Publications by authors named "Joel Dudley"

100Publications

Deep representation learning of electronic health records to unlock patient stratification at scale.

NPJ Digit Med 2020 17;3:96. Epub 2020 Jul 17.

Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY USA.

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http://dx.doi.org/10.1038/s41746-020-0301-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367859PMC
July 2020

miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.

Acta Neuropathol 2020 Sep 14;140(3):295-315. Epub 2020 Jul 14.

Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s00401-020-02185-zDOI Listing
September 2020

Identification of therapeutic targets from genetic association studies using hierarchical component analysis.

BioData Min 2020 17;13. Epub 2020 Jun 17.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.

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http://dx.doi.org/10.1186/s13040-020-00216-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301559PMC
June 2020

Sleep in the Natural Environment: A Pilot Study.

Sensors (Basel) 2020 Mar 3;20(5). Epub 2020 Mar 3.

Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10032, USA.

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http://dx.doi.org/10.3390/s20051378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085707PMC
March 2020

Identifying Acute Low Back Pain Episodes in Primary Care Practice From Clinical Notes: Observational Study.

JMIR Med Inform 2020 Feb 27;8(2):e16878. Epub 2020 Feb 27.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.2196/16878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068466PMC
February 2020

Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin.

Oncotarget 2020 Jan 28;11(4):409-418. Epub 2020 Jan 28.

Feinberg School of Medicine, Department of Dermatology, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.18632/oncotarget.27445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996908PMC
January 2020

MEWS++: Enhancing the Prediction of Clinical Deterioration in Admitted Patients through a Machine Learning Model.

J Clin Med 2020 Jan 27;9(2). Epub 2020 Jan 27.

Institute for Healthcare Delivery Science, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.3390/jcm9020343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073544PMC
January 2020

Clarifying the Potential Role of Microbes in Alzheimer's Disease.

Neuron 2019 12;104(6):1036-1037

Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ 85287-5001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.11.008DOI Listing
December 2019

Scaling structural learning with NO-BEARS to infer causal transcriptome networks.

Pac Symp Biocomput 2020 ;25:391-402

Institute for Next Generation Healthcare, USA.

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January 2020

Automated phenotyping of patients with non-alcoholic fatty liver disease reveals clinically relevant disease subtypes.

Pac Symp Biocomput 2020 ;25:91-102

Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043281PMC
January 2020

Early life stress alters transcriptomic patterning across reward circuitry in male and female mice.

Nat Commun 2019 11 8;10(1):5098. Epub 2019 Nov 8.

Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41467-019-13085-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841985PMC
November 2019

Building a Secure Biomedical Data Sharing Decentralized App (DApp): Tutorial.

J Med Internet Res 2019 10 23;21(10):e13601. Epub 2019 Oct 23.

Center for Biomedical Blockchain Research, Icahn School of Medicine at Mount Sinai, Redwood City, CA, United States.

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http://dx.doi.org/10.2196/13601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835476PMC
October 2019

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.

Nat Commun 2019 08 23;10(1):3834. Epub 2019 Aug 23.

Department of Psychiatry, Pamela Sklar Division of Psychiatric Genomics and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41467-019-11874-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707297PMC
August 2019

Privacy-Preserving Methods for Feature Engineering Using Blockchain: Review, Evaluation, and Proof of Concept.

J Med Internet Res 2019 08 14;21(8):e13600. Epub 2019 Aug 14.

Center for Biomedical Blockchain Research, Icahn School of Medicine at Mount Sinai, Redwood City, CA, United States.

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http://dx.doi.org/10.2196/13600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712958PMC
August 2019

Reflecting health: smart mirrors for personalized medicine.

NPJ Digit Med 2018 8;1:62. Epub 2018 Nov 8.

1Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY USA.

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http://dx.doi.org/10.1038/s41746-018-0068-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550276PMC
November 2018

Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans.

BMC Genet 2019 07 2;20(1):52. Epub 2019 Jul 2.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1186/s12863-019-0758-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604157PMC
July 2019

Transcriptomic Network Interactions in Human Skin Treated with Topical Glucocorticoid Clobetasol Propionate.

J Invest Dermatol 2019 11 25;139(11):2281-2291. Epub 2019 Jun 25.

Department of Dermatology, Northwestern University, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814545PMC
November 2019

Natural Language Processing of Clinical Notes on Chronic Diseases: Systematic Review.

JMIR Med Inform 2019 Apr 27;7(2):e12239. Epub 2019 Apr 27.

eHealth Research Group, Fondazione Bruno Kessler Research Institute, Trento, Italy.

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http://medinform.jmir.org/2019/2/e12239/
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http://dx.doi.org/10.2196/12239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528438PMC
April 2019

Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy.

Circ Genom Precis Med 2019 06 6;12(6):e002390. Epub 2019 May 6.

Department of Genetics and Genomic Sciences (I.F., B.R., L.A., S.K., J.T.D., C.G., J.L.M.B., I.P.), Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1161/CIRCGEN.118.002390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601350PMC
June 2019

Designing Robust N-of-1 Studies for Precision Medicine: Simulation Study and Design Recommendations.

J Med Internet Res 2019 04 1;21(4):e12641. Epub 2019 Apr 1.

Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.2196/12641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462889PMC
April 2019

Lyme Disease Patient Trajectories Learned from Electronic Medical Data for Stratification of Disease Risk and Therapeutic Response.

Sci Rep 2019 03 14;9(1):4460. Epub 2019 Mar 14.

Department of Genetics and Genomic Sciences, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1498, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41598-019-41128-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418311PMC
March 2019

Evaluation of patient re-identification using laboratory test orders and mitigation via latent space variables.

Pac Symp Biocomput 2019 ;24:415-426

Institute for Next Generation Healthcare, Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave 15th Fl., New York, NY 10065, USA*Authors contributed equally.

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February 2020

Predicting Future Cardiovascular Events in Patients With Peripheral Artery Disease Using Electronic Health Record Data.

Circ Cardiovasc Qual Outcomes 2019 03;12(3):e004741

Center for Biomedical Informatics Research (K.J., N.H.S., E.G.R), Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415677PMC
March 2019

Leveraging Big Data to Transform Drug Discovery.

Methods Mol Biol 2019 ;1939:91-118

Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9089-4_6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657335PMC
July 2019

PI3K inhibitors protect against glucocorticoid-induced skin atrophy.

EBioMedicine 2019 Mar 5;41:526-537. Epub 2019 Feb 5.

Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441871PMC
March 2019

Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder.

Schizophr Res 2019 05 12;207:12-21. Epub 2018 Nov 12.

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964183062
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http://dx.doi.org/10.1016/j.schres.2018.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591017PMC
May 2019

The whole is greater than the sum of its parts: combining classical statistical and machine intelligence methods in medicine.

Heart 2018 07;104(14):1228

Division of Cardiology, West Virginia Heart and Vascular Institute, Morgantown, West Virginia, USA.

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http://dx.doi.org/10.1136/heartjnl-2018-313377DOI Listing
July 2018

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

Neuron 2018 07 21;99(1):64-82.e7. Epub 2018 Jun 21.

Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ 85287-5001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551233PMC
July 2018

A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report.

Cureus 2018 Apr 9;10(4):e2452. Epub 2018 Apr 9.

Icahn Institute, Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.7759/cureus.2452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991918PMC
April 2018

Artificial Intelligence in Cardiology.

J Am Coll Cardiol 2018 06;71(23):2668-2679

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.03.521DOI Listing
June 2018

The Rapid Prediction of Carbapenem Resistance in Patients With Bacteremia Using Electronic Medical Record Data.

Open Forum Infect Dis 2018 May 28;5(5):ofy091. Epub 2018 Apr 28.

Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1093/ofid/ofy091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961319PMC
May 2018

Adaptive Landscape of Protein Variation in Human Exomes.

Mol Biol Evol 2018 08;35(8):2015-2025

Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.

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http://dx.doi.org/10.1093/molbev/msy107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063297PMC
August 2018

Disease Heritability Inferred from Familial Relationships Reported in Medical Records.

Cell 2018 06 17;173(7):1692-1704.e11. Epub 2018 May 17.

Department of Biomedical Informatics, Columbia University, New York, NY, USA; Institute for Genomic Medicine, Columbia University, New York, NY, USA; Observational Health Data Sciences and Informatics (OHDSI), New York, NY, USA; Department of Medicine, Columbia University, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Data Science Institute, Columbia University, New York, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183052
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http://dx.doi.org/10.1016/j.cell.2018.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015747PMC
June 2018

The next generation of precision medicine: observational studies, electronic health records, biobanks and continuous monitoring.

Hum Mol Genet 2018 05;27(R1):R56-R62

Institute for Next Generation Healthcare Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, NY 10029, USA.

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https://academic.oup.com/hmg/article/27/R1/R56/4969371
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http://dx.doi.org/10.1093/hmg/ddy114DOI Listing
May 2018

Isolation and Identification of the Follicular Microbiome: Implications for Acne Research.

J Invest Dermatol 2018 09 13;138(9):2033-2040. Epub 2018 Mar 13.

Department of Dermatology, Penn State College of Medicine, Hershey, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.02.038DOI Listing
September 2018

Machine learning in cardiovascular medicine: are we there yet?

Heart 2018 07 19;104(14):1156-1164. Epub 2018 Jan 19.

Division of Cardiology, West Virginia Heart and Vascular Institute, Morgantown, West Virginia, USA.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2017-311198
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http://dx.doi.org/10.1136/heartjnl-2017-311198DOI Listing
July 2018

Causal inference on electronic health records to assess blood pressure treatment targets: an application of the parametric g formula.

Pac Symp Biocomput 2018 ;23:180-191

Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10065, US.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728675PMC
August 2018

Automated disease cohort selection using word embeddings from Electronic Health Records.

Pac Symp Biocomput 2018 ;23:145-156

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York, NY 10065, USA, ²Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York, NY 10065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788312PMC
August 2018

Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders.

Pac Symp Biocomput 2018 ;23:68-79

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ²Departments of Psychiatry and Opthamology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ³Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁴Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁵Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁶Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728668PMC
August 2018

Cell-specific prediction and application of drug-induced gene expression profiles.

Pac Symp Biocomput 2018 ;23:32-43

Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, 10065; New York, USA, ²Department of Genetics and Genomic Sciences, ISMMS, New York, NY, 10029; New York, USA, ³Courant Institute of Mathematical Sciences, New York University, New York, NY, 10012; New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753597PMC
August 2018

Regulatory T-cell Genes Drive Altered Immune Microenvironment in Adult Solid Cancers and Allow for Immune Contextual Patient Subtyping.

Cancer Epidemiol Biomarkers Prev 2018 01 13;27(1):103-112. Epub 2017 Nov 13.

Roche Pharma Research and Early Development - Operations, Roche Innovation Center, New York, New York.

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http://cebp.aacrjournals.org/lookup/doi/10.1158/1055-9965.EP
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http://dx.doi.org/10.1158/1055-9965.EPI-17-0461DOI Listing
January 2018

Predicting age by mining electronic medical records with deep learning characterizes differences between chronological and physiological age.

J Biomed Inform 2017 Dec 4;76:59-68. Epub 2017 Nov 4.

Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15320464173024
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http://dx.doi.org/10.1016/j.jbi.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716867PMC
December 2017

Necroptosis activation in Alzheimer's disease.

Nat Neurosci 2017 Sep 24;20(9):1236-1246. Epub 2017 Jul 24.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1038/nn.4608DOI Listing
September 2017

Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine.

JACC Basic Transl Sci 2017 Jun 26;2(3):311-327. Epub 2017 Jun 26.

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York.

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http://dx.doi.org/10.1016/j.jacbts.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034501PMC
June 2017

Deep learning for healthcare: review, opportunities and challenges.

Brief Bioinform 2018 11;19(6):1236-1246

the Institute for Next Generation Healthcare and associate professor in the Department of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1093/bib/bbx044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455466PMC
November 2018

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells.

Sci Rep 2017 03 3;7:42563. Epub 2017 Mar 3.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1038/srep42563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335661PMC
March 2017

Accelerators: Sparking Innovation and Transdisciplinary Team Science in Disparities Research.

Int J Environ Res Public Health 2017 02 23;14(3). Epub 2017 Feb 23.

Center for Health Equity and Community Engaged Research, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.3390/ijerph14030225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369061PMC
February 2017

Automated cell type discovery and classification through knowledge transfer.

Bioinformatics 2017 Jun;33(11):1689-1695

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447237PMC
June 2017

High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.

PLoS Genet 2017 01 27;13(1):e1006565. Epub 2017 Jan 27.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271178PMC
January 2017

Integrative Analysis of Disease Signatures Shows Inflammation Disrupts Juvenile Experience-Dependent Cortical Plasticity.

eNeuro 2016 Nov-Dec;3(6). Epub 2017 Jan 18.

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York 10029; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.

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http://eneuro.org/cgi/doi/10.1523/ENEURO.0240-16.2016
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http://dx.doi.org/10.1523/ENEURO.0240-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241709PMC
October 2017

Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach.

Sci Rep 2017 01 4;7:39487. Epub 2017 Jan 4.

Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1038/srep39487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209709PMC
January 2017

EXPLORING THE REPRODUCIBILITY OF PROBABILISTIC CAUSAL MOLECULAR NETWORK MODELS.

Pac Symp Biocomput 2017 ;22:120-131

Icahn Institute and Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1498, New York, NY, 10029, USA*Co-first Authors.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161348PMC
http://dx.doi.org/10.1142/9789813207813_0013DOI Listing
July 2017

Machine-Learning Algorithms to Automate Morphological and Functional Assessments in 2D Echocardiography.

J Am Coll Cardiol 2016 11;68(21):2287-2295

Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.08.062DOI Listing
November 2016

e-GRASP: an integrated evolutionary and GRASP resource for exploring disease associations.

BMC Genomics 2016 10 17;17(Suppl 9):770. Epub 2016 Oct 17.

Center for Excellence in Genome Medicine and Research, King Abdulaziz University, Jeddah, Saudi Arabia.

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http://dx.doi.org/10.1186/s12864-016-3088-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073857PMC
October 2016

Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth.

ACS Nano 2016 12 19;10(12):10636-10651. Epub 2016 Oct 19.

Institute of Next Generation Healthcare, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System , New York, New York 10029, United States.

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http://dx.doi.org/10.1021/acsnano.6b02231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939886PMC
December 2016