Publications by authors named "Johan P de Winter"

58Publications

Molecular diagnosis of Fanconi anemia with next-generation sequencing in a case with subtle signs and a negative chromosomal breakage test.

Turk J Pediatr 2015 May-Jun;57(3):282-5

Division of Hematology, Department of Pediatrics, Gazi University Faculty of Medicine, Ankara, Turkey.

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August 2016

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.

Nat Commun 2015 Oct 1;6:8399. Epub 2015 Oct 1.

Department of Clinical Genetics, section Oncogenetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms9399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600715PMC
October 2015

DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity.

DNA Repair (Amst) 2015 Feb 24;26:54-64. Epub 2014 Dec 24.

Department of Clinical Genetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dnarep.2014.12.003DOI Listing
February 2015

Coregulation of FANCA and BRCA1 in human cells.

Springerplus 2014 28;3:381. Epub 2014 Jul 28.

Department of Clinical Genetics, Section Oncogenetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/2193-1801-3-381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143540PMC
August 2014

The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks.

Mol Cell 2013 Nov 24;52(3):434-46. Epub 2013 Oct 24.

Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.molcel.2013.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880019PMC
November 2013

Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models.

Dis Model Mech 2013 Jan;6(1):40-7

Division of Biological Stress Response, Netherlands Cancer Institute, Plesmanlaan 121, NL-1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1242/dmm.009795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529337PMC
January 2013

Whole exome sequencing reveals uncommon mutations in the recently identified Fanconi anemia gene SLX4/FANCP.

Hum Mutat 2013 Jan 16;34(1):93-6. Epub 2012 Oct 16.

Department of Human Genetics, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1002/humu.22221DOI Listing
January 2013

Diagnosis of Fanconi Anemia: Mutation Analysis by Multiplex Ligation-Dependent Probe Amplification and PCR-Based Sanger Sequencing.

Anemia 2012 21;2012:603253. Epub 2012 Jun 21.

Department of Clinical Genetics, VU University Medical Center, Van der Boechorsttraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1155/2012/603253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388349PMC
August 2012

Diagnosis of fanconi anemia: mutation analysis by next-generation sequencing.

Anemia 2012 3;2012:132856. Epub 2012 Jun 3.

Department of Clinical Genetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1155/2012/132856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374947PMC
August 2012

Diagnosis of fanconi anemia: chromosomal breakage analysis.

Anemia 2012 24;2012:238731. Epub 2012 May 24.

Department of Clinical Genetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1155/2012/238731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368163PMC
August 2012

A role for ATM in hereditary pancreatic cancer.

Cancer Discov 2012 Jan;2(1):14-5

Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-11-0318DOI Listing
January 2012

Biochemical characterization of Warsaw breakage syndrome helicase.

J Biol Chem 2012 Jan 18;287(2):1007-21. Epub 2011 Nov 18.

Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.276022
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http://dx.doi.org/10.1074/jbc.M111.276022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256869PMC
January 2012

Fancf-deficient mice are prone to develop ovarian tumours.

J Pathol 2012 Jan 14;226(1):28-39. Epub 2011 Nov 14.

Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.2992DOI Listing
January 2012

Diagnostic Overlap between Fanconi Anemia and the Cohesinopathies: Roberts Syndrome and Warsaw Breakage Syndrome.

Anemia 2010 18;2010:565268. Epub 2010 Jul 18.

Department of Clinical Genetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1155/2010/565268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065841PMC
July 2011

Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication.

Mol Cell 2009 Sep;35(5):716-23

Department of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.06.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758766PMC
September 2009

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

Hum Mol Genet 2009 Sep 26;18(18):3484-95. Epub 2009 Jun 26.

Division of Molecular Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddp297DOI Listing
September 2009

The genetic and molecular basis of Fanconi anemia.

Mutat Res 2009 Jul 14;668(1-2):11-9. Epub 2008 Nov 14.

Department of Clinical Genetics, Section Oncogenetics, VU University Medical Center, Van der Boechorststraat 7, Amsterdam 1081 BT, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00275107080028
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http://dx.doi.org/10.1016/j.mrfmmm.2008.11.004DOI Listing
July 2009

Genetic subtyping of Fanconi anemia by comprehensive mutation screening.

Hum Mutat 2008 Jan;29(1):159-66

Department of Clinical Genetics, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/humu.20625DOI Listing
January 2008

Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer.

Breast Cancer Res Treat 2008 Jan 27;107(1):41-7. Epub 2007 Feb 27.

Department of Pathology, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s10549-007-9534-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096638PMC
January 2008

Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

Nat Genet 2007 Feb 31;39(2):159-61. Epub 2006 Dec 31.

Dana-Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ng1942DOI Listing
February 2007

Evidence for subcomplexes in the Fanconi anemia pathway.

Blood 2006 Sep 23;108(6):2072-80. Epub 2006 May 23.

Department of Clinical Genetics and Human Genetics, Vrije Universiteit University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2005-11-00
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http://dx.doi.org/10.1182/blood-2005-11-008151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895538PMC
September 2006

The Fanconi anemia pathway of genomic maintenance.

Cell Oncol 2006 ;28(1-2):3-29

Division of Clinical Genetics and Human Genetics, VU Medical Center, van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617492PMC
http://dx.doi.org/10.1155/2006/974975DOI Listing
July 2006

The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC.

DNA Repair (Amst) 2006 May 28;5(5):556-65. Epub 2006 Feb 28.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dnarep.2006.01.005DOI Listing
May 2006

The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J.

Nat Genet 2005 Sep 21;37(9):934-5. Epub 2005 Aug 21.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng1625DOI Listing
September 2005

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

Nat Genet 2005 Sep 21;37(9):958-63. Epub 2005 Aug 21.

Division of Experimental Hematology, Cincinnati Children's Hospital Research Foundation and University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.

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http://www.nature.com/articles/ng1626
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http://dx.doi.org/10.1038/ng1626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704909PMC
September 2005

Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.

Hum Mol Genet 2005 May 24;14(10):1271-81. Epub 2005 Mar 24.

Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddi138DOI Listing
May 2005

FANCD2 expression in advanced non-small-cell lung cancer and response to platinum-based chemotherapy.

Clin Lung Cancer 2005 Jan;6(4):250-4

Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.3816/CLC.2005.n.005DOI Listing
January 2005

X-linked inheritance of Fanconi anemia complementation group B.

Nat Genet 2004 Nov 24;36(11):1219-24. Epub 2004 Oct 24.

Laboratory of Genetics, National Institute on Aging, National Institutes of Health, 333 Cassell Drive, TRIAD Center Room 3000, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1038/ng1458DOI Listing
November 2004

The Fanconi anemia gene product FANCF is a flexible adaptor protein.

J Biol Chem 2004 Sep 15;279(38):39421-30. Epub 2004 Jul 15.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M407034200DOI Listing
September 2004

Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA.

Cancer Gene Ther 2004 Aug;11(8):539-46

Department of Medical Oncology, Division of Gene Therapy, VU University Medical Center, Amsterdam, The Netherlands.

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http://www.nature.com/articles/7700734
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http://dx.doi.org/10.1038/sj.cgt.7700734DOI Listing
August 2004

Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways.

Hum Mol Genet 2004 Jun 28;13(12):1241-8. Epub 2004 Apr 28.

Division of Genetics and Development, Guy's, King's and St Thomas's School of Medicine, King's College London, UK.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddh135DOI Listing
June 2004

Multiple TPR motifs characterize the Fanconi anemia FANCG protein.

DNA Repair (Amst) 2004 Jan;3(1):77-84

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081 BT, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dnarep.2003.09.007DOI Listing
January 2004

Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes.

Blood 2004 Apr 20;103(7):2498-503. Epub 2003 Nov 20.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2003-08-2915DOI Listing
April 2004

Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia.

Br J Haematol 2003 Nov;123(3):469-71

Department of Medical and Molecular Genetics, Division of Genetics and Development Guy's, King's and St Thomas's School of Medicine, King's College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04640.xDOI Listing
November 2003

FANCD2 protein is expressed in proliferating cells of human tissues that are cancer-prone in Fanconi anaemia.

J Pathol 2003 Oct;201(2):198-203

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.1450DOI Listing
October 2003

A novel ubiquitin ligase is deficient in Fanconi anemia.

Nat Genet 2003 Oct 14;35(2):165-70. Epub 2003 Sep 14.

Laboratory of Genetics, National Institute on Aging, National Institutes of Health, 333 Cassell Drive, TRIAD Center Room 3000, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1038/ng1241DOI Listing
October 2003

Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2.

Cancer Res 2003 May;63(10):2688-94

Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo 160-8582, Japan.

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May 2003

Analysis of baseline and cisplatin-inducible gene expression in Fanconi anemia cells using oligonucleotide-based microarrays.

BMC Blood Disord 2002 Nov 26;2(1). Epub 2002 Nov 26.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Amsterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC138804PMC
http://dx.doi.org/10.1186/1471-2326-2-5DOI Listing
November 2002

Evolutionary clues to the molecular function of fanconi anemia genes.

Acta Haematol 2002 ;108(4):231-6

Department of Clinical Genetics and Human Genetics, Free University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000065659DOI Listing
January 2003