Joel M Kremer

Joel M Kremer

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Joel M Kremer

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Differing contribution of methotrexate polyglutamates to adalimumab blood levels as compared with etanercept.

Ann Rheum Dis 2019 Sep 18;78(9):1285-1286. Epub 2019 Mar 18.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/annrheumdis-2018-214860DOI Listing
September 2019

Outcomes of infliximab dose escalation in patients with rheumatoid arthritis.

Clin Rheumatol 2019 Sep 2;38(9):2501-2508. Epub 2019 May 2.

Janssen Scientific Affairs, LLC, 800 Ridgeview Drive, Horsham, PA, 19044, USA.

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http://dx.doi.org/10.1007/s10067-019-04543-zDOI Listing
September 2019

Machine learning to predict anti-TNF drug responses of rheumatoid arthritis patients by integrating clinical and genetic markers.

Arthritis Rheumatol 2019 Jul 24. Epub 2019 Jul 24.

Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, China, 400000.

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http://dx.doi.org/10.1002/art.41056DOI Listing
July 2019

Predictors of Achieving Remission among Patients with Psoriatic Arthritis Initiating a Tumor Necrosis Factor Inhibitor.

J Rheumatol 2019 May 15;46(5):475-482. Epub 2019 Jan 15.

From the University of Pennsylvania, Philadelphia, Pennsylvania; Corrona Research Foundation; New York University Hospital for Joint Diseases, New York, New York; University of Alabama at Birmingham, Birmingham, Alabama; University of Massachusetts, Worcester; Brigham and Women's Hospital, Boston, Massachusetts; University of California San Diego, San Diego, California; Albany Medical College, Albany, New York; Swedish Medical Center; University of Washington, Seattle, Washington, USA.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.171034
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http://dx.doi.org/10.3899/jrheum.171034DOI Listing
May 2019

Safety and efficacy of ixekizumab in patients with PsA and previous inadequate response to TNF inhibitors: week 52 results from SPIRIT-P2.

Rheumatology (Oxford) 2018 11;57(11):2001-2011

Department of Medicine, University of Queensland, Rheumatology Research Unit Sunshine Coast, Queensland, Australia.

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http://dx.doi.org/10.1093/rheumatology/key182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199530PMC
November 2018

Do Poor Prognostic Factors in Rheumatoid Arthritis Affect Treatment Choices and Outcomes? Analysis of a US Rheumatoid Arthritis Registry.

J Rheumatol 2018 10 1;45(10):1353-1360. Epub 2018 Jul 1.

From Bristol-Myers Squibb, Princeton, New Jersey; Corrona LLC, Southborough, Massachusetts; Albany Medical College and The Center for Rheumatology, Albany, New York; University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.171050
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http://dx.doi.org/10.3899/jrheum.171050DOI Listing
October 2018

Superior Displacement of the Dens in a Patient With Rheumatoid Arthritis.

J Clin Rheumatol 2018 Mar;24(2):95-96

From the Division of Rheumatology, Department of Medicine, Albany Medical Center.

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http://dx.doi.org/10.1097/RHU.0000000000000567DOI Listing
March 2018

Influence of obesity, age, and comorbidities on the multi-biomarker disease activity test in rheumatoid arthritis.

Semin Arthritis Rheum 2018 02 2;47(4):472-477. Epub 2017 Aug 2.

Corrona Research Foundation, Albany, NY.

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http://dx.doi.org/10.1016/j.semarthrit.2017.07.010DOI Listing
February 2018

Design characteristics of the Corrona Japan rheumatoid arthritis registry.

Mod Rheumatol 2018 Jan 27;28(1):95-100. Epub 2017 Apr 27.

g The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health , Kitakyushu , Japan.

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http://dx.doi.org/10.1080/14397595.2017.1317383DOI Listing
January 2018

Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate.

Ann Rheum Dis 2018 01 8;77(1):e4. Epub 2017 Jun 8.

Department of Rheumatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/annrheumdis-2017-211632DOI Listing
January 2018

A Randomized Phase IIb Study of Mavrilimumab and Golimumab in Rheumatoid Arthritis.

Arthritis Rheumatol 2018 01;70(1):49-59

Charité-University Medicine Berlin, Free University of Berlin, and Humboldt University of Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/art.40323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767745PMC
January 2018

Effect of Anticitrullinated Protein Antibody Status on Response to Abatacept or Antitumor Necrosis Factor-α Therapy in Patients with Rheumatoid Arthritis: A US National Observational Study.

J Rheumatol 2018 01 1;45(1):32-39. Epub 2017 Nov 1.

From the University of Massachusetts Medical School, Worcester; Corrona LLC, Southborough, Massachusetts; Bristol-Myers Squibb, Princeton, New Jersey; Albany Medical College and The Center for Rheumatology, Albany, New York.

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http://dx.doi.org/10.3899/jrheum.170007DOI Listing
January 2018

Fish Oil and Inflammation - A Fresh Look.

Authors:
Joel M Kremer

J Rheumatol 2017 06;44(6):713-716

Pfaff Family Professor of Medicine, Albany Medical College; Director of Research, The Center for Rheumatology, Albany, New York, USA.

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http://dx.doi.org/10.3899/jrheum.161551DOI Listing
June 2017

The Corrona US registry of rheumatic and autoimmune diseases.

Authors:
Joel M Kremer

Clin Exp Rheumatol 2016 Sep-Oct;34(5 Suppl 101):S96-S99. Epub 2016 Oct 19.

Pfaff Family Professor of Medicine, Albany Medical College, and Director of Research, The Center for Rheumatology, Albany, NY, USA.

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February 2017

Clinical efficacy and safety maintained up to 5 years in patients with rheumatoid arthritis treated with tocilizumab in a randomised trial.

Clin Exp Rheumatol 2016 Jul-Aug;34(4):625-33. Epub 2016 Apr 15.

Metroplex Clinical Research Center, Dallas, Texas, USA.

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September 2016

Bias? Not so fast.

Authors:
Joel M Kremer

Ann Rheum Dis 2016 09 20;75(9):1581-2. Epub 2016 Apr 20.

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http://dx.doi.org/10.1136/annrheumdis-2016-209505DOI Listing
September 2016

Fish oil for OA? Don't give up yet.

Authors:
Joel M Kremer

Ann Rheum Dis 2016 07 3;75(7):e42. Epub 2016 Feb 3.

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http://dx.doi.org/10.1136/annrheumdis-2016-209168DOI Listing
July 2016

Agreement between Rheumatologist and Patient-reported Adherence to Methotrexate in a US Rheumatoid Arthritis Registry.

J Rheumatol 2016 06 1;43(6):1027-9. Epub 2016 May 1.

From the University of Alabama at Birmingham, Birmingham, Alabama; Consortium of Rheumatology Researchers of North America (CORRONA) LLC, Southborough; University of Massachusetts, Worcester, Massachusetts, USA.J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham; A. Bharat, MD, MPH, University of Alabama at Birmingham; L. Chen, PhD, University of Alabama at Birmingham; J.D. Greenberg, MD, MPH, CORRONA LLC; L. Harrold, MD, MPH, University of Massachusetts; J.M. Kremer, MD, CORRONA LLC; T. Sommers, MS, CORRONA LLC; D. Pappas, MD, MPH, CORRONA LLC.

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http://dx.doi.org/10.3899/jrheum.151136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891269PMC
June 2016

Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures.

RMD Open 2016 9;2(1):e000287. Epub 2016 Jun 9.

Division of Rheumatology, Department of Medicine , Albany Medical College, and The Center for Rheumatology (JMK), The New York State Department of Health (DAL) the Albany College of Pharmacy (RH), and The University of Glasgow (IBM) , Albany, New York , USA.

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http://dx.doi.org/10.1136/rmdopen-2016-000287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913203PMC
June 2016

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.

PLoS One 2015 7;10(4):e0122271. Epub 2015 Apr 7.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122271PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388675PMC
March 2016

Comparative effectiveness of biologic monotherapy versus combination therapy for patients with psoriatic arthritis: results from the Corrona registry.

RMD Open 2015 30;1(1):e000181. Epub 2015 Dec 30.

Epidemiology and Outcomes Research, Corrona, LLC, Southborough, Massachusetts, USA; Division of Rheumatology, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1136/rmdopen-2015-000181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716450PMC
January 2016

Can Methotrexate Prevent Knee Arthroplasties in Patients with Rheumatoid Arthritis?

Authors:
Joel M Kremer

J Rheumatol 2015 Dec;42(12):2217-8

Pfaff Family Professor of Medicine, Albany Medical College, Director of Research, Center for Rheumatology, 1367 Washington Ave., Albany, New York 12206, USA.

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http://dx.doi.org/10.3899/jrheum.151104DOI Listing
December 2015

Considerations on the appropriateness of the John Cunningham virus antibody assay use in patients with rheumatoid arthritis.

Semin Arthritis Rheum 2015 Oct 17;45(2):163-6. Epub 2015 Jun 17.

The Center for Rheumatology, Albany Medical Center, LLP, 1367 Washington Ave, Suite 101, Albany, NY 12206. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2015.06.003DOI Listing
October 2015

Effectiveness of Rituximab for the Treatment of Rheumatoid Arthritis in Patients with Prior Exposure to Anti-TNF: Results from the CORRONA Registry.

J Rheumatol 2015 Jul 1;42(7):1090-8. Epub 2015 May 1.

From the University of Massachusetts Medical School, Worcester; Corrona LLC, Southborough, Massachusetts; Genentech Inc., South San Francisco, California; Albany Medical College and The Center for Rheumatology, Albany; New York University (NYU) School of Medicine, New York, New York, USA.L.R. Harrold, MD, MPH, Department of Medicine, University of Massachusetts Medical School; G.W. Reed, PhD, Department of Medicine, University of Massachusetts Medical School, and Corrona LLC; A. Shewade, MS, Genentech Inc.; R. Magner, MPH, Department of Medicine, University of Massachusetts Medical School; K.C. Saunders, MS, Corrona LLC; A. John, BSN, MPH, Genentech Inc.; J.M. Kremer, MD, Department of Rheumatology, Albany Medical College, and The Center for Rheumatology; J.D. Greenberg, MD, MPH, Department of Medicine, Division of Rheumatology, NYU School of Medicine.

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http://dx.doi.org/10.3899/jrheum.141043DOI Listing
July 2015

Characteristics Associated with Biologic Monotherapy Use in Biologic-Naive Patients with Rheumatoid Arthritis in a US Registry Population.

Rheumatol Ther 2015 Jun 27;2(1):85-96. Epub 2015 Jan 27.

Albany Medical College and The Center for Rheumatology, 1367 Washington Ave, Suite 101, Albany, NY, 12206, USA.

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http://dx.doi.org/10.1007/s40744-015-0008-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883255PMC
June 2015

Evaluation of the effect of tofacitinib on measured glomerular filtration rate in patients with active rheumatoid arthritis: results from a randomised controlled trial.

Arthritis Res Ther 2015 Apr 6;17:95. Epub 2015 Apr 6.

National Institute for Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1186/s13075-015-0612-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445792PMC
April 2015

Still trying to understand methotrexate.

Authors:
Joel M Kremer

J Rheumatol 2014 Nov;41(11):2099-101

Pfaff Family Professor of Medicine, Albany Medical College, Director of Research, The Center for Rheumatology, Albany, New York, USA.

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http://dx.doi.org/10.3899/jrheum.141081DOI Listing
November 2014

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.

PLoS One 2014 10;9(2):e87645. Epub 2014 Feb 10.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087645PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919745PMC
October 2014

Long-term safety and efficacy of abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: a 7-year extended study.

Clin Exp Rheumatol 2014 Jul-Aug;32(4):553-62. Epub 2014 Jul 8.

Department of Development and Regeneration, Neuro-musculo-skeletal Research Unit, KU Leuven, Belgium.

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October 2014

Longterm safety, efficacy, and inhibition of structural damage progression over 5 years of treatment with abatacept in patients with rheumatoid arthritis in the abatacept in inadequate responders to methotrexate trial.

J Rheumatol 2014 Jun 1;41(6):1077-87. Epub 2014 May 1.

From the Center for Rheumatology, Albany Medical College, Albany, New York; Spire Sciences Inc., Boca Raton, Florida, USA; Division of Rheumatology, University of Alberta Hospital, Edmonton, Alberta, Canada; Division of Rheumatic and Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, Leeds, UK; Regional Unit of Rheumatology, Faculty of Medicine and Central Hospital, University of San Luis Potosí, San Luis Potosí, México; Service de Rhumatologie, CHU de Strasbourg, Hôpital de Hautepierre, Strasbourg, France; Bristol-Myers Squibb, Princeton, New Jersey, USA; Department of Rheumatology, Universitaire Ziekenhuizenn Leuven, Leuven, Belgium; UCSF/Synarc, San Francisco, California, USA.Professional medical writing and editorial assistance funded by Bristol-Myers Squibb, Princeton, New Jersey, USA, and provided by Eve Guichard BSc (hons) of Caudex Medical, Oxford, UK.J.M. Kremer, MD, Center for Rheumatology, Albany Medical College; C. Peterfy, MD, PhD, FRCPC, Spire Sciences Inc.; A.S. Russell, FRCP, FRCPC, Division of Rheumatology, University of Alberta Hospital; P. Emery, MA, MD, FRCP, FRCPE, Division of Rheumatic and Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust; C. Abud-Mendoza, MD, Regional Unit of Rheumatology, Faculty of Medicine and Central Hospital, University of San Luis Potosí; J. Sibilia, MD, Service de Rhumatologie, CHU de Strasbourg, Hôpital de Hautepierre; J-C. Becker, MD, Bristol-Myers Squibb*; R. Westhovens, MD, Department of Rheumatology, Universitaire Ziekenhuizenn Leuven; H.K. Genant, MD, UCSF/Synarc.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.130263
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http://dx.doi.org/10.3899/jrheum.130263DOI Listing
June 2014

"Design characteristics of the CORRONA CERTAIN study: a comparative effectiveness study of biologic agents for rheumatoid arthritis patients".

BMC Musculoskelet Disord 2014 Apr 1;15:113. Epub 2014 Apr 1.

Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294-7201, USA.

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http://dx.doi.org/10.1186/1471-2474-15-113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978136PMC
April 2014

Comparative cancer risk associated with methotrexate, other non-biologic and biologic disease-modifying anti-rheumatic drugs.

Semin Arthritis Rheum 2014 Feb 5;43(4):489-97. Epub 2013 Sep 5.

Clinical Trials Unit, Division of Rheumatology, New York University School of Medicine, New York, NY.

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http://dx.doi.org/10.1016/j.semarthrit.2013.08.003DOI Listing
February 2014

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

Nature 2014 Feb 25;506(7488):376-81. Epub 2013 Dec 25.

1] Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature12873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944098PMC
February 2014

Applying biologic therapies to the management of patients with rheumatoid arthritis.

Semin Arthritis Rheum 2014 Feb 14;43(4):577. Epub 2013 Dec 14.

Arthritis and Rheumatism Associates, Rockville, MD.

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http://dx.doi.org/10.1016/j.semarthrit.2013.12.004DOI Listing
February 2014

Rheumatoid arthritis: New EULAR guidelines for RA: a job well done.

Authors:
Joel M Kremer

Nat Rev Rheumatol 2014 Jan 3;10(1):6-8. Epub 2013 Dec 3.

Albany Medical College, The Centre for Rheumatology, 1367 Washington Avenue, Albany, NY 12206, USA.

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http://dx.doi.org/10.1038/nrrheum.2013.188DOI Listing
January 2014

Proceedings of the 5th annual perspectives in rheumatic diseases.

Semin Arthritis Rheum 2013 Dec;43(3):416-9

UCLA Rheumatology, 1000 Veteran Ave, Room 32-59 Rehab, Los Angeles, CA 90095. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2013.06.002DOI Listing
December 2013

Pure ocular mucous membrane pemphigoid in a patient with axial spondyloarthritis (HLA-B27 positive).

Rheumatology (Oxford) 2013 Nov 24;52(11):2097-9. Epub 2013 Apr 24.

Stratton VA Medical Center, 113 Holland Avenue, MC 111, Albany, NY 12208, USA.

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http://dx.doi.org/10.1093/rheumatology/ket157DOI Listing
November 2013

Comorbidities are associated with poorer outcomes in community patients with rheumatoid arthritis.

Rheumatology (Oxford) 2013 Oct 27;52(10):1809-17. Epub 2013 Jun 27.

University of California at Los Angeles, 1000 Veteran Avenue, Rehab Building 32-59, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/rheumatology/ket224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775293PMC
October 2013

Methotrexate polyglutamation in relation to infliximab pharmacokinetics in rheumatoid arthritis.

Ann Rheum Dis 2013 Jun 17;72(6):908-10. Epub 2012 Nov 17.

R&D Department, Exagen Diagnostics, Vista, California 92081, USA.

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http://dx.doi.org/10.1136/annrheumdis-2012-202591DOI Listing
June 2013

Change: embrace it or move over.

Authors:
Joel M Kremer

Curr Opin Rheumatol 2013 May;25(3):285-6

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http://dx.doi.org/10.1097/BOR.0b013e32835fd96cDOI Listing
May 2013

Association of rheumatoid arthritis risk alleles with response to anti-TNF biologics: results from the CORRONA registry and meta-analysis.

Inflammation 2013 Apr;36(2):279-84

Division of Rheumatology, Department of Medicine, New York Presbyterian Hospital, College of Physicians and Surgeons, Columbia University, P&S Building, Suite 10-455, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s10753-012-9544-4DOI Listing
April 2013

Comparative effectiveness of nonbiologic versus biologic disease-modifying antirheumatic drugs for rheumatoid arthritis.

J Rheumatol 2013 Feb 15;40(2):127-36. Epub 2013 Jan 15.

Division of Rheumatology, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.3899/jrheum.120400DOI Listing
February 2013

Smoking, smoking cessation, and disease activity in a large cohort of patients with rheumatoid arthritis.

J Rheumatol 2012 May 15;39(5):904-9. Epub 2012 Mar 15.

Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.3899/jrheum.110852DOI Listing
May 2012