Jochen Kruppa

Jochen Kruppa

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Jochen Kruppa

Jochen Kruppa

Publications by authors named "Jochen Kruppa"

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Validation of 3-minute diagnostic interview for CAM-defined Delirium to detect postoperative delirium in the recovery room: A prospective diagnostic study.

Eur J Anaesthesiol 2019 Sep;36(9):683-687

From the Department of Anesthesiology and Operative Intensive Care Medicine (MO, SE, RM, CDS) and Institute of Biometry and Clinical Epidemiology (JK), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Berlin Institute of Health (BIH), Berlin, Germany (MO, JK).

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http://dx.doi.org/10.1097/EJA.0000000000001048DOI Listing
September 2019

Human airway epithelial extracellular vesicle miRNA signature is altered upon asthma development.

Allergy 2019 Aug 6. Epub 2019 Aug 6.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, GRIAC Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/all.14008DOI Listing
August 2019

Emergence delirium in children is not related to intraoperative burst suppression - prospective, observational electrography study.

BMC Anesthesiol 2019 Aug 8;19(1):146. Epub 2019 Aug 8.

Department of Anaesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1186/s12871-019-0819-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688308PMC
August 2019

A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers.

Clin Epigenetics 2019 Jul 22;11(1):105. Epub 2019 Jul 22.

Department of Periodontology and Synoptic Dentistry, Institute for Dental and Craniofacial Sciences, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Aßmannshauser Str. 4-6, 14197, Berlin, Germany.

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http://dx.doi.org/10.1186/s13148-019-0697-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647091PMC
July 2019

Virus detection in high-throughput sequencing data without a reference genome of the host.

Infect Genet Evol 2018 12 3;66:180-187. Epub 2018 Oct 3.

Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Foundation, Bünteweg 17p, Hannover 30559, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S15671348183056
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http://dx.doi.org/10.1016/j.meegid.2018.09.026DOI Listing
December 2018

Evolutionary evidence for multi-host transmission of cetacean morbillivirus.

Emerg Microbes Infect 2018 Dec 5;7(1):201. Epub 2018 Dec 5.

Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.

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http://www.nature.com/articles/s41426-018-0207-x
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http://dx.doi.org/10.1038/s41426-018-0207-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279766PMC
December 2018

Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density.

J Clin Transl Endocrinol 2018 Sep 19;13:26-38. Epub 2018 Jun 19.

Clinic of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1016/j.jcte.2018.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039964PMC
September 2018

Canine Bocavirus Type 2 Infection Associated With Intestinal Lesions.

Vet Pathol 2018 05 8;55(3):434-441. Epub 2018 Feb 8.

2 Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany.

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http://journals.sagepub.com/doi/10.1177/0300985818755253
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http://dx.doi.org/10.1177/0300985818755253DOI Listing
May 2018

A Simple Test Identifies Selection on Complex Traits.

Genetics 2018 05 15;209(1):321-333. Epub 2018 Mar 15.

Center for Integrated Breeding Research, University of Göttingen, 37075, Germany

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http://dx.doi.org/10.1534/genetics.118.300857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937188PMC
May 2018

Novel canine circovirus strains from Thailand: Evidence for genetic recombination.

Sci Rep 2018 May 14;8(1):7524. Epub 2018 May 14.

Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine (TiHo-RIZ), Bünteweg 17, Hannover, 30559, Germany.

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http://dx.doi.org/10.1038/s41598-018-25936-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951951PMC
May 2018

A genetic algorithm for simulating correlated binary data from biomedical research.

Comput Biol Med 2018 01 31;92:1-8. Epub 2017 Oct 31.

Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Hannover, Germany; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2017.10.023DOI Listing
January 2018

Attitudes, practice, and experience of German dentists regarding repair restorations.

Clin Oral Investig 2017 May 2;21(4):1087-1093. Epub 2016 Jun 2.

Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1007/s00784-016-1859-3DOI Listing
May 2017

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Authors:
Philipp S Wild Janine F Felix Arne Schillert Alexander Teumer Ming-Huei Chen Maarten J G Leening Uwe Völker Vera Großmann Jennifer A Brody Marguerite R Irvin Sanjiv J Shah Setia Pramana Wolfgang Lieb Reinhold Schmidt Alice V Stanton Dörthe Malzahn Albert Vernon Smith Johan Sundström Cosetta Minelli Daniela Ruggiero Leo-Pekka Lyytikäinen Daniel Tiller J Gustav Smith Claire Monnereau Marco R Di Tullio Solomon K Musani Alanna C Morrison Tune H Pers Michael Morley Marcus E Kleber Jayashri Aragam Emelia J Benjamin Joshua C Bis Egbert Bisping Ulrich Broeckel Susan Cheng Jaap W Deckers Fabiola Del Greco M Frank Edelmann Myriam Fornage Lude Franke Nele Friedrich Tamara B Harris Edith Hofer Albert Hofman Jie Huang Alun D Hughes Mika Kähönen Knhi Investigators Jochen Kruppa Karl J Lackner Lars Lannfelt Rafael Laskowski Lenore J Launer Margrét Leosdottir Honghuang Lin Cecilia M Lindgren Christina Loley Calum A MacRae Deborah Mascalzoni Jamil Mayet Daniel Medenwald Andrew P Morris Christian Müller Martina Müller-Nurasyid Stefania Nappo Peter M Nilsson Sebastian Nuding Teresa Nutile Annette Peters Arne Pfeufer Diana Pietzner Peter P Pramstaller Olli T Raitakari Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Saku T Ruohonen Ralph L Sacco Tandaw E Samdarshi Helena Schmidt Andrew S P Sharp Denis C Shields Rossella Sorice Nona Sotoodehnia Bruno H Stricker Praveen Surendran Simon Thom Anna M Töglhofer André G Uitterlinden Rolf Wachter Henry Völzke Andreas Ziegler Thomas Münzel Winfried März Thomas P Cappola Joel N Hirschhorn Gary F Mitchell Nicholas L Smith Ervin R Fox Nicole D Dueker Vincent W V Jaddoe Olle Melander Martin Russ Terho Lehtimäki Marina Ciullo Andrew A Hicks Lars Lind Vilmundur Gudnason Burkert Pieske Anthony J Barron Robert Zweiker Heribert Schunkert Erik Ingelsson Kiang Liu Donna K Arnett Bruce M Psaty Stefan Blankenberg Martin G Larson Stephan B Felix Oscar H Franco Tanja Zeller Ramachandran S Vasan Marcus Dörr

J Clin Invest 2017 May 10;127(5):1798-1812. Epub 2017 Apr 10.

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https://www.jci.org/articles/view/84840
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http://dx.doi.org/10.1172/JCI84840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409098PMC
May 2017

Automated multigroup outlier identification in molecular high-throughput data using bagplots and gemplots.

BMC Bioinformatics 2017 May 2;18(1):232. Epub 2017 May 2.

Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Foundation, Bünteweg 17p, Hannover, D-30559, Germany.

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http://dx.doi.org/10.1186/s12859-017-1645-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414140PMC
May 2017

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

Authors:
Thomas R Webb Jeanette Erdmann Kathleen E Stirrups Nathan O Stitziel Nicholas G D Masca Henning Jansen Stavroula Kanoni Christopher P Nelson Paola G Ferrario Inke R König John D Eicher Andrew D Johnson Stephen E Hamby Christer Betsholtz Arno Ruusalepp Oscar Franzén Eric E Schadt Johan L M Björkegren Peter E Weeke Paul L Auer Ursula M Schick Yingchang Lu He Zhang Marie-Pierre Dube Anuj Goel Martin Farrall Gina M Peloso Hong-Hee Won Ron Do Erik van Iperen Jochen Kruppa Anubha Mahajan Robert A Scott Christina Willenborg Peter S Braund Julian C van Capelleveen Alex S F Doney Louise A Donnelly Rosanna Asselta Pier A Merlini Stefano Duga Nicola Marziliano Josh C Denny Christian Shaffer Nour Eddine El-Mokhtari Andre Franke Stefanie Heilmann Christian Hengstenberg Per Hoffmann Oddgeir L Holmen Kristian Hveem Jan-Håkan Jansson Karl-Heinz Jöckel Thorsten Kessler Jennifer Kriebel Karl L Laugwitz Eirini Marouli Nicola Martinelli Mark I McCarthy Natalie R Van Zuydam Christa Meisinger Tõnu Esko Evelin Mihailov Stefan A Escher Maris Alver Susanne Moebus Andrew D Morris Jarma Virtamo Majid Nikpay Oliviero Olivieri Sylvie Provost Alaa AlQarawi Neil R Robertson Karen O Akinsansya Dermot F Reilly Thomas F Vogt Wu Yin Folkert W Asselbergs Charles Kooperberg Rebecca D Jackson Eli Stahl Martina Müller-Nurasyid Konstantin Strauch Tibor V Varga Melanie Waldenberger Lingyao Zeng Rajiv Chowdhury Veikko Salomaa Ian Ford J Wouter Jukema Philippe Amouyel Jukka Kontto Børge G Nordestgaard Jean Ferrières Danish Saleheen Naveed Sattar Praveen Surendran Aline Wagner Robin Young Joanna M M Howson Adam S Butterworth John Danesh Diego Ardissino Erwin P Bottinger Raimund Erbel Paul W Franks Domenico Girelli Alistair S Hall G Kees Hovingh Adnan Kastrati Wolfgang Lieb Thomas Meitinger William E Kraus Svati H Shah Ruth McPherson Marju Orho-Melander Olle Melander Andres Metspalu Colin N A Palmer Annette Peters Daniel J Rader Muredach P Reilly Ruth J F Loos Alex P Reiner Dan M Roden Jean-Claude Tardif John R Thompson Nicholas J Wareham Hugh Watkins Cristen J Willer Nilesh J Samani Heribert Schunkert Panos Deloukas Sekar Kathiresan

J Am Coll Cardiol 2017 Feb;69(7):823-836

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts; Department of Medicine, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2016.11.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314135PMC
February 2017

Set-Based Test Procedures for the Functional Analysis of Protein Lists from Differential Analysis.

Methods Mol Biol 2016 ;1362:143-56

Department of Medical Statistics, Georg-August-University Göttingen, Humboldtallee 32, 37073, Göttingen, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3106-4_9DOI Listing
May 2016

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

Authors:
Nathan O Stitziel Kathleen E Stirrups Nicholas G D Masca Jeanette Erdmann Paola G Ferrario Inke R König Peter E Weeke Thomas R Webb Paul L Auer Ursula M Schick Yingchang Lu He Zhang Marie-Pierre Dube Anuj Goel Martin Farrall Gina M Peloso Hong-Hee Won Ron Do Erik van Iperen Stavroula Kanoni Jochen Kruppa Anubha Mahajan Robert A Scott Christina Willenberg Peter S Braund Julian C van Capelleveen Alex S F Doney Louise A Donnelly Rosanna Asselta Piera A Merlini Stefano Duga Nicola Marziliano Josh C Denny Christian M Shaffer Nour Eddine El-Mokhtari Andre Franke Omri Gottesman Stefanie Heilmann Christian Hengstenberg Per Hoffman Oddgeir L Holmen Kristian Hveem Jan-Håkan Jansson Karl-Heinz Jöckel Thorsten Kessler Jennifer Kriebel Karl L Laugwitz Eirini Marouli Nicola Martinelli Mark I McCarthy Natalie R Van Zuydam Christa Meisinger Tõnu Esko Evelin Mihailov Stefan A Escher Maris Alver Susanne Moebus Andrew D Morris Martina Müller-Nurasyid Majid Nikpay Oliviero Olivieri Louis-Philippe Lemieux Perreault Alaa AlQarawi Neil R Robertson Karen O Akinsanya Dermot F Reilly Thomas F Vogt Wu Yin Folkert W Asselbergs Charles Kooperberg Rebecca D Jackson Eli Stahl Konstantin Strauch Tibor V Varga Melanie Waldenberger Lingyao Zeng Aldi T Kraja Chunyu Liu George B Ehret Christopher Newton-Cheh Daniel I Chasman Rajiv Chowdhury Marco Ferrario Ian Ford J Wouter Jukema Frank Kee Kari Kuulasmaa Børge G Nordestgaard Markus Perola Danish Saleheen Naveed Sattar Praveen Surendran David Tregouet Robin Young Joanna M M Howson Adam S Butterworth John Danesh Diego Ardissino Erwin P Bottinger Raimund Erbel Paul W Franks Domenico Girelli Alistair S Hall G Kees Hovingh Adnan Kastrati Wolfgang Lieb Thomas Meitinger William E Kraus Svati H Shah Ruth McPherson Marju Orho-Melander Olle Melander Andres Metspalu Colin N A Palmer Annette Peters Daniel Rader Muredach P Reilly Ruth J F Loos Alex P Reiner Dan M Roden Jean-Claude Tardif John R Thompson Nicholas J Wareham Hugh Watkins Cristen J Willer Sekkar Kathiresan Panos Deloukas Nilesh J Samani Heribert Schunkert

N Engl J Med 2016 03 2;374(12):1134-44. Epub 2016 Mar 2.

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http://dx.doi.org/10.1056/NEJMoa1507652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850838PMC
March 2016

Early pneumonia and timing of antibiotic therapy in patients after nontraumatic out-of-hospital cardiac arrest.

Crit Care 2016 Feb 1;20:31. Epub 2016 Feb 1.

Clinic for Cardiology & Pneumology/Heart Center, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1186/s13054-016-1191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736704PMC
February 2016

The time interval between primary surgery and adjuvant therapy determines prognosis of oral squamous cell carcinomas.

Oral Oncol 2015 Nov 5;51(11):e82-e85. Epub 2015 Oct 5.

Department of Oral and Maxillofacial Surgery, University Medical Centre Goettingen, Goettingen, Germany.

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http://dx.doi.org/10.1016/j.oraloncology.2015.08.016DOI Listing
November 2015

Probability estimation with machine learning methods for dichotomous and multicategory outcome: theory.

Biom J 2014 Jul 29;56(4):534-63. Epub 2014 Jan 29.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, Haus 24, 23562 Lübeck, Germany.

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http://dx.doi.org/10.1002/bimj.201300068DOI Listing
July 2014

Loss-of-function mutations in APOC3, triglycerides, and coronary disease.

N Engl J Med 2014 Jul 18;371(1):22-31. Epub 2014 Jun 18.

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http://dx.doi.org/10.1056/NEJMoa1307095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180269PMC
July 2014

Probability estimation with machine learning methods for dichotomous and multicategory outcome: applications.

Biom J 2014 Jul 12;56(4):564-83. Epub 2014 Feb 12.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, Haus 24, 23562, Lübeck, Germany.

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http://doi.wiley.com/10.1002/bimj.201300077
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http://dx.doi.org/10.1002/bimj.201300077DOI Listing
July 2014

Risk estimation and risk prediction using machine-learning methods.

Hum Genet 2012 Oct 3;131(10):1639-54. Epub 2012 Jul 3.

Institut für Medizininsche Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Maria-Goeppert-Str. 1, 23562 Lübeck, Germany.

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http://dx.doi.org/10.1007/s00439-012-1194-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432206PMC
October 2012