Buckinghamshire HP7 9EN, United Kingdom; and Endocrine Research Unit (J.D.V.), Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/jc.2016-1911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010567PMC
September 2016

Optimizing Blood Sampling Protocols in Patients With Acromegaly for the Estimation of Growth Hormone Secretion.

J Clin Endocrinol Metab 2016 07 29;101(7):2675-82. Epub 2016 Mar 29.

Department of Internal Medicine, Section of Endocrinology and Metabolism (F.R., N.R.B., A.M.P.), Leiden University Medical Center, Leiden, the Netherlands; and Endocrine Research Unit (J.D.V.), Center for Translational Science Activities, Mayo Clinic College of Medicine, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/jc.2016-1142DOI Listing
July 2016

Pulsatility of Hypothalamo-Pituitary Hormones: A Challenge in Quantification.

Physiology (Bethesda) 2016 Jan;31(1):34-50

Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1152/physiol.00027.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698454PMC
January 2016

Impact of Adiposity and Fat Distribution on the Dynamics of Adrenocorticotropin and Cortisol Rhythms.

Curr Obes Rep 2014 Dec;3(4):387-95

Endocrine Research Unit, Mayo Medical and Graduate Schools, Clinical Translational Research Center, Mayo Clinic, Rochester, MN, 55901, USA.

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http://dx.doi.org/10.1007/s13679-014-0118-7DOI Listing
December 2014

Growth Hormone Dynamics in Healthy Adults Are Related to Age and Sex and Strongly Dependent on Body Mass Index.

Neuroendocrinology 2016 28;103(3-4):335-44. Epub 2015 Jul 28.

Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1159/000438904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731317PMC
May 2017

Multipathway modulation of exercise and glucose stress effects upon GH secretion in healthy men.

Metabolism 2015 Sep 15;64(9):1022-30. Epub 2015 May 15.

Endocrine Research Unit, Mayo Clinic College of Medicine, Center for Translational Science Activities.

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http://dx.doi.org/10.1016/j.metabol.2015.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546548PMC
September 2015

Somatostatin is essential for the sexual dimorphism of GH secretion, corticosteroid-binding globulin production, and corticosterone levels in mice.

Endocrinology 2015 Mar 31;156(3):1052-65. Epub 2014 Dec 31.

Neuroscience Graduate Program (J.M.A.), University of Michigan, Ann Arbor, Michigan, 48109; Department of Molecular and Integrative Physiology (J.M.A., V.O.-C., M.J.L.), University of Michigan Medical School, Ann Arbor, Michigan, 48109; Department of Cellular and Physiological Sciences (G.L.H.), University of British Columbia, Vancouver, British Columbia, Canada, V6T 1Z3; Department of Internal Medicine (J.D.V.), Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905; and Department of Internal Medicine (N.Q., M.J.L.), Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan, 48109.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2014-1429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330306PMC
March 2015

Estrogen-like potentiation of ghrelin-stimulated GH secretion by fulvestrant, a putatively selective ER antagonist, in postmenopausal women.

J Clin Endocrinol Metab 2014 Dec;99(12):E2557-64

Endocrine Research Unit (J.D.V., R.J.Y., J.R.W., D.E., J.C.M.), Mayo Clinic College of Medicine Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905; and Tulane University Health Sciences Center (C.Y.B.), Endocrinology and Metabolism Section, Peptide Research Section, New Orleans, Louisiana 70112.

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http://dx.doi.org/10.1210/jc.2014-2633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255109PMC
December 2014

Hormone secretion by pituitary adenomas is characterized by increased disorderliness and spikiness but more regular pulsing.

J Clin Endocrinol Metab 2014 Oct 11;99(10):3836-44. Epub 2014 Jul 11.

Department of Endocrinology and Metabolic Diseases (F.R., A.M.P., N.R.B.), Leiden University Medical Center, 2333ZA Leiden, The Netherlands; and Endocrine Research Unit (J.D.V.), Mayo Medical and Graduate Schools, Clinical Translational Research Center, Mayo Clinic, Rochester, Minnesota 55901.

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http://dx.doi.org/10.1210/jc.2014-2363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184075PMC
October 2014

An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth.

Endocrinology 2014 Sep 20;155(9):3561-71. Epub 2014 Jun 20.

Unité Mixte de Recherche en Santé 894 (R.H., P.Z., O.F., A.L., J.C., J.E., V.T.), INSERM, Centre de Psychiatrie et Neurosciences, Université Paris Descartes, Sorbonne Paris Cité, 75014 Paris, France; School of Biomedical Sciences (F.S., C.C.), University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; Unité Mixte de Recherche 7104 (C.T.), Centre National de la Recherche Scientifique/ Unité 596, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, 67404 Illkirch, France; and Department of Medicine (J.D.V.), Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/en.2014-1126DOI Listing
September 2014

Continuous positive airway pressure increases pulsatile growth hormone secretion and circulating insulin-like growth factor-1 in a time-dependent manner in men with obstructive sleep apnea: a randomized sham-controlled study.

Sleep 2014 Apr 1;37(4):733-41. Epub 2014 Apr 1.

NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research, University of Sydney, Glebe, NSW, Australia ; Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Los Angeles, CA.

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http://dx.doi.org/10.5665/sleep.3580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044752PMC
April 2014

Immunologic and mass-spectrometric estimates of SHBG concentrations in healthy women.

Metabolism 2014 Jun 21;63(6):783-92. Epub 2014 Mar 21.

Laboratory Medicine and Pathology, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905.

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http://dx.doi.org/10.1016/j.metabol.2014.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066221PMC
June 2014

Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women.

Am J Physiol Regul Integr Comp Physiol 2014 May 26;306(9):R627-35. Epub 2014 Feb 26.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota.

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http://www.physiology.org/doi/10.1152/ajpregu.00551.2013
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http://dx.doi.org/10.1152/ajpregu.00551.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010660PMC
May 2014

Reduced nocturnal ACTH-driven cortisol secretion during critical illness.

Am J Physiol Endocrinol Metab 2014 Apr 25;306(8):E883-92. Epub 2014 Feb 25.

Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, and.

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http://dx.doi.org/10.1152/ajpendo.00009.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989736PMC
April 2014

Increasing LH pulsatility in women with hypothalamic amenorrhoea using intravenous infusion of Kisspeptin-54.

J Clin Endocrinol Metab 2014 Jun 11;99(6):E953-61. Epub 2014 Feb 11.

Section of Investigative Medicine (C.N.J., A.A., A.N.C., R.R., A.D.S., G.M.K.N., Z.G.-D., M.A.G., S.R.B., W.S.D.), Imperial College London, Hammersmith Hospital, London W12 ONN, United Kingdom; and Endocrine Research Unit (J.D.V.), Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905; and Department of Imaging (A.M., C.T.), Imperial College Healthcare National Health Service Trust, Charing Cross Hospital, London W6 8RF, United Kingdom.

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http://dx.doi.org/10.1210/jc.2013-1569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207927PMC
June 2014

Corticotropic axis drive of overnight cortisol secretion is suppressed in adolescents and young adults with type 1 diabetes mellitus.

Pediatr Diabetes 2014 Sep 18;15(6):444-52. Epub 2013 Dec 18.

Children's Hospital Central California, Madera, CA, 93636-8762, USA; Endocrine Research Unit, Center for Translational Science Activities, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1111/pedi.12108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062617PMC
September 2014

Thyrotropin secretion in healthy subjects is robust and independent of age and gender, and only weakly dependent on body mass index.

J Clin Endocrinol Metab 2014 Feb 25;99(2):570-8. Epub 2013 Nov 25.

Department of Endocrinology and Metabolism (F.R., H.P., P.K., N.R.B., A.M.P.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Department of Endocrinology (E.E., E.F.), Amsterdam Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands; and Endocrine Research Unit (J.D.V.), Mayo Clinic College of Medicine, Rochester, Minnesota 55905.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2013-2858DOI Listing
February 2014

Short-term estradiol supplementation potentiates low-dose ghrelin action in the presence of GHRH or somatostatin in older women.

J Clin Endocrinol Metab 2014 Jan 20;99(1):E73-80. Epub 2013 Dec 20.

Endocrine Research Unit (C.N., S.M.W., J.R.W., D.E., J.M.M., J.D.V.), Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905; Naval Medical Center Portsmouth (N.R.), Division of Reproductive Endocrinology, Portsmouth, Virginia 23708; and Tulane University Health Sciences Center (C.Y.B.), Endocrinology and Metabolism Section, Peptide Research Section, New Orleans, Louisiana 70112.

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http://dx.doi.org/10.1210/jc.2013-3043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879681PMC
January 2014

Immunological and mass spectrometric assays of SHBG: consistent and inconsistent metabolic associations in healthy men.

J Clin Endocrinol Metab 2014 Jan 20;99(1):184-93. Epub 2013 Dec 20.

Endocrine Research Unit (J.D.V.), Mayo School of Graduate Medical Education Center for Translational Science Activities, Immunochemical Laboratory (R.B.D.), and Departments of Neurology (S.A.T.) and Laboratory Medicine and Pathology (J.D.V., O.P.B., E.W.K., R.J.S., G.G.K.), Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1210/jc.2013-2642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879680PMC
January 2014

Effects of neurokinin B administration on reproductive hormone secretion in healthy men and women.

J Clin Endocrinol Metab 2014 Jan 20;99(1):E19-27. Epub 2013 Dec 20.

Section of Investigative Medicine (C.N.J., A.N.C., A.D.S., A.A., G.M.K.N., Z.G.-D., M.V., M.A.G., S.R.B., W.S.D.), Imperial College London, Hammersmith Hospital, London W12 ONN, United Kingdom; Endocrine Research Unit (J.D.V.), Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905; and Department of Histopathology (G.S.), Royal Marsden Hospital, London SW3 6JJ, United Kingdom.

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http://dx.doi.org/10.1210/jc.2012-2880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952021PMC
January 2014

Estradiol regulates GH-releasing peptide's interactions with GH-releasing hormone and somatostatin in postmenopausal women.

Eur J Endocrinol 2014 Jan 29;170(1):121-9. Epub 2013 Nov 29.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1530/EJE-13-0733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892701PMC
January 2014

Gender determines ACTH recovery from hypercortisolemia in healthy older humans.

Metabolism 2013 Dec 25;62(12):1819-29. Epub 2013 Sep 25.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.metabol.2013.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860097PMC
December 2013

Age-dependent and gender-dependent regulation of hypothalamic-adrenocorticotropic-adrenal axis.

Endocrinol Metab Clin North Am 2013 Jun 13;42(2):201-25. Epub 2013 Mar 13.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.ecl.2013.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675779PMC
June 2013

Thyrotropin secretion patterns in health and disease.

Endocr Rev 2013 Oct 10;34(5):619-57. Epub 2013 Apr 10.

Leiden University Medical Center, Department of Endocrinology and Metabolic Diseases, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1210/er.2012-1076DOI Listing
October 2013

Differential pulsatile secretagogue control of GH secretion in healthy men.

Am J Physiol Regul Integr Comp Physiol 2013 May 13;304(9):R712-9. Epub 2013 Mar 13.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajpregu.00069.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652074PMC
May 2013

Changes in pituitary function with ageing and implications for patient care.

Nat Rev Endocrinol 2013 Apr 26;9(4):205-15. Epub 2013 Feb 26.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/nrendo.2013.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920108PMC
April 2013

Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism.

Clin Endocrinol (Oxf) 2013 Jul 19;79(1):100-4. Epub 2013 Apr 19.

MRC Centre for Reproductive Health, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.

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July 2013

Analysis of the impact of intravenous LH pulses versus continuous LH infusion on testosterone secretion during GnRH-receptor blockade.

Am J Physiol Regul Integr Comp Physiol 2012 Nov 19;303(10):R994-R1002. Epub 2012 Sep 19.

Endocrine Research Unit, Dept. of Internal Medicine, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517669PMC
November 2012

Sex steroids, GHRH, somatostatin, IGF-I, and IGFBP-1 modulate ghrelin's dose-dependent drive of pulsatile GH secretion in healthy older men.

J Clin Endocrinol Metab 2012 Dec 18;97(12):4753-60. Epub 2012 Sep 18.

Endocrine Research Unit, Mayo School of Graduate Medical Education, National Institutes of Health Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/jc.2012-2567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513533PMC
December 2012

Modeling the Nonlinear Time Dynamics of Multidimensional Hormonal Systems.

J Time Ser Anal 2012 Sep 21;33(5):779-796. Epub 2012 Jun 21.

Department of Statistics, University of Virginia, Charlottesville, Va 22904.

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http://dx.doi.org/10.1111/j.1467-9892.2012.00795.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437937PMC
September 2012

Model-based evaluation of growth hormone secretion.

Methods Enzymol 2012 ;514:231-48

Department of Medicine, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota, USA.

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February 2013

Diminished adrenal sensitivity and ACTH efficacy in obese premenopausal women.

Eur J Endocrinol 2012 Nov 21;167(5):633-42. Epub 2012 Aug 21.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, The Netherlands.

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November 2012

Dynamic testosterone responses to near-physiological LH pulses are determined by the time pattern of prior intravenous LH infusion.

Am J Physiol Endocrinol Metab 2012 Sep 17;303(6):E720-8. Epub 2012 Jul 17.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1152/ajpendo.00200.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468430PMC
September 2012

Logistic model of glucose-regulated C-peptide secretion: hysteresis pathway disruption in impaired fasting glycemia.

Am J Physiol Endocrinol Metab 2012 Aug 5;303(3):E397-409. Epub 2012 Jun 5.

Department of Statistics, University of Virginia, Charlottesville, VA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423124PMC
August 2012

Gonadotropin-inhibitory hormone (GnIH) secretion into the ovine hypophyseal portal system.

Endocrinology 2012 Jul 1;153(7):3368-75. Epub 2012 May 1.

Department of Physiology, Building 13F, Monash University, Clayton, Victoria 3880, Australia.

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http://dx.doi.org/10.1210/en.2012-1088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380300PMC
July 2012

Distinct metabolic surrogates predict basal and rebound GH secretion after glucose ingestion in men.

J Clin Endocrinol Metab 2012 Jun 3;97(6):2172-9. Epub 2012 Apr 3.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/jc.2011-3317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387415PMC
June 2012

Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals.

J Clin Endocrinol Metab 2012 May 7;97(5):E791-5. Epub 2012 Mar 7.

Division of Diabetology and Gastrointestinal Endocrinology, St. Josef-Hospital, Ruhr-University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany.

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http://dx.doi.org/10.1210/jc.2011-3439DOI Listing
May 2012

Prolactin secretion in healthy adults is determined by gender, age and body mass index.

PLoS One 2012 17;7(2):e31305. Epub 2012 Feb 17.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281966PMC
June 2012

Glucose ingestion acutely lowers pulsatile LH and basal testosterone secretion in men.

Am J Physiol Endocrinol Metab 2012 Mar 17;302(6):E724-30. Epub 2012 Jan 17.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajpendo.00520.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311294PMC
March 2012

Noninvasive analytical estimation of endogenous GnRH drive: analysis using graded competitive GnRH-receptor antagonism and a calibrating pulse of exogenous GnRH.

Endocrinology 2011 Dec 25;152(12):4882-93. Epub 2011 Oct 25.

Department of Statistics, University of Virginia, Charlottesville, Virginia 22904, USA.

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http://dx.doi.org/10.1210/en.2011-1461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230048PMC
December 2011

Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men.

Am J Physiol Endocrinol Metab 2012 Jan 4;302(1):E117-22. Epub 2011 Oct 4.

Endocrine Research Unit, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajpendo.00450.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328086PMC
January 2012

Endogenous ACTH concentration-cortisol secretion dose analysis unmasks decreased ACTH potency in Cushing's disease with restoration after successful pituitary adenomectomy.

J Clin Endocrinol Metab 2011 Dec 14;96(12):3768-74. Epub 2011 Sep 14.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1210/jc.2011-1878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410358PMC
December 2011

Oscillations in joint synchrony of reproductive hormones in healthy men.

Am J Physiol Endocrinol Metab 2011 Dec 6;301(6):E1163-73. Epub 2011 Sep 6.

Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1152/ajpendo.00138.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233781PMC
December 2011

Regulated recovery of pulsatile growth hormone secretion from negative feedback: a preclinical investigation.

Am J Physiol Regul Integr Comp Physiol 2011 Oct 27;301(4):R1143-52. Epub 2011 Jul 27.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajpregu.00293.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197337PMC
October 2011

Glucose ingestion selectively amplifies ACTH and cortisol secretory-burst mass and enhances their joint synchrony in healthy men.

J Clin Endocrinol Metab 2011 Sep 13;96(9):2882-8. Epub 2011 Jul 13.

Endocrine Section, Medical Service, Salem Veterans Affairs Medical Center, Salem, Virginia 24153, USA.

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http://dx.doi.org/10.1210/jc.2011-0682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167666PMC
September 2011

Tripartite control of dynamic ACTH-cortisol dose responsiveness by age, body mass index, and gender in 111 healthy adults.

J Clin Endocrinol Metab 2011 Sep 13;96(9):2874-81. Epub 2011 Jul 13.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/jc.2011-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167672PMC
September 2011

Impaired adrenergic- and corticotropic-axis outflow during exercise in chronic obstructive pulmonary disease.

Metabolism 2011 Nov 31;60(11):1521-9. Epub 2011 May 31.

Endocrine Service, Medical Section, Salem Veterans Affairs Medical Center, Salem, VA 24153, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002604951100083
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http://dx.doi.org/10.1016/j.metabol.2011.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181386PMC
November 2011

Gender, sex-steroid, and secretagogue-selective recovery from growth hormone-induced feedback in older women and men.

J Clin Endocrinol Metab 2011 Aug 25;96(8):2540-7. Epub 2011 May 25.

Endocrine Research Unit, Mayo School of Graduate Medical Education Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/jc.2011-0298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146792PMC
August 2011

Overnight ACTH-cortisol dose responsiveness: comparison with 24-h data, metyrapone administration and insulin-tolerance test in healthy adults.

Clin Endocrinol (Oxf) 2011 Nov;75(5):596-601

Department of Medicine, Endocrine Section, Salem Veterans Affairs Medical Center, Salem, VA, USA.

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http://dx.doi.org/10.1111/j.1365-2265.2011.04125.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287347PMC
November 2011

Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp.

Am J Physiol Endocrinol Metab 2011 Jun 5;300(6):E1158-65. Epub 2011 Apr 5.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, MayoClinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajpendo.00054.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118586PMC
June 2011

Altered multihormone synchrony in obese patients with polycystic ovary syndrome.

Metabolism 2011 Sep 26;60(9):1227-33. Epub 2011 Jan 26.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Albinusdreef 2, 2333ZA, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.metabol.2010.12.011DOI Listing
September 2011

Analytical construct of reversible desensitization of pituitary-testicular signaling: illustrative application in aging.

Am J Physiol Regul Integr Comp Physiol 2011 Feb 17;300(2):R349-60. Epub 2010 Nov 17.

Department of Statistics, University of Virginia, Charlottesville, USA.

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http://dx.doi.org/10.1152/ajpregu.00477.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043799PMC
February 2011

Gender, age, body mass index, and IGF-I individually and jointly determine distinct GH dynamics: analyses in one hundred healthy adults.

J Clin Endocrinol Metab 2011 Jan 6;96(1):115-21. Epub 2010 Oct 6.

Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/jc.2010-1669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038492PMC
January 2011

Integrating GHS into the Ghrelin System.

Int J Pept 2010 18;2010. Epub 2010 Mar 18.

Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1155/2010/879503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925380PMC
July 2011

Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.

Am J Physiol Endocrinol Metab 2010 Oct 3;299(4):E675-82. Epub 2010 Aug 3.

Mayo School of Graduate Medical Education, Mayo Clinic, 200 First St. SW/Mayo Clinic, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957871PMC
October 2010

Effects of testosterone administration on nocturnal cortisol secretion in healthy older men.

J Gerontol A Biol Sci Med Sci 2010 Nov 30;65(11):1185-92. Epub 2010 Jul 30.

Diabetes Unit, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1093/gerona/glq128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954240PMC
November 2010

Regulation of complex pulsatile and rhythmic neuroendocrine systems: the male gonadal axis as a prototype.

Prog Brain Res 2010 ;181:79-110

Department of Medicine, Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota, United States of America.

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August 2010

A pegylated growth hormone receptor antagonist, pegvisomant, does not enter the brain in humans.

J Clin Endocrinol Metab 2010 Aug 5;95(8):3844-7. Epub 2010 May 5.

Endocrine Research Unit, Department of Neurology, Mayo School of Graduate Medical Education, Clinical Translation Research Center, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1210/jc.2010-0538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913040PMC
August 2010

Dose-response downregulation within the span of single interpulse intervals.

Am J Physiol Regul Integr Comp Physiol 2010 Jul 21;299(1):R11-8. Epub 2010 Apr 21.

Department of Statistics, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1152/ajpregu.00201.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904156PMC
July 2010

Age in men does not determine gonadotropin-releasing hormone's dose-dependent stimulation of luteinizing hormone secretion under an exogenous testosterone clamp.

J Clin Endocrinol Metab 2010 Jun 31;95(6):2877-84. Epub 2010 Mar 31.

Endocrine Section, Department of Medicine, Salem Veterans Affairs Medical Center, Salem, Virginia 24153, USA.

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http://dx.doi.org/10.1210/jc.2009-2581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902075PMC
June 2010

Secretagogue type, sex-steroid milieu, and abdominal visceral adiposity individually determine secretagogue-stimulated cortisol secretion.

Eur J Endocrinol 2010 Jun 18;162(6):1043-9. Epub 2010 Mar 18.

Endocrine Section, Department of Medicine, Salem Veterans Affairs Medical Center, Salem, Virginia 24153, USA.

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http://dx.doi.org/10.1530/EJE-10-0149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108036PMC
June 2010

Kinetics of removal of intravenous testosterone pulses in normal men.

Eur J Endocrinol 2010 Apr 20;162(4):787-94. Epub 2010 Jan 20.

Endocrine Research Unit, Mayo School of Graduate Medical Education, Clinical Translational Science Center, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1530/EJE-09-1085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861557PMC
April 2010