Johan M Kros

Johan M Kros

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Johan M Kros

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Elusive Neurotoxicity in T Cell-Boosting Anticancer Therapies.

Trends Immunol 2019 Apr 12;40(4):274-278. Epub 2019 Mar 12.

Department of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China; These authors contributed equally to this work. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.02.005DOI Listing
April 2019

CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions.

Angiogenesis 2019 02 10;22(1):75-93. Epub 2018 Aug 10.

Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9638-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510885PMC
February 2019

Flow cytometry shows added value in diagnosing lymphoma in brain biopsies.

Cytometry B Clin Cytom 2018 11 3;94(6):928-934. Epub 2018 Sep 3.

Department of Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/cyto.b.21641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585701PMC
November 2018

Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics.

Acta Neuropathol Commun 2018 11 23;6(1):126. Epub 2018 Nov 23.

Department of Pathology, Brain Tumor Center at Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s40478-018-0633-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251173PMC
November 2018

Breast cancer brain metastasis: molecular mechanisms and directions for treatment.

Neuro Oncol 2018 10;20(11):1439-1449

Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1093/neuonc/noy044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176797PMC
October 2018

Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.

Lancet Oncol 2018 09 13;19(9):1170-1179. Epub 2018 Aug 13.

The Brain and Spine Institute (ICM), Sorbonne Université, The National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Public Assistance-Paris Hospitals (AP-HP), Hôpital Pitié-Salpêtrière, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183036
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http://dx.doi.org/10.1016/S1470-2045(18)30362-0DOI Listing
September 2018

Approved CAR T cell therapies: ice bucket challenges on glaring safety risks and long-term impacts.

Drug Discov Today 2018 06 1;23(6):1175-1182. Epub 2018 Mar 1.

Department of Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1016/j.drudis.2018.02.012DOI Listing
June 2018

Potential Molecular Signatures Predictive of Lung Cancer Brain Metastasis.

Front Oncol 2018 11;8:159. Epub 2018 May 11.

Department of Pathology, Erasmus Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.3389/fonc.2018.00159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958181PMC
May 2018

Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research-practice gaps, challenges, and insights.

Med Res Rev 2018 01 1;38(1):325-376. Epub 2017 Sep 1.

Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/med.21463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763363PMC
January 2018

The contribution of tumor-associated macrophages in glioma neo-angiogenesis and implications for anti-angiogenic strategies.

Neuro Oncol 2017 Oct;19(11):1435-1446

Department of Pathology, Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, Netherlands; Department of Nephrology and Hypertension, DIGD, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1093/neuonc/nox081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737221PMC
October 2017

Dopamine D2 receptor expression in the corticotroph cells of the human normal pituitary gland.

Endocrine 2017 Aug 13;57(2):314-325. Epub 2016 Oct 13.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s12020-016-1107-2DOI Listing
August 2017

Diffuse Infiltrating Oligodendroglioma and Astrocytoma.

J Clin Oncol 2017 Jul 22;35(21):2394-2401. Epub 2017 Jun 22.

Martin J. van den Bent and Johan M. Kros, Erasmus Medical Center (MC) Cancer Institute; Marion Smits, Erasmus MC, Rotterdam, the Netherlands; and Susan M. Chang, University of California at San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2017.72.6737DOI Listing
July 2017

In Vitro Head-to-Head Comparison Between Octreotide and Pasireotide in GH-Secreting Pituitary Adenomas.

J Clin Endocrinol Metab 2017 06;102(6):2009-2018

Division of Endocrinology, Department of Internal Medicine, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00135DOI Listing
June 2017

CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions.

Arterioscler Thromb Vasc Biol 2017 06 20;37(6):1098-1114. Epub 2017 Apr 20.

From the Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands (I.C., M.B., P.B., D.J.D., C.C.); Division of Internal Medicine and Dermatology, Department of Nephrology and Hypertension, University Medical Center Utrecht, the Netherlands (L.L.-M., C.G.M.v.D., C.C.); Netherlands Heart Institute, Utrecht (L.L.-M.); and Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands (C.Z., J.M.K.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308792DOI Listing
June 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163053PMC
June 2017

A clinical perspective on the 2016 WHO brain tumor classification and routine molecular diagnostics.

Neuro Oncol 2017 05;19(5):614-624

Division of Neuro-Oncology, Department of Neurological Surgery, University of California San Francisco,San Francisco, California

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http://dx.doi.org/10.1093/neuonc/now277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464438PMC
May 2017

Expression site of P2RY12 in residential microglial cells in astrocytomas correlates with M1 and M2 marker expression and tumor grade.

Acta Neuropathol Commun 2017 01 10;5(1). Epub 2017 Jan 10.

Department of pathology, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s40478-016-0405-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223388PMC
January 2017

Diagnostic Detection of Allelic Losses and Imbalances by Next-Generation Sequencing: 1p/19q Co-Deletion Analysis of Gliomas.

J Mol Diagn 2016 09 25;18(5):775-786. Epub 2016 Jul 25.

Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jmoldx.2016.06.002DOI Listing
September 2016

Low beta-arrestin expression correlates with the responsiveness to long-term somatostatin analog treatment in acromegaly.

Eur J Endocrinol 2016 May 17;174(5):651-62. Epub 2016 Feb 17.

Department of Internal MedicineDivision Endocrinology, Erasmus MC, Rotterdam, The Netherlands Pituitary Center RotterdamErasmus MC, Rotterdam, The Netherlands

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http://dx.doi.org/10.1530/EJE-15-0391DOI Listing
May 2016

Myocarditis in patients with subarachnoid hemorrhage: A histopathologic study.

J Crit Care 2016 Apr 11;32:196-200. Epub 2015 Dec 11.

Department of Pathology, ICaR-VU, VU University Medical Center, Amsterdam, The Netherlands; Department of Cardiac Surgery, ICaR-VU, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jcrc.2015.12.005DOI Listing
April 2016

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.

Authors:
Eric M Thompson Thomas Hielscher Eric Bouffet Marc Remke Betty Luu Sridharan Gururangan Roger E McLendon Darell D Bigner Eric S Lipp Sebastien Perreault Yoon-Jae Cho Gerald Grant Seung-Ki Kim Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Kay Ka Wai Li Ho-Keung Ng Yu Yao Toshihiro Kumabe Teiji Tominaga Wieslawa A Grajkowska Marta Perek-Polnik David C Y Low Wan Tew Seow Kenneth T E Chang Jaume Mora Ian F Pollack Ronald L Hamilton Sarah Leary Andrew S Moore Wendy J Ingram Andrew R Hallahan Anne Jouvet Michelle Fèvre-Montange Alexandre Vasiljevic Cecile Faure-Conter Tomoko Shofuda Naoki Kagawa Naoya Hashimoto Nada Jabado Alexander G Weil Tenzin Gayden Takafumi Wataya Tarek Shalaby Michael Grotzer Karel Zitterbart Jaroslav Sterba Leos Kren Tibor Hortobágyi Almos Klekner Bognár László Tímea Pócza Peter Hauser Ulrich Schüller Shin Jung Woo-Youl Jang Pim J French Johan M Kros Marie-Lise C van Veelen Luca Massimi Jeffrey R Leonard Joshua B Rubin Rajeev Vibhakar Lola B Chambless Michael K Cooper Reid C Thompson Claudia C Faria Alice Carvalho Sofia Nunes José Pimentel Xing Fan Karin M Muraszko Enrique López-Aguilar David Lyden Livia Garzia David J H Shih Noriyuki Kijima Christian Schneider Jennifer Adamski Paul A Northcott Marcel Kool David T W Jones Jennifer A Chan Ana Nikolic Maria Luisa Garre Erwin G Van Meir Satoru Osuka Jeffrey J Olson Arman Jahangiri Brandyn A Castro Nalin Gupta William A Weiss Iska Moxon-Emre Donald J Mabbott Alvaro Lassaletta Cynthia E Hawkins Uri Tabori James Drake Abhaya Kulkarni Peter Dirks James T Rutka Andrey Korshunov Stefan M Pfister Roger J Packer Vijay Ramaswamy Michael D Taylor

Lancet Oncol 2016 04 12;17(4):484-495. Epub 2016 Mar 12.

Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045150058
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http://dx.doi.org/10.1016/S1470-2045(15)00581-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907853PMC
April 2016

Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.

Neuro Oncol 2016 Mar 9;18(3):388-400. Epub 2015 Sep 9.

Department of Pathology, Rotterdam, the Netherlands (H.J.D., P.N.A., J.M.K., W.N.M.D.); Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands (P.J.F.); Groupe Hospitalier Pitie Salpetriere, Service de Neurologie Mazarin, Paris, France (M.S., A.I.); Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands (P.W.); Department of Pathology, Free University Medical Center, Amsterdam, the Netherlands (P.W.); Department of Neurology, University Medical Center Groningen, Groningen, the Netherlands (R.E.); Department of Pathology, UMCU, Utrecht, the Netherlands (W.S.); Department of Neurology, St. Elisabeth Hospital, Tilburg, the Netherlands (C.T.); European Organisation for Research and Treatment of Cancer Data Center, Brussels, Belgium (T.G.); Department of Neurology/Neuro-oncology, Erasmus MC Cancer Center, Rotterdam, the Netherlands (M.J.v.d.B.).

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http://dx.doi.org/10.1093/neuonc/nov182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767239PMC
March 2016

Contemporary frameless intracranial biopsy techniques: Might variation in safety and efficacy be expected?

Acta Neurochir (Wien) 2015 Nov 29;157(11):2011-6; discussion 2016. Epub 2015 Aug 29.

Department of Neurosurgery, Brain Tumor Center, Erasmus Medical Center, 's Gravendijkwal 230, Kamer H-703, 3015, CE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00701-015-2543-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604498PMC
November 2015

Brain Tumor Epidemiology - A Hub within Multidisciplinary Neuro-oncology. Report on the 15th Brain Tumor Epidemiology Consortium (BTEC) Annual Meeting, Vienna, 2014.

Clin Neuropathol 2015 Jan-Feb;34(1):40-6

Institute of Neurology, Medical University of Vienna, Austria, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria, Department of Neurosurgery, CHU Montpellier, France, Service of Neurology, Hospital Clínic, University of Barcelona, Spain, German Cancer Research Center DKFZ, Heidelberg, Germany, Division of Child Neurology, Department of Neurology, Stanford University, CA, USA, SwissCore, Brussels, Belgium, Erasmus MC, Rotterdam, The Netherlands, Central Brain Tumor Registry of the US, Hinsdale, IL, USA, Department of Epidemiology and Biostatistics, Department of Neurological Surgery, University of California, San Francisco, Department of Epidemiology, University of California, Los Angeles, CA, Brown School Master of Public Health Program, Washington University in St. Louis, MO, Division of Hematology-Oncology, The Vontz Center for Molecular Studies, University of Cincinnati, OH, Department of Neurology, The Mayo Clinic, Rochester, MN, USA Division of Pediatric Hematology/Oncology, Dalhouse University, Canada, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA, Preventive Medicine, University of Southern California, Los Angeles, CA, Brain Tumor Center, University of Cincinnati, and Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317580PMC
http://dx.doi.org/10.5414/np300846DOI Listing
August 2015

Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas.

Neuro Oncol 2015 Jul 16;17(7):935-41. Epub 2015 Feb 16.

Department of Neurology, Erasmus MC, Rotterdam, Netherlands (M.J.v.d.B., Y.G., K.v.Z., J.P., P.A.S.S., P.J.F.); Department of Pathology, Erasmus MC, Rotterdam, Netherlands (J.M.K.); Department of Neurology, Haaglanden MC, The Hague, Netherlands (M.K., M.T.); EORTC Headquarters, Brussels, Belgium (T.G.); Pathology Department, Leiden University Medical Center, Leiden, Netherlands (S.v.D.).

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http://dx.doi.org/10.1093/neuonc/nov013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762005PMC
July 2015

Evidence-Based Diagnostic Algorithm for Glioma: Analysis of the Results of Pathology Panel Review and Molecular Parameters of EORTC 26951 and 26882 Trials.

J Clin Oncol 2015 Jun 27;33(17):1943-50. Epub 2015 Apr 27.

Johan M. Kros and Karin Huizer, Erasmus Medical Center; Pim French and Martin J. van den Bent, Dr Daniel den Hoed Cancer Center, Rotterdam, the Netherlands; Aurelio Hernández-Laín, Hospital Universitario 12 de Octubre Reseach Institute, Madrid; Teresa Ribalta, Hospital Clínic, University of Barcelona, Barcelona, Spain; Gianluca Marucci, Bellaria Hospital, University of Bologna, Bologna; Bianca Pollo, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Neurologico "C. Besta," Milano, Italy; Alex Michotte, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel; David Jaminé, Nawal Bekka, Denis Lacombe, and Thierry Gorlia, European Organisation for Research and Treatment of Cancer, Brussels, Belgium; and Elisabeth J. Rushing, Institute for Neuropathology, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1200/JCO.2014.59.0166DOI Listing
June 2015

Mutation specific functions of EGFR result in a mutation-specific downstream pathway activation.

Eur J Cancer 2015 May 5;51(7):893-903. Epub 2015 Mar 5.

Dept. of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2015.02.006DOI Listing
May 2015

Circulating glioma biomarkers.

Neuro Oncol 2015 Mar 24;17(3):343-60. Epub 2014 Sep 24.

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands (J.M.K., D.M.M., P.-P.Z.); Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands (L.J.M.D., P.A.E.S.S., T.M.L.); Brain Tumor Center Rotterdam, Erasmus Medical Center, Rotterdam, The Netherlands (J.M.K., D.M.M., L.J.M.D., P.A.E.S.S., T.M.L., P.-P.Z.).

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http://dx.doi.org/10.1093/neuonc/nou207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483097PMC
March 2015

Treatment of large low-grade oligodendroglial tumors with upfront procarbazine, lomustine, and vincristine chemotherapy with long follow-up: a retrospective cohort study with growth kinetics.

J Neurooncol 2015 Jan 26;121(2):365-72. Epub 2014 Oct 26.

Department of Neuro-Oncology/Neurology, Erasmus MC Cancer Institute, Erasmus MC University Medical Center, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands,

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http://dx.doi.org/10.1007/s11060-014-1641-9DOI Listing
January 2015

Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues.

Acta Neuropathol 2014 Dec 7;128(6):879-91. Epub 2014 Oct 7.

Department of Medicine 1 and Comprehensive Cancer Center Vienna, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00401-014-1350-7DOI Listing
December 2014

Clinical spectrum of 4H leukodystrophy caused by POLR3A and POLR3B mutations.

Neurology 2014 Nov 22;83(21):1898-905. Epub 2014 Oct 22.

From the Departments of Child Neurology (N.I.F., M.B., M.S.v.d.K.), Clinical Genetics (R.M.L.v.S., E.S.), and Pathology (M.B.), Neuroscience Campus (N.I.F., M.B., M.S.v.d.K.), and the Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (M.S.v.d.K.), VU University Medical Center, Amsterdam, the Netherlands; the Center for Genetic Medicine Research, Department of Neurology (A.V., A.P.), Children's National Medical Center, Washington, DC; the Institute of Metabolic Disease (R.S.), Baylor Research Institute, Dallas, TX; the Departments of Neurology and Neurosurgery and Human Genetics (B.B.), Montreal Neurological Institute, Canada; the Department of Paediatric Neurology (C.C.-B.), Erasmus University Hospital-Sophia Children's Hospital; the Department of Pathology (J.M.K.), Erasmus Medical Center, Rotterdam, the Netherlands; the Neuroradiology Department (P.S.P.), Centro Hospitalar do Porto, Portugal; the Division of Neurology (D.P.), Children's Hospital of Eastern Ontario, University of Ottawa, Canada; the Department of Paediatric Neurology (S.T.), Royal Belfast Hospital for Sick Children, UK; the Department of Clinical Neurosciences for Children (P.S.), Oslo University Hospital, Ullevål; University of Oslo (P.S.), Norway; the Department of Neurology (T.d.G.), Cincinnati School of Medicine and Cincinnati Children's Hospital Medical Center, OH; INSERM-IECB (S.F.), Pessac, France; the Department of Pediatric Neurology (M.D.), University of British Columbia and British Columbia Children's Hospital, Vancouver, Canada; Kennedy Krieger Institute/Johns Hopkins Medical Institutions (S.N.), Baltimore, MD; and the Departments of Pediatrics, Neurology, and Neurosurgery, Division of Pediatric Neurology (K.G., G.B.), Montreal Children's Hospital, McGill University Health Center, Montreal, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000001002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248461PMC
November 2014

Fast tracking of co-localization of multiple markers by using the nanozoomer slide scanner and NDPViewer.

J Cell Physiol 2014 Aug;229(8):967-73

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/jcp.24538DOI Listing
August 2014

The incidence of postoperative thromboembolic complications following surgical resection of intracranial meningioma. A retrospective study of a large single center patient cohort.

Clin Neurol Neurosurg 2014 Aug 11;123:150-4. Epub 2014 Jun 11.

Department of Neurosurgery, Erasmus MC, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2014.06.001DOI Listing
August 2014

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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http://dx.doi.org/10.1200/JCO.2013.50.9539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948094PMC
March 2014

Metabolic alterations due to IDH1 mutation in glioma: opening for therapeutic opportunities?

Acta Neuropathol Commun 2014 Jan 9;2. Epub 2014 Jan 9.

Department of Pathology, Erasmus Medical Center, Dr, Molewaterplein 50, 3000 CA, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896697PMC
January 2014

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

Acta Neuropathol 2013 Dec 31;126(6):917-29. Epub 2013 Oct 31.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830749PMC
December 2013

Structural and expression differences between the vasculature of pilocytic astrocytomas and glioblastomas.

J Neuropathol Exp Neurol 2013 Dec;72(12):1171-81

From the Departments of Pathology (DM, JMK), BioInformatics (SS, PvdS, AK), and Neurology (PF, TML), Erasmus Medical Center, Rotterdam, The Netherlands.

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December 2013

MGMT-STP27 methylation status as predictive marker for response to PCV in anaplastic Oligodendrogliomas and Oligoastrocytomas. A report from EORTC study 26951.

Clin Cancer Res 2013 Oct 15;19(19):5513-22. Epub 2013 Aug 15.

Authors' Affiliations: Departments of Neurology, Biostatistics, and Pathology, Neuro-Oncology Unit Erasmus MC, Rotterdam; AP-HP, Groupe Hospitalier Pitie Salpêtrière, Service de Neurologie 2 Mazarin and Université Pierre et Marie Curie-Paris 6, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), Paris, France; Department of Pathology, UMCU, Utrecht; Department of Pathology, UMCG, Groningen; Department of Neurology, St. Elisabeth Hospital, Tilburg; Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen; Department of Pathology, Free University Medical Center, Amsterdam, the Netherlands; and European Organization for Research and Treatment of Cancer Data Center, Brussels, Belgium.

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October 2013

Intratumoral, not circulating, endothelial progenitor cells share genetic aberrations with glial tumor cells.

J Cell Physiol 2013 Jul;228(7):1383-90

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

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July 2013

Interlaboratory comparison of IDH mutation detection.

J Neurooncol 2013 Apr 29;112(2):173-8. Epub 2013 Jan 29.

Department of Neurology/Neuro-Oncology, Erasmus MC - Cancer Institute, Groene Hilledijk 301, 3075EA, Rotterdam, the Netherlands.

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April 2013

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683624PMC
August 2012

Cyst-like schwannoma on the eyelid margin.

J Craniofac Surg 2012 Jul;23(4):1215-6

Department of Ophthalmology, Sint Lucas Andreas Hospital, Amsterdam, the Netherlands.

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July 2012

Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.

J Neurooncol 2012 May 7;108(1):195-200. Epub 2012 Mar 7.

Department Neurology/Neuro-oncology Unit, Erasmus MC University Hospital/Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337418PMC
May 2012

Serum levels of pregnancy zone protein are elevated in presymptomatic Alzheimer's disease.

J Proteome Res 2011 Nov 28;10(11):4902-10. Epub 2011 Sep 28.

Department of Neurology, Erasmus Medical Center , Rotterdam, The Netherlands.

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November 2011

A hypermethylated phenotype is a better predictor of survival than MGMT methylation in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951.

Clin Cancer Res 2011 Nov 13;17(22):7148-55. Epub 2011 Sep 13.

Neuro-Oncology Unit, Department of Neurology, Daniel den Hoed Cancer Center/Erasmus Medical Center, Rotterdam, the Netherlands.

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November 2011

Alpha-internexin expression predicts outcome in anaplastic oligodendroglial tumors and may positively impact the efficacy of chemotherapy: European organization for research and treatment of cancer trial 26951.

Cancer 2011 Jul 18;117(13):3014-26. Epub 2011 Jan 18.

Mixed Research Unit, UMR 975, INSERM, National Institute of Health and Medical Research-Pierre and Marie Curie University, Pitie-Salpetriere Group Hospital, Paris, France.

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July 2011

Grading of gliomas: the road from eminence to evidence.

Authors:
Johan M Kros

J Neuropathol Exp Neurol 2011 Feb;70(2):101-9

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

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February 2011

Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo.

Ann Neurol 2010 Dec;68(6):835-44

Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.

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December 2010