Joe W Gray

Joe W Gray

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Cyclic Multiplexed-Immunofluorescence (cmIF), a Highly Multiplexed Method for Single-Cell Analysis.

Methods Mol Biol 2020 ;2055:521-562

Department of Biomedical Engineering and OHSU Center for Spatial Systems Biomedicine, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.1007/978-1-4939-9773-2_24DOI Listing
January 2020

PLK1 and EGFR targeted nanoparticle as a radiation sensitizer for non-small cell lung cancer.

Cancer Lett 2019 Dec 26;467:9-18. Epub 2019 Sep 26.

Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, 97239, USA; PDX Pharmaceuticals, LLC, Portland, OR, 97239, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927399PMC
December 2019

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters.

Cell Rep 2019 Dec;29(11):3448-3459.e6

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948147PMC
December 2019

High-throughput single-particle tracking reveals nested membrane domains that dictate KRas diffusion and trafficking.

Elife 2019 Nov 1;8. Epub 2019 Nov 1.

Department of Biomedical Engineering, Oregon Health and Science University, Portland, United States.

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http://dx.doi.org/10.7554/eLife.46393DOI Listing
November 2019

Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer.

J Vis Exp 2019 05 21(147). Epub 2019 May 21.

Department of Biomedical Engineering, Knight Cancer Institute, Oregon Health and Science University;

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http://dx.doi.org/10.3791/58957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736605PMC
May 2019

Therapeutic Clues from an Integrated Omic Assessment of East Asian Triple Negative Breast Cancers.

Cancer Cell 2019 03;35(3):341-343

Center for Spatial Systems Biomedicine, Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR 97201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499473PMC
March 2019

Variational Autoencoding Tissue Response to Microenvironment Perturbation.

Proc SPIE Int Soc Opt Eng 2019 Feb 15;10949. Epub 2019 Mar 15.

Dept. of Biomedical Engineering, Center for Spatial Systems Biomedicine, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1117/12.2512660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677277PMC
February 2019

Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment.

PLoS One 2018 7;13(6):e0198141. Epub 2018 Jun 7.

Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198141PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991725PMC
January 2019

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes.

Cell Syst 2018 Mar 14;6(3):329-342.e6. Epub 2018 Mar 14.

Department of Biomedical Engineering, Knight Cancer Institute, OHSU Center for Spatial Systems Biomedicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24054712183005
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http://dx.doi.org/10.1016/j.cels.2018.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927625PMC
March 2018

A fully integrated, three-dimensional fluorescence to electron microscopy correlative workflow.

Methods Cell Biol 2017 19;140:149-164. Epub 2017 Apr 19.

Oregon Health and Sciences University, Portland, OR, United States.

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http://dx.doi.org/10.1016/bs.mcb.2017.03.008DOI Listing
February 2018

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Authors:
Alexandra B Keenan Sherry L Jenkins Kathleen M Jagodnik Simon Koplev Edward He Denis Torre Zichen Wang Anders B Dohlman Moshe C Silverstein Alexander Lachmann Maxim V Kuleshov Avi Ma'ayan Vasileios Stathias Raymond Terryn Daniel Cooper Michele Forlin Amar Koleti Dusica Vidovic Caty Chung Stephan C Schürer Jouzas Vasiliauskas Marcin Pilarczyk Behrouz Shamsaei Mehdi Fazel Yan Ren Wen Niu Nicholas A Clark Shana White Naim Mahi Lixia Zhang Michal Kouril John F Reichard Siva Sivaganesan Mario Medvedovic Jaroslaw Meller Rick J Koch Marc R Birtwistle Ravi Iyengar Eric A Sobie Evren U Azeloglu Julia Kaye Jeannette Osterloh Kelly Haston Jaslin Kalra Steve Finkbiener Jonathan Li Pamela Milani Miriam Adam Renan Escalante-Chong Karen Sachs Alex Lenail Divya Ramamoorthy Ernest Fraenkel Gavin Daigle Uzma Hussain Alyssa Coye Jeffrey Rothstein Dhruv Sareen Loren Ornelas Maria Banuelos Berhan Mandefro Ritchie Ho Clive N Svendsen Ryan G Lim Jennifer Stocksdale Malcolm S Casale Terri G Thompson Jie Wu Leslie M Thompson Victoria Dardov Vidya Venkatraman Andrea Matlock Jennifer E Van Eyk Jacob D Jaffe Malvina Papanastasiou Aravind Subramanian Todd R Golub Sean D Erickson Mohammad Fallahi-Sichani Marc Hafner Nathanael S Gray Jia-Ren Lin Caitlin E Mills Jeremy L Muhlich Mario Niepel Caroline E Shamu Elizabeth H Williams David Wrobel Peter K Sorger Laura M Heiser Joe W Gray James E Korkola Gordon B Mills Mark LaBarge Heidi S Feiler Mark A Dane Elmar Bucher Michel Nederlof Damir Sudar Sean Gross David F Kilburn Rebecca Smith Kaylyn Devlin Ron Margolis Leslie Derr Albert Lee Ajay Pillai

Cell Syst 2018 01 29;6(1):13-24. Epub 2017 Nov 29.

NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.cels.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799026PMC
January 2018

Simultaneous Multicolor Single-Molecule Tracking with Single-Laser Excitation via Spectral Imaging.

Biophys J 2018 01;114(2):301-310

Department of Biomedical Engineering, OHSU Center for Spatial Systems Biomedicine, and Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984991PMC
January 2018

Pathway-Enriched Gene Signature Associated with 53BP1 Response to PARP Inhibition in Triple-Negative Breast Cancer.

Mol Cancer Ther 2017 Dec 27;16(12):2892-2901. Epub 2017 Sep 27.

Department of Biomedical Engineering, OHSU Center for Spatial Systems Biomedicine, Oregon Health and Science University, Portland, Oregon.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-17-0170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765867PMC
December 2017

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics.

Sci Data 2017 11 7;4:170166. Epub 2017 Nov 7.

HMS LINCS Center, Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA 02115 USA.

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http://dx.doi.org/10.1038/sdata.2017.166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674849PMC
November 2017

Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution.

Sci Rep 2017 11 28;7(1):16459. Epub 2017 Nov 28.

Department of Biomedical Engineering, OHSU Center for Spatial Systems Biomedicine, Oregon Health & Science University, 2730 SW Moody Ave, Portland, OR, 97201, USA.

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http://dx.doi.org/10.1038/s41598-017-16492-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705767PMC
November 2017

Reconstruction of Gene Regulatory Networks based on Repairing Sparse Low-rank Matrices.

IEEE/ACM Trans Comput Biol Bioinform 2016 Jul-Aug;13(4):767-777. Epub 2015 Aug 7.

Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94720 USA; Faculty Scientist, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA.

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http://dx.doi.org/10.1109/TCBB.2015.2465952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154690PMC
September 2017

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy.

PLoS One 2017 31;12(5):e0176839. Epub 2017 May 31.

Department of Biomedical Engineering, Knight Cancer Institute, and OHSU Center for Spatial Systems Biomedicine (OCSSB), Oregon Health and Science University, Portland, Oregon, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176839PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451012PMC
September 2017

Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells.

Cancer Res 2017 04 13;77(7):1575-1585. Epub 2017 Jan 13.

Divisions of Gastroenterology and Hematology/Oncology, Department of Medicine, University of California, San Francisco, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410377PMC
April 2017

Targeted Treatment of Metastatic Breast Cancer by PLK1 siRNA Delivered by an Antioxidant Nanoparticle Platform.

Mol Cancer Ther 2017 04 30;16(4):763-772. Epub 2017 Jan 30.

Department of Biomedical Engineering, Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445934PMC
April 2017

Integrative Analysis on Histopathological Image for Identifying Cellular Heterogeneity.

Proc SPIE Int Soc Opt Eng 2017 Feb 1;10140. Epub 2017 Mar 1.

Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.1117/12.2250428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198666PMC
February 2017

Epigenomic Inactivation of RasGAPs Activates RAS Signaling in a Subset of Luminal B Breast Cancers.

Cancer Discov 2017 02;7(2):131-133

Department of Biomedical Engineering, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1158/2159-8290.CD-16-1423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312830PMC
February 2017

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.

Breast Cancer Res Treat 2017 01 26;161(1):17-28. Epub 2016 Oct 26.

Department of Surgery, University of California, 2340 Sutter St, N321, San Francisco, CA, 94115, USA.

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http://dx.doi.org/10.1007/s10549-016-4036-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225037PMC
January 2017

PI3 Kinase Pathway Mutations in Human Cancers.

Authors:
Joe W Gray

JAMA Oncol 2016 Dec;2(12):1543-1544

Department of Biomedical Engineering, Center for Spatial Systems Biomedicine, Knight Cancer Institute, Oregon Health and Science University, Portland.

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http://dx.doi.org/10.1001/jamaoncol.2016.0875DOI Listing
December 2016

Multiplexed imaging reveals heterogeneity of PI3K/MAPK network signaling in breast lesions of known PIK3CA genotype.

Breast Cancer Res Treat 2016 Oct 31;159(3):575-83. Epub 2016 Aug 31.

Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, 97201, USA.

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http://dx.doi.org/10.1007/s10549-016-3962-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762199PMC
October 2016

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer.

Proc Natl Acad Sci U S A 2016 10 6;113(43):E6600-E6609. Epub 2016 Oct 6.

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Department of Medicine, Baylor College of Medicine, Houston, TX 77030;

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http://dx.doi.org/10.1073/pnas.1612835113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087040PMC
October 2016

Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death.

Oncotarget 2016 Jun;7(24):36138-36153

Department of Pathology and Laboratory Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.18632/oncotarget.9147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094989PMC
June 2016

Disentangling multidimensional spatio-temporal data into their common and aberrant responses.

PLoS One 2015 22;10(4):e0121607. Epub 2015 Apr 22.

Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA; Faculty Scientist, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121607PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406848PMC
April 2016

Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment.

Cancer Treat Rev 2016 Apr 22;45:19-29. Epub 2016 Feb 22.

Department of Biomedical Engineering, Oregon Health and Science University, 3303 SW Bond Ave, Portland, OR 97239, USA; PDX Pharmaceuticals, LLC, 3303 SW Bond Ave, Portland, OR 97239, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2016.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826844PMC
April 2016

Therapeutic siRNA for drug-resistant HER2-positive breast cancer.

Oncotarget 2016 Mar;7(12):14727-41

Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, 97239, USA.

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http://dx.doi.org/10.18632/oncotarget.7409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924747PMC
March 2016

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics.

Mol Cancer Res 2016 Jan 6;14(1):3-13. Epub 2015 Aug 6.

Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, Colorado. University of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828339PMC
January 2016

Large-Scale Drug Screens Support Precision Medicine.

Cancer Discov 2015 Nov;5(11):1130-2

The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633700PMC
November 2015

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway.

Proc Natl Acad Sci U S A 2015 Jun 16;112(26):7996-8001. Epub 2015 Jun 16.

Departments of Physics and Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1509123112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491781PMC
June 2015

Do breast cancer cell lines provide a relevant model of the patient tumor methylome?

PLoS One 2014 26;9(8):e105545. Epub 2014 Aug 26.

Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105545PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144876PMC
May 2015

Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections.

Theranostics 2014 11;4(9):872-92. Epub 2014 Jun 11.

1. Zhejiang-California International Nanosystems Institute, Zhejiang University, Hangzhou, Zhejiang 310029, China ; 3. Life Sciences College, Fudan University, Shanghai 200433, China ; 4. Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94127, USA.

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http://dx.doi.org/10.7150/thno.9404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107289PMC
April 2015

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications.

Cell Cycle 2014 9;13(3):353-7. Epub 2014 Jan 9.

Laboratory for Experimental Oncology and Radiobiology; Center for Experimental Molecular Medicine; Academic Medical Center (AMC); Amsterdam, The Netherlands.

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http://dx.doi.org/10.4161/cc.27769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956531PMC
January 2015

Exact reconstruction of gene regulatory networks using compressive sensing.

BMC Bioinformatics 2014 Dec 14;15:400. Epub 2014 Dec 14.

Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, 94720, CA, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12859-014-0400-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308013PMC
December 2014

Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells.

Eur J Cancer 2014 Nov 15;50(16):2877-86. Epub 2014 Sep 15.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC 20057, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2014.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210771PMC
November 2014

Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers.

J Cell Sci 2014 Nov 12;127(Pt 22):4894-903. Epub 2014 Sep 12.

California Pacific Medical Center Research Institute, 475 Brannan St., Suite 220, San Francisco, CA 94107, USA Biomedical Engineering Department, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA

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http://dx.doi.org/10.1242/jcs.152728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231305PMC
November 2014

Causal network inference using biochemical kinetics.

Bioinformatics 2014 Sep;30(17):i468-74

Department of Statistics, University of Warwick, Coventry, CV4 7AL, MRC Biostatistics Unit, Cambridge, CB2 0SR, UK, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94710, Department of Biomedical Engineering, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239-3098, USA and School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, UK Department of Statistics, University of Warwick, Coventry, CV4 7AL, MRC Biostatistics Unit, Cambridge, CB2 0SR, UK, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94710, Department of Biomedical Engineering, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239-3098, USA and School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, UK.

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http://dx.doi.org/10.1093/bioinformatics/btu452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147905PMC
September 2014

A robust prognostic signature for hormone-positive node-negative breast cancer.

Genome Med 2013 11;5(10):92. Epub 2013 Oct 11.

Department of Cancer and DNA Damage Responses, Life Sciences Division, Lawrence Berkeley National Laboratory, One Cyclotron Rd, Berkeley 94720, CA, USA ; Department of Biomedical Engineering, Center for Spatial Systems Biomedicine, Knight Cancer Institute, Oregon Health and Science University, 3303 SW Bond Ave, Portland, 97239, OR, USA.

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http://dx.doi.org/10.1186/gm496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961800PMC
May 2014

Detecting cancer by monitoring circulating tumor DNA.

Nat Med 2014 May;20(5):474-5

Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon, USA.

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http://dx.doi.org/10.1038/nm.3564DOI Listing
May 2014

CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression.

Cancer Res 2014 Jan 4;74(2):520-31. Epub 2013 Dec 4.

Authors' Affiliations: Department of Human Anatomy and Key Laboratory of Experimental Teratology, Ministry of Education; Department of Biochemistry and Molecular Biology, Shandong University School of Medicine; Department of Respiratory Medicine, Qilu Hospital, Shandong University, Jinan; International Biotechnology R&D Center, Shandong University School of Ocean, Weihai, Shandong, China; Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley; Department of Pathology; Thoracic Oncology Laboratory, Department of Surgery; Helen Diller Family Comprehensive Cancer Center and Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California; and Department of Biomedical Engineering, Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934357PMC
January 2014

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges.

Nat Struct Mol Biol 2013 Dec 10;20(12):1434-42. Epub 2013 Nov 10.

1] Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [2] Stem Cell Program, University of California, San Diego, La Jolla, California, USA. [3] Institute for Genomic Medicine, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nsmb.2699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918504PMC
December 2013

Metrics other than potency reveal systematic variation in responses to cancer drugs.

Nat Chem Biol 2013 Nov 8;9(11):708-14. Epub 2013 Sep 8.

Harvard Medical School Library of Integrated Network-based Cellular Signatures Center, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nchembio.1337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947796PMC
November 2013

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling.

Proc Natl Acad Sci U S A 2013 Nov 24;110(46):18519-24. Epub 2013 Oct 24.

California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720.

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http://dx.doi.org/10.1073/pnas.1318188110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831949PMC
November 2013

Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.

Cancer Cell 2013 Oct 3;24(4):450-65. Epub 2013 Oct 3.

UCSF/Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931310PMC
October 2013

c-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells.

Cancer Res 2013 Jul 23;73(14):4510-20. Epub 2013 May 23.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715569PMC
July 2013

Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association.

IEEE Trans Med Imaging 2013 Apr 4;32(4):670-82. Epub 2012 Dec 4.

Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1109/TMI.2012.2231420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728287PMC
April 2013

Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays.

Microarrays (Basel) 2013 Apr 11;2(2):97-114. Epub 2013 Apr 11.

Department of Biomedical Engineering and Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.3390/microarrays2020097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003478PMC
April 2013

Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer.

Cancer Res 2013 Apr 11;73(7):2070-81. Epub 2013 Feb 11.

Department of Pharmaceutical Chemistry, UCSF Helen Diller Family Comprehensive Cancer Research Center, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618559PMC
April 2013

Bayesian inference of signaling network topology in a cancer cell line.

Bioinformatics 2012 Nov 24;28(21):2804-10. Epub 2012 Aug 24.

Department of Biochemistry, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/bts514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476330PMC
November 2012

What are we learning from the cancer genome?

Nat Rev Clin Oncol 2012 Nov 11;9(11):621-30. Epub 2012 Sep 11.

Department of Medicine/Hematology and Oncology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1038/nrclinonc.2012.159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169265PMC
November 2012

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

BMC Cancer 2012 Oct 30;12:500. Epub 2012 Oct 30.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, 122 Hungerford Hill Road, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1186/1471-2407-12-500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571905PMC
October 2012