Publications by authors named "Johann E Gudjonsson"

100Publications

Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin.

JCI Insight 2020 Oct 15;5(20). Epub 2020 Oct 15.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1172/jci.insight.142067DOI Listing
October 2020

Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies.

Immunity 2020 Oct;53(4):878-894.e7

Institute for Medical Engineering & Science (IMES), MIT, Cambridge, Massachusetts, USA; Department of Immunology, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA; Harvard Stem Cell Institute, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562821PMC
October 2020

"Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis.

Cell Mol Immunol 2020 Aug 19. Epub 2020 Aug 19.

Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41423-020-0519-3DOI Listing
August 2020

Mechanisms of skin autoimmunity: Cellular and soluble immune components of the skin.

J Allergy Clin Immunol 2020 Jul;146(1):8-16

Division of Dermatology and Venereology, Department of Medicine Solna, and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Unit of Dermatology, Karolinska University Hospital, Department of Dermatology and Venereology, Stockholm, Sweden; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.05.009DOI Listing
July 2020

Meeting Report: 68 Montagna Symposium on the Biology of Skin "Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology".

J Invest Dermatol 2020 Jun 27. Epub 2020 Jun 27.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Dermatology Service, Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2020.06.010DOI Listing
June 2020

Cutaneous Adverse Events in Newly Approved FDA Non-cancer Drugs: A Systematic Review.

Drugs R D 2020 Sep;20(3):171-187

Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, 2012 Kenny Road, Rm 232, Columbus, OH, 43212, USA.

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http://dx.doi.org/10.1007/s40268-020-00311-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419407PMC
September 2020

Epigenetics of Psoriasis.

Adv Exp Med Biol 2020 ;1253:209-221

Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/978-981-15-3449-2_8DOI Listing
July 2020

Recent genetic advances in innate immunity of psoriatic arthritis.

Clin Immunol 2020 05 2;214:108405. Epub 2020 Apr 2.

Department of Dermatology, University of Michigan, Ann Arbor 48109, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2020.108405DOI Listing
May 2020

Targeted Treatment for Erythrodermic Psoriasis: Rationale and Recent Advances.

Drugs 2020 Apr;80(6):525-534

Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1007/s40265-020-01283-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167352PMC
April 2020

Treatment of cutaneous lupus erythematosus: current approaches and future strategies.

Curr Opin Rheumatol 2020 05;32(3):208-214

Division of Rheumatology, Department of Internal Medicine.

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http://dx.doi.org/10.1097/BOR.0000000000000704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357847PMC
May 2020

Circadian control of interferon-sensitive gene expression in murine skin.

Proc Natl Acad Sci U S A 2020 03 4;117(11):5761-5771. Epub 2020 Mar 4.

Department of Biological Chemistry, University of California, Irvine, CA 92697;

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http://dx.doi.org/10.1073/pnas.1915773117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084068PMC
March 2020

Biologics in the treatment of skin and rheumatologic diseases.

J Allergy Clin Immunol 2020 Apr 27;145(4):1138-1141. Epub 2020 Feb 27.

Department of Dermatology, University of Michigan, Ann Arbor, Mich. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.02.017DOI Listing
April 2020

Staphylococcus aureus Colonization Is Increased on Lupus Skin Lesions and Is Promoted by IFN-Mediated Barrier Disruption.

J Invest Dermatol 2020 May 23;140(5):1066-1074.e4. Epub 2019 Dec 23.

Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183889PMC
May 2020

IL-17A Softens the Skin: Antifibrotic Properties of IL-17A in Systemic Sclerosis.

J Invest Dermatol 2020 01;140(1):13-14

Department of Dermatology, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.07.678DOI Listing
January 2020

Psoriasis: Past, Present, and Future.

J Invest Dermatol 2019 11;139(11):e133-e142

Department of Dermatology, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1016/j.jid.2019.08.437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989032PMC
November 2019

SIRT3 Regulates Macrophage-Mediated Inflammation in Diabetic Wound Repair.

J Invest Dermatol 2019 12 15;139(12):2528-2537.e2. Epub 2019 Jun 15.

Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185380PMC
December 2019

Interleukin-17 receptor D: An orphan receptor finds a home in the skin.

Sci Immunol 2019 06 7;4(36). Epub 2019 Jun 7.

Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1126/sciimmunol.aax0687DOI Listing
June 2019

Overriding the Immune System's Sweet Tooth: Fatty Acids Rile Up Innate Immunity.

Cell 2019 05;177(5):1088-1090

Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.04.033DOI Listing
May 2019

Making New Connections-Chromosome Conformation Capture for Identification of Disease-Associated Target Genes.

J Invest Dermatol 2019 03;139(3):514-517

Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.11.026DOI Listing
March 2019

Adalimumab in Psoriasis: How Much Is Enough?

J Invest Dermatol 2019 01;139(1):19-22

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357200PMC
January 2019

The influence of interferon on healthy and diseased skin.

Cytokine 2020 Aug 6;132:154605. Epub 2018 Dec 6.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10434666183044
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http://dx.doi.org/10.1016/j.cyto.2018.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551332PMC
August 2020

Human and Murine Evidence for Mechanisms Driving Autoimmune Photosensitivity.

Front Immunol 2018 23;9:2430. Epub 2018 Oct 23.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fimmu.2018.02430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205973PMC
September 2019

Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach.

J Invest Dermatol 2019 03 17;139(3):683-691. Epub 2018 Oct 17.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan USA; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387843PMC
March 2019

Research Techniques Made Simple: Murine Models of Human Psoriasis.

J Invest Dermatol 2018 01;138(1):e1-e8

Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902858PMC
January 2018

Unsuspected lymphomatoid granulomatosis in a patient with antisynthetase syndrome.

Cutis 2017 Oct;100(4):E22-E26

Department of Dermatology, Department of Pathology, University of Michigan, Ann Arbor, USA.

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October 2017

Psoriasis: a mixed autoimmune and autoinflammatory disease.

Curr Opin Immunol 2017 Dec 22;49:1-8. Epub 2017 Jul 22.

Department of Dermatology, University of Michigan, 1910 Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2017.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705427PMC
December 2017

A vestigial pathway for sex differences in immune regulation.

Cell Mol Immunol 2017 07 22;14(7):578-580. Epub 2017 May 22.

Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1038/cmi.2017.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520416PMC
July 2017

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice.

J Clin Invest 2017 Jun 2;127(6):2339-2352. Epub 2017 May 2.

Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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https://www.jci.org/articles/view/92217
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http://dx.doi.org/10.1172/JCI92217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451229PMC
June 2017

GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.

PLoS Genet 2017 04 26;13(4):e1006745. Epub 2017 Apr 26.

Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425218PMC
April 2017

The Molecular Revolution in Cutaneous Biology: The Era of Global Transcriptional Analysis.

J Invest Dermatol 2017 05;137(5):e87-e91

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.02.817DOI Listing
May 2017

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis.

J Allergy Clin Immunol 2017 Jul 31;140(1):109-120. Epub 2016 Dec 31.

Department of Dermatology, University of Michigan, Ann Arbor, Mich.

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http://dx.doi.org/10.1016/j.jaci.2016.08.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494022PMC
July 2017

Induction of Alternative Proinflammatory Cytokines Accounts for Sustained Psoriasiform Skin Inflammation in IL-17C+IL-6KO Mice.

J Invest Dermatol 2017 03 27;137(3):696-705. Epub 2016 Oct 27.

Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA; Murdough Family Center for Psoriasis, Cleveland, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326585PMC
March 2017

The Snowballing Literature on Imiquimod-Induced Skin Inflammation in Mice: A Critical Appraisal.

J Invest Dermatol 2017 03 9;137(3):546-549. Epub 2016 Dec 9.

Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X163260
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http://dx.doi.org/10.1016/j.jid.2016.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326590PMC
March 2017

Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop.

J Invest Dermatol 2017 01 16;137(1):115-122. Epub 2016 Sep 16.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183476PMC
January 2017

Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

J Invest Dermatol 2016 09 14;136(9):1792-1800. Epub 2016 Jun 14.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.05.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112032PMC
September 2016

Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature.

J Invest Dermatol 2016 09 17;136(9):1820-1830. Epub 2016 May 17.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/j.jid.2016.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234565PMC
September 2016

Ongoing Pleuritic Chest Pain and a Guinea Pig: Missed Pulmonary Embolism and Majocchi's Granuloma.

Am J Med 2016 Sep 18;129(9):e165-7. Epub 2016 Apr 18.

Department of Dermatology, University of Michigan Medical School, Ann Arbor.

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http://dx.doi.org/10.1016/j.amjmed.2016.03.029DOI Listing
September 2016

CYR61/CCN1: A Novel Mediator of Epidermal Hyperplasia and Inflammation in Psoriasis?

J Invest Dermatol 2015 Nov;135(11):2562-2564

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641044PMC
November 2015

In Reply.

JAMA Dermatol 2015 Oct;151(10):1144

XBiotech USA Inc, Austin, Texas.

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http://dx.doi.org/10.1001/jamadermatol.2015.1683DOI Listing
October 2015

Psoriasis and the MAITing game: a role for IL-17A+ invariant TCR CD8+ T cells in psoriasis?

J Invest Dermatol 2014 Dec;134(12):2864-2866

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X153656
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http://dx.doi.org/10.1038/jid.2014.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228793PMC
December 2014