Johannes Beckers

Johannes Beckers

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Johannes Beckers

Publications by authors named "Johannes Beckers"

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Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.

Exp Eye Res 2019 Nov 13;188:107632. Epub 2019 Apr 13.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144835183070
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http://dx.doi.org/10.1016/j.exer.2019.03.024DOI Listing
November 2019

Point mutations in the PDX1 transactivation domain impair human β-cell development and function.

Mol Metab 2019 Jun 20;24:80-97. Epub 2019 Mar 20.

Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Institute of Stem Cell Research, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Technische Universität München, Ismaningerstraße 22, 81675 München, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531841PMC
June 2019

The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease.

EBioMedicine 2019 May 4;43:562-575. Epub 2019 May 4.

Comprehensive Pneumology Center (CPC), Institute of Lung Biology and Disease, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.03.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562022PMC
May 2019

The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis.

Cell Rep 2018 12;25(12):3241-3251.e5

Institute of Stem Cell Research, Helmholtz Center Munich, 85764 Neuherberg, Germany; Department for Cell Biology and Anatomy, Biomedical Center of LMU, 82152 Planegg, Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183181
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http://dx.doi.org/10.1016/j.celrep.2018.11.055DOI Listing
December 2018

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Behav Brain Res 2018 10 29;352:187-196. Epub 2017 Sep 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.09.048DOI Listing
October 2018

A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice.

Nutrients 2018 Apr 28;10(5). Epub 2018 Apr 28.

Division of Pathobiochemistry and Clinical Chemistry, Department of Internal Medicine IV, University Hospital Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.3390/nu10050547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986427PMC
April 2018

Animal models of obesity and diabetes mellitus.

Nat Rev Endocrinol 2018 03 19;14(3):140-162. Epub 2018 Jan 19.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nrendo.2017.161DOI Listing
March 2018

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.

Mol Metab 2018 03 31;9:57-68. Epub 2018 Jan 31.

Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, Parkring 11, 85748, Garching, Germany; Institute of Stem Cell Research, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Chair of ß-Cell Biology, Technische Universität München, Ismaningerstraße 22, 81675 München, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870105PMC
March 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation.

Immunology 2017 11 28;152(3):402-413. Epub 2017 Jul 28.

Comprehensive Pneumology Centre, Helmholtz Zentrum München, University Hospital of the Ludwig Maximilians University, Member of the German Centre for Lung Research, Munich, Germany.

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http://dx.doi.org/10.1111/imm.12775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629441PMC
November 2017

Pulmonary CCR2CD4 T cells are immune regulatory and attenuate lung fibrosis development.

Thorax 2017 11 5;72(11):1007-1020. Epub 2017 Aug 5.

Comprehensive Pneumology Center, Helmholtz Center Munich Germany, Member of the German Center for Lung Research (DZL), Munich, Germany.

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http://dx.doi.org/10.1136/thoraxjnl-2016-208423DOI Listing
November 2017

Modeling coexistence of oscillation and Delta/Notch-mediated lateral inhibition in pancreas development and neurogenesis.

J Theor Biol 2017 10 23;430:32-44. Epub 2017 Jun 23.

Institute of Experimental Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany; Chair of Experimental Genetics, School of Life Sciences Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2017.06.006DOI Listing
October 2017

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

Authors:
Rhea van den Bruck Patrick P Weil Thomas Ziegenhals Philipp Schreiner Stefan Juranek Daniel Gödde Silvia Vogel Frauke Schuster Valerie Orth Johannes Dörner Daniel Pembaur Meike Röper Stefan Störkel Hubert Zirngibl Stefan Wirth Andreas C W Jenke Jan Postberg Nikolas Boy Jana Heringer Gisela Haege Esther M Glahn Georg F Hoffmann Sven F Garbade Peter Burgard Stefan Kölker Cho-Ming Chao Faady Yahya Alena Moiseenko Amit Shrestha Negah Ahmadvand Jennifer Quantius Jochen Wilhelm Elie El-Agha Klaus-Peter Zimmer Saverio Bellusci Christian Staufner Stefan Kölker Holger Prokisch Georg F Hoffmann Stephan Seeliger Matthias Müller Andreas Hippe Henrik Steinkraus Roland Wauer Burkhard Lachmann Sigrun R Hofmann Christian M Hedrich Jakob Zierk Farhad Arzideh Rainer Haeckel Wolfgang Rascher Manfred Rauh Markus Metzler Sebastian Thieme Joanna Bandoła Cornelia Richter Martin Ryser Arshad Jamal Michelle P Ashton Malte von Bonin Matthias Kuhn Christian M Hedrich Ezio Bonifacio Reinhard Berner Sebastian Brenner Johanna Hammersen Cristina Has Nora Naumann-Bartsch Daniel Stachel Dimitra Kiritsi Stephan Söder Mathilde Tardieu Markus Metzler Leena Bruckner-Tuderman Holm Schneider F Bohne D Langer R Cencic T Eggermann U Zechner J Pelletier F Zepp T Enklaar D Prawitt Martin Pech Markus Weckmann Femke-Anouska Heinsen Andre Franke Christine Happle Anna-Maria Dittrich Gesine Hansen Oliver Fuchs Erika von Mutius Brian G Oliver Matthias V Kopp Claudia Paret Alexandra Russo Johanna Theruvath Bettina Keller Khalifa El Malki Nadine Lehmann Arthur Wingerter Marie A Neu Gerhold-Ay Aslihan Wolfgang Wagner Clemens Sommer Torsten Pietsch Larissa Seidmann Jörg Faber Felix Schreiner Merle Ackermann Michael Michalik Eva Rother Andras Bilkei-Gorzo Ildiko Racz Laura Bindila Beat Lutz Jörg Dötsch Andreas Zimmer Joachim Woelfle Hendrik S Fischer Tim L Ullrich Christoph Bührer Christoph Czernik Gerd Schmalisch Robert Stein Sigrun R Hofmann Judith Hagenbuchner Ursula Kiechl-Kohlendorfer Petra Obexer Michael J Ausserlechner Niki T Loges Adrien Tobias Frommer Julia Wallmeier Heymut Omran Soner Öner-Sieben Martina Gimpfl Jan Rozman Martin Irmler Johannes Beckers Martin Hrabe De Angelis Adelbert Roscher Eckhard Wolf Regina Ensenauer Karolina Nemes Michael Frühwald Martin Hasselblatt Reiner Siebert Uwe Kordes Marcel Kool Haicui Wang Holly Hardy Osama Refai Katy E S Barwick Holly H Zimmerman Joachim Weis Emma L Baple Andrew H Crosby Sebahattin Cirak C Hellmuth O Uhl M Standl J Heinrich E Thiering B Koletzko Lena Blümel Kornelius Kerl Daniel Picard Michael C Frühwald Max C Liebau Guido Reifenberger Arndt Borkhardt Martin Hasselblatt Marc Remke D Tews M Wabitsch P Fischer-Posovszky Mike-Andrew Westhoff Lisa Nonnenmacher Julia Langhans Lukas Schneele Nancy Trenkler Klaus-Michael Debatin

Mol Cell Pediatr 2017 May;4(Suppl 1)

Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1186/s40348-017-0071-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435609PMC
May 2017

Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo.

Endocr Relat Cancer 2017 01 3;24(1):1-15. Epub 2016 Nov 3.

Institute for Diabetes and CancerHelmholtz Zentrum München, Neuherberg, Germany

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http://dx.doi.org/10.1530/ERC-16-0324DOI Listing
January 2017

Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.

Part Fibre Toxicol 2017 01 10;14(1). Epub 2017 Jan 10.

Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Ingolstädter Landstr. 1, D-85764, Neuherberg, Germany.

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http://dx.doi.org/10.1186/s12989-016-0181-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223553PMC
January 2017

Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: a targeted proteomics approach.

Arch Physiol Biochem 2016 Dec 5;122(5):281-288. Epub 2016 Aug 5.

a Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen , Tübingen , Germany.

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http://dx.doi.org/10.1080/13813455.2016.1212898DOI Listing
December 2016

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle.

Diabetes 2016 10 29;65(10):2849-61. Epub 2016 Jun 29.

Division of Endocrinology, Diabetology, Angiology, Nephrology, Pathobiochemistry and Clinical Chemistry, Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Zentrum München, University of Tübingen, Tübingen, Germany German Center for Diabetes Research (DZD), Neuherberg, Germany

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http://dx.doi.org/10.2337/db15-1723DOI Listing
October 2016

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.

Diabetes 2016 09 9;65(9):2540-52. Epub 2016 Jun 9.

Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany German Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany Center of Life and Food Sciences Weihenstephan, Technische Universität München, Freising, Germany

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http://diabetes.diabetesjournals.org/content/diabetes/early/
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http://dx.doi.org/10.2337/db15-1670DOI Listing
September 2016

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines.

PLoS One 2015 11;10(8):e0134503. Epub 2015 Aug 11.

Helmholtz Zentrum München GmbH, German Mouse Clinic, Institute of Experimental Genetics, D-85764 Neuherberg, Germany; Technische Universität München, Chair of Experimental Genetics, D-85354 Freising, Germany; German Center for Diabetes Research (DZD), D-85764 Neuherberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134503PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532500PMC
May 2016

Epigenetic germline inheritance of diet-induced obesity and insulin resistance.

Nat Genet 2016 05 14;48(5):497-9. Epub 2016 Mar 14.

Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1038/ng.3527DOI Listing
May 2016

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming.

Cell Stem Cell 2016 Mar 31;18(3):396-409. Epub 2015 Dec 31.

Physiological Genomics, Biomedical Center Ludwig-Maximilians-University Munich, 80336 Munich, Germany; Institute for Stem Cell Research, Helmholtz Center Munich, 85764 Neuherberg, Germany; Excellence Cluster of Systems Neurology (SYNERGY), 80336 Munich, Germany. Electronic address:

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http://www.cell.com/cell-stem-cell/pdf/S1934-5909(15)00548-2
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http://linkinghub.elsevier.com/retrieve/pii/S193459091500548
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http://dx.doi.org/10.1016/j.stem.2015.12.003DOI Listing
March 2016

The global gene expression profile of the secondary transition during pancreatic development.

Mech Dev 2016 Feb 28;139:51-64. Epub 2015 Nov 28.

Institute of Diabetes and Regeneration Research, Institute of Stem Cell Research, Helmholtz Zentrum München, Business Campus Garching, Parkring 11, 85748 Garching, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; Faculty of Medicine, Technische Universität München, Ismaninger Str. 22, 81675 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mod.2015.11.004DOI Listing
February 2016

Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring.

Mamm Genome 2016 Feb 11;27(1-2):17-28. Epub 2015 Dec 11.

Institute of Experimental Genetics and German Mouse Clinic, Helmholtz Zentrum München GmbH - German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-015-9616-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731435PMC
February 2016

Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.

Arch Biochem Biophys 2016 Jan 25;589:93-107. Epub 2015 Sep 25.

Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany; Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising-Weihenstephan, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2015.09.013DOI Listing
January 2016

Quantification of regenerative potential in primary human mammary epithelial cells.

Development 2015 Sep 12;142(18):3239-51. Epub 2015 Jun 12.

Institute of Stem Cell Research, Helmholtz Center for Health and Environmental Research Munich, Neuherberg 85764, Germany

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http://dx.doi.org/10.1242/dev.123554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582177PMC
September 2015

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis.

Glia 2015 Aug 12;63(8):1452-68. Epub 2015 May 12.

Institute of Experimental Genetics, Helmholtz Center Munich, Munich, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029574PMC
http://dx.doi.org/10.1002/glia.22850DOI Listing
August 2015

Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery.

Diabetologia 2015 Aug 12;58(8):1845-54. Epub 2015 Jun 12.

Centre of Inflammation and Metabolism, Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00125-015-3584-xDOI Listing
August 2015

Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay.

Sci Rep 2015 Aug 5;5:12673. Epub 2015 Aug 5.

Comprehensive Pneumology Center, University Hospital of the Ludwig-Maximilians-University Munich and Helmholtz Zentrum München, Member of the German Center for Lung Research, 81377 Munich, Germany.

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http://dx.doi.org/10.1038/srep12673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525140PMC
August 2015

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes.

Cell Stem Cell 2015 Jul 25;17(1):74-88. Epub 2015 Jun 25.

Physiological Genomics, Biomedical Center, University of Munich, 80336 Munich, Germany; Institute for Stem Cell Research, Helmholtz Centre Munich, 85764 Neuherberg, Germany; Munich Cluster for Systems Neurology "SyNergy," Ludwig Maximilian University of Munich, 80539 Munich, Germany. Electronic address:

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http://www.cell.com/cell-stem-cell/pdf/S1934-5909(15)00223-4
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http://linkinghub.elsevier.com/retrieve/pii/S193459091500223
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http://dx.doi.org/10.1016/j.stem.2015.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509553PMC
July 2015

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes.

Mol Metab 2015 Jul 1;4(7):519-27. Epub 2015 May 1.

German Centre for Diabetes Research (DZD), Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany ; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Otfried-Müller-Straße 10, D-72076 Tübingen, Germany ; Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, University Hospital Tübingen, Otfried-Müller-Straße 10, D-72076 Tübingen, Germany.

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http://dx.doi.org/10.1016/j.molmet.2015.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481465PMC
July 2015

MiR-34a deficiency accelerates medulloblastoma formation in vivo.

Int J Cancer 2015 May 25;136(10):2293-303. Epub 2014 Nov 25.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Hufelandstr. 55 45147, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29294DOI Listing
May 2015

Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus.

Neuropsychopharmacology 2015 Jan 18;40(2):338-49. Epub 2014 Jul 18.

1] Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal [2] ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.

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http://dx.doi.org/10.1038/npp.2014.176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443946PMC
January 2015

Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.

Diabetes 2015 Jan 28;64(1):284-90. Epub 2014 Jul 28.

Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany German Center for Diabetes Research, Neuherberg/Munich, Germany Technische Universität München-Weihenstephan, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.2337/db14-0393DOI Listing
January 2015

Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation.

Cell Rep 2015 Jan 8;10(2):131-9. Epub 2015 Jan 8.

Institute of Stem Cell Research, Helmholtz Center for Health and Environmental Research Munich, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.12.032DOI Listing
January 2015

Peroxidasin is essential for eye development in the mouse.

Hum Mol Genet 2014 Nov 3;23(21):5597-614. Epub 2014 Jun 3.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany, German Mouse Clinic, Neuherberg, Germany,

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http://hmg.oxfordjournals.org/content/early/2014/06/16/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu274
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http://dx.doi.org/10.1093/hmg/ddu274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189897PMC
November 2014

Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD.

Am J Physiol Lung Cell Mol Physiol 2014 Nov 15;307(9):L692-706. Epub 2014 Aug 15.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München, Member of the German Center for Lung Research, Neuherberg, Germany;

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http://www.physiology.org/doi/10.1152/ajplung.00092.2014
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http://dx.doi.org/10.1152/ajplung.00092.2014DOI Listing
November 2014

Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation.

Cell Rep 2014 Nov 13;9(4):1292-305. Epub 2014 Nov 13.

Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; German Center for Infection Research (DZIF), partner site Munich, 81675 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.044DOI Listing
November 2014

Fast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition.

PLoS Comput Biol 2014 Oct 2;10(10):e1003843. Epub 2014 Oct 2.

Institute of Experimental Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany; Technische Universität München, Center of Life and Food Sciences Weihenstephan, Chair of Experimental Genetics, Freising, Germany.

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https://dx.plos.org/10.1371/journal.pcbi.1003843
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http://dx.doi.org/10.1371/journal.pcbi.1003843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196275PMC
October 2014

Pitx3 directly regulates Foxe3 during early lens development.

Int J Dev Biol 2013 ;57(9-10):741-51

Helmholtz Center Munich, Institute of Developmental Genetics, Neuherberg, Germany.

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http://dx.doi.org/10.1387/ijdb.130193jgDOI Listing
September 2014

Prdm6 is essential for cardiovascular development in vivo.

PLoS One 2013 21;8(11):e81833. Epub 2013 Nov 21.

Institut für Klinische Chemie und Pathobiochemie, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany ; German Cancer Consortium (DKTK), Heidelberg, Germany ; German Cancer Research Center (DKFZ), Heidelberg, Germany ; Laboratory of Signaling in the Immune System, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081833PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836774PMC
August 2014

Simple derivation of transgene-free iPS cells by a dual recombinase approach.

Mol Biotechnol 2014 Aug;56(8):697-713

Institute of Developmental Genetics, Helmholtz Zentrum München, 85764, Munich, Germany,

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http://dx.doi.org/10.1007/s12033-014-9748-yDOI Listing
August 2014

Secretome profiling of primary human skeletal muscle cells.

Biochim Biophys Acta 2014 May 27;1844(5):1011-7. Epub 2013 Aug 27.

Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Duesseldorf, Germany; German Center for Diabetes Research (DZD), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2013.08.004DOI Listing
May 2014

Liver adapts mitochondrial function to insulin resistant and diabetic states in mice.

J Hepatol 2014 Apr 28;60(4):816-23. Epub 2013 Nov 28.

Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, University of Köln, 50931 Köln, Germany; Center for Molecular Medicine Cologne, CMMC, University of Köln, 50931 Köln, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50674 Köln, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2013.11.020DOI Listing
April 2014

Differential kinetics of antigen dependency of CD4+ and CD8+ T cells.

J Immunol 2014 Apr 17;192(8):3507-17. Epub 2014 Mar 17.

Institute for Immunology, Ludwig-Maximilians-University Munich, 80336 Munich, Germany;

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http://dx.doi.org/10.4049/jimmunol.1302725DOI Listing
April 2014

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis.

Mol Metab 2013 3;2(4):435-46. Epub 2013 Aug 3.

Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany ; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764 Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1016/j.molmet.2013.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855089PMC
December 2013

Cytokine response of primary human myotubes in an in vitro exercise model.

Am J Physiol Cell Physiol 2013 Oct 7;305(8):C877-86. Epub 2013 Aug 7.

Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany;

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http://dx.doi.org/10.1152/ajpcell.00043.2013DOI Listing
October 2013

Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors.

J Clin Endocrinol Metab 2013 Jun 30;98(6):E1137-42. Epub 2013 Apr 30.

Division of Endocrinology, Diabetology, Angiology, Nephrology, Pathobiochemistry, and Clinical Chemistry, Department of Internal Medicine, University Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1210/jc.2012-3976DOI Listing
June 2013

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells.

Cell Mol Life Sci 2013 May 31;70(9):1637-51. Epub 2013 Jan 31.

Department of Experimental Medicine, Biotechnology and Molecular Biology Section, Second University of Naples, Naples, Italy.

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http://link.springer.com/10.1007/s00018-012-1224-x
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http://dx.doi.org/10.1007/s00018-012-1224-xDOI Listing
May 2013

The transcription factor Otx2 regulates choroid plexus development and function.

Development 2013 Mar 30;140(5):1055-66. Epub 2013 Jan 30.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute for Stem Cell Research, Neuherberg, 85764 Munich, Germany.

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http://dx.doi.org/10.1242/dev.090860DOI Listing
March 2013

From dynamic expression patterns to boundary formation in the presomitic mesoderm.

PLoS Comput Biol 2012 28;8(6):e1002586. Epub 2012 Jun 28.

Institute of Experimental Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1002586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386180PMC
October 2012

Innovations in phenotyping of mouse models in the German Mouse Clinic.

Mamm Genome 2012 Oct 29;23(9-10):611-22. Epub 2012 Aug 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1007/s00335-012-9415-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463795PMC
October 2012

Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part II: gene regulation.

Cell Reprogram 2012 Feb 28;14(1):68-78. Epub 2011 Dec 28.

Genetic Reprogramming Group, Agricultural Biotechnology Center, Gödöllő, Hungary.

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http://dx.doi.org/10.1089/cell.2011.0057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275096PMC
February 2012

Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation.

Respir Res 2011 Jul 15;12:94. Epub 2011 Jul 15.

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1186/1465-9921-12-94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145576PMC
July 2011