Johan Grunewald

Johan Grunewald

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SpotLight Proteomics-A IgG-Enrichment Phenotype Profiling Approach with Clinical Implications.

Int J Mol Sci 2019 May 1;20(9). Epub 2019 May 1.

Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.3390/ijms20092157DOI Listing
May 2019

Correspondence for "Clinical epidemiology of familial sarcoidosis: A systematic literature review".

Respir Med 2019 May 13. Epub 2019 May 13.

Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.rmed.2019.05.003DOI Listing
May 2019

Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients.

J Leukoc Biol 2019 Apr 11;105(4):797-807. Epub 2019 Feb 11.

Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://doi.wiley.com/10.1002/JLB.5A0718-280RR
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http://dx.doi.org/10.1002/JLB.5A0718-280RRDOI Listing
April 2019

Moving Target - Shifting the Focus to Pulmonary Sarcoidosis as an Autoimmune Spectrum Disorder.

Eur Respir J 2019 Apr 18. Epub 2019 Apr 18.

Respiratory Medicine Unit, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.02153
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http://dx.doi.org/10.1183/13993003.021532018DOI Listing
April 2019

Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study.

Respir Res 2018 Dec 3;19(1):236. Epub 2018 Dec 3.

Division of Physiological Chemistry II, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, 17177, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12931-018-0939-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276236PMC
December 2018

Work ability before and after sarcoidosis diagnosis in Sweden.

Respir Med 2018 Nov 5;144S:S7-S12. Epub 2018 Oct 5.

Karolinska Institutet, Department of Medicine Solna, Division of Clinical Epidemiology, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.rmed.2018.09.016DOI Listing
November 2018

Familial aggregation and heritability of sarcoidosis: a Swedish nested case-control study.

Eur Respir J 2018 08 16;52(2). Epub 2018 Aug 16.

Clinical Epidemiology Division, Dept of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1183/13993003.00385-2018DOI Listing
August 2018

Humoral Immunity to Vimentin in HLA-DRB1*03 Patients With Pulmonary Sarcoidosis.

Front Immunol 2018 9;9:1516. Epub 2018 Jul 9.

Respiratory Medicine Unit, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fimmu.2018.01516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046378PMC
July 2018

Altered Fc galactosylation in IgG is a potential serum marker for chronic lung disease.

ERJ Open Res 2018 Jul 31;4(3). Epub 2018 Jul 31.

Division of Physiological Chemistry I, Dept of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1183/23120541.00033-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066530PMC
July 2018

Enhanced CD8 cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease.

Respir Med 2018 05 13;138S:S38-S44. Epub 2017 Oct 13.

Karolinska Institutet, Center for Infectious Medicine, Department of Medicine Huddinge, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.10.006DOI Listing
May 2018

Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD.

Respir Res 2018 03 8;19(1):40. Epub 2018 Mar 8.

Department of Medicine Solna & Center for Molecular Medicine, Respiratory Medicine Unit, Lung Research Lab L4:01, Karolinska Institutet, 171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12931-017-0695-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842534PMC
March 2018

Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype.

Respir Res 2018 03 8;19(1):39. Epub 2018 Mar 8.

Respiratory Medicine Unit, Department of Medicine Solna & Center for Molecular Medicine, Karolinska Institutet, Lung Research Lab L4:01, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12931-017-0699-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842633PMC
March 2018

Th17-lineage cells in pulmonary sarcoidosis and Löfgren's syndrome: Friend or foe?

J Autoimmun 2018 02 5;87:82-96. Epub 2018 Jan 5.

Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.12.012DOI Listing
February 2018

Sarcoidosis mortality in Sweden: a population-based cohort study.

Eur Respir J 2018 02 21;51(2). Epub 2018 Feb 21.

Clinical Epidemiology Unit, Dept of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1183/13993003.01815-2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886843PMC
February 2018

Shared αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome.

J Immunol 2017 10 21;199(7):2279-2290. Epub 2017 Aug 21.

Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045;

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http://dx.doi.org/10.4049/jimmunol.1700570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675165PMC
October 2017

Mass Cytometry Identifies Distinct Lung CD4 T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis.

Front Immunol 2017 12;8:1130. Epub 2017 Sep 12.

Respiratory Medicine Unit, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fimmu.2017.01130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601005PMC
September 2017

Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis.

PLoS One 2016 30;11(8):e0161669. Epub 2016 Aug 30.

Laboratory of Immunogenomics and Immunoproteomics, Department of Pathological Physiology, Faculty of Medicine and Dentistry Palacky University, Olomouc, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161669PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004853PMC
August 2017

Löfgren's Syndrome: Diagnosis, Management, and Disease Pathogenesis.

Semin Respir Crit Care Med 2017 08 27;38(4):463-476. Epub 2017 Jul 27.

Respiratory Medicine Unit, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1055/s-0037-1602380DOI Listing
August 2017

Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis.

Sci Rep 2017 07 17;7(1):5623. Epub 2017 Jul 17.

Department of Medicine, Respiratory Unit, Karolinska Institutet, Karolinska University Hospital, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-017-05754-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514043PMC
July 2017

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules.

J Allergy Clin Immunol 2017 Apr 23;139(4):1186-1194. Epub 2016 Aug 23.

Unit for Immunology and Allergy, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.05.051DOI Listing
April 2017

Pulmonary Extracellular Vesicles as Mediators of Local and Systemic Inflammation.

Front Cell Dev Biol 2017 26;5:39. Epub 2017 Apr 26.

Unit of Immunology and Allergy, Department of Medicine, Karolinska InstituteStockholm, Sweden.

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http://dx.doi.org/10.3389/fcell.2017.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405144PMC
April 2017

Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays.

Int J Infect Dis 2017 Mar 31;56:167-175. Epub 2017 Jan 31.

Centre for Allogeneic Stem Cell Transplantation (CAST), Karolinska University Hospital, Huddinge, Sweden; Division of Therapeutic Immunology (TIM), Department of Laboratory Medicine (LABMED), Karolinska Institutet, Huddinge 14186, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2017.01.021DOI Listing
March 2017

Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden.

Eur Respir J 2016 12 28;48(6):1690-1699. Epub 2016 Jul 28.

Clinical Epidemiology Unit, Dept of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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http://erj.ersjournals.com/content/erj/early/2016/07/28/1399
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http://dx.doi.org/10.1183/13993003.00477-2016DOI Listing
December 2016

Immune cell activation and cytokine release after stimulation of whole blood with pneumococcal C-polysaccharide and capsular polysaccharides.

Int J Infect Dis 2016 Nov 18;52:1-8. Epub 2016 Jul 18.

Respiratory Medicine Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2016.07.004DOI Listing
November 2016

Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis.

Ann Rheum Dis 2016 09 3;75(9):1722-7. Epub 2015 Nov 3.

Rheumatology Unit, Department of Medicine, Solna, Karolinska University Hospital and Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2015-208216DOI Listing
September 2016

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.

Mol Cell Proteomics 2016 09 24;15(9):3017-29. Epub 2016 Jul 24.

§Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; ‖Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1074/mcp.M116.060764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013314PMC
September 2016

Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.

Eur Respir J 2016 08 26;48(2):484-94. Epub 2016 May 26.

Respiratory Medicine Unit, Dept of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1183/13993003.00092-2016DOI Listing
August 2016

T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis.

Clin Immunol 2016 08 23;169:114-120. Epub 2016 Jun 23.

Respiratory Medicine Unit, Department of Medicine and Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.clim.2016.06.006DOI Listing
August 2016

Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.

Respir Res 2016 06 4;17(1):69. Epub 2016 Jun 4.

Affinity proteomics, SciLifeLab, School of Biotechnology, KTH - Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12931-016-0381-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893268PMC
June 2016

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

Eur Respir J 2016 Mar 19;47(3):898-909. Epub 2015 Nov 19.

Respiratory Medicine Unit, Dept of Medicine, Solna and CMM, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.

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http://dx.doi.org/10.1183/13993003.01209-2015DOI Listing
March 2016

Alterations in the membrane-associated proteome fraction of alveolar macrophages in sarcoidosis.

Sarcoidosis Vasc Diffuse Lung Dis 2016 Mar 29;33(1):17-28. Epub 2016 Mar 29.

Karolinska Institutet.

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March 2016

Immunogenetics of Disease-Causing Inflammation in Sarcoidosis.

Clin Rev Allergy Immunol 2015 Aug;49(1):19-35

Respiratory Medicine Unit, Department of Medicine Solna and CMM, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.

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http://link.springer.com/10.1007/s12016-015-8477-8
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http://dx.doi.org/10.1007/s12016-015-8477-8DOI Listing
August 2015

Reduced expression of peroxisome proliferator-activated receptor alpha in BAL and blood T cells of non-löfgren's sarcoidosis patients.

J Inflamm (Lond) 2015 9;12:28. Epub 2015 Apr 9.

Department of Medicine and CMM, Respiratory Medicine Unit, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12950-015-0071-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428503PMC
May 2015

Proteomic profiling reveals autoimmune targets in sarcoidosis.

Am J Respir Crit Care Med 2015 Mar;191(5):574-83

1 SciLifeLab, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1164/rccm.201407-1341OCDOI Listing
March 2015

A method for generating pulmonary neutrophilia using aerosolized lipopolysaccharide.

J Vis Exp 2014 Dec 15(94). Epub 2014 Dec 15.

Department of Medicine, Solna and CMM, Respiratory Medicine Unit, Karolinska Institutet; Safety Science, Global Regulator Affairs & Patient Safety, AstraZeneca Global Medicines Development.

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http://dx.doi.org/10.3791/51470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396917PMC
December 2014

Elevated exhaled nitric oxide in allergen-provoked asthma is associated with airway epithelial iNOS.

PLoS One 2014 28;9(2):e90018. Epub 2014 Feb 28.

Department of Medicine, Solna, Respiratory Medicine Unit, Karolinska Institutet, Stockholm, Sweden ; Safety Science, Global Regulatory Affairs & Patient Safety, AstraZeneca Global Medicines Development, Mölndal, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090018PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938593PMC
October 2014

Genetics of sarcoidosis.

Semin Respir Crit Care Med 2014 Jun 9;35(3):296-306. Epub 2014 Jul 9.

Division of Pulmonary, Department of Medicine, University Medical Center, Freiburg, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1376860
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http://dx.doi.org/10.1055/s-0034-1376860DOI Listing
June 2014

Genetic determinants of pulmonary fibrosis: evolving concepts.

Lancet Respir Med 2014 May 2;2(5):416-28. Epub 2014 Apr 2.

Imperial College London, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S22132600147004
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http://dx.doi.org/10.1016/S2213-2600(14)70047-5DOI Listing
May 2014

Distribution of T-cell subsets in BAL fluid of patients with mild to moderate COPD depends on current smoking status and not airway obstruction.

Chest 2014 Apr;145(4):711-722

Respiratory Medicine Unit, Department of Medicine Solna and Centre for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden.

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http://journal.publications.chestnet.org/data/Journals/CHEST
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http://linkinghub.elsevier.com/retrieve/pii/S001236921535939
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http://dx.doi.org/10.1378/chest.13-0873DOI Listing
April 2014

T cell receptor-Vβ repertoires in lung and blood CD4+ and CD8+ T cells of pulmonary sarcoidosis patients.

BMC Pulm Med 2014 Mar 22;14:50. Epub 2014 Mar 22.

Respiratory Medicine Unit, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1471-2466-14-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997965PMC
March 2014

Cardiac involvement in Caucasian patients with pulmonary sarcoidosis.

Respir Res 2014 Feb 7;15:15. Epub 2014 Feb 7.

Respiratory Medicine Unit, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1465-9921-15-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922031PMC
February 2014

Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis.

Eur Respir J 2013 Jun 11;41(6):1331-9. Epub 2012 Oct 11.

Dept of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://erj.ersjournals.com/content/erj/41/6/1331.full.pdf
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http://erj.ersjournals.com/lookup/doi/10.1183/09031936.00178
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http://dx.doi.org/10.1183/09031936.00178111DOI Listing
June 2013

Recent advances in the genetics of sarcoidosis.

J Med Genet 2013 May 22;50(5):290-7. Epub 2013 Mar 22.

Department of Medical and Surgical Sciences for Children and Adults, Center for Rare Lung Diseases, University Hospital, via del Pozzo 71, Modena 41124, Italy.

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http://jmg.bmj.com/lookup/doi/10.1136/jmedgenet-2013-101532
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http://dx.doi.org/10.1136/jmedgenet-2013-101532DOI Listing
May 2013

Bronchoalveolar lavage results are independent of season, age, gender and collection site.

PLoS One 2012 31;7(8):e43644. Epub 2012 Aug 31.

Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Solna, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043644PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432041PMC
February 2013

Cell recovery in bronchoalveolar lavage fluid in smokers is dependent on cumulative smoking history.

PLoS One 2012 29;7(3):e34232. Epub 2012 Mar 29.

Division of Respiratory Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034232PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315521PMC
November 2012

Antigen-specific multifunctional T-cells in sarcoidosis patients with Lofgren's syndrome.

Eur Respir J 2012 Jul 19;40(1):110-21. Epub 2011 Dec 19.

Karolinska Institutet, Dept of Medicine, Lung Research Laboratory, L4: 01, Karolinska University Hospital, Solna, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1183/09031936.00166110DOI Listing
July 2012

Health effects of a subway environment in mild asthmatic volunteers.

Respir Med 2012 Jan 12;106(1):25-33. Epub 2011 Oct 12.

Department of Public Health Sciences, Division of Occupational and Environmental Medicine, Karolinska Institutet, Norrbacka, 4th floor, SE-17176 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.rmed.2011.09.008DOI Listing
January 2012

HLA associations and Löfgren's syndrome.

Authors:
Johan Grunewald

Expert Rev Clin Immunol 2012 Jan;8(1):55-62

Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Lung Research Laboratory L4:01, Karolinska University Hospital Solna, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1586/eci.11.76DOI Listing
January 2012

Increased pulmonary Wnt (wingless/integrated)-signaling in patients with sarcoidosis.

Respir Med 2011 Feb 10;105(2):282-91. Epub 2010 Dec 10.

Department of Medicine Solna, Respiratory Medicine Unit, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.rmed.2010.11.018DOI Listing
February 2011

Limited airway effects in mild asthmatics after exposure to air pollution in a road tunnel.

Respir Med 2010 Dec 10;104(12):1912-8. Epub 2010 Jul 10.

Department of Public Health Sciences, Division of Occupational and Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.rmed.2010.06.014DOI Listing
December 2010

Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.

Thorax 2010 Nov 29;65(11):1016-24. Epub 2010 Sep 29.

Department of Medicine, Clinical Allergy Research Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1136/thx.2009.132027DOI Listing
November 2010

Neurotrophins and neurotrophin receptors in pulmonary sarcoidosis - granulomas as a source of expression.

Respir Res 2010 Nov 8;11:156. Epub 2010 Nov 8.

Department of Medicine Solna, Respiratory Medicine Unit, Karolinska Institutet/Karolinska University Hospital Solna, Stockholm, Sweden.

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http://respiratory-research.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/1465-9921-11-156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994818PMC
November 2010

Review: role of genetics in susceptibility and outcome of sarcoidosis.

Authors:
Johan Grunewald

Semin Respir Crit Care Med 2010 Aug 27;31(4):380-9. Epub 2010 Jul 27.

Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1055/s-0030-1262206DOI Listing
August 2010

Smoking, use of moist snuff, and risk of chronic inflammatory diseases.

Am J Respir Crit Care Med 2010 Jun 4;181(11):1217-22. Epub 2010 Mar 4.

Rheumatology Unit, Department of Medicine, Karolinska Universitetssjukhuset Solna, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1164/rccm.200909-1338OCDOI Listing
June 2010

In the eye of the beholder: does the master see the SameSpots as the novice?

J Proteome Res 2010 Mar;9(3):1522-32

Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1021/pr9010298DOI Listing
March 2010

Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients.

Respir Res 2010 Feb 26;11:25. Epub 2010 Feb 26.

Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital Solna, Sweden.

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http://dx.doi.org/10.1186/1465-9921-11-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846896PMC
February 2010

Autoimmune T cell responses to antigenic peptides presented by bronchoalveolar lavage cell HLA-DR molecules in sarcoidosis.

Clin Immunol 2009 Dec 27;133(3):353-63. Epub 2009 Sep 27.

Karolinska Institutet, Department of Medicine, Lung Research Laboratory, L4:01, Karolinska University Hospital, Solna, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.clim.2009.08.008DOI Listing
December 2009

Hypoxia but not cigarette smoke modulates VEGF secretion from human T cells.

Growth Factors 2009 Dec;27(6):352-61

Unit of Respiratory Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden.

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http://dx.doi.org/10.3109/08977190903210863DOI Listing
December 2009

Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.

Respir Res 2009 May 29;10:42. Epub 2009 May 29.

Department of Medicine, Unit of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1465-9921-10-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694180PMC
May 2009

Löfgren's syndrome: human leukocyte antigen strongly influences the disease course.

Am J Respir Crit Care Med 2009 Feb 7;179(4):307-12. Epub 2008 Nov 7.

Department of Medicine, Division of Respiratory Medicine, Lung Research Laboratory L4:01, Karolinska Hospital, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1164/rccm.200807-1082OCDOI Listing
February 2009

Higher monocyte expression of TLR2 and TLR4, and enhanced pro-inflammatory synergy of TLR2 with NOD2 stimulation in sarcoidosis.

J Clin Immunol 2009 Jan 5;29(1):78-89. Epub 2008 Sep 5.

Department of Medicine, Respiratory Medicine Unit, Karolinska Institutet, Lung Research Laboratory L4:01, Karolinska University Hospital, Solna, 171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10875-008-9225-0DOI Listing
January 2009

T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis.

J Immunol 2008 Dec;181(12):8784-96

Department of Medicine, Division of Pulmonary and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700300PMC
http://dx.doi.org/10.4049/jimmunol.181.12.8784DOI Listing
December 2008

Genetics of sarcoidosis.

Authors:
Johan Grunewald

Curr Opin Pulm Med 2008 Sep;14(5):434-9

Division of Respiratory Medicine, Department of Medicine, Karolinska Institute and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1097/MCP.0b013e3283043de7DOI Listing
September 2008

Clinical aspects and immune reactions in sarcoidosis.

Authors:
Johan Grunewald

Clin Respir J 2007 Dec;1(2):64-73

Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1752-699X.2007.2007.00019.xDOI Listing
December 2007

Effects of neurotrophins on human bronchial smooth muscle cell migration and matrix metalloproteinase-9 secretion.

Transl Res 2007 Nov 29;150(5):303-10. Epub 2007 May 29.

Department of Medicine Solna, Division of Respiratory Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.trsl.2007.05.001DOI Listing
November 2007

Coeliac disease and risk of sarcoidosis.

Sarcoidosis Vasc Diffuse Lung Dis 2007 Sep;24(2):121-6

Department of Paediatrics, Orebro University Hospital, Sweden.

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September 2007

Role of CD4+ T cells in sarcoidosis.

Proc Am Thorac Soc 2007 Aug;4(5):461-4

Department of Medicine, Division of Respiratory Medicine, Lung Research Laboratory L4:01, Karolinska University Hospital Solna, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1513/pats.200606-130MSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647597PMC
August 2007

A quantitative proteomic analysis of soluble bronchoalveolar fluid proteins from patients with sarcoidosis and chronic beryllium disease.

Sarcoidosis Vasc Diffuse Lung Dis 2007 Mar;24(1):24-32

Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.

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March 2007

Sex-specific manifestations of Löfgren's syndrome.

Am J Respir Crit Care Med 2007 Jan 5;175(1):40-4. Epub 2006 Oct 5.

Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet Lung Research Laboratory L4:01, Karolinska University Hospital Solna, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1164/rccm.200608-1197OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899259PMC
January 2007

Restricted T cell receptor BV gene usage in the lungs and muscles of patients with idiopathic inflammatory myopathies.

Arthritis Rheum 2007 Jan;56(1):372-83

Karolinska University Hospital at Solna, and Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/art.22293DOI Listing
January 2007

CD4+ T cells in sarcoidosis: targets and tools.

Expert Rev Clin Immunol 2006 Nov;2(6):877-86

Karolinska Institutet/Karolinska University Hospital, Lung Research Laboratory L4:01 Respiratory Medicine Unit, Department of Medicine, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1586/1744666X.2.6.877DOI Listing
November 2006

[Long-term treatment with interferon-alpha can induce sarcoidosis. The connection can be stronger than earlier believed].

Lakartidningen 2006 Jun 28-Jul 11;103(26-27):2045-8

Institutionen für medicin, Solna, Karolinska Institutet.

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August 2006

Differential regulation of neurotrophin expression in human bronchial smooth muscle cells.

Respir Res 2006 Jan 29;7:18. Epub 2006 Jan 29.

Division of Respiratory Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1186/1465-9921-7-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386667PMC
January 2006

[Patient with sarcoidosis and Lofgren syndrome: can the inflammatory reaction be physiologically favourable for healing?].

Lakartidningen 2004 Oct;101(42):3274; author reply 3274

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October 2004

Serum protein pattern in sarcoidosis analysed by a proteomics approach.

Sarcoidosis Vasc Diffuse Lung Dis 2004 Oct;21(3):182-90

Karolinska Institutet, Department of Medicine, Lung Research Laboratory, L4:01, Karolinska Hospital, SE-171 76 Stockholm, Sweden.

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October 2004

[Ankle joint arthritis in sarcoidosis--NSAID a good first choice medication].

Lakartidningen 2004 Sep;101(40):3098-9; author reply 3099

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September 2004

Human leukocyte antigen class I alleles and the disease course in sarcoidosis patients.

Am J Respir Crit Care Med 2004 Mar 4;169(6):696-702. Epub 2003 Dec 4.

Department of Medicine, Division of Respiratory Medicine, Karolinska Hospital, Stockholm, Sweden.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200303-459OC
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http://dx.doi.org/10.1164/rccm.200303-459OCDOI Listing
March 2004

Wheat flour exposure results in recruitment of inflammatory cells in the lungs of healthy individuals.

Am J Ind Med 2003 Jul;44(1):75-82

Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/ajim.10238DOI Listing
July 2003

T-lymphocyte activity in HLA-DR17 positive patients with active and clinically recovered sarcoidosis.

Sarcoidosis Vasc Diffuse Lung Dis 2003 Jun;20(2):110-7

Department of Medicine, Division of Respiratory Medicine, Karolinska Hospital, Stockholm, Sweden.

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June 2003