Publications by authors named "Jody J Haigh"

61Publications

Modulating PKCα Activity to Target Wnt/β-Catenin Signaling in Colon Cancer.

Cancers (Basel) 2019 May 18;11(5). Epub 2019 May 18.

Campus Val d'Aurelle-Research team "Integrative cancer research for personalized medicine in digestive oncology", IRCM U1194, University of Montpellier, ICM, CNRS, CHU, 34298 Montpellier, France.

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https://www.mdpi.com/2072-6694/11/5/693
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http://dx.doi.org/10.3390/cancers11050693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563011PMC
May 2019

GNrep mouse: A reporter mouse for front-rear cell polarity.

Genesis 2019 06 16;57(6):e23299. Epub 2019 Apr 16.

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/dvg.23299
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http://dx.doi.org/10.1002/dvg.23299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618267PMC
June 2019

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.

Haematologica 2019 08 24;104(8):1608-1616. Epub 2019 Jan 24.

Mammalian Functional Genetics Group, Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3324/haematol.2018.207837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669144PMC
August 2019

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.

Acta Neuropathol 2018 01 5;135(1):131-148. Epub 2017 Aug 5.

Peripheral Neuropathy Research Group, Department of Biomedical Sciences and Institute Born Bunge, University of Antwerp, Universiteitsplein 1, 2610, Antwerpen, Belgium.

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http://dx.doi.org/10.1007/s00401-017-1756-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756276PMC
January 2018

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

J Vis Exp 2017 04 27(122). Epub 2017 Apr 27.

Department of Biomedical Molecular Biology, Ghent University; Inflammation Research Center, VIB; Center for Medical Genetics, Ghent University Hospital; Cancer Research Institute Ghent (CRIG);

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http://dx.doi.org/10.3791/55575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565114PMC
April 2017

The Snail Family in Normal and Malignant Haematopoiesis.

Cells Tissues Organs 2017 20;203(2):82-98. Epub 2017 Feb 20.

Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1159/000448655DOI Listing
May 2017

Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.

J Neuromuscul Dis 2016 05;3(2):183-200

Peripheral Neuropathy Group, VIB Department of Molecular Genetics and Institute Born Bunge, University of Antwerp, Antwerpen, Belgium.

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http://dx.doi.org/10.3233/JND-150144DOI Listing
May 2016

PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers.

Cancer Res 2016 06 28;76(11):3130-5. Epub 2016 Mar 28.

Goodman Cancer Research Centre, McGill University, Montréal, Québec, Canada. Division of Experimental Medicine, Department of Medicine, McGill University, Montréal, Québec, Canada. Department of Biochemistry, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891239PMC
June 2016

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection.

J Exp Med 2015 Nov 26;212(12):2015-25. Epub 2015 Oct 26.

Université de Lyon, 69007 Lyon, France Institut National de la Santé et de la Recherche Médicale, U1111, 69342 Lyon, France Ecole Normale Supérieure de Lyon, 69007 Lyon, France Centre International de Recherche en Infectiologie, 69007 Lyon, France Centre National de la Recherche Scientifique, UMR5308, 69342 Lyon, France

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http://dx.doi.org/10.1084/jem.20150809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647267PMC
November 2015

Müller Glia Are a Major Cellular Source of Survival Signals for Retinal Neurons in Diabetes.

Diabetes 2015 Oct 11;64(10):3554-63. Epub 2015 Jun 11.

Section of Endocrinology and Diabetes, Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK Department of Ophthalmology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK Harold Hamm Diabetes Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK

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http://dx.doi.org/10.2337/db15-0180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587642PMC
October 2015

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

Nat Commun 2015 Jan 7;6:5794. Epub 2015 Jan 7.

1] Vascular Cell Biology Unit, VIB Inflammation Research Center, Ghent University, Ghent B-9052, Belgium [2] Department for Biomedical Molecular Biology, Ghent University, Ghent B-9052, Belgium [3] Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre, 99 Commercial Road, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1038/ncomms6794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354161PMC
January 2015

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice.

Cell Cycle 2014 11;13(9):1501-7. Epub 2014 Mar 11.

Vascular Cell Biology Unit; Department for Molecular Biomedical Research; VIB-Ghent University; Ghent, Belgium; Department of Biomedical Molecular Biology; Ghent University; Ghent, Belgium; Australian Centre for Blood Diseases; Monash University; Melbourne, Victoria, Australia.

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http://dx.doi.org/10.4161/cc.28474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050148PMC
April 2016

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins.

Cell Mol Life Sci 2014 Sep 27;71(18):3599-609. Epub 2014 Feb 27.

Unit of Molecular and Cellular Oncology, Inflammation Research Center, VIB, Technologiepark 927, 9052, Ghent (Zwijnaarde), Belgium.

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http://dx.doi.org/10.1007/s00018-014-1589-0DOI Listing
September 2014

Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis.

PLoS One 2013 5;8(12):e79883. Epub 2013 Dec 5.

Department for Molecular Biomedical Research, VIB, Ghent, Belgium ; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079883PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855152PMC
March 2015

Endothelial VEGF sculpts cortical cytoarchitecture.

J Neurosci 2013 Sep;33(37):14809-15

Angiogenesis and Brain Development Laboratory, Division of Basic Neuroscience, McLean Hospital/Harvard Medical School, Belmont, Massachusetts 02478, Vascular Cell Biology Unit, Department for Molecular Biomedical Research, VIB, B-9052 Ghent, Belgium, Department for Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium, and Australian Centre for Blood Diseases, Monash University, Melbourne, VIC 3004, Australia.

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http://dx.doi.org/10.1523/JNEUROSCI.1368-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771035PMC
September 2013

Gata3 antagonizes cancer progression in Pten-deficient prostates.

Hum Mol Genet 2013 Jun 20;22(12):2400-10. Epub 2013 Feb 20.

Goodman Cancer Research Centre and Department of Biochemistry, McGill University, Montreal, Quebec, Canada H3A 1A3.

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http://dx.doi.org/10.1093/hmg/ddt088DOI Listing
June 2013

The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation.

Cell Rep 2013 Feb 7;3(2):335-41. Epub 2013 Feb 7.

Vascular Cell Biology Unit, VIB Department for Molecular Biomedical Research, Ghent University, Technologiepark 927, 9052 Zwijnaarde Ghent, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S22111247130002
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http://dx.doi.org/10.1016/j.celrep.2013.01.016DOI Listing
February 2013

Identification of a clonally expanding haematopoietic compartment in bone marrow.

EMBO J 2013 Jan 27;32(2):219-30. Epub 2012 Nov 27.

Department of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1038/emboj.2012.308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553379PMC
January 2013

MDM4 is a key therapeutic target in cutaneous melanoma.

Nat Med 2012 Aug 22;18(8):1239-47. Epub 2012 Jul 22.

Center for the Biology of Disease, Laboratory for Molecular Cancer Biology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium; Center for Human Genetics, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/nm.2863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744207PMC
August 2012

Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.

Mol Cell Biol 2010 Nov 20;30(22):5394-405. Epub 2010 Sep 20.

Laboratory for Molecular Cancer Biology, Department of Biomedical Molecular Biology, VIB-UGent, Technologiepark, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1128/MCB.00330-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976380PMC
November 2010

Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.

Nat Cell Biol 2010 Oct 19;12(10):963-72. Epub 2010 Sep 19.

Mammalian Genetics Laboratory, Cancer Research UK London Research Institute, Lincoln's Inn Fields Laboratories, 44, Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://www.nature.com/articles/ncb2098
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http://dx.doi.org/10.1038/ncb2098DOI Listing
October 2010

Role of VEGF in organogenesis.

Authors:
Jody J Haigh

Organogenesis 2008 Oct;4(4):247-56

Vascular Cell Biology Unit; Department for Molecular Biomedical Research; VIB; Department of Molecular Biology; Ghent University; Ghent Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634330PMC
http://dx.doi.org/10.4161/org.4.4.7415DOI Listing
October 2008

Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling.

Dev Biol 2008 May 21;317(1):121-31. Epub 2008 Feb 21.

Developmental Biology Program, Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1016/j.ydbio.2008.02.014DOI Listing
May 2008

Developmental and adult phenotyping directly from mutant embryonic stem cells.

Proc Natl Acad Sci U S A 2007 Mar 2;104(11):4455-60. Epub 2007 Mar 2.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5.

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http://dx.doi.org/10.1073/pnas.0609277104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838622PMC
March 2007

Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis.

Circ Res 2006 Sep 31;99(7):715-22. Epub 2006 Aug 31.

Department of Reproductive and Vascular Biology, Institute for Biomedical Research, The Medical School, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1161/01.RES.0000243989.46006.b9DOI Listing
September 2006

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells.

Blood 2004 Feb 2;103(3):912-20. Epub 2003 Oct 2.

Mount Sinai Hospital, Samuel Lunenfeld Research Institute, 600 University Ave, Toronto, Ontario, Canada M5G 1X5.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2003-07-23
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http://dx.doi.org/10.1182/blood-2003-07-2343DOI Listing
February 2004