Publications by authors named "Johan Auwerx"

Sci Adv 2020 Dec 2;6(49). Epub 2020 Dec 2.

Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, Brazil.

Mol Ecol 2020 Nov 21. Epub 2020 Nov 21.

Plant Sciences Unit, Flanders Research Institute for Agriculture, Fisheries and Food, Melle, Belgium.

Nephrol Dial Transplant 2021 Jan;36(1):60-68

Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland.

Diabetes 2021 Jan 21;70(1):119-131. Epub 2020 Oct 21.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China

Cell Rep 2020 Sep;32(13):108203

Laboratory of Integrative Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland. Electronic address:

Am J Transplant 2020 Sep 28. Epub 2020 Sep 28.

Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Research Unit of Liver Transplantation and Transplant Immunology, Chinese Academy of Medical Sciences, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, NHC Key Laboratory of Liver Donor Liver Transplantation, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Nanjing, China.

iScience 2020 Sep 2;23(9):101522. Epub 2020 Sep 2.

Systems Biology Program, Graduate School of Media and Governance, Keio University, Fujisawa, Kanagawa 252-0882, Japan; Health Science Laboratory, Keio Research Institute at SFC, Fujisawa, Kanagawa 252-0882, Japan; Department of Environment and Information Studies, Keio University, Fujisawa, Kanagawa 252-0882, Japan; Department of Internal Medicine, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan; Department of Ophthalmology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan. Electronic address:

J Clin Invest 2020 Nov;130(11):5858-5874

Université de Bourgogne Franche-Comté (UBFC), UMR 1231, INSERM/AgroSup Dijon/Université de Bourgogne, Dijon, France.

EMBO J 2020 Sep 5;39(17):e104671. Epub 2020 Aug 5.

Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

J Am Heart Assoc 2020 08 28;9(15):e015862. Epub 2020 Jul 28.

Laboratory of Oral Microbiota and Systemic Diseases Shanghai Ninth People's HospitalCollege of StomatologyShanghai Jiao Tong University School of Medicine Shanghai China.

Nat Metab 2020 08 6;2(8):688-702. Epub 2020 Jul 6.

Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.

Nat Metab 2019 06 14;1(6):595-603. Epub 2019 Jun 14.

Amazentis SA, EPFL Innovation Park, Bâtiment C, Lausanne, Switzerland.

Nat Metab 2020 01 20;2(1):9-31. Epub 2020 Jan 20.

Laboratory of Integrative Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Nat Metab 2019 12 13;1(12):1219-1225. Epub 2019 Dec 13.

Department of Chemical Biology, Max Planck Institute for Medical Research, Heidelberg, Germany.

Nat Metab 2019 12 9;1(12):1226-1242. Epub 2019 Dec 9.

Laboratory of Systems Biology and Genetics, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Aging Cell 2020 08 21;19(8):e13195. Epub 2020 Jul 21.

Research Center for Endocrine and Metabolic Diseases, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea.

Cell Metab 2020 Aug 13;32(2):215-228.e7. Epub 2020 Jul 13.

Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. Electronic address:

Nat Commun 2020 06 1;11(1):2695. Epub 2020 Jun 1.

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

J Cell Biol 2020 Jul;219(7)

Laboratory for Integrative Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Brain 2020 06;143(6):1686-1696

Université Grenoble Alpes, Inserm, U1216, Grenoble Institut des Neurosciences, 38000 Grenoble, France.

Am J Clin Nutr 2020 08;112(2):413-426

Department of Nutrition and Movement Sciences, School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands.

Cell Rep 2020 03;30(13):4386-4398.e5

UMR 152 Pharma Dev, Université de Toulouse, IRD, UPS, Toulouse, France.

J Fish Biol 2020 Mar 10. Epub 2020 Mar 10.

Research Institute for Nature and Forest, Geraardsbergen, Belgium.

Sci Transl Med 2020 02;12(531)

Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Cell Mol Gastroenterol Hepatol 2020 7;10(1):133-147. Epub 2020 Feb 7.

Laboratory of Environmental Toxicology, Department of Pharmacology, University of California, San Diego, La Jolla, California. Electronic address:

Trends Genet 2020 04 6;36(4):259-272. Epub 2020 Feb 6.

Laboratory of Integrative Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland. Electronic address:

Exp Neurol 2020 05 31;327:113219. Epub 2020 Jan 31.

Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA. Electronic address:

J Mol Cell Cardiol 2020 02 21;139:24-32. Epub 2020 Jan 21.

Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland; Department of Cardiology, University Heart Center, Zurich University Hospital, Zurich, Switzerland. Electronic address:

Neuron 2020 02 16;105(4):630-644.e9. Epub 2019 Dec 16.

Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA; Duke Center for Neurodegeneration and Neurotherapeutics, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address:

Circ Res 2020 02 19;126(4):439-452. Epub 2019 Dec 19.

From the Vanderbilt University Medical Center, Nashville, TN (A.E.D., A.P., L.X., L.A., T.S., M.G.L., F.T.B., D.G.H., S.I.D.).

Sci Rep 2019 Nov 25;9(1):17821. Epub 2019 Nov 25.

Amazentis SA, EPFL Innovation Park, Batiment C, CH-1015, Lausanne, Switzerland.

Genome Res 2019 12 21;29(12):2034-2045. Epub 2019 Nov 21.

Laboratory of Integrative Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.

Science 2019 11 14;366(6467):827-832. Epub 2019 Nov 14.

Laboratory of Integrative Systems Physiology, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

FASEB J 2019 12 1;33(12):13808-13824. Epub 2019 Nov 1.

Institute of Biochemistry, Graz University of Technology, Graz, Austria.

PLoS One 2019 21;14(10):e0224100. Epub 2019 Oct 21.

Animal Science Department, University of Nebraska, Lincoln, Nebraska, United States of America.

EMBO Mol Med 2019 11 18;11(11):e9127. Epub 2019 Sep 18.

Laboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Circ Res 2019 09 15;125(7):707-719. Epub 2019 Aug 15.

Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine, Jinan University, China (W.S., H.W., B.L., D.D., Z.J.).

Free Radic Biol Med 2019 11 10;143:203-208. Epub 2019 Aug 10.

Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil; Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil; Obesity and Comorbidities Research Center - OCRC - IB - UNICAMP, Campinas, Brazil. Electronic address:

Sci Transl Med 2019 07;11(502)

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

PLoS Comput Biol 2019 07 3;15(7):e1007162. Epub 2019 Jul 3.

Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.

Microsyst Nanoeng 2018 7;4. Epub 2018 May 7.

Ecole Polytechnique Fédérale de Lausanne, Laboratory of Microsystems, Lausanne, Switzerland.

Nat Commun 2019 04 5;10(1):1567. Epub 2019 Apr 5.

Department of Biochemistry, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, 951-8510, Japan.

Cell Stem Cell 2019 03;24(3):405-418.e7

Laboratory of Regenerative Hematopoiesis, Swiss Institute for Experimental Cancer Research (ISREC) & Institute of Bioengineering (IBI), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; Service and Central Laboratory of Hematology, Departments of Oncology and of Laboratories, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. Electronic address:

Blood Adv 2019 02;3(4):644-657

Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.

J Lipid Res 2019 04 19;60(4):741-746. Epub 2019 Feb 19.

Laboratory of Integrative Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Mol Genet Metab 2019 04 24;126(4):388-396. Epub 2019 Jan 24.

Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Box 1498, New York, NY 10029, USA. Electronic address:

Nat Rev Drug Discov 2019 04;18(4):255-272

Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Mol Cell 2019 02 11;73(4):775-787.e10. Epub 2019 Jan 11.

Laboratory for Integrative and Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. Electronic address:

Lab Chip 2018 12;19(1):120-135

Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

J Biomed Opt 2018 11;24(2):1-9

Ecole Polytechnique Fédérale de Lausanne (EPFL), Laboratory of Microsystems, Lausanne, Switzerland.

J Cell Physiol 2019 05 11;234(5):6601-6610. Epub 2018 Nov 11.

Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, The Netherlands.

Nature 2018 11 24;563(7731):354-359. Epub 2018 Oct 24.

Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Mol Cell Proteomics 2018 09 26;17(9):1766-1777. Epub 2018 Jun 26.

From the ‡Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich CH-8093, Switzerland;

Cell Syst 2018 06 13;6(6):722-733.e6. Epub 2018 Jun 13.

Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

Cell Syst 2018 06 13;6(6):709-721.e6. Epub 2018 Jun 13.

Laboratory of Integrative and Systems Physiology, École Polytchnique Fédérale de Lausanne, Lausanne 1015, Switzerland. Electronic address:

Sci Rep 2018 06 4;8(1):8548. Epub 2018 Jun 4.

Amazentis SA, EPFL Innovation Park, Batiment C, CH-1015, Lausanne, Switzerland.

Diabetes 2018 07 4;67(7):1310-1321. Epub 2018 May 4.

University Lille, Centre National de la Recherche Scientifique, Institut Pasteur de Lille, UMR 8199 - European Genomic Institute for Diabetes, Lille, France

Nat Commun 2018 04 19;9(1):1551. Epub 2018 Apr 19.

Research Center for Endocrine and Metabolic Diseases, Department of Medical Science, School of Medicine, Chungnam National University, Daejeon, 35015, Korea.

Aging Cell 2018 08 14;17(4):e12751. Epub 2018 Apr 14.

Department of Cell Biology & Molecular Medicine, Rutgers University-New Jersey Medical School, Newark, NJ, USA.

Development 2018 04 13;145(8). Epub 2018 Apr 13.

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, CH-1015, Switzerland

Cardiovasc Res 2018 08;114(10):1324-1334

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, Box 1498, New York, NY, USA.

Cell Rep 2018 03;22(11):2849-2859

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

PLoS One 2018 6;13(3):e0193989. Epub 2018 Mar 6.

Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Elife 2018 02 22;7. Epub 2018 Feb 22.

Department of Molecular and Cellular Biology, University of California, Davis, Davis, United States.

Cardiovasc Res 2018 07;114(8):1178-1188

Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland.

Biochim Biophys Acta Mol Basis Dis 2018 09 2;1864(9 Pt A):2718-2732. Epub 2018 Feb 2.

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address:

J Med Chem 2018 02 26;61(3):745-759. Epub 2018 Jan 26.

Laboratory of Integrative and Systems Physiology, Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne CH-1015 Lausanne, Switzerland.

Nature 2017 12 6;552(7684):187-193. Epub 2017 Dec 6.

Laboratory for Integrative and Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

Cell Syst 2018 Jan 30;6(1):90-102.e4. Epub 2017 Nov 30.

Laboratory for Integrative and Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland. Electronic address:

Nat Commun 2017 11 28;8(1):1818. Epub 2017 Nov 28.

Laboratory for Integrative and Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Station 15, 1015, Lausanne, Switzerland.

Sci Rep 2017 Nov 21;7(1):15928. Epub 2017 Nov 21.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

Mol Metab 2017 11 31;6(11):1429-1442. Epub 2017 Aug 31.

Department of Human Biology and Human Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6200MD, The Netherlands. Electronic address:

Mol Cell 2017 Nov;68(3):540-551.e5

Laboratory of Integrative and Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland. Electronic address:

Nat Commun 2017 10 16;8(1):959. Epub 2017 Oct 16.

CAS Key Laboratory of Molecular Virology & Immunology, Unit of Immune Regulation, Institut Pasteur of Shanghai, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.

Brain Pathol 2018 09 26;28(5):611-630. Epub 2017 Dec 26.

Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), 08908 L'Hospitalet de Llobregat, Barcelona, Spain.

Annu Rev Pharmacol Toxicol 2018 01 27;58:353-389. Epub 2017 Sep 27.

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland; email:

Front Immunol 2017 28;8:1037. Epub 2017 Aug 28.

Infectious Diseases Service, Department of Medicine, Lausanne University Hospital, Epalinges, Switzerland.

Nat Commun 2017 09 7;8(1):480. Epub 2017 Sep 7.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, CH-8032, Zurich, Switzerland.

Gastroenterology 2017 12 30;153(6):1568-1580.e10. Epub 2017 Aug 30.

Department of Medicine, Columbia University, New York, NY. Electronic address:

Integr Biol (Camb) 2017 10;9(10):810-819

Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne, EPFL-STI-IMT-LMIS2, Building BM, Station 17, CH-1015 Lausanne, Switzerland.

EMBO J 2017 09 7;36(18):2670-2683. Epub 2017 Aug 7.

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Nat Commun 2017 07 27;8:15842. Epub 2017 Jul 27.

Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne 1010, Switzerland.

PLoS One 2017 20;12(7):e0181676. Epub 2017 Jul 20.

Laboratoire d'Optique Biomédicale, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

FASEB J 2017 10 7;31(10):4515-4532. Epub 2017 Jul 7.

Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia;

Sci Rep 2017 06 20;7(1):3853. Epub 2017 Jun 20.

Infectious Diseases Service, Department of Medicine, Lausanne University Hospital, CH-1066, Epalinges, Switzerland.

Trends Biochem Sci 2017 09 1;42(9):712-725. Epub 2017 Jun 1.

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. Electronic address:

J Cell Biol 2017 07 31;216(7):2027-2045. Epub 2017 May 31.

Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Cell Metab 2017 May;25(5):1186-1193.e4

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

Hum Mol Genet 2017 07;26(13):2541-2550

Department of Clinical Genetics, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.

Trends Cell Biol 2017 06 6;27(6):453-463. Epub 2017 Mar 6.

Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

Curr Protoc Mouse Biol 2017 Mar 2;7(1):47-54. Epub 2017 Mar 2.

Laboratory for Integrative and Systems Physiology, École Polytechnique Federale de Lausanne, Lausanne, Switzerland.

Proc Natl Acad Sci U S A 2017 02 6;114(8):E1432-E1440. Epub 2017 Feb 6.

Laboratory of Environmental Toxicology, Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093.

Hum Mol Genet 2017 02;26(3):582-598

Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

J Cell Biol 2017 Jan 16;216(1):149-165. Epub 2016 Dec 16.

Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon 301-721, South Korea

J Hepatol 2017 03 29;66(3):589-600. Epub 2016 Oct 29.

Laboratory of Cardiovascular Physiology and Tissue Injury, National Institutes of Health/NIAAA, Bethesda, MD 20852, USA. Electronic address:

Cell Metab 2017 02 1;25(2):301-311. Epub 2016 Dec 1.

Aging and Muscle Metabolism Laboratory, Department of Physiology, University of Lausanne, Lausanne 1005, Switzerland; Institute of Sports Sciences, University of Lausanne, Lausanne 1005, Switzerland; Service of Endocrinology, Diabetology, and Metabolism, Department of Medicine, Lausanne University Hospital, Lausanne 1011, Switzerland. Electronic address:

Sci Transl Med 2016 10;8(361):361ra139

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

Nat Commun 2016 10 12;7:13125. Epub 2016 Oct 12.

Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences and School of Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

Nat Commun 2016 10 11;7:13103. Epub 2016 Oct 11.

Nestlé Institute of Health Sciences (NIHS), Lausanne CH-1015, Switzerland.

Curr Protoc Neurosci 2016 10 3;77:8.37.1-8.37.21. Epub 2016 Oct 3.

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.