Joep Killestein

Joep Killestein

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Joep Killestein

Publications by authors named "Joep Killestein"

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Pharmacodynamic assessment of cell-bound natalizumab on PBMC samples stored in liquid nitrogen.

J Immunol Methods 2019 Oct 12;473:112632. Epub 2019 Jul 12.

Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2019.07.004DOI Listing
October 2019

Randomized trial of daily high-dose vitamin D in patients with RRMS receiving subcutaneous interferon β-1a.

Neurology 2019 Oct 8. Epub 2019 Oct 8.

From the Department of Neurology (R.H., J.S.,), Zuyderland Medical Centre Sittard, Maastricht University Medical Centre; Department of Neurology (J.S.), Canisius Wilhelmina Ziekenhuis, Nijmegen, the Netherlands; Department of Nutritional Sciences (R.V.), University of Toronto, Canada; Akershus University Hospital and University of Oslo (T.H.), Norway; Merck GmbH (K.M.), Vienna, Austria; Service de Neurologie (M.S.), Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; Departments of Neurology (J.K.) and Radiology and Nuclear Medicine (F.B.), VU University Medical Centre, Amsterdam, the Netherlands; Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK; Independent Consultant (M.B.), Krailling, Germany; and U.O.C. Neurologia and Multiple Sclerosis Center (L.M.E.G.), Fondazione Istituto G. Giglio di Cefalù, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000008445DOI Listing
October 2019

Plasma proteome in multiple sclerosis disease progression.

Ann Clin Transl Neurol 2019 Sep 31;6(9):1582-1594. Epub 2019 Jul 31.

Department of Clinical Chemistry, Amsterdam University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/acn3.771DOI Listing
September 2019

Abnormalities and erythroblasts in peripheral blood of multiple sclerosis patients treated with natalizumab.

Mult Scler Relat Disord 2019 Sep 3;36:101382. Epub 2019 Sep 3.

Department of Neurology, Amsterdam Neuroscience, MS Center Amsterdam, Amsterdam University Medical Centers location VUmc, PO Box 7057, de Boelelaan 1007 MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.msard.2019.101382DOI Listing
September 2019

The natalizumab wearing-off effect: End of natalizumab cycle; recurrence of MS symptoms.

Neurology 2019 Sep 24. Epub 2019 Sep 24.

From the Amsterdam UMC (Z.L.E.v.K., D.D., I.D., B.I.L.-W., J.K.), Vrije Universiteit Amsterdam; Departments of Neurology (Z.L.E.v.K., D.D., I.D., J.K.) and Radiology & Nuclear Medicine (I.D.), MS Center Amsterdam, Amsterdam Neuroscience; and Departments of Epidemiology and Biostatistics (B.I.L.-W.) and Immunology (A.d.V., I.A.C., A.t.B., T.R.), Landsteiner Laboratory Sanquin Research, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000008357DOI Listing
September 2019

Serum neurofilaments as candidate biomarkers of natalizumab associated progressive multifocal leukoencephalopathy.

Ann Neurol 2019 Aug 26;86(2):322-324. Epub 2019 Jun 26.

Department of Neurology, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, MS Center Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/ana.25523DOI Listing
August 2019

Emerging safety issues in alemtuzumab-treated MS patients.

Mult Scler 2019 Aug;25(9):1206-1208

Department of Neurology, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458519851219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681426PMC
August 2019

Infratentorial and spinal cord lesions: Cumulative predictors of long-term disability?

Mult Scler 2019 Aug 2:1352458519864933. Epub 2019 Aug 2.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands/Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1177/1352458519864933DOI Listing
August 2019

Anti-natalizumab antibodies during 8 years of natalizumab treatment: effect on natalizumab concentration and α4-integrin receptor saturation.

J Neurol 2019 Jul 19;266(7):1804-1805. Epub 2019 Apr 19.

Department of Neurology, Neuroscience Amsterdam, Amsterdam MS Center, Amsterdam University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://link.springer.com/10.1007/s00415-019-09327-8
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http://dx.doi.org/10.1007/s00415-019-09327-8DOI Listing
July 2019

gMS-Classifier1 does not predict disability progression in multiple sclerosis.

Mult Scler 2019 Jun 31;25(7):1010-1011. Epub 2018 Aug 31.

5 Department of Clinical Chemistry, Amsterdam University Medical Centers, The Netherlands.

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http://dx.doi.org/10.1177/1352458518798048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545617PMC
June 2019

Infusion-related events during natalizumab: No need for post-infusion monitoring.

Mult Scler 2019 Jun 25:1352458519860415. Epub 2019 Jun 25.

Department of Neurology, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1177/1352458519860415DOI Listing
June 2019

Dimethyl fumarate-induced changes in the MS lymphocyte repertoire: No need for subset monitoring.

Neurology 2019 Apr 27;92(15):696-697. Epub 2019 Mar 27.

From the Department of Neurology (J.K.), Amsterdam UMC, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, the Netherlands; and Department of Neurology (A.T.R.), University of Chicago, IL.

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http://dx.doi.org/10.1212/WNL.0000000000007255DOI Listing
April 2019

Gray matter networks and cognitive impairment in multiple sclerosis.

Mult Scler 2019 03 11;25(3):382-391. Epub 2018 Jan 11.

Alzheimer Center and Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517751650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393954PMC
March 2019

Imaging of meningeal inflammation should become part of the routine MRI protocol - No.

Mult Scler 2019 03 4;25(3):331-333. Epub 2018 Sep 4.

MS Center Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands/Department of Neurology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458518799642DOI Listing
March 2019

Performance of PML diagnostic criteria in natalizumab-associated PML: data from the Dutch-Belgian cohort.

J Neurol Neurosurg Psychiatry 2019 Jan 12;90(1):44-46. Epub 2018 Aug 12.

Department of Radiology and Nuclear Medicine, Neuroscience Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jnnp-2018-318261DOI Listing
January 2019

Contactin-1 and contactin-2 in cerebrospinal fluid as potential biomarkers for axonal domain dysfunction in multiple sclerosis.

Mult Scler J Exp Transl Clin 2018 Oct-Dec;4(4):2055217318819535. Epub 2018 Dec 24.

Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, The Netherlands.

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http://dx.doi.org/10.1177/2055217318819535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305953PMC
December 2018

Switching natalizumab to fingolimod within 6 weeks reduces recurrence of disease activity in MS patients.

Mult Scler 2018 10 21;24(11):1453-1460. Epub 2017 Aug 21.

Department of Neurology, Neuroscience Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517726381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174622PMC
October 2018

Effects on Spasticity and Neuropathic Pain of an Oral Formulation of Δ9-tetrahydrocannabinol in Patients WithProgressive Multiple Sclerosis.

Clin Ther 2018 09 9;40(9):1467-1482. Epub 2017 Feb 9.

Centre for Human Drug Research, Leiden, the Netherlands; Department of Neurology and Clinical Neurophysiology, VU University Medical Center, Amsterdam, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S01492918173005
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http://dx.doi.org/10.1016/j.clinthera.2017.01.016DOI Listing
September 2018

Three-Tesla MRI does not improve the diagnosis of multiple sclerosis: A multicenter study.

Neurology 2018 07 20;91(3):e249-e257. Epub 2018 Jun 20.

From the Departments of Neurology (M.H.J.H., J.B., J.K.) and Radiology and Nuclear Medicine (I.D.K., M.L.d.V., M.P.W., F.B.), MS Centre Amsterdam, and Department of Epidemiology and Biostatistics (B.I.L.-W.), VU University Medical Centre; Department of Radiology and Nuclear Medicine (I.D.K.), Onze Lieve Vrouwen Gasthuis, Amsterdam, the Netherlands; Queen Square Multiple Sclerosis Centre (N.C., O.C.) and Institutes of Neurology & Healthcare Engineering (F.B.), UCL Institute of Neurology, London, UK; Department of Neurology and Psychiatry (E.S., P.P.), Sapienza University of Rome, Italy; Department of Neurology (M. Andelova, M. Amann) and Division of Neuroradiology, Department of Radiology (M. Amann, J.M.L.), University Hospital Basel; Medical Image Analysis Centre (M. Amann), Basel, Switzerland; Istituto Neurologico Mediterraneo (P.P.), Neuromed, Pozzilli (IS), Italy; Department of Neurology (C.O.-G.), Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain; National Institute for Health Research (O.C., F.B.), University College London Hospitals (UCLH) Biomedical Research Centre (BRC), UK; Department of Neurosciences (C.G.), San Camillo-Forlanini Hospital, Rome, Italy; and Department of Diagnostic and Interventional Radiology and Nuclear Medicine (C.L.), St. Josef Hospital, Ruhr University, Bochum, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000005825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059032PMC
July 2018

Acute syphilitic meningitis in an HIV-infected patient.

IDCases 2018 7;13:e00423. Epub 2018 Jul 7.

Department of Medical Microbiology and Infection Prevention, VU medical center, Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22142509183012
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http://dx.doi.org/10.1016/j.idcr.2018.e00423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077171PMC
July 2018

The majority of natalizumab-treated MS patients have high natalizumab concentrations at time of re-dosing.

Mult Scler 2018 05 9;24(6):805-810. Epub 2017 May 9.

Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517708464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971363PMC
May 2018

Retinal atrophy in relation to visual functioning and vision-related quality of life in patients with multiple sclerosis.

Mult Scler 2018 05 17;24(6):767-776. Epub 2017 May 17.

Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands/Department of Ophthalmology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands/UCL Institute of Neurology, University College London (UCL), London, UK/Moorfields Eye Hospital, London, UK.

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http://dx.doi.org/10.1177/1352458517708463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971367PMC
May 2018

Response to "Letter to the editor on the paper: The majority of natalizumab-treated MS patients have high natalizumab concentrations at time of re-dosing".

Mult Scler 2018 05 9;24(6):822-823. Epub 2017 Oct 9.

1 Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517734073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971362PMC
May 2018

Inflammatory natalizumab-associated PML: baseline characteristics, lesion evolution and relation with PML-IRIS.

J Neurol Neurosurg Psychiatry 2018 05 15;89(5):535-541. Epub 2017 Nov 15.

Department of Neurology, Neuroscience Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jnnp-2017-316886DOI Listing
May 2018

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment.

Mult Scler 2018 04 15;24(4):472-480. Epub 2017 Mar 15.

Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517699874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987988PMC
April 2018

Cerebral rituximab uptake in multiple sclerosis: A Zr-immunoPET pilot study.

Mult Scler 2018 04 26;24(4):543-545. Epub 2017 Apr 26.

MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands/Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517704507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891689PMC
April 2018

Asymptomatic spinal cord lesions do not predict the time to disability in patients with early multiple sclerosis.

Mult Scler 2018 04 6;24(4):481-490. Epub 2017 Nov 6.

Department of Radiology and Nuclear Medicine, Neuroscience Amsterdam, MS Centre Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517736147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881784PMC
April 2018

Cognitive impairment in patients with multiple sclerosis is associated with atrophy of the inner retinal layers.

Mult Scler 2018 02 1;24(2):158-166. Epub 2017 Feb 1.

Department of Ophthalmology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Department of Neurology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; Moorfields Eye Hospital, London, UK.

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http://dx.doi.org/10.1177/1352458517694090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987993PMC
February 2018

Disease activity following pregnancy-related discontinuation of natalizumab in MS.

Neurol Neuroimmunol Neuroinflamm 2018 Jan 5;5(1):e424. Epub 2017 Dec 5.

Department of Neurology (I.K., Z.L.E.v.K., C.E.L., I.D., C.E.P.v.M., B.A.d.J., B.W.v.O., B.M.J.U., J.K.), Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center; Department of Immunology (T.R.), Landsteiner Laboratory Sanquin Research, Amsterdam; Department of Epidemiology and Biostatistics (B.I.L.-W.), VU University Medical Center; and Department of Radiology & Nuclear Medicine (I.D., M.P.W.), VUmc MS Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1212/NXI.0000000000000424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778770PMC
January 2018

Application of the CSF JCV antibody index to early natalizumab-associated progressive multifocal leukoencephalopathy.

J Neurol Neurosurg Psychiatry 2017 12 10;88(12):1092-1094. Epub 2017 May 10.

Department of Radiology & Nuclear Medicine, Neuroscience Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jnnp-2016-315298DOI Listing
December 2017

Regulator of oligodendrocyte maturation, miR-219, a potential biomarker for MS.

J Neuroinflammation 2017 Dec 4;14(1):235. Epub 2017 Dec 4.

Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1186/s12974-017-1006-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716023PMC
December 2017

Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?

J Neuroinflammation 2017 Dec 21;14(1):257. Epub 2017 Dec 21.

Department of Anatomy and Neurosciences, Amsterdam Neuroscience, VU University Medical Center, Postbus 7057, 1007 MB, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1186/s12974-017-1035-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740592PMC
December 2017

Five cases of malignant melanoma during fingolimod treatment in Dutch patients with MS.

Neurology 2017 08 2;89(9):970-972. Epub 2017 Aug 2.

From the Department of Neurology, Amsterdam Neuroscience, VUmc MS Centre Amsterdam (J.K., C.E.L., B.M.J.U.) and Department of Medical Oncology (A.J.M.v.d.E.), VU University Medical Centre; Department of Neurology (E.L.J.H.), St. Antonius Hospital Utrecht; Department of Neurology (J.v.E.), Jeroen Bosch Hospital, 's-Hertogenbosch; and Department of Neurology (J.P.M.), Rijnstate Hospital, Arnhem, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000004293DOI Listing
August 2017

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

Cancer Cell 2017 08;32(2):238-252.e9

Department of Neurosurgery, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Brain Tumor Center Amsterdam, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, 149 13(th) Street, Charlestown, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381325PMC
August 2017

Natalizumab-associated progressive multifocal leukoencephalopathy is not preceded by elevated drug concentrations.

Mult Scler 2017 Jun 13;23(7):995-999. Epub 2016 Dec 13.

Department of Neurology, Neuroscience Campus Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands.

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http://journals.sagepub.com/doi/10.1177/1352458516684023
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http://dx.doi.org/10.1177/1352458516684023DOI Listing
June 2017

Neutralizing capacity of monoclonal and polyclonal anti-natalizumab antibodies: The immune response to antibody therapeutics preferentially targets the antigen-binding site.

J Allergy Clin Immunol 2017 03 4;139(3):1035-1037.e6. Epub 2016 Oct 4.

Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.09.014DOI Listing
March 2017

Comparison of multiplex platforms for cytokine assessments and their potential use for biomarker profiling in multiple sclerosis.

Cytokine 2017 03 9;91:145-152. Epub 2017 Jan 9.

Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10434666163061
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http://dx.doi.org/10.1016/j.cyto.2016.12.021DOI Listing
March 2017

An observational study of alemtuzumab following fingolimod for multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 10;4(2):e320. Epub 2017 Jan 10.

Department of Neurology (M.W., E.T., N.R.), Institute of Psychological Medicine and Clinical Neuroscience, Cardiff University, University Hospital of Wales; Department of Neurology (O.P.), Morriston Hospital, Heol Maes Eglwys, Morriston, Swansea, UK; Departments of Neurology (Z.I., T.S.) and Clinical Immunology (C.N.), Odense University Hospital, University of Southern Denmark; Department of Neurology (M.D.), The Royal Victoria Infirmary, Newcastle upon Tyne; Department of Neurology (K.P.), Sunderland Royal Hospital, UK; VU University Medical Center (C.v.M., J.K.), Amsterdam, the Netherlands; and Department of Neurology (C.M.), Sahlgrenska Academy at the University of Gothenburg, Institute of Clinical Neuroscience and Physiology, Gothenburg, Sweden.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226279PMC
March 2017

MRI criteria differentiating asymptomatic PML from new MS lesions during natalizumab pharmacovigilance.

J Neurol Neurosurg Psychiatry 2016 10 16;87(10):1138-45. Epub 2016 Aug 16.

Department of Radiology & Nuclear Medicine, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jnnp-2016-313772DOI Listing
October 2016

MRI characteristics of early PML-IRIS after natalizumab treatment in patients with MS.

J Neurol Neurosurg Psychiatry 2016 08 14;87(8):879-84. Epub 2015 Sep 14.

MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jnnp-2015-311411DOI Listing
August 2016

CSF examination still has value in the diagnosis of MS - NO.

Mult Scler 2016 07 8;22(8):995-7. Epub 2016 Apr 8.

MS Center Amsterdam, Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458516641777DOI Listing
July 2016

Multi-parametric structural magnetic resonance imaging in relation to cognitive dysfunction in long-standing multiple sclerosis.

Mult Scler 2016 Apr 24;22(5):608-19. Epub 2015 Jul 24.

Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam, VU University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/1352458515596598DOI Listing
April 2016

Concomitant granule cell neuronopathy in patients with natalizumab-associated PML.

J Neurol 2016 Apr 25;263(4):649-56. Epub 2016 Jan 25.

Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00415-015-8001-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826658PMC
April 2016

Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients.

Neurol Neuroimmunol Neuroinflamm 2016 Apr 27;3(2):e202. Epub 2016 Jan 27.

Department of Neurology (H.H., A.M., M.H., D.R., F.D.), Medical University of Innsbruck, Austria; Department of Arthritis and Clinical Immunology (I.A., C.J.L., R.C.A.), Oklahoma Medical Research Foundation, Oklahoma City; Centro di Riferimento Regionale Sclerosi Multipla (A.B., S.N.), Neurologia 2, Azienda Ospedaliero Universitaria San Luigi Gonzaga, Orbassano, Turin, Italy; Centre d'Esclerosi Múltiple de Catalunya (Cemcat) (M.C., X.M.), Unitat de Neuroimmunologia Clínica, Hospital Universitari Vall d'Hebron, Barcelona, Spain; Queen Mary University London (G.G.), Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK; Clinical Department of Neurology (M.G.), Allgemeines Krankenhaus Linz, Austria; Department of Neurology (M.K., F.F.), Medical University of Graz, Austria; Department of Neurology (J.K.), Vrije Universiteit Medical Center, Amsterdam, the Netherlands; Department of Biomedicines and Neurology (R.L.P.L., M.M.), Clinical Neuroimmunology, University of Basel, University Hospital Basel, Switzerland; Clinical Department of Neurology (F. Schautzer), Landeskrankenhaus Villach, Austria; Danish Multiple Sclerosis Center (F. Sellebjerg, P.S.S.), Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark; and Department of Neurology and Neurological Sciences (L.S.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747480PMC
April 2016

Cannabinoids in the Treatment of Epilepsy.

Authors:
Joep Killestein

N Engl J Med 2016 01;374(1):94

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http://dx.doi.org/10.1056/NEJMc1512758DOI Listing
January 2016

Low JC virus antibody index during natalizumab treatment less safe than assumed?

Mult Scler 2015 Dec 8;21(14):1753-4. Epub 2015 Oct 8.

Department of Neurology and Radiology (MS Center Amsterdam), VU University Medical Center, The Netherlands.

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http://dx.doi.org/10.1177/1352458515611499DOI Listing
December 2015

Longitudinal JCV serology in multiple sclerosis patients preceding natalizumab-associated progressive multifocal leukoencephalopathy.

Mult Scler 2015 Oct 6;21(12):1600-3. Epub 2015 Feb 6.

Department of Neurology, MS Centre Amsterdam, VU Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/1352458514567728DOI Listing
October 2015

Body fluid biomarkers for multiple sclerosis--the long road to clinical application.

Nat Rev Neurol 2015 Oct 22;11(10):585-96. Epub 2015 Sep 22.

Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/nrneurol.2015.173DOI Listing
October 2015

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

Neurol Neuroimmunol Neuroinflamm 2015 Oct 24;2(5):e154. Epub 2015 Sep 24.

Servei de Neurologia-Neuroimmunologia (M.F.B., S.M., J.R., X.M., M.C.), Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain; Institute of Evolutionary Biology (UPF-CSIC) (C.M.-S., X.F., A.N.), PRBB, Barcelona, Spain; National Institute for Bioinformatics (C.M.-S., X.F., A.N.), Universitat Pompeu Fabra, Barcelona, Spain; Servicio de Neurología (L.L., O.F.), Instituto de Neurociencias Clínicas, Hospital Regional Universitario de Málaga, IBIMA, Málaga, Spain; Department of Neurology (U.K.Z.), University of Rostock, Rostock, Germany; Department of Neurology (J.K.), Multiple Sclerosis Centre Amsterdam, Vrije University Medical Centre, Amsterdam, the Netherlands; Pole des neurosciences et INSERM U1043 (D.B.), Université de Toulouse III, Hopital Purpan, Toulouse, France; Neuroinmunología (J.A.G.-M., A.J.S.), Hospital Universitario Puerta de Hierro, Madrid, Spain; Servicio de Neurología (E.U., R.A.-L.), Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain; Department of Neurology and Immunology (L.M.V., J.C.A.-C.), Hospital Ramón y Cajal, IRYCIS, Madrid, Spain; Department of Neurology (J.L.-S.), John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute (J.L.-S.), University Newcastle, Australia; University Newcastle (J.L.-S.), Callaghan Campus, Australia; Neurogenomiks Group (K.V.), Universidad del País Vasco (UPV/EHU), Leioa, Spain; IKERBASQUE (K.V.), Basque Foundation for Science, Bilbao, Spain; Achucarro Basque Center for Neuroscience (K.V.), Zamudio, Spain; Servicio de Neurología (A.R.-A.), Hospital de Basurto, Bilbao, Spain; Clinic of Neurology (J.S.D.), Clinical Centre of Serbia (CCS), Faculty of Medicine, University of Belgrade, Serbia; Laboratory of Genetics of Neurological Complex Disorders and Department of Neuro-rehabilitation (F.M.B

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http://dx.doi.org/10.1212/NXI.0000000000000154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582905PMC
October 2015

MRI pattern in asymptomatic natalizumab-associated PML.

J Neurol Neurosurg Psychiatry 2015 Jul 9;86(7):793-8. Epub 2014 Sep 9.

Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://jnnp.bmj.com/content/early/2014/09/09/jnnp-2014-30863
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http://jnnp.bmj.com/cgi/doi/10.1136/jnnp-2014-308630
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http://dx.doi.org/10.1136/jnnp-2014-308630DOI Listing
July 2015

Unraveling the neuroimaging predictors for motor dysfunction in long-standing multiple sclerosis.

Neurology 2015 Jul 26;85(3):248-55. Epub 2015 Jun 26.

From the Departments of Radiology and Nuclear Medicine (M.D., M.D.S., M.P.W., F.B.), Anatomy and Neurosciences (M.D., J.J.G.G.), Neurology (B.M.J.U., P.K.T., L.J.B., J.K.), and Physics and Medical Technology (P.J.W.P.), Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000001756DOI Listing
July 2015

Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature.

J Neurol 2015 Jan 9;262(1):65-73. Epub 2014 Oct 9.

Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, De Boelelaan 117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00415-014-7530-5DOI Listing
January 2015

The effect of prolonged natalizumab treatment on anxiety and safety in JC virus-seropositive MS patients; a follow-up study.

Mult Scler 2014 Oct 11;20(12):1668-9. Epub 2014 Aug 11.

VU Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458514543341DOI Listing
October 2014

What explains gray matter atrophy in long-standing multiple sclerosis?

Radiology 2014 Sep 23;272(3):832-42. Epub 2014 Apr 23.

From the Departments of Radiology and Nuclear Medicine (M.D.S., M.D., F.B., H.V.), Anatomy and Neurosciences (M.D., J.J.G.G.), Physics and Medical Technology (P.J.W.P., H.V.), and Neurology (L.J.B., P.K.T., J.K., B.M.J.U.), Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1148/radiol.14132708DOI Listing
September 2014

Cerebrospinal fluid apolipoprotein E and phospholipid transfer protein activity are reduced in multiple sclerosis; relationships with the brain MRI and CSF lipid variables.

Mult Scler Relat Disord 2014 Jul;3(4):533-541

Neurological Laboratory, Department of Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.msard.2014.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061752PMC
July 2014

Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?

J Neurol 2014 Jun 6;261(6):1139-43. Epub 2014 Apr 6.

Department of Radiology, MS Center Amsterdam, Nuclear Medicine and PET Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands,

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http://dx.doi.org/10.1007/s00415-014-7336-5DOI Listing
June 2014

Progressive multifocal leukoencephalopathy after natalizumab discontinuation: few and true?

Ann Neurol 2014 Mar 7;75(3):462. Epub 2014 Mar 7.

MS Center Amsterdam, Department of Radiology, Nuclear Medicine, and PET Research, VU University Medical Center, Amsterdam, the Netherlands.

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http://doi.wiley.com/10.1002/ana.24110
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March 2014

Safety, anxiety and natalizumab continuation in JC virus-seropositive MS patients.

Mult Scler 2014 Jan 4;20(1):108-11. Epub 2013 Jul 4.

Department of Neurology (MS Center Amsterdam), VU University Medical Center, The Netherlands.

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http://dx.doi.org/10.1177/1352458513495582DOI Listing
January 2014

The impact of pre-analytical variables on the stability of neurofilament proteins in CSF, determined by a novel validated SinglePlex Luminex assay and ELISA.

J Immunol Methods 2014 Jan 22;402(1-2):43-9. Epub 2013 Nov 22.

Department of Clinical Chemistry, VU University Medical Center Amsterdam, PO Box 7057, 1007MB Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2013.11.008DOI Listing
January 2014

The chameleon of neuroinflammation: magnetic resonance imaging characteristics of natalizumab-associated progressive multifocal leukoencephalopathy.

Mult Scler 2013 Dec 5;19(14):1826-40. Epub 2013 Nov 5.

Department of Radiology, Nuclear Medicine & PET Research, University Medical Center, The Netherlands.

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http://dx.doi.org/10.1177/1352458513510224DOI Listing
December 2013

Drug interference in immunogenicity assays depends on valency.

J Pharm Biomed Anal 2013 Nov 30;85:179-85. Epub 2013 Jul 30.

Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jpba.2013.07.022DOI Listing
November 2013

Chronic lymphocytic inflammation with Pontine perivascular enhancement responsive to steroids and fatal B-cell lymphoma--reply.

JAMA Neurol 2013 Nov;70(11):1459-60

MS Center Amsterdam, Department of Neurology, VU University Medical Center, Amsterdam, the Netherlands.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2013.4757DOI Listing
November 2013

Should CLIPPERS be considered a Prelymphoma state or a new Inflammatory disease.

JAMA Neurol 2013 Sep;70(9):1201

MS Center Amsterdam, Department of Neurology, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamaneurol.2013.3855DOI Listing
September 2013

Case reports of PML in patients treated for psoriasis.

N Engl J Med 2013 09;369(11):1081-2

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http://dx.doi.org/10.1056/NEJMc1307680DOI Listing
September 2013

Fatal B-cell lymphoma following chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids.

JAMA Neurol 2013 Jul;70(7):915-8

Department of Neurology, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamaneurol.2013.2016DOI Listing
July 2013

Natalizumab remains detectable in patients with multiple sclerosis long after treatment is stopped.

Mult Scler 2012 Jun 19;18(6):899-901. Epub 2011 Dec 19.

Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458511431073DOI Listing
June 2012

The physiological variation of the retinal nerve fiber layer thickness and macular volume in humans as assessed by spectral domain-optical coherence tomography.

Invest Ophthalmol Vis Sci 2012 Mar 9;53(3):1251-7. Epub 2012 Mar 9.

Department of Neurology, MS Center, VU University Medical Center, De Boelelaan 1118, 1081 HZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1167/iovs.11-8209DOI Listing
March 2012

Antibodies against aquaporin-4 in neuromyelitis optica: distinction between recurrent and monophasic patients.

Mult Scler 2011 Dec 9;17(12):1527-30. Epub 2011 Aug 9.

Department of Neurology, MS Centre ErasMS, Erasmus University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/1352458511412995DOI Listing
December 2011

Oral treatment for multiple sclerosis.

Lancet Neurol 2011 Nov;10(11):1026-34

Department of Neurology, Multiple Sclerosis Centre Amsterdam, Vrije University Medical Centre, Amsterdam, Netherlands.

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November 2011

Differential effect of drug interference in immunogenicity assays.

J Immunol Methods 2011 Sep 29;372(1-2):196-203. Epub 2011 Jul 29.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory AMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jim.2011.07.019DOI Listing
September 2011

Measurement of serum levels of natalizumab, an immunoglobulin G4 therapeutic monoclonal antibody.

Anal Biochem 2011 Apr 7;411(2):271-6. Epub 2011 Jan 7.

Sanquin Research, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ab.2011.01.001DOI Listing
April 2011

Determinants of interferon β efficacy in patients with multiple sclerosis.

Nat Rev Neurol 2011 Apr 1;7(4):221-8. Epub 2011 Mar 1.

Department of Neurology (MS Center Amsterdam), VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.

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http://www.nature.com/articles/nrneurol.2011.22
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http://dx.doi.org/10.1038/nrneurol.2011.22DOI Listing
April 2011

Natalizumab drug holiday in multiple sclerosis: poorly tolerated.

Ann Neurol 2010 Sep;68(3):392-5

Department of Neurology, MS Center Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/ana.22074DOI Listing
September 2010

Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.

Mult Scler 2010 Jun 8;16(6):652-9. Epub 2010 Apr 8.

Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458510364633DOI Listing
June 2010