Publications by authors named "Johan Ledin"

24Publications

Heparan Sulfate Biosynthesis in Zebrafish.

J Histochem Cytochem 2021 Jan 20;69(1):49-60. Epub 2020 Nov 20.

Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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January 2021

Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish.

Sci Rep 2020 06 23;10(1):10127. Epub 2020 Jun 23.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, S-41345, Gothenburg, Sweden.

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June 2020

Zebrafish embryo as a replacement model for initial biocompatibility studies of biomaterials and drug delivery systems.

Acta Biomater 2019 12 1;100:235-243. Epub 2019 Oct 1.

Deptartment of Engineering Sciences, Division of Applied Materials Science, Uppsala University, Uppsala, Sweden; Department of Surgical Sciences, Orthopaedics, Uppsala University, Sweden. Electronic address:

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December 2019

The Nordic Zebrafish and Husbandry Meeting 2018.

Zebrafish 2019 06 5;16(3):329-330. Epub 2019 Mar 5.

3 Comparative Medicine, Karolinska Institutet, Stockholm, Sweden.

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June 2019

A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish.

Nat Protoc 2016 Dec 27;11(12):2357-2375. Epub 2016 Oct 27.

Developmental Genomics Section, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.

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December 2016

CRISPRz: a database of zebrafish validated sgRNAs.

Nucleic Acids Res 2016 Jan 4;44(D1):D822-6. Epub 2015 Oct 4.

Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

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January 2016

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.

Genome Res 2015 Jul 5;25(7):1030-42. Epub 2015 Jun 5.

Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA;

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July 2015

Chondroitin / dermatan sulfate modification enzymes in zebrafish development.

PLoS One 2015 20;10(3):e0121957. Epub 2015 Mar 20.

Department of Organismal Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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February 2016

The NDST gene family in zebrafish: role of NDST1B in pharyngeal arch formation.

PLoS One 2015 13;10(3):e0119040. Epub 2015 Mar 13.

Dept. of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Husargatan 3, PO Box 582, SE-751 23, Uppsala, Sweden.

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January 2016

Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development.

Dev Dyn 2013 Aug 18;242(8):964-75. Epub 2013 Jun 18.

Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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August 2013

Zebrafish Ext2 is necessary for Fgf and Wnt signaling, but not for Hh signaling.

BMC Dev Biol 2011 Sep 5;11:53. Epub 2011 Sep 5.

European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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September 2011

Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation.

J Biol Chem 2006 Nov 19;281(47):35727-34. Epub 2006 Sep 19.

Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.

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November 2006

HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development.

Development 2005 Nov 12;132(22):4963-73. Epub 2005 Oct 12.

European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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November 2005

Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups.

J Biol Chem 2004 Oct 19;279(41):42355-8. Epub 2004 Aug 19.

Department of Medical Biochemistry and Microbiology, BMC, Box 582, SE-751 23 Uppsala, Sweden.

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October 2004