Joel Beaudouin

Joel Beaudouin

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Joel Beaudouin

Joel Beaudouin

Publications by authors named "Joel Beaudouin"

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23Publications

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3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival.

Cell Rep 2019 Nov;29(8):2295-2306.e6

Department of Molecular Neurobiology, German Cancer Research Center (DFKZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.054DOI Listing
November 2019

Single-Fluorescent Protein Reporters Allow Parallel Quantification of Natural Killer Cell-Mediated Granzyme and Caspase Activities in Single Target Cells.

Front Immunol 2018 8;9:1840. Epub 2018 Aug 8.

Department for Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), Dortmund, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.01840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092488PMC
September 2019

NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing.

J Exp Med 2019 Sep 3;216(9):2113-2127. Epub 2019 Jul 3.

Department for Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund, Dortmund, Germany

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http://dx.doi.org/10.1084/jem.20181454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719417PMC
September 2019

Quantitative Single-Molecule Localization Microscopy (qSMLM) of Membrane Proteins Based on Kinetic Analysis of Fluorophore Blinking Cycles.

Methods Mol Biol 2017 ;1663:115-126

Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, Max-von-Laue-Str. 7, Frankfurt am Main, 60438, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7265-4_10DOI Listing
May 2018

Automated Analysis of Single-Molecule Photobleaching Data by Statistical Modeling of Spot Populations.

Biophys J 2015 Dec;109(11):2352-62

Division of Theoretical Bioinformatics (B080), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2015.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675885PMC
December 2015

One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy.

Sci Rep 2015 Sep 11;5:14072. Epub 2015 Sep 11.

Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1038/srep14072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642553PMC
September 2015

Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis.

Sci Signal 2014 Mar 11;7(316):ra23. Epub 2014 Mar 11.

1Department for Bioinformatics and Functional Genomics, Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1126/scisignal.2004738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208692PMC
March 2014

Multiparametric image analysis reveals role of Caveolin1 in endosomal progression rather than internalization of EGFR.

FEBS Lett 2012 Apr 1;586(8):1179-89. Epub 2012 Mar 1.

Theoretical Bioinformatics, German Cancer Research Center, 69120 Heidelberg, Germany.

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http://doi.wiley.com/10.1016/j.febslet.2012.02.041
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http://dx.doi.org/10.1016/j.febslet.2012.02.041DOI Listing
April 2012

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.

Mol Syst Biol 2010 9;6:352. Epub 2010 Mar 9.

Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/msb.2010.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858442PMC
August 2010

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.

J Cell Biol 2010 Aug;190(3):377-89

Division of Immunogenetics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1083/jcb.201002060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922645PMC
August 2010

Live cell dynamics of promyelocytic leukemia nuclear bodies upon entry into and exit from mitosis.

Mol Biol Cell 2008 Jul 14;19(7):3147-62. Epub 2008 May 14.

Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1091/mbc.e08-01-0035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441680PMC
July 2008

Tropical--parameter estimation and simulation of reaction-diffusion models based on spatio-temporal microscopy images.

Bioinformatics 2006 Nov 29;22(21):2709-10. Epub 2006 Aug 29.

Department of Theoretical Bioinformatics, German Cancer Research Center Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btl456DOI Listing
November 2006

Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins.

Biophys J 2006 Mar 30;90(6):1878-94. Epub 2005 Dec 30.

Gene Expression and Cell Biology/Biophysics Programs, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1529/biophysj.105.071241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386769PMC
March 2006

Calcium rises locally trigger focal adhesion disassembly and enhance residency of focal adhesion kinase at focal adhesions.

J Biol Chem 2004 Jul 21;279(27):28715-23. Epub 2004 Apr 21.

Laboratoire de Pharmacologie et Physicochimie des Interactions Cellulaires et Moléculaires, Unité Mixte de Recherche CNRS 7034, Université Louis Pasteur de Strasbourg, 67401 Illkirch, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M404054200
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http://dx.doi.org/10.1074/jbc.M404054200DOI Listing
July 2004

NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization.

J Cell Biol 2003 Sep 8;162(6):1017-29. Epub 2003 Sep 8.

Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1083/jcb.200302129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172854PMC
September 2003

Global chromosome positions are transmitted through mitosis in mammalian cells.

Cell 2003 Mar;112(6):751-64

Intelligent Bioinformatics Systems, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/s0092-8674(03)00189-2DOI Listing
March 2003

Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p.

J Cell Biol 2002 Dec 23;159(6):971-82. Epub 2002 Dec 23.

Zentrum für Molekulare Biologie, Universität Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1083/jcb.200207101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173977PMC
December 2002

Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina.

Cell 2002 Jan;108(1):83-96

Gene Expression and Cell Biology/Biophysics Programmes, European Molecular Biology Laboratory, D-69117. Heidelberg, Germany

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http://dx.doi.org/10.1016/s0092-8674(01)00627-4DOI Listing
January 2002