Publications by authors named "Johan Hoebeke"

61Publications

Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein.

PLoS One 2012 3;7(5):e36233. Epub 2012 May 3.

Laboratorio de Biología Molecular de la Enfermedad de Chagas, Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036233PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343115PMC
January 2013

Anti-β-adrenoceptors autoimmunity causing 'idiopathic' arrhythmias and cardiomyopathy.

Circ J 2012 22;76(6):1345-53. Epub 2012 Mar 22.

Centro di Biomagnetismo - Fisiologia Clinica, Università Cattolica del Sacro Cuore, Roma, Italy.

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http://dx.doi.org/10.1253/circj.cj-11-1374DOI Listing
October 2012

Reciprocal repression between P53 and TCTP.

Nat Med 2011 Dec 11;18(1):91-9. Epub 2011 Dec 11.

Centre National de la Recherche Scientifique-Unité Mixte de Recherche 8113, Laboratoire de Biotechnologie et Pharmacologie génétique Appliquée, École Normale Supérieure, Cachan, France.

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http://www.nature.com/articles/nm.2546
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http://dx.doi.org/10.1038/nm.2546DOI Listing
December 2011

Interaction map of the Trypanosoma cruzi ribosomal P protein complex (stalk) and the elongation factor 2.

J Mol Recognit 2011 Mar-Apr;24(2):359-70. Epub 2010 Dec 13.

Laboratorio de Biología Molecular de la Enfermedad de Chagas (LaBMECh), Instituto de Investigaciones en Ingeniería Genética y Biología Molecular (INGEBI), National Research Council (CONICET), Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/jmr.1089DOI Listing
June 2011

Mechanisms of genetically-based resistance to malaria.

Gene 2010 Nov 22;467(1-2):1-12. Epub 2010 Jul 22.

Fundación Instituto de Inmunología de Colombia, Carrera 50 No 26-20, Bogotá, Colombia.

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http://dx.doi.org/10.1016/j.gene.2010.07.008DOI Listing
November 2010

Assessing protein stability of the dimeric DNA-binding domain of E2 human papillomavirus 18 with molecular dynamics.

Mem Inst Oswaldo Cruz 2010 Mar;105(2):123-6

Centro de Biociencias, Instituto de Estudios Avanzados Carretera Nacional Hoyo de la Puerta, Baruta 1080, Estado Miranda, Venezuela.

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http://dx.doi.org/10.1590/s0074-02762010000200002DOI Listing
March 2010

Immunomodulatory consequences of ODN CpG-polycation complexes.

Methods 2009 Dec 18;49(4):328-33. Epub 2009 Mar 18.

CNRS UPR 9021, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.

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http://dx.doi.org/10.1016/j.ymeth.2009.03.005DOI Listing
December 2009

Cross-talk between anti-beta1-adrenoceptor antibodies in dilated cardiomyopathy and Chagas' heart disease.

Autoimmunity 2008 Sep;41(6):429-33

Laboratorio de Biología Molecular de la Enfermedad de Chagas, Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigación, Ciencia y Tecnica, Buenos Aires, Argentina.

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http://dx.doi.org/10.1080/08916930802031702DOI Listing
September 2008

Small multivalent architectures mimicking homotrimers of the TNF superfamily member CD40L: delineating the relationship between structure and effector function.

J Am Chem Soc 2007 Nov 13;129(44):13480-92. Epub 2007 Oct 13.

Centre National de la Recherche Scientifique, Institut de Biologie Moléculaire et Cellulaire, laboratoire d'Immunologie et Chimie Thérapeutiques, 15 rue René Descartes, 67084 Strasbourg, France.

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http://pubs.acs.org/doi/abs/10.1021/ja073169m
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http://dx.doi.org/10.1021/ja073169mDOI Listing
November 2007

Antibodies against the melanocortin-4 receptor act as inverse agonists in vitro and in vivo.

Am J Physiol Regul Integr Comp Physiol 2007 Jun 22;292(6):R2151-8. Epub 2007 Feb 22.

Applied Pharmacology, Biozentrum, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1152/ajpregu.00878.2006DOI Listing
June 2007

Cooperativity in the interaction of synthetic CD40L mimetics with CD40 and its implication in cell signaling.

Biochemistry 2007 Mar 24;46(11):3482-93. Epub 2007 Feb 24.

CNRS UPR 9021, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moléculaire et Cellulaire, 15 rue René Descartes, 67084 Strasbourg, France.

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http://dx.doi.org/10.1021/bi602434aDOI Listing
March 2007

Heteroclitic properties of mixed alpha- and aza-beta3-peptides mimicking a supradominant CD4 T cell epitope presented by nucleosome.

Mol Immunol 2007 Apr 9;44(11):3024-36. Epub 2007 Feb 9.

Centre National de la Recherche Scientifique, Laboratoire d'Immunologie et Chimie Thérapeutiques, Institut de Biologie Moléculaire et Cellulaire, 15 rue René Descartes, 67000 Strasbourg, France.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900700011
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http://dx.doi.org/10.1016/j.molimm.2006.12.028DOI Listing
April 2007

Peptido-targeting of the mitochondrial transition pore complex for therapeutic apoptosis induction.

Curr Pharm Des 2006 ;12(34):4501-11

CNRS UMR 8159, Université de Versailles / St Quentin, 45, avenue des Etats-Unis, 78035 Versailles, France.

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http://dx.doi.org/10.2174/138161206779010530DOI Listing
January 2007

Influence of dominant HIV-1 epitopes on HLA-A3/peptide complex formation.

Proc Natl Acad Sci U S A 2006 Nov 20;103(48):18208-13. Epub 2006 Nov 20.

Département d'Immunologie, Institut Cochin, F-75014 Paris, France.

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http://dx.doi.org/10.1073/pnas.0609029103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1654130PMC
November 2006

Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII.

J Immunol 2006 Jul;177(2):1355-63

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 681 and Université Pierre et Marie Curie (UPMC)-Paris 6, Institut des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France.

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http://dx.doi.org/10.4049/jimmunol.177.2.1355DOI Listing
July 2006

Design and activity of cationic fullerene derivatives as inhibitors of acetylcholinesterase.

Org Biomol Chem 2006 Jul 25;4(13):2556-62. Epub 2006 May 25.

Institute of Molecular and Cellular Biology, UPR 9021 CNRS, Strasbourg, France.

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http://dx.doi.org/10.1039/b604361eDOI Listing
July 2006

IgGs and Mabs against the beta2-adrenoreceptor block A-V conduction in mouse hearts: A possible role in the pathogenesis of ventricular arrhythmias.

J Mol Cell Cardiol 2006 Jun 11;40(6):829-37. Epub 2006 May 11.

Department of Physiology, Texas Tech University Health Sciences Center, 3601 4th St. Lubbock, TX 79430, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2006.03.430DOI Listing
June 2006

Solid-phase synthesis of CD40L mimetics.

Org Biomol Chem 2006 Apr 10;4(8):1461-3. Epub 2006 Mar 10.

Institut de Biologie Moléculaire et Cellulaire, UPR 9021 CNRS, Immunologie et Chimie Thérapeutiques, 15 Rue René Descartes, 67084 Strasbourg, France.

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http://xlink.rsc.org/?DOI=b601528j
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http://dx.doi.org/10.1039/b601528jDOI Listing
April 2006

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L.

Nat Chem Biol 2005 Dec;1(7):377-82

UPR 9021 CNRS, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moléculaire et Cellulaire, 15 rue René Descartes, F-67084 Strasbourg, France.

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http://dx.doi.org/10.1038/nchembio746DOI Listing
December 2005

52-kDa Ro/SSA epitopes preferentially recognized by antibodies from mothers of children with neonatal lupus and congenital heart block.

Arthritis Res Ther 2006 ;8(1):R4

UPR 9021 Centre National de la Recherche Scientifique, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.

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http://dx.doi.org/10.1186/ar1848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526571PMC
January 2007

Carbon nanotubes: on the road to deliver.

Curr Drug Deliv 2005 Jul;2(3):253-9

UPR 9021, CNRS, Institut de Biologie Moléculaire et Cellulaire, 15 rue René Descartes, F-67084, Strasbourg, France.

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http://dx.doi.org/10.2174/1567201054367959DOI Listing
July 2005

Selective modulation of CD4+ T cells from lupus patients by a promiscuous, protective peptide analog.

J Immunol 2005 Nov;175(9):5839-47

Centre National de la Recherche Scientifique (CNRS), Unité Propre de Recherche 9021, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.

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http://dx.doi.org/10.4049/jimmunol.175.9.5839DOI Listing
November 2005

Fusokine interleukin-2/interleukin-18, a novel potent innate and adaptive immune stimulator with decreased toxicity.

Cancer Res 2005 Oct;65(20):9536-46

Division of Medical and Regulatory Affairs, Molecular Immunology Laboratory, Histology and Animal Facilities Laboratory, Transgene SA, Strasbourg, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0691DOI Listing
October 2005

A high-affinity monoclonal antibody with functional activity against the 5-hydroxytryptaminergic (5-HT4) receptor.

Biochem Pharmacol 2005 Oct;70(7):1009-18

UPR 9021 du C.N.R.S., Immunologie et Chimie Thérapeutiques, I.B.M.C., 15, Rue René Descartes, F-67084 Strasbourg, France.

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http://dx.doi.org/10.1016/j.bcp.2005.07.005DOI Listing
October 2005

Autoantibodies against the serotoninergic 5-HT4 receptor and congenital heart block: a reassessment.

J Autoimmun 2005 Aug;25(1):72-6

UPR9021 du C.N.R.S Immunologie et Chimie Thérapeutiques, I.B.M.C., F-67084 Strasbourg, France.

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http://linkinghub.elsevier.com/retrieve/pii/S089684110500073
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http://dx.doi.org/10.1016/j.jaut.2005.04.005DOI Listing
August 2005

Effects on heart rate of an anti-M2 acetylcholine receptor immune response in mice.

FASEB J 2005 Jun;19(8):943-9

C.N.R.S, UPR 9021, IBMC, Laboratory of Immunological and Therapeutical Chemistry, Strasbourg, France.

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http://www.fasebj.org/doi/10.1096/fj.04-3042com
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http://dx.doi.org/10.1096/fj.04-3042comDOI Listing
June 2005

Identifying and characterising the Plasmodium falciparum merozoite surface protein 10 Plasmodium vivax homologue.

Biochem Biophys Res Commun 2005 Jun;331(4):1178-84

Molecular Biology Department, Fundacion Instituto de Inmunologia de Colombia, Bogota, Colombia.

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http://dx.doi.org/10.1016/j.bbrc.2005.04.031DOI Listing
June 2005

Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors.

J Am Chem Soc 2005 Mar;127(12):4388-96

Centre for Drug Delivery Research and Electron Microscopy Unit, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom.

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http://pubs.acs.org/doi/abs/10.1021/ja0441561
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http://dx.doi.org/10.1021/ja0441561DOI Listing
March 2005

Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties.

J Am Chem Soc 2005 Jan;127(1):58-9

Institut de Biologie Moléculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France.

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http://dx.doi.org/10.1021/ja044293yDOI Listing
January 2005

Modulation of the M2 muscarinic acetylcholine receptor activity with monoclonal anti-M2 receptor antibody fragments.

J Biol Chem 2004 Dec 14;279(53):55697-706. Epub 2004 Oct 14.

CNRS, Unité Propre de Recherche 9021, Institut de Biologie Moléculaire et Cellulaire, Laboratory of Therapeutical Chemistry and Immunology, 15 rue René Descartes, F-67084 Strasbourg, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M407213200
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http://dx.doi.org/10.1074/jbc.M407213200DOI Listing
December 2004

Specific antitumor targetable beta-cyclodextrin-poly(ethylene glycol)-folic acid drug delivery bioconjugate.

Bioconjug Chem 2004 Sep-Oct;15(5):997-1004

Department of Pharmaceutical Sciences, University of Padua, Via F. Marzolo, 5-35131 Padova, Italy.

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http://dx.doi.org/10.1021/bc034186dDOI Listing
February 2005

Characterisation and application of antibodies specific for the long platelet-derived growth factor A and B chains.

Int J Biochem Cell Biol 2004 Nov;36(11):2226-41

Wallenberg Laboratory for Cardiovascular Research, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S135727250400185
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http://dx.doi.org/10.1016/j.biocel.2004.05.001DOI Listing
November 2004

A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain.

J Biol Chem 2004 May 18;279(21):22258-66. Epub 2004 Mar 18.

Laboratoire de Biologie et Physiologie Intégrée (CNRS/GDRE-ITI), Université du Luxembourg, 162A, Avenue de la Faïencerie, L-1511, Luxembourg, France.

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http://dx.doi.org/10.1074/jbc.M400947200DOI Listing
May 2004

Direct evidence that toll-like receptor 9 (TLR9) functionally binds plasmid DNA by specific cytosine-phosphate-guanine motif recognition.

J Biol Chem 2004 Apr 20;279(15):15124-9. Epub 2004 Jan 20.

INSERM U547, Institut Pasteur de Lille, 59019 Lille Cedex, France.

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http://dx.doi.org/10.1074/jbc.M313406200DOI Listing
April 2004

Solid-phase synthesis and characterization of a novel fullerene-peptide derived from histone H3.

Org Biomol Chem 2003 Dec 22;1(23):4141-3. Epub 2003 Oct 22.

Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France.

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http://dx.doi.org/10.1039/b311505dDOI Listing
December 2003

Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses.

Chem Biol 2003 Oct;10(10):961-6

Institut de Biologie Moléculaire et Cellulaire, UPR 9021 CNRS, Immunologie et Chimie Thérapeutiques, 15 Rue René Descartes, 67084 Strasbourg, France.

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http://dx.doi.org/10.1016/j.chembiol.2003.09.011DOI Listing
October 2003

Differential binding of platelet-derived growth factor isoforms to glycosaminoglycans.

Histochem Cell Biol 2003 Nov 14;120(5):371-82. Epub 2003 Oct 14.

Department of Cellular Biology, Faculty of Biology, University of Barcelona, Avenida Diagonal 645, 08028, Barcelona, Spain.

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http://link.springer.com/content/pdf/10.1007/s00418-003-0576
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http://link.springer.com/10.1007/s00418-003-0576-6
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http://dx.doi.org/10.1007/s00418-003-0576-6DOI Listing
November 2003

Immunological similarity between Schistosoma and bovine cathepsin D.

Immunol Lett 2003 Oct;89(1):81-8

Laboratorio de Inmunoparasitologia, Centro de Microbiologia y Biologia Celular, I.V.I.C., Apdo. 21827 Caracas 1020 A, Venezuela.

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http://dx.doi.org/10.1016/s0165-2478(03)00113-5DOI Listing
October 2003

scFv single chain antibody variable fragment as inverse agonist of the beta2-adrenergic receptor.

J Biol Chem 2003 Sep 14;278(38):36740-7. Epub 2003 Jul 14.

CNRS, UPR 9021, Institut de Biologie Moléculaire et Cellulaire, Laboratory of Therapeutical Chemistry and Immunology, F-67084 Strasbourg, France.

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http://dx.doi.org/10.1074/jbc.M306877200DOI Listing
September 2003

Autoantibodies to factor VIII with catalytic activity.

Autoimmun Rev 2003 Jan;2(1):30-5

INSERM, U430, Hôpital Broussais, 96, rue Didot, 75014 Paris, France.

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http://dx.doi.org/10.1016/s1568-9972(02)00126-xDOI Listing
January 2003

Synthesis, structural characterization, and immunological properties of carbon nanotubes functionalized with peptides.

J Am Chem Soc 2003 May;125(20):6160-4

Institute of Molecular and Cellular Biology, UPR 9021 CNRS, 67084 Strasbourg, France.

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http://dx.doi.org/10.1021/ja034342rDOI Listing
May 2003

Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein.

Eur J Biochem 2003 Apr;270(7):1515-27

Department of Immunology, Laboratoire National de Santé, Luxembourg; Fakultät für Chemie und Pharmazie, Universität Tübingen, Germany.

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http://dx.doi.org/10.1046/j.1432-1033.2003.03517.xDOI Listing
April 2003

How biotinylation can interfere with recognition: a surface plasmon resonance study of peptide-antibody interactions.

J Immunol Methods 2003 Mar;274(1-2):149-58

UPR 9021 CNRS Immunologie et Chimie Thérapeutiques, Institut de Biologie Moléculaire et Cellulaire, 15, rue René Descartes, F-67084, Strasbourg, France.

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http://dx.doi.org/10.1016/s0022-1759(02)00517-3DOI Listing
March 2003

Sequence analysis, expression, and paratope characterization of a single-chain Fv fragment for the eukaryote ribosomal P proteins.

Biochem Biophys Res Commun 2003 Feb;301(4):819-24

Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490 (1428), Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/s0006-291x(02)03074-7DOI Listing
February 2003

Characterisation of antibodies and analytes by surface plasmon resonance for the optimisation of a competitive immunoassay based on energy transfer.

Anal Bioanal Chem 2002 Jan 18;372(2):293-300. Epub 2001 Dec 18.

Institut of Physical and Theoretical Chemistry, University of Tübingen, Germany.

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http://dx.doi.org/10.1007/s00216-001-1179-5DOI Listing
January 2002

Monoclonal antibodies and human sera directed to the secreted glycoprotein G of herpes simplex virus type 2 recognize type-specific antigenic determinants.

J Gen Virol 2002 Jan;83(Pt 1):157-165

Department of Virology, Göteborg University, Guldhedsgatan 10 B, S-413 46 Göteborg, Sweden1.

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http://dx.doi.org/10.1099/0022-1317-83-1-157DOI Listing
January 2002