Johan Maertens

Johan Maertens

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Johan Maertens

Publications by authors named "Johan Maertens"

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Gliotoxin and bis(methylthio)gliotoxin are not reliable as biomarkers of invasive aspergillosis.

Mycoses 2019 Oct 12;62(10):945-948. Epub 2019 Aug 12.

Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/myc.12967DOI Listing
October 2019

Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system.

Med Mycol 2019 Oct 15. Epub 2019 Oct 15.

Weiden Clinic, Weiden; and University Medical Center, Würzburg, Germany.

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http://dx.doi.org/10.1093/mmy/myz103DOI Listing
October 2019

Using routine blood parameters to anticipate clinical outcomes in invasive aspergillosis.

Clin Microbiol Infect 2019 Oct 24. Epub 2019 Oct 24.

Division of Infectious Diseases, University Medicine Cluster, National University Health System, Singapore and Yong Loo Lin School of Medicine, National University of Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.cmi.2019.10.019DOI Listing
October 2019

Prevalence of voriconazole-resistant invasive aspergillosis and its impact on mortality in haematology patients.

J Antimicrob Chemother 2019 Sep;74(9):2759-2766

Laboratory of Clinical Bacteriology and Mycology, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dkz258DOI Listing
September 2019

Maribavir for Preemptive Treatment of Cytomegalovirus Reactivation.

N Engl J Med 2019 09;381(12):1136-1147

From the Hematology Department, University Hospitals Leuven, KU Leuven, Leuven (J.M.), and the Section of Hematology, Cliniques Universitaires Saint-Luc, Brussels (X.P.) - both in Belgium; the Hematology Department, Henri Mondor Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP) and University Paris-Est-Créteil, Créteil (C.C.), and AP-HP Hôpital Paul Brousse, Villejuif (F.S.) - all in France; the Medical University of Vienna, General Hospital, Vienna (P.J.); Shire, Wayne, PA (M.U., S.V.); Shire, Lexington, MA (J.W., A.W.); and the Department of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany (O.W.).

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http://dx.doi.org/10.1056/NEJMoa1714656DOI Listing
September 2019

Antifungal drugs: What brings the future?

Med Mycol 2019 Jun;57(Supplement_3):S328-S343

Pharmacy Department, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1093/mmy/myz012DOI Listing
June 2019

Fungal infections in solid organ transplantation: An update on diagnosis and treatment.

Transplant Rev (Orlando) 2019 04 13;33(2):77-86. Epub 2018 Dec 13.

KU Leuven, Laboratory of Nephrology, Herestraat 49, 3000 Leuven, Belgium; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.trre.2018.12.001DOI Listing
April 2019

Ibrutinib Regimens in Older Patients with Untreated CLL.

N Engl J Med 2019 04;380(17):1679-1681

Catholic University of Leuven, Leuven, Belgium

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http://dx.doi.org/10.1056/NEJMc1901284DOI Listing
April 2019

An introduction to current standards of CARE in invasive fungal disease.

J Antimicrob Chemother 2019 Mar;74(Supplement_2):ii2

Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dkz036DOI Listing
March 2019

Defining standards of CARE for invasive fungal diseases in adult haematology patients: antifungal prophylaxis versus treatment.

J Antimicrob Chemother 2019 Mar;74(Supplement_2):ii21-ii26

Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dkz040DOI Listing
March 2019

Standards of CARE: what is considered 'best practice' for the management of invasive fungal infections? A haematologist's and a mycologist's perspective.

J Antimicrob Chemother 2019 Mar;74(Supplement_2):ii3-ii8

Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dkz037DOI Listing
March 2019

Letermovir for prophylaxis of cytomegalovirus manifestations in adult allogeneic hematopoietic stem cell transplant recipients.

Future Microbiol 2019 02 15;14:175-184. Epub 2019 Jan 15.

Department of Hematology, University Hospitals Leuven, Leuven, Belgium.

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https://www.futuremedicine.com/doi/10.2217/fmb-2018-0250
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http://dx.doi.org/10.2217/fmb-2018-0250DOI Listing
February 2019

Pharmacokinetic drug evaluation of letermovir prophylaxis for cytomegalovirus in hematopoietic stem cell transplantation.

Expert Opin Drug Metab Toxicol 2018 Dec 4;14(12):1197-1207. Epub 2018 Dec 4.

c Department of Microbiology and Immunology , KU Leuven , Leuven , Belgium.

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https://www.tandfonline.com/doi/full/10.1080/17425255.2018.1
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http://dx.doi.org/10.1080/17425255.2018.1550485DOI Listing
December 2018

A Multimodal Imaging Approach Enables Assessment of Antifungal Treatment in a Mouse Model of Invasive Pulmonary Aspergillosis.

Antimicrob Agents Chemother 2018 07 26;62(7). Epub 2018 Jun 26.

Laboratory of Clinical Bacteriology and Mycology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1128/AAC.00240-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021662PMC
July 2018

Galactomannan, a Surrogate Marker for Outcome in Invasive Aspergillosis: Finally Coming of Age.

Front Microbiol 2018 4;9:661. Epub 2018 Apr 4.

Laboratory of Clinical Bacteriology and Mycology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3389/fmicb.2018.00661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893815PMC
April 2018

Letermovir Prophylaxis for Cytomegalovirus.

N Engl J Med 2018 03;378(10):965

Merck, Kenilworth, NJ

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http://dx.doi.org/10.1056/NEJMc1800572DOI Listing
March 2018

Increasing candidaemia incidence from 2004 to 2015 with a shift in epidemiology in patients preexposed to antifungals.

Mycoses 2018 Feb 15;61(2):127-133. Epub 2017 Nov 15.

Department of Microbiology and Immunology, Laboratory of Clinical Bacteriology and Mycology, University of Leuven, University Hospitals Leuven, Leuven, Belgium.

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http://doi.wiley.com/10.1111/myc.12714
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http://dx.doi.org/10.1111/myc.12714DOI Listing
February 2018

Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation.

N Engl J Med 2017 12 6;377(25):2433-2444. Epub 2017 Dec 6.

From the Dana-Farber Cancer Institute and Brigham and Women's Hospital (F.M.M.) and Tufts Medical Center and Tufts University School of Medicine (D.R.S.), Boston; Karolinska University Hospital and Karolinska Institutet, Stockholm (P.L.); University of Texas M.D. Anderson Cancer Center, Houston (R.F.C.); Universitaire Ziekenhuizen Leuven, Leuven, Belgium (J.M.); City of Hope National Medical Center, Duarte (S.S.D.), and Stanford University School of Medicine, Palo Alto (J.B.) - both in California; Hospital Universitario Puerta de Hierro-Majadahonda, Madrid (R.F.D.); Juravinski Hospital and Cancer Center, McMaster University, Hamilton, ON, Canada (S.H.); Universitätsklinikum Würzburg, Würzburg, Germany (A.J.U., H.E.); Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, Hiroshima (Y. Katayama), and Saitama Medical Center, Jichi Medical University, Saitama (Y. Kanda) - both in Japan; University of Chicago, Chicago (K.M.M.); Fred Hutchinson Cancer Research Center, Seattle (M.B.); Perelman School of Medicine at the University of Pennsylvania, Philadelphia (E.A.B.); and Merck, Kenilworth, NJ (M.J.D., V.L.T., H.W., Y.M., N.A.K., R.Y.L., C.B.).

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http://dx.doi.org/10.1056/NEJMoa1706640DOI Listing
December 2017

The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases.

Virulence 2017 08 7;8(6):673-684. Epub 2016 Nov 7.

a Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho , Braga , Portugal.

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http://dx.doi.org/10.1080/21505594.2016.1257458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626249PMC
August 2017

Current and future options for cytomegalovirus reactivation in hematopoietic cell transplantation patients.

Future Microbiol 2017 08 26;12:839-842. Epub 2017 Jul 26.

Freelance Medical Writer, London, UK.

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http://dx.doi.org/10.2217/fmb-2017-0095DOI Listing
August 2017

Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole.

Antimicrob Agents Chemother 2017 06 24;61(6). Epub 2017 May 24.

Antimicrobial Pharmacodynamics and Therapeutics, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

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http://aac.asm.org/lookup/doi/10.1128/AAC.00101-17
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http://dx.doi.org/10.1128/AAC.00101-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444187PMC
June 2017

Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response.

Clin Infect Dis 2017 Jun;64(11):1557-1563

Antimicrobial Pharmacodynamics and Therapeutics, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, United Kingdom.

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http://dx.doi.org/10.1093/cid/cix198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434340PMC
June 2017

Clinical considerations in the early treatment of invasive mould infections and disease.

J Antimicrob Chemother 2017 03;72(suppl_1):i29-i38

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http://dx.doi.org/10.1093/jac/dkx031DOI Listing
March 2017

Effect of the Direct Oral Anticoagulants Rivaroxaban and Apixaban on the Disposition of Calcineurin Inhibitors in Transplant Recipients.

Ther Drug Monit 2017 02;39(1):77-82

*Department of Microbiology and Immunology, KU Leuven-University of Leuven; Departments of †Nephrology and Renal Transplantation, ‡Pharmacy, §Pharmaceutical and Pharmacological Sciences, Clinical Pharmacology and Pharmacotherapy; ¶Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven-University of Leuven; Departments of ‖Hematology, **Cardiology, ††Respiratory diseases, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/FTD.0000000000000356DOI Listing
February 2017

High-Dose Chemotherapy for Adult-Type Ovarian Granulosa Cell Tumors: A Retrospective Study of the European Society for Blood and Marrow Transplantation.

Int J Gynecol Cancer 2017 02;27(2):248-251

*Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Italy; †Centre Leon Berard, Lyon; and ‡EBMT Paris Office, Paris, France; §Universitatsklinikum Frankfurt, Frankfurt, Germany; ∥Hopital Tenon, Paris, France; ¶University Hospital Gasthuisberg, Leuven, Belgium; and #Hematology Unit, Ravenna Hospital, Ravenna; and **Ospedale di Busto Arsizio, Varese, Italy.

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http://dx.doi.org/10.1097/IGC.0000000000000882DOI Listing
February 2017

The current management landscape: aspergillosis.

J Antimicrob Chemother 2016 11;71(suppl 2):ii23-ii29

Clinical Microbiology and Infectious Disease Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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http://dx.doi.org/10.1093/jac/dkw393DOI Listing
November 2016

Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2379-85. Epub 2016 May 12.

Department of Haematology, Acute Leukaemia and Stem Cell Transplantation Unit, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dkw155DOI Listing
September 2016

ECIL guidelines for the diagnosis of Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2386-96. Epub 2016 May 12.

Parasitology-Mycology Laboratory, Groupe Hospitalier Lariboisière Saint-Louis Fernand Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Diderot, Sorbonne Paris Cité, and Institut Pasteur, Unité de Mycologie Moléculaire, CNRS URA3012, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France.

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http://dx.doi.org/10.1093/jac/dkw156DOI Listing
September 2016

ECIL guidelines for preventing Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2397-404. Epub 2016 May 12.

Department of Haematology, Henri Mondor Teaching Hospital, Assistance Publique-Hôpitaux de Paris, and Université Paris-Est-Créteil, Créteil, France

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http://dx.doi.org/10.1093/jac/dkw157DOI Listing
September 2016

Posaconazole plasma exposure correlated to intestinal mucositis in allogeneic stem cell transplant patients.

Eur J Clin Pharmacol 2016 Aug 11;72(8):953-63. Epub 2016 Apr 11.

Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00228-016-2057-6DOI Listing
August 2016

Impact of Donor Epstein-Barr Virus Serostatus on the Incidence of Graft-Versus-Host Disease in Patients With Acute Leukemia After Hematopoietic Stem-Cell Transplantation: A Study From the Acute Leukemia and Infectious Diseases Working Parties of the European Society for Blood and Marrow Transplantation.

J Clin Oncol 2016 07 18;34(19):2212-20. Epub 2016 Apr 18.

Jan Styczynski, Collegium Medicum, Nicolaus Copernicus University Torun, Bydgoszcz; Lidia Gil, Medical University, Poznan, Poland; Gloria Tridello and Simone Cesaro, Azienda Ospedaliera Universitaria Integrata, Verona; Simona Iacobelli, Università di Roma "Tor Vergata", Roma, Italy; Per Ljungman, Karolinska University Hospital, Stockholm, Sweden; Jennifer Hoek, European Bone Marrow Transplantation Group Data Office; Hendrik Veelken, Leiden University Medical Center, Leiden; Jan Cornelissen, Erasmus MC-Daniel den Hoed Cancer Centre, Rotterdam; Eefke Petersen, University Medical Centre, Utrecht, the Netherlands; Katherine N. Ward, University College London, London, United Kingdom; Catherine Cordonnier, Hôpital Henri Mondor, Assistance Publique-Hopitaux de Paris and Paris-Est-Créteil University, Creteil; Gerard Socie, Hopital St Louis; Mohamad Mohty, Saint Antoine Hospital, Paris, Institut National de la Santé et de la Recherche Médicale UMR 938, Paris; Noel Milpied, Centre Hospitalier Universitaire Bordeaux, Pessac; Patrice Chevallier, Centre Hospitalier Universitaire, Nantes; Ibrahim Yakoub-Agha, Centre Hospitalier Régional Universitaire, Lille; Didier Blaise, Centre de Recherche en Cancerologie, Marseille; Mauricette Michallet, Centre Hospitalier Lyon Sud, Pierre-Benite; Etienne Daguindau, Hopital Jean Minjoz, Besancon, France; Hermann Einsele, University Hospital, Wurzburg; Nicolaus Kröger, University Hospital Eppendorf, Hamburg; Peter Dreger, University of Heidelberg, Heidelberg, Germany; Johan Maertens, University Hospital Gasthuisberg, Leuven, Belgium; Jakob Passweg, University Hospital, Basel, Switzerland; Hildegard Greinix, Medical University of Graz, Graz, Austria; Rafael F. Duarte, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain; and Arnon Nagler, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1200/JCO.2015.64.2405DOI Listing
July 2016

Longitudinal, in vivo assessment of invasive pulmonary aspergillosis in mice by computed tomography and magnetic resonance imaging.

Lab Invest 2016 06 28;96(6):692-704. Epub 2016 Mar 28.

Biomedical MRI Unit/ MoSAIC, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/labinvest.2016.45DOI Listing
June 2016

Cladophialophora bantiana osteomyelitis in a renal transplant patient.

Med Mycol Case Rep 2016 Jun 9;12:17-20. Epub 2016 Jul 9.

Department of Microbiology and Immunology, Laboratory of Nephrology, KU Leuven - University of Leuven, Belgium; Department of Nephrology, Dialysis and Renal Transplantation, University Hospitals Leuven, Herestraat 49, Leuven 3000, Belgium.

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http://dx.doi.org/10.1016/j.mmcr.2016.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995601PMC
June 2016

Pretreatment of Bronchoalveolar Lavage Fluid Samples with SLsolution Leads to False-Negative Aspergillus Galactomannan Levels.

J Clin Microbiol 2016 Apr 13;54(4):1171. Epub 2016 Jan 13.

Department of Microbiology and Immunology, KU Leuven-University of Leuven, Leuven, Belgium National Reference Center for Mycosis, Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium

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http://jcm.asm.org/content/early/2016/01/07/JCM.02968-15.ful
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http://jcm.asm.org/lookup/doi/10.1128/JCM.02968-15
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http://dx.doi.org/10.1128/JCM.02968-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809905PMC
April 2016

Plasmalyte: No Longer a Culprit in Causing False-Positive Galactomannan Test Results.

J Clin Microbiol 2016 Mar 30;54(3):795-7. Epub 2015 Dec 30.

Medical Intensive Care Unit, University Hospitals Leuven, Department of Microbiology and Immunology, Laboratory for Clinical Infectious and Inflammatory Diseases, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1128/JCM.02813-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767971PMC
March 2016