Publications by authors named "Joern Toedling"

26Publications

Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.

Authors:
Konstantin Helmsauer Maria E Valieva Salaheddine Ali Rocío Chamorro González Robert Schöpflin Claudia Röefzaad Yi Bei Heathcliff Dorado Garcia Elias Rodriguez-Fos Montserrat Puiggròs Katharina Kasack Kerstin Haase Csilla Keskeny Celine Y Chen Luis P Kuschel Philipp Euskirchen Verena Heinrich Michael I Robson Carolina Rosswog Joern Toedling Annabell Szymansky Falk Hertwig Matthias Fischer David Torrents Angelika Eggert Johannes H Schulte Stefan Mundlos Anton G Henssen Richard P Koche

Nat Commun 2020 11 16;11(1):5823. Epub 2020 Nov 16.

Berlin Institute of Health, Anna-Louisa-Karsch-Str. 2, 10178, Berlin, Germany.

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November 2020

Multiplexed Quantification of Four Neuroblastoma DNA Targets in a Single Droplet Digital PCR Reaction.

Authors:
Constantin Peitz Annika Sprüssel Rasmus B Linke Kathy Astrahantseff Maddalena Grimaldi Karin Schmelz Joern Toedling Johannes H Schulte Matthias Fischer Clemens Messerschmidt Dieter Beule Ulrich Keilholz Angelika Eggert Hedwig E Deubzer Marco Lodrini

J Mol Diagn 2020 Aug 26. Epub 2020 Aug 26.

Department of Pediatric Hematology and Oncology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Neuroblastoma Research Group, Experimental and Clinical Research Center, Berlin, Germany.

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August 2020

Publisher Correction: Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.

Authors:
Richard P Koche Elias Rodriguez-Fos Konstantin Helmsauer Martin Burkert Ian C MacArthur Jesper Maag Rocio Chamorro Natalia Munoz-Perez Montserrat Puiggròs Heathcliff Dorado Garcia Yi Bei Claudia Röefzaad Victor Bardinet Annabell Szymansky Annika Winkler Theresa Thole Natalie Timme Katharina Kasack Steffen Fuchs Filippos Klironomos Nina Thiessen Eric Blanc Karin Schmelz Annette Künkele Patrick Hundsdörfer Carolina Rosswog Jessica Theissen Dieter Beule Hedwig Deubzer Sascha Sauer Joern Toedling Matthias Fischer Falk Hertwig Roland F Schwarz Angelika Eggert David Torrents Johannes H Schulte Anton G Henssen

Nat Genet 2020 Apr;52(4):464

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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April 2020

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.

Authors:
Richard P Koche Elias Rodriguez-Fos Konstantin Helmsauer Martin Burkert Ian C MacArthur Jesper Maag Rocio Chamorro Natalia Munoz-Perez Montserrat Puiggròs Heathcliff Dorado Garcia Yi Bei Claudia Röefzaad Victor Bardinet Annabell Szymansky Annika Winkler Theresa Thole Natalie Timme Katharina Kasack Steffen Fuchs Filippos Klironomos Nina Thiessen Eric Blanc Karin Schmelz Annette Künkele Patrick Hundsdörfer Carolina Rosswog Jessica Theissen Dieter Beule Hedwig Deubzer Sascha Sauer Joern Toedling Matthias Fischer Falk Hertwig Roland F Schwarz Angelika Eggert David Torrents Johannes H Schulte Anton G Henssen

Nat Genet 2020 01 16;52(1):29-34. Epub 2019 Dec 16.

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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January 2020

Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.

Authors:
Theresa M Thole Joern Toedling Annika Sprüssel Sebastian Pfeil Larissa Savelyeva David Capper Clemens Messerschmidt Dieter Beule Stefanie Groeneveld-Krentz Cornelia Eckert Guido Gambara Anton G Henssen Sabine Finkler Johannes H Schulte Anja Sieber Nils Bluethgen Christian R A Regenbrecht Annette Künkele Marco Lodrini Angelika Eggert Hedwig E Deubzer

Int J Cancer 2020 02 1;146(4):1031-1041. Epub 2019 Aug 1.

Department of Pediatric Hematology and Oncology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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February 2020

Prohibitin promotes de-differentiation and is a potential therapeutic target in neuroblastoma.

Authors:
Ian C MacArthur Yi Bei Heathcliff Dorado Garcia Michael V Ortiz Joern Toedling Filippos Klironomos Jana Rolff Angelika Eggert Johannes H Schulte Alex Kentsis Anton G Henssen

JCI Insight 2019 04 18;5. Epub 2019 Apr 18.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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April 2019

Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance.

Authors:
Maria Quanz Eckhard Bender Charlotte Kopitz Sylvia Grünewald Andreas Schlicker Wolfgang Schwede Ashley Eheim Luisella Toschi Roland Neuhaus Carmen Richter Joern Toedling Claudia Merz Ralf Lesche Atanas Kamburov Holger Siebeneicher Marcus Bauser Andrea Hägebarth

Mol Cancer Ther 2018 11 16;17(11):2285-2296. Epub 2018 Aug 16.

Bayer AG, Drug Discovery Pharmaceuticals, Berlin, Germany.

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November 2018

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.

Authors:
Viktor Arnhold Karin Schmelz Jutta Proba Annika Winkler Jasmin Wünschel Joern Toedling Hedwig E Deubzer Annette Künkele Angelika Eggert Johannes H Schulte Patrick Hundsdoerfer

Oncotarget 2018 Jan 18;9(2):2304-2319. Epub 2017 Dec 18.

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Pediatric Hematology/Oncology/Stem Cell Transplantation, Berlin, Germany.

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January 2018

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication.

Authors:
Seong Joo Koo Amaury E Fernández-Montalván Volker Badock Christopher J Ott Simon J Holton Oliver von Ahsen Joern Toedling Sarah Vittori James E Bradner Mátyás Gorjánácz

Oncotarget 2016 10;7(43):70323-70335

Drug Discovery, Bayer Pharma AG, Berlin, Germany.

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October 2016

JNK-dependent gene regulatory circuitry governs mesenchymal fate.

Authors:
Sanjeeb Kumar Sahu Angela Garding Neha Tiwari Sudhir Thakurela Joern Toedling Susanne Gebhard Felipe Ortega Nikolai Schmarowski Benedikt Berninger Robert Nitsch Marcus Schmidt Vijay K Tiwari

EMBO J 2015 Aug 8;34(16):2162-81. Epub 2015 Jul 8.

Institute of Molecular Biology (IMB), Mainz, Germany

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August 2015

Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation.

Authors:
Dominik Fröhlich Wen Ping Kuo Carsten Frühbeis Jyh-Jang Sun Christoph M Zehendner Heiko J Luhmann Sheena Pinto Joern Toedling Jacqueline Trotter Eva-Maria Krämer-Albers

Philos Trans R Soc Lond B Biol Sci 2014 Sep;369(1652)

Molecular Cell Biology, University of Mainz, 55128 Mainz, Germany Focus Programme Translational Neuroscience, University of Mainz, 55128 Mainz, Germany

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September 2014

The intestinal microbiota interferes with the microRNA response upon oral Listeria infection.

Authors:
Cristel Archambaud Odile Sismeiro Joern Toedling Guillaume Soubigou Christophe Bécavin Pierre Lechat Alice Lebreton Constance Ciaudo Pascale Cossart

mBio 2013 Dec 10;4(6):e00707-13. Epub 2013 Dec 10.

Institut Pasteur, Unité des Interactions Bactéries-Cellules, Paris, France.

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December 2013

ncPRO-seq: a tool for annotation and profiling of ncRNAs in sRNA-seq data.

Authors:
Chong-Jian Chen Nicolas Servant Joern Toedling Alexis Sarazin Antonin Marchais Evelyne Duvernois-Berthet Valérie Cognat Vincent Colot Olivier Voinnet Edith Heard Constance Ciaudo Emmanuel Barillot

Bioinformatics 2012 Dec 7;28(23):3147-9. Epub 2012 Oct 7.

Institut Curie, F-75248 Paris, France.

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December 2012

Deep-sequencing protocols influence the results obtained in small-RNA sequencing.

Authors:
Joern Toedling Nicolas Servant Constance Ciaudo Laurent Farinelli Olivier Voinnet Edith Heard Emmanuel Barillot

PLoS One 2012 27;7(2):e32724. Epub 2012 Feb 27.

Institut Curie, Paris, France.

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August 2012

Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer.

Authors:
Armelle Corpet Leanne De Koning Joern Toedling Alexia Savignoni Frédérique Berger Charlène Lemaître Roderick J O'Sullivan Jan Karlseder Emmanuel Barillot Bernard Asselain Xavier Sastre-Garau Geneviève Almouzni

EMBO J 2011 Feb 21;30(3):480-93. Epub 2010 Dec 21.

Institut Curie, UMR218, Nuclear Dynamics and Genome Plasticity, Paris, France.

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February 2011

Girafe--an R/Bioconductor package for functional exploration of aligned next-generation sequencing reads.

Authors:
Joern Toedling Constance Ciaudo Olivier Voinnet Edith Heard Emmanuel Barillot

Bioinformatics 2010 Nov 21;26(22):2902-3. Epub 2010 Sep 21.

Institut Curie, 26 rue d'Ulm, F-75248 Paris, INSERM U900, F-75248 Paris, France.

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November 2010

High-resolution transcription atlas of the mitotic cell cycle in budding yeast.

Authors:
Marina V Granovskaia Lars J Jensen Matthew E Ritchie Joern Toedling Ye Ning Peer Bork Wolfgang Huber Lars M Steinmetz

Genome Biol 2010 1;11(3):R24. Epub 2010 Mar 1.

EMBL - European Molecular Biology Laboratory, Department of Genome Biology, Meyerhofstr, Heidelberg, Germany.

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September 2010

Analyzing ChIP-chip data using bioconductor.

Authors:
Joern Toedling Wolfgang Huber

PLoS Comput Biol 2008 Nov 28;4(11):e1000227. Epub 2008 Nov 28.

EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom.

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November 2008

Combinatorial effects of four histone modifications in transcription and differentiation.

Authors:
Jenny J Fischer Joern Toedling Tammo Krueger Markus Schueler Wolfgang Huber Silke Sperling

Genomics 2008 Jan 8;91(1):41-51. Epub 2007 Nov 8.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany.

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January 2008

Ringo--an R/Bioconductor package for analyzing ChIP-chip readouts.

Authors:
Joern Toedling Oleg Skylar Oleg Sklyar Tammo Krueger Jenny J Fischer Silke Sperling Wolfgang Huber

BMC Bioinformatics 2007 Jun 26;8:221. Epub 2007 Jun 26.

EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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June 2007