Johanna M Seddon

Johanna M Seddon

UNVERIFIED PROFILE

Are you Johanna M Seddon?   Register this Author

Register author
Johanna M Seddon

Johanna M Seddon

Publications by authors named "Johanna M Seddon"

Are you Johanna M Seddon?   Register this Author

100Publications

1919Reads

41Profile Views

Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High-Risk Individuals.

Am J Ophthalmol 2019 Feb 31;198:223-261. Epub 2018 Oct 31.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469720PMC
February 2019

Progress in Automated Deep Learning for Macular Degeneration.

JAMA Ophthalmol 2018 Dec;136(12):1366-1367

Department of Ophthalmology & Visual Sciences, University of Massachusetts Medical School, Worcester.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2018.4108DOI Listing
December 2018

Macular Degeneration Epidemiology: Nature-Nurture, Lifestyle Factors, Genetic Risk, and Gene-Environment Interactions - The Weisenfeld Award Lecture.

Authors:
Johanna M Seddon

Invest Ophthalmol Vis Sci 2017 12;58(14):6513-6528

Ophthalmic Epidemiology and Genetics Service, Tufts Medical Center, Boston, Massachusetts, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.17-23544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749242PMC
December 2017

Rare Genetic Variants in Age-Related Macular Degeneration.

JAMA Ophthalmol 2017 10;135(10):1045-1046

Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2017.3203DOI Listing
October 2017

Vitamin D and Age-Related Macular Degeneration.

Nutrients 2017 Oct 13;9(10). Epub 2017 Oct 13.

Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu9101120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691736PMC
October 2017

Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration.

Invest Ophthalmol Vis Sci 2017 09;58(11):4569-4578

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, Massachusetts, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.17-21673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595226PMC
September 2017

Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration.

Invest Ophthalmol Vis Sci 2017 07;58(9):3519-3529

Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts, United States 2Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, Massachusetts, United States 5Sackler School of Graduate Biomedical Sciences and Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, United States.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
Publisher Site
http://dx.doi.org/10.1167/iovs.17-21696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512971PMC
July 2017

Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis.

Br J Ophthalmol 2016 Dec 28;100(12):1731-1737. Epub 2016 Jul 28.

Channing Division of Network Medicine, Harvard Medical School, Harvard University, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2016-3086
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2016-308624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570490PMC
December 2016

Idiopathic preretinal glia in aging and age-related macular degeneration.

Exp Eye Res 2016 09 26;150:44-61. Epub 2015 Jul 26.

Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins Hospital, 400 N. Broadway, Baltimore, MD, 21287, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2015.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728061PMC
September 2016

Contribution of the Nurses' Health Study to the Epidemiology of Cataract, Age-Related Macular Degeneration, and Glaucoma.

Am J Public Health 2016 Sep 26;106(9):1684-9. Epub 2016 Jul 26.

Jae H. Kang is with the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Juan Wu is with the Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston. Eunyoung Cho is with the Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, RI. Soshiro Ogata is with the Department of Health Promotion Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Paul Jacques, Allen Taylor, and Chung-Jung Chiu are with the Laboratory for Nutrition and Vision Research, Jean Mayer USDA Human Nutrition Center on Aging, Tufts University, Boston. Janey L. Wiggs and Louis R. Pasquale are with the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School. Johanna M. Seddon is with the Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Tufts University School of Medicine. Susan E. Hankinson is with the Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst. Debra A. Schaumberg is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2105/AJPH.2016.303317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981799PMC
September 2016

Increased choroidal mast cells and their degranulation in age-related macular degeneration.

Br J Ophthalmol 2016 May 1;100(5):720-6. Epub 2016 Mar 1.

Department of Ophthalmology, Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjophthalmol-2015-308290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913697PMC
May 2016

Predictors of Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment of Age-Related Macular Degeneration.

Am J Ophthalmol 2016 Mar 15;163:154-166.e8. Epub 2015 Dec 15.

New England Eye Center, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2015.11.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609150PMC
March 2016

Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study.

Am J Clin Nutr 2015 Nov 21;102(5):1196-206. Epub 2015 Oct 21.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3945/ajcn.115.111047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625588PMC
November 2015

Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels.

Hum Mol Genet 2015 Jul 18;24(13):3861-70. Epub 2015 Mar 18.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA, USA, Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA and Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddv091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459386PMC
July 2015

Phenotypic Characterization of Complement Factor H R1210C Rare Genetic Variant in Age-Related Macular Degeneration.

JAMA Ophthalmol 2015 Jul;133(7):785-91

New England Eye Center, Tufts University School of Medicine, Boston, Massachusetts2Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2015.0814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516461PMC
July 2015

Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates.

Invest Ophthalmol Vis Sci 2015 Apr;56(4):2192-202

Channing Division of Network Medicine, Harvard Medical School, Harvard University, Boston, Massachusetts, United States.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
Publisher Site
http://dx.doi.org/10.1167/iovs.14-15841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405097PMC
April 2015

Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.

PLoS One 2014 31;9(1):e87047. Epub 2014 Jan 31.

Channing Laboratory, Brigham and Women's Hospital and Harvard School of Public Health, Harvard University, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087047PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909074PMC
October 2014

Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.

Hum Mol Genet 2014 Oct 20;23(19):5283-93. Epub 2014 May 20.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA, USA Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA Sackler School of Graduate Medical Sciences, Tufts University, Boston, MA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddu226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159152PMC
October 2014

Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.

J Clin Oncol 2014 Oct 2;32(29):3284-90. Epub 2014 Sep 2.

Jeannette R. Wong, Lindsay M. Morton, Margaret A. Tucker, Joshua N. Sampson, and Ruth A. Kleinerman, National Cancer Institute, Bethesda, MD; David H. Abramson, Memorial Sloan-Kettering Cancer Center, New York, NY; and Johanna M. Seddon, Tufts-New England Medical Center, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2013.54.7844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178525PMC
October 2014

Nature and nurture- genes and environment- predict onset and progression of macular degeneration.

Prog Retin Eye Res 2014 May 27;40:1-15. Epub 2013 Dec 27.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA, USA; Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA; Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.preteyeres.2013.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446565PMC
May 2014

Genetic and environmental underpinnings to age-related ocular diseases.

Authors:
Johanna M Seddon

Invest Ophthalmol Vis Sci 2013 Dec 13;54(14):ORSF28-30. Epub 2013 Dec 13.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.13-13234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864375PMC
December 2013

Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration.

Nat Genet 2013 Nov 15;45(11):1366-70. Epub 2013 Sep 15.

1] Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA. [2] Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts, USA. [3] Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902040PMC
November 2013

Regular aspirin use and risk of age-related macular degeneration.

Am J Ophthalmol 2013 Aug;156(2):213-217.e2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2013.04.023DOI Listing
August 2013

Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy.

Ophthalmology 2013 May 5;120(5):1020-8. Epub 2013 Mar 5.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2012.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758110PMC
May 2013

Validation of a prediction algorithm for progression to advanced macular degeneration subtypes.

JAMA Ophthalmol 2013 Apr;131(4):448-55

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2013.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547827PMC
April 2013

Seven new loci associated with age-related macular degeneration.

Authors:
Lars G Fritsche Wei Chen Matthew Schu Brian L Yaspan Yi Yu Gudmar Thorleifsson Donald J Zack Satoshi Arakawa Valentina Cipriani Stephan Ripke Robert P Igo Gabriëlle H S Buitendijk Xueling Sim Daniel E Weeks Robyn H Guymer Joanna E Merriam Peter J Francis Gregory Hannum Anita Agarwal Ana Maria Armbrecht Isabelle Audo Tin Aung Gaetano R Barile Mustapha Benchaboune Alan C Bird Paul N Bishop Kari E Branham Matthew Brooks Alexander J Brucker William H Cade Melinda S Cain Peter A Campochiaro Chi-Chao Chan Ching-Yu Cheng Emily Y Chew Kimberly A Chin Itay Chowers David G Clayton Radu Cojocaru Yvette P Conley Belinda K Cornes Mark J Daly Baljean Dhillon Albert O Edwards Evangelos Evangelou Jesen Fagerness Henry A Ferreyra James S Friedman Asbjorg Geirsdottir Ronnie J George Christian Gieger Neel Gupta Stephanie A Hagstrom Simon P Harding Christos Haritoglou John R Heckenlively Frank G Holz Guy Hughes John P A Ioannidis Tatsuro Ishibashi Peronne Joseph Gyungah Jun Yoichiro Kamatani Nicholas Katsanis Claudia N Keilhauer Jane C Khan Ivana K Kim Yutaka Kiyohara Barbara E K Klein Ronald Klein Jaclyn L Kovach Igor Kozak Clara J Lee Kristine E Lee Peter Lichtner Andrew J Lotery Thomas Meitinger Paul Mitchell Saddek Mohand-Saïd Anthony T Moore Denise J Morgan Margaux A Morrison Chelsea E Myers Adam C Naj Yusuke Nakamura Yukinori Okada Anton Orlin M Carolina Ortube Mohammad I Othman Chris Pappas Kyu Hyung Park Gayle J T Pauer Neal S Peachey Olivier Poch Rinki Ratna Priya Robyn Reynolds Andrea J Richardson Raymond Ripp Guenther Rudolph Euijung Ryu José-Alain Sahel Debra A Schaumberg Hendrik P N Scholl Stephen G Schwartz William K Scott Humma Shahid Haraldur Sigurdsson Giuliana Silvestri Theru A Sivakumaran R Theodore Smith Lucia Sobrin Eric H Souied Dwight E Stambolian Hreinn Stefansson Gwen M Sturgill-Short Atsushi Takahashi Nirubol Tosakulwong Barbara J Truitt Evangelia E Tsironi André G Uitterlinden Cornelia M van Duijn Lingam Vijaya Johannes R Vingerling Eranga N Vithana Andrew R Webster H-Erich Wichmann Thomas W Winkler Tien Y Wong Alan F Wright Diana Zelenika Ming Zhang Ling Zhao Kang Zhang Michael L Klein Gregory S Hageman G Mark Lathrop Kari Stefansson Rando Allikmets Paul N Baird Michael B Gorin Jie Jin Wang Caroline C W Klaver Johanna M Seddon Margaret A Pericak-Vance Sudha K Iyengar John R W Yates Anand Swaroop Bernhard H F Weber Michiaki Kubo Margaret M Deangelis Thierry Léveillard Unnur Thorsteinsdottir Jonathan L Haines Lindsay A Farrer Iris M Heid Gonçalo R Abecasis

Nat Genet 2013 Apr 3;45(4):433-9, 439e1-2. Epub 2013 Mar 3.

Institute of Human Genetics, University of Regensburg, Regensburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739472PMC
April 2013

Correction of phenotype misclassification based on high-discrimination genetic predictive risk models.

Epidemiology 2012 Nov;23(6):902-9

Department of Medicine, Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/EDE.0b013e31826c3129DOI Listing
November 2012

To Correct or Not to Correct-and How.

Epidemiology 2012 Nov;23(6):912-3

Departments of Medicine and Health Research and Policy, Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/EDE.0b013e31826cc1b3DOI Listing
November 2012

Genetic factors for choroidal neovascularization associated with high myopia.

Invest Ophthalmol Vis Sci 2012 Jul 27;53(8):5004-9. Epub 2012 Jul 27.

Faculté de Médecine Henri Mondor, Department of Ophthalmology, APHP-Assistance Publique Hôpitaux Paris, Groupe Hospitalier Albert Chenevier-Henri Mondor, University Paris Est, Creteil, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.12-9538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410690PMC
July 2012

Age-related macular degeneration.

Lancet 2012 May;379(9827):1728-38

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(12)60282-7DOI Listing
May 2012

Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models.

Invest Ophthalmol Vis Sci 2012 Mar 21;53(3):1548-56. Epub 2012 Mar 21.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.11-8657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339916PMC
March 2012

Increased risk of secondary uterine leiomyosarcoma in hereditary retinoblastoma.

Gynecol Oncol 2012 Feb 23;124(2):254-9. Epub 2011 Oct 23.

Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S009082581100861
Publisher Site
http://dx.doi.org/10.1016/j.ygyno.2011.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264733PMC
February 2012

Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study.

Am J Ophthalmol 2011 Dec 9;152(6):1005-1013.e1. Epub 2011 Sep 9.

Department of Genetics & Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2011.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446967PMC
December 2011

Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Ophthalmology 2011 Nov 29;118(11):2203-11. Epub 2011 Sep 29.

Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, New England Eye Center, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2011.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097877PMC
November 2011

Automated discovery and quantification of image-based complex phenotypes: a twin study of drusen phenotypes in age-related macular degeneration.

Invest Ophthalmol Vis Sci 2011 Nov 25;52(12):9195-206. Epub 2011 Nov 25.

Institute for Vision Research, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.10-6793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302481PMC
November 2011

Kidney function, albuminuria and age-related macular degeneration in NHANES III.

Nephrol Dial Transplant 2011 Oct 21;26(10):3159-65. Epub 2011 Feb 21.

Division of Nephrology, Department of Medicine, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ndt/gfr022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247860PMC
October 2011

Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.

Invest Ophthalmol Vis Sci 2011 Jun 28;52(7):4663-70. Epub 2011 Jun 28.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.10-7070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175969PMC
June 2011

ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration.

Am J Ophthalmol 2011 Feb 3;151(2):345-52.e3. Epub 2010 Dec 3.

Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2010.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763907PMC
February 2011

Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration.

Mol Vis 2010 Nov 17;16:2412-24. Epub 2010 Nov 17.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, and Channing Laboratory, Brigham and Women's Hospital, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994762PMC
November 2010

Genetic epidemiology: successes and challenges of genome-wide association studies using the example of age-related macular degeneration.

Am J Ophthalmol 2010 Oct;150(4):450-452.e2

Department of Genetics and Genomic Sciences, Mount SinaiSchool of Medicine, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2010.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711490PMC
October 2010

Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration.

Ophthalmology 2010 Oct;117(10):1989-95

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2010.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081670PMC
October 2010

C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration.

Ophthalmology 2010 Aug 26;117(8):1560-6. Epub 2010 Mar 26.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2009.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711558PMC
August 2010

Cystoid macular edema without macular thickening: a retrospective optical coherence tomographic study.

Retina 2010 Jun;30(6):917-23

New England Eye Center, Tufts University School of Medicine, Boston, Massachusetts 02116, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IAE.0b013e3181cbd9e5DOI Listing
June 2010

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Proc Natl Acad Sci U S A 2010 Apr 12;107(16):7401-6. Epub 2010 Apr 12.

Center for Statistical Genetics, Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0912702107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867722PMC
April 2010

Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes.

Invest Ophthalmol Vis Sci 2009 Dec 6;50(12):5818-27. Epub 2009 Aug 6.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.09-3928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826794PMC
December 2009

Risk of cataract extraction among adult retinoblastoma survivors.

Arch Ophthalmol 2009 Nov;127(11):1500-4

Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7238, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/archophthalmol.2009.271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818500PMC
November 2009

Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables.

Invest Ophthalmol Vis Sci 2009 May 30;50(5):2044-53. Epub 2008 Dec 30.

Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/data/Journals/IOVS/932959/z7g00
Web Search
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
Publisher Site
http://dx.doi.org/10.1167/iovs.08-3064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772781PMC
May 2009

Geographic atrophy in age-related macular degeneration and TLR3.

N Engl J Med 2009 May;360(21):2254-5; author reply 2255-6

View Article

Download full-text PDF

Source
May 2009

Cause-specific mortality in long-term survivors of retinoblastoma.

J Natl Cancer Inst 2009 Apr 7;101(8):581-91. Epub 2009 Apr 7.

Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health/DHHS, 6120 Executive Blvd., Rockville, MD 20892-7238, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djp046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669101PMC
April 2009

Peripheral retinal drusen and reticular pigment: association with CFHY402H and CFHrs1410996 genotypes in family and twin studies.

Invest Ophthalmol Vis Sci 2009 Feb 20;50(2):586-91. Epub 2008 Oct 20.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts University School of Medicine and Tufts Medical Center, New England Eye Center, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
Publisher Site
http://dx.doi.org/10.1167/iovs.08-2514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498874PMC
February 2009

Variation near complement factor I is associated with risk of advanced AMD.

Eur J Hum Genet 2009 Jan 6;17(1):100-4. Epub 2008 Aug 6.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2008.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2985963PMC
January 2009

Cancer screening practices of adult survivors of retinoblastoma at risk of second cancers.

Cancer 2008 Jul;113(2):434-41

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.23564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012415PMC
July 2008

CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration.

Ophthalmology 2008 Jun;115(6):1019-25

Macular Degeneration Center, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016164200800103
Publisher Site
http://dx.doi.org/10.1016/j.ophtha.2008.01.036DOI Listing
June 2008

Review of genetics in age related macular degeneration.

Semin Ophthalmol 2007 Oct-Dec;22(4):229-40

Massachusetts Eye and Ear Infirmary and the Department of Ophthalmology, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/08820530701745140DOI Listing
February 2008

Variation in complement factor 3 is associated with risk of age-related macular degeneration.

Nat Genet 2007 Oct 2;39(10):1200-1. Epub 2007 Sep 2.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ng2131
Publisher Site
http://dx.doi.org/10.1038/ng2131DOI Listing
October 2007

The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration.

Hum Hered 2007 7;63(3-4):212-8. Epub 2007 Mar 7.

Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/100046
Publisher Site
http://dx.doi.org/10.1159/000100046DOI Listing
June 2007

Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration.

JAMA 2007 Apr;297(16):1793-800

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts-New England Medical Center, Boston, MA 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.297.16.1793DOI Listing
April 2007

Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma.

J Natl Cancer Inst 2007 Jan;99(1):24-31

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPS 7044, 6120 Executive Blvd., Rockville, MD 20852, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djk002DOI Listing
January 2007

Multivitamin-multimineral supplements and eye disease: age-related macular degeneration and cataract.

Authors:
Johanna M Seddon

Am J Clin Nutr 2007 Jan;85(1):304S-307S

Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ajcn/85.1.304SDOI Listing
January 2007

CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration.

Hum Hered 2006 30;61(3):157-65. Epub 2006 Jun 30.

Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000094141DOI Listing
October 2006

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration.

Nat Genet 2006 Sep 27;38(9):1055-9. Epub 2006 Aug 27.

Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge St., Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng1873DOI Listing
September 2006

The genetics of age-related macular degeneration: a review of progress to date.

Surv Ophthalmol 2006 Jul-Aug;51(4):316-63

Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, 02114, USA.

View Article

Download full-text PDF

Source
http://www.krepublishers.com/02-Journals/IJHG/IJHG-08-0-000-
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S003962570600091
Publisher Site
http://dx.doi.org/10.1016/j.survophthal.2006.05.001DOI Listing
August 2006

Tobacco use in adult long-term survivors of retinoblastoma.

Cancer Epidemiol Biomarkers Prev 2006 Aug;15(8):1464-8

Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS 7044, 6120 Executive Boulevard, Rockville, MD 20852, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1055-9965.EPI-05-0783DOI Listing
August 2006

Hormone therapy and age-related macular degeneration: the Women's Health Initiative Sight Exam Study.

Arch Ophthalmol 2006 Jul;124(7):988-92

Department of Epidemiology, University of Michigan, 611 Church Street, Ann Arbor, MI 48104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/archopht.124.7.988DOI Listing
July 2006

Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration.

Arch Ophthalmol 2006 Jul;124(7):995-1001

Massachusetts Eye and Ear Infirmary and Channing Laboratory, Harvard Medical School, 243 Charles Street, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/archopht.124.7.995DOI Listing
July 2006

C-reactive protein and homocysteine are associated with dietary and behavioral risk factors for age-related macular degeneration.

Nutrition 2006 Apr;22(4):441-3

Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nut.2005.12.004DOI Listing
April 2006

Evaluation of the clinical age-related maculopathy staging system.

Ophthalmology 2006 Feb;113(2):260-6

Epidemiology Unit, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2005.11.001DOI Listing
February 2006

Evaluation of plasma homocysteine and risk of age-related macular degeneration.

Am J Ophthalmol 2006 Jan;141(1):201-3

Epidemiology Unit, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2005.07.059DOI Listing
January 2006

Choroidal and cutaneous melanoma: distinctly different cousins.

Ophthalmic Epidemiol 2005 Aug;12(4):221-2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09286580500186389DOI Listing
August 2005

Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers.

Arch Ophthalmol 2005 Jun;123(6):774-82

Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/archopht.123.6.774DOI Listing
June 2005

A discordant sib-pair linkage analysis of age-related macular degeneration.

Ophthalmic Genet 2005 Jun;26(2):61-7

Psychiatric & Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13816810490967944DOI Listing
June 2005

Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up.

J Clin Oncol 2005 Apr;23(10):2272-9

Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852-7362, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2005.05.054DOI Listing
April 2005