Joe G N Garcia

Joe G N Garcia

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Joe G N Garcia

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Genomic and Genetic Approaches to Deciphering Acute Respiratory Distress Syndrome Risk and Mortality.

Antioxid Redox Signal 2019 Nov 18;31(14):1027-1052. Epub 2019 Jun 18.

Department of Health Sciences, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1089/ars.2018.7701DOI Listing
November 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

New cases of Glucose-6-Phosphate Dehydrogenase deficiency in Pulmonary Arterial Hypertension.

PLoS One 2018 30;13(8):e0203493. Epub 2018 Aug 30.

Division of Endocrinology, Department of Medicine, College of Medicine, The University of Arizona, Tucson, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203493PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117081PMC
February 2019

Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2019 01 25;316(1):L216-L228. Epub 2018 Oct 25.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University , Guangzhou , China.

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http://dx.doi.org/10.1152/ajplung.00538.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383500PMC
January 2019

An update on sphingosine-1-phosphate receptor 1 modulators.

Bioorg Med Chem Lett 2018 12 26;28(23-24):3585-3591. Epub 2018 Oct 26.

Department of Chemistry & Biochemistry, The University of Arizona, Tucson, AZ 85721, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430570PMC
December 2018

Novel Mechanism for Nicotinamide Phosphoribosyltransferase Inhibition of TNF-α-mediated Apoptosis in Human Lung Endothelial Cells.

Am J Respir Cell Mol Biol 2018 07;59(1):36-44

1 Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Arizona Health Sciences, University of Arizona, Tucson, Arizona.

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https://www.atsjournals.org/doi/10.1165/rcmb.2017-0155OC
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http://dx.doi.org/10.1165/rcmb.2017-0155OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039874PMC
July 2018

The Splicing Factor hnRNPA1 Regulates Alternate Splicing of the MYLK Gene.

Am J Respir Cell Mol Biol 2018 05;58(5):604-613

1 Department of Medicine, College of Medicine, and.

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http://dx.doi.org/10.1165/rcmb.2017-0141OCDOI Listing
May 2018

Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation.

Free Radic Biol Med 2017 11 24;112:162-173. Epub 2017 Jul 24.

Department of Pharmacology, The University of Illinois at Chicago, Chicago, IL, USA; Department of Medicine, The University of Illinois at Chicago, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.07.023DOI Listing
November 2017

Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia-induced pulmonary hypertension.

Br J Pharmacol 2017 Nov 2;174(22):4155-4172. Epub 2017 Oct 2.

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

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http://dx.doi.org/10.1111/bph.13990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659991PMC
November 2017

Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature.

Sci Rep 2017 06 26;7(1):4237. Epub 2017 Jun 26.

Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Arizona Health Sciences, Tucson, AZ, 78721, USA.

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http://www.nature.com/articles/s41598-017-04109-6
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http://dx.doi.org/10.1038/s41598-017-04109-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484682PMC
June 2017

Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension.

Circulation 2017 04 15;135(16):1532-1546. Epub 2017 Feb 15.

From Division of Pulmonary, Critical Care Medicine, Sleep and Allergy, Department of Medicine (J.C., J.R.S., S.S., S.Z., A.Y., T.A., K.M.S., S.S., V.R., A.S., H.G., J.T., R.F.M.), Department of Pharmacology (J.R.S., R.F.M.), and Department of Bioengineering (A.V.-J., T.A.), University of Illinois at Chicago; Institute of Precision Medicine, Jining Medical University, China (J.C.); Department of Pharmacy, College of Pharmacy, Kinjo Gakuin University, Nagoya, Japan (A.Y.); Department of Medicine, Mercy Hospital and Medical Center, Chicago, IL (T.A.); Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (H.G.); Department of Medicine, University of Arizona, Tucson (S.M.C., H.T., J.X.-J.Y., J.G.N.G.); Department of Biomedical and Health Informatics and Department of Pediatrics, Children's Mercy Hospital and University of Missouri-Kansas City School of Medicine (S.Q.Y.); Department of Pathobiology, Lerner Research Institute, Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, OH (S.C., R.D.); and Division of Pulmonary and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD (P.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400780PMC
April 2017

Simvastatin-induced sphingosine 1-phosphate receptor 1 expression is KLF2-dependent in human lung endothelial cells.

Pulm Circ 2017 Mar 21;7(1):117-125. Epub 2017 Mar 21.

Department of Medicine, University of Arizona Health Sciences, Tucson, AZ, USA.

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http://dx.doi.org/10.1177/2045893217701162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448536PMC
March 2017

The ARP 2/3 complex mediates endothelial barrier function and recovery.

Pulm Circ 2017 Mar 1;7(1):200-210. Epub 2017 Feb 1.

Division of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois Hospital and Health Science System, Chicago, IL, USA.

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http://dx.doi.org/10.1086/690307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448540PMC
March 2017

High Positive End-Expiratory Pressure Is Associated with Improved Survival in Obese Patients with Acute Respiratory Distress Syndrome.

Am J Med 2017 Feb 28;130(2):207-213. Epub 2016 Oct 28.

Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of Arizona College of Medicine, Tucson; University of Arizona Health Sciences, Tucson.

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http://dx.doi.org/10.1016/j.amjmed.2016.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839112PMC
February 2017

A Transformative Approach to Academic Medicine: The Partnership Between the University of Arizona and Banner Health.

Acad Med 2017 01;92(1):20-22

C.B. Cairns is dean, College of Medicine-Tucson, and professor, Department of Emergency Medicine, University of Arizona Health Sciences, Tucson, Arizona. K. Bollinger is executive vice president, Banner - University Medicine, Phoenix, Arizona. J.G.N. Garcia is senior vice president for health sciences and Merlin K. DuVal, MD Professor of Medicine, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1097/ACM.0000000000001345DOI Listing
January 2017

Racial Differences in Mortality from Severe Acute Respiratory Failure in the United States, 2008-2012.

Ann Am Thorac Soc 2016 12;13(12):2184-2189

1 Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, and.

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http://dx.doi.org/10.1513/AnnalsATS.201605-359OCDOI Listing
December 2016

Expression profiling elucidates a molecular gene signature for pulmonary hypertension in sarcoidosis.

Pulm Circ 2016 Dec;6(4):465-471

Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1086/688316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210052PMC
December 2016

Endotoxin- and mechanical stress-induced epigenetic changes in the regulation of the nicotinamide phosphoribosyltransferase promoter.

Pulm Circ 2016 Dec;6(4):539-544

Department of Medicine, University of Arizona, Tucson, Arizona, USA; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1086/688761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210063PMC
December 2016

Reactive oxygen species-associated molecular signature predicts survival in patients with sepsis.

Pulm Circ 2016 Jun;6(2):196-201

Department of Medicine, University of Arizona, Tucson, Arizona, USA; Southern Arizona Veterans Administration Health Care System, Tucson, Arizona, USA.

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http://dx.doi.org/10.1086/685547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869924PMC
June 2016

Role of Nrf2 and Autophagy in Acute Lung Injury.

Curr Pharmacol Rep 2016 04 6;2(2):91-101. Epub 2016 Feb 6.

Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ, USA; Arizona Cancer Center, University of Arizona, Tucson, AZ, USA.

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http://dx.doi.org/10.1007/s40495-016-0053-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905711PMC
April 2016

Structure-Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants.

PLoS One 2015 25;10(6):e0130515. Epub 2015 Jun 25.

Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America; Arizona Respiratory Center and Department of Medicine, University of Arizona, Tucson, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130515PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482139PMC
March 2016

Nonmyeloablative Stem Cell Transplantation with Alemtuzumab/Low-Dose Irradiation to Cure and Improve the Quality of Life of Adults with Sickle Cell Disease.

Biol Blood Marrow Transplant 2016 Mar 5;22(3):441-8. Epub 2015 Sep 5.

Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois; University of Illinois Cancer Center, Chicago, Illinois; University of Illinois Center for Global Health, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2015.08.036DOI Listing
March 2016

Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene.

J Allergy Clin Immunol 2016 Mar 24;137(3):964-6. Epub 2015 Nov 24.

Research Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain; Applied Genomics Group (G2A), Genetics Laboratory, Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (CIBICAN), Universidad de La Laguna, Tenerife, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.09.051DOI Listing
March 2016

Plasma metabolomic profile in fibrosing pulmonary sarcoidosis.

Sarcoidosis Vasc Diffuse Lung Dis 2016 Mar 29;33(1):29-38. Epub 2016 Mar 29.

University of Illinois at Chicago.

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March 2016

Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing.

Transl Res 2016 Feb 7;168:22-39. Epub 2015 May 7.

Department of Medicine, University of Arizona, Tucson, Ariz; Center for Biomedical Informatics and Biostatistics, University of Arizona, Tucson, Ariz; BIO5 Institute, University of Arizona, Tucson, Ariz; University of Arizona Health Sciences Center, University of Arizona, Tucson, Ariz; Institute for Genomics and Systems Biology, Argonne National Laboratory and University of Chicago, Chicago, Ill. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2015.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658294PMC
February 2016

ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells.

Am J Physiol Cell Physiol 2016 Jan 21;310(2):C99-114. Epub 2015 Oct 21.

Department of Medicine, Division of Translational and Regenerative Medicine, College of Medicine, The University of Arizona, Tucson, Arizona; Department of Physiology, College of Medicine, The University of Arizona, Tucson, Arizona;

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http://dx.doi.org/10.1152/ajpcell.00092.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719033PMC
January 2016

"Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720".

Chem Phys Lipids 2016 Jan 29;194:85-93. Epub 2015 Oct 29.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago, Chicago, IL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2015.10.004DOI Listing
January 2016

Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner.

Sci Rep 2016 Jan 5;6:18760. Epub 2016 Jan 5.

Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ 85721, USA.

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http://dx.doi.org/10.1038/srep18760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700431PMC
January 2016

Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 2;309(11):L1294-304. Epub 2015 Oct 2.

University of Illinois Hospital and Health Sciences System, Division of Pulmonary, Critical Care, Sleep and Allergy, Chicago, Illinois; University of Illinois at Chicago, Department of Pharmacology, Chicago, Illinois;

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http://dx.doi.org/10.1152/ajplung.00031.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669340PMC
December 2015

Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 23;309(12):L1420-9. Epub 2015 Oct 23.

Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, Illinois;

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http://dx.doi.org/10.1152/ajplung.00146.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683317PMC
December 2015

Identifying Novel Biomarkers in Sarcoidosis Using Genome-Based Approaches.

Clin Chest Med 2015 Dec 26;36(4):621-630. Epub 2015 Sep 26.

University of Arizona Health Sciences Center, Arizona Respiratory Center and Department of Medicine, University of Arizona, Tucson, AZ 78721, USA.

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http://dx.doi.org/10.1016/j.ccm.2015.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990072PMC
December 2015

Sp1-mediated nonmuscle myosin light chain kinase expression and enhanced activity in vascular endothelial growth factor-induced vascular permeability.

Pulm Circ 2015 Dec;5(4):707-15

Department of Medicine and University of Arizona Respiratory Center, University of Arizona, Tucson, Arizona, USA.

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http://dx.doi.org/10.1086/684124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671745PMC
December 2015

A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing.

Am J Physiol Lung Cell Mol Physiol 2015 Nov 11;309(9):L983-94. Epub 2015 Sep 11.

Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana, Illinois; Department of Chemistry, University of Illinois, Urbana, Illinois

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http://dx.doi.org/10.1152/ajplung.00062.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628987PMC
November 2015

Role of Integrin β4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress.

Sci Rep 2015 Nov 17;5:16529. Epub 2015 Nov 17.

Division of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, IL.

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http://dx.doi.org/10.1038/srep16529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647208PMC
November 2015

GADD45a promoter regulation by a functional genetic variant associated with acute lung injury.

PLoS One 2014 18;9(6):e100169. Epub 2014 Jun 18.

Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100169PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062486PMC
October 2015

Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent.

J Allergy Clin Immunol 2015 Oct 27;136(4):1116-8.e9. Epub 2015 May 27.

CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Research Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain; Applied Genomics Group (G2A), Genetics Laboratory, Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Tenerife, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699578PMC
October 2015

Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720.

Chem Phys Lipids 2015 Oct 10;191:16-24. Epub 2015 Aug 10.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago, Chicago, IL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2015.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655823PMC
October 2015

A MYLK variant regulates asthmatic inflammation via alterations in mRNA secondary structure.

Eur J Hum Genet 2015 Jun 1;23(6):874-6. Epub 2014 Oct 1.

Arizona Respiratory Center and Department of Medicine, University of Arizona, Tucson, AZ, USA.

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http://dx.doi.org/10.1038/ejhg.2014.201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795064PMC
June 2015

'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine.

J Am Med Inform Assoc 2014 Nov-Dec;21(6):1015-25. Epub 2014 Jun 12.

Department of Medicine, Bio5 Institute, UA Cancer Center, University of Arizona, Tucson, Arizona, USA Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA Institute for Translational Health Informatics, University of Illinois at Chicago, Chicago, Illinois, USA Computation Institute, Argonne National Laboratory & University of Chicago, Chicago, Illinois, USA University of Illinois Cancer Center, Chicago, Illinois, USA Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA Department of Biopharmaceutical Science, College of Pharmacy, University of Illinois at Chicago, Illinois, USA Institute for Genomics and Systems Biology, University of Chicago, Chicago, Illinois, USA Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1136/amiajnl-2013-002519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215042PMC
May 2015

Rapid porcine lung decellularization using a novel organ regenerative control acquisition bioreactor.

ASAIO J 2015 Jan-Feb;61(1):71-7

From the *Division of Cardiothoracic Surgery, Department of Surgery, University of Arizona College of Medicine, Tucson, Arizona; †University of Arizona Medical Center, Tucson, Arizona; ‡Department of Physiology, University of Arizona College of Medicine, Tucson, Arizona; §Department of Biomedical Engineering, University of Arizona College of Medicine, Tucson, Arizona; and ¶University of Arizona College of Medicine, Tucson, Arizona.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MAT.0000000000000159DOI Listing
May 2015

c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.

Am J Physiol Lung Cell Mol Physiol 2015 May 20;308(10):L1025-38. Epub 2015 Mar 20.

Department of Pharmacology, University of Illinois, Chicago, Illinois; Department of Medicine, College of Medicine, University of Illinois, Chicago, Illinois;

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http://dx.doi.org/10.1152/ajplung.00306.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437005PMC
May 2015

Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate.

Microvasc Res 2015 May 7;99:102-9. Epub 2015 Apr 7.

Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mvr.2015.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032626PMC
May 2015

American medical education at a crossroads.

Sci Transl Med 2015 Apr;7(285):285fs17

University of Pennsylvania Raymond and Ruth Perelman School of Medicine, Philadelphia, PA 19140, USA.

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http://stm.sciencemag.org/content/7/285/285fs17.full-text.pd
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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.aaa20
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http://dx.doi.org/10.1126/scitranslmed.aaa2039DOI Listing
April 2015

Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2015 Jan 21;308(2):L208-20. Epub 2014 Nov 21.

Department of Medicine, Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona; Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy Medicine, University of Illinois at Chicago, Chicago, Illinois; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois; and

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http://ajplung.physiology.org/content/ajplung/308/2/L208.ful
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http://ajplung.physiology.org/lookup/doi/10.1152/ajplung.002
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http://dx.doi.org/10.1152/ajplung.00242.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338938PMC
January 2015

Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics.

Microvasc Res 2014 Sep 27;95:94-102. Epub 2014 Jul 27.

Division of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois Hospital and Health Science System, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mvr.2014.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188692PMC
September 2014

Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrence-free survival in lung and breast cancers.

Sci Rep 2014 Aug 22;4:6107. Epub 2014 Aug 22.

Arizona Respiratory Center and Department of Medicine, The University of Arizona, Tucson, Arizona, USA.

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http://dx.doi.org/10.1038/srep06107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141256PMC
August 2014

Pleiotropic effects of interleukin-6 in a "two-hit" murine model of acute respiratory distress syndrome.

Pulm Circ 2014 Jun;4(2):280-8

Institute of Personalized Respiratory Medicine, University of Illinois at Chicago, Chicago, Illinois, USA ; Office of the Vice President for Health Affairs, University of Illinois at Chicago, Chicago, Illinois, USA ; Current affiliation: Division of Pulmonary and Critical Care, Sleep Medicine, Arizona Respiratory Center, University of Arizona, Tucson, Arizona, USA.

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http://dx.doi.org/10.1086/675991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070787PMC
June 2014